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Our results confirmed the key role of electrostatic interactions during HSA adsorption, since oppositely charged surfaces were more effective in promoting protein adhesion. QCM\u2010D data revealed that crosslinking (CHI\/ALG)<jats:sub>5<\/jats:sub>CHI films allows HSA to become adsorbed in physiological conditions. Our results suggested that the biological potential of biopolymers and the mild conditions of the LbL technique turn these natural nanoassemblies into a suitable choice to be used as pH\u2010sensitive coatings. <jats:boxed-text content-type=\"graphic\" position=\"anchor\"><jats:graphic xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" mimetype=\"image\/jpeg\" position=\"anchor\" specific-use=\"enlarged-web-image\" xlink:href=\"graphic\/mgra001.jpg\"><jats:alt-text>magnified image<\/jats:alt-text><\/jats:graphic><\/jats:boxed-text><\/jats:p>","DOI":"10.1002\/mabi.201000193","type":"journal-article","created":{"date-parts":[[2010,10,29]],"date-time":"2010-10-29T13:37:29Z","timestamp":1288359449000},"page":"1444-1455","source":"Crossref","is-referenced-by-count":72,"title":["Crosslink Effect and Albumin Adsorption onto Chitosan\/Alginate Multilayered Systems: An in situ QCM\u2010D Study"],"prefix":"10.1002","volume":"10","author":[{"given":"Gabriela 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