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     <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a secondary analysis of the nuMoM2b\u2010Heart Health Study (HHS), a multi\u2010site prospective cohort study that enrolled nulliparous pregnant individuals in their first trimester who were followed during pregnancy and subsequently underwent a cardiovascular screening visit (HHS visit) 2\u20107 years after delivery. Individuals without chronic hypertension who developed HDP (gestational hypertension, preeclampsia without severe features, or preeclampsia with severe features) were included. The exposure was treatment with antihypertensive medication (oral or intravenous) during the pregnancy episode (pregnancy through 6 weeks postpartum). The primary outcome was stage 1 (blood pressure [BP] \u2265130\/80\u00a0mmHg) and stage 2 hypertension (BP \u2265140\/90\u00a0mmHg or use of antihypertensive medications) at the HHS visit, which was ascertained following a standardized research protocol. Multinomial logistic regression models estimated the association of antihypertensive medication use with incident hypertension, adjusted for co\u2010variates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 4484 individuals who underwent a follow\u2010up visit (mean follow\u2010up: 3.2\u00a0\u00b1\u00a01.8 years), 1007 (22.5%) had HDP during the nuMoM2b pregnancy and were included. Of those, 132 (13%) were treated with an antihypertensive medication during the pregnancy episode. Treated individuals had higher systolic (119\u00a0\u00b1\u00a013\u00a0vs. 114\u00a0\u00b1\u00a011\u00a0mmHg,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001) and diastolic (80\u00a0\u00b1\u00a012\u00a0vs. 74\u00a0\u00b1\u00a010\u00a0mmHg,\n                      <jats:italic>p<\/jats:italic>\n                      \u00a0&lt;\u00a00.001) BP at follow\u2010up. In multivariable regression, those treated with antihypertensive medications had 2.5\u2010fold (95% confidence interval [CI], 1.6\u20134.1) greater odds of stage 1 hypertension and 4.3\u2010fold (95% CI, 2.5\u20137.3) greater odds of stage 2 hypertension compared to those with HDP who were not treated with antihypertensive medications.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Among nulliparous individuals with HDP, treatment with antihypertensive medication during or immediately after pregnancy is associated with a two\u2010 to fourfold higher odds of incident hypertension in the years postpartum, independent of HDP type. The use of antihypertensive medication in the peripartum period may serve as an easily ascertainable risk marker to identify individuals at heightened risk of persistent hypertension who may benefit from targeted postpartum surveillance and intervention.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1002\/pmf2.70491","type":"journal-article","created":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T03:48:24Z","timestamp":1792986504000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Antihypertensive medications for individuals with hypertensive disorders of pregnancy and incident hypertension"],"prefix":"10.1002","volume":"2","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5009-7371","authenticated-orcid":false,"given":"Alisse","family":"Hauspurg","sequence":"first","affiliation":[{"name":"Warren Alpert Medical School at Brown University  Providence Rhode Island USA"},{"name":"Departemnt of Obstetrics, Gynecology and Reproductive Sciences University of Pittsburgh School of Medicine Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8379-0743","authenticated-orcid":false,"given":"David","family":"Haas","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Indiana University Indianapolis Indiana USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2927-8693","authenticated-orcid":false,"given":"Matthew K.","family":"Hoffman","sequence":"additional","affiliation":[{"name":"Department of Obstetrics &amp; Gynecology Columbia University  New York New York USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9933-5155","authenticated-orcid":false,"given":"Cathleen Noel Bairey","family":"Merz","sequence":"additional","affiliation":[{"name":"Barbra Streisand Women's Heart Center Smidt Heart Institute Cedars Sinai Medical Center  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela C.","family":"Ranzini","sequence":"additional","affiliation":[{"name":"The MetroHealth System\/Case Western Reserve University  Cleveland Ohio USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6274-0544","authenticated-orcid":false,"given":"Lynn M.","family":"Yee","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology Northwestern University Feinberg School of Medicine Chicago Illinois USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6811-7980","authenticated-orcid":false,"given":"Lisa","family":"Levine","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology University of Pennsylvania Perelman School of Medicine Philadelphia Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria","family":"Pemberton","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular Sciences, The National Heart, Lung, and Blood Institute NIH Bethesda Maryland USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9551-851X","authenticated-orcid":false,"given":"Janet","family":"Catov","sequence":"additional","affiliation":[{"name":"Departemnt of Obstetrics, Gynecology and Reproductive Sciences University of Pittsburgh School of Medicine Pittsburgh Pennsylvania USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wiliam","family":"Grobman","sequence":"additional","affiliation":[{"name":"Warren Alpert Medical School at Brown University  Providence Rhode Island USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,25]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000003891"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.116.003497"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2025.7802"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.119.013092"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000001212"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2015.01.019"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1161\/HYP.0000000000000249"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2023.21523"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000772"}],"container-title":["Pregnancy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pmf2.70491","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/full-xml\/10.1002\/pmf2.70491","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/pdf\/10.1002\/pmf2.70491","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T03:48:26Z","timestamp":1792986506000},"score":1,"resource":{"primary":{"URL":"https:\/\/obgyn.onlinelibrary.wiley.com\/doi\/10.1002\/pmf2.70491"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,10,25]]},"references-count":9,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,11]]}},"alternative-id":["10.1002\/pmf2.70491"],"URL":"https:\/\/doi.org\/10.1002\/pmf2.70491","archive":["Portico"],"relation":{},"ISSN":["2997-9684","2997-9684"],"issn-type":[{"value":"2997-9684","type":"print"},{"value":"2997-9684","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,10,25]]},"assertion":[{"value":"2026-05-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-10-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-10-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e70491"}}