{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T11:43:58Z","timestamp":1768736638600,"version":"3.49.0"},"reference-count":27,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[1999,2,1]],"date-time":"1999-02-01T00:00:00Z","timestamp":917827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[1999,2,1]],"date-time":"1999-02-01T00:00:00Z","timestamp":917827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[1999,2]]},"DOI":"10.1006\/bbrc.1999.0209","type":"journal-article","created":{"date-parts":[[2002,10,6]],"date-time":"2002-10-06T20:13:12Z","timestamp":1033935192000},"page":"289-294","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"title":["Structural and Functional Analysis of theLaMDR1Multidrug Resistance Gene inLeishmania amazonensis"],"prefix":"10.1006","volume":"255","author":[{"given":"Ken","family":"Katakura","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaki","family":"Iwanami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Ohtomo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Fujise","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshihisa","family":"Hashiguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1006\/bbrc.1999.0209_RF1","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1146\/annurev.mi.49.100195.002235","volume":"49","author":"Borst","year":"1995","journal-title":"Annu. Rev. Microbiol."},{"key":"10.1006\/bbrc.1999.0209_RF2","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1007\/BF02110334","volume":"27","author":"Ullman","year":"1995","journal-title":"J. Bioenerg. Biomembr."},{"key":"10.1006\/bbrc.1999.0209_RF3","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1146\/annurev.mi.45.100191.002221","volume":"45","author":"Beverley","year":"1991","journal-title":"Annu. Rev. Microbiol."},{"key":"10.1006\/bbrc.1999.0209_RF4","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/0169-4758(93)90135-3","volume":"9","author":"Ouellette","year":"1993","journal-title":"Parasitol. Today"},{"key":"10.1006\/bbrc.1999.0209_RF5","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1080\/00034983.1994.11812849","volume":"88","author":"Segovia","year":"1994","journal-title":"Ann. Trop. Med. Parasitol."},{"key":"10.1006\/bbrc.1999.0209_RF6","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1002\/j.1460-2075.1990.tb08206.x","volume":"9","author":"Ouellette","year":"1990","journal-title":"EMBO J."},{"key":"10.1006\/bbrc.1999.0209_RF7","doi-asserted-by":"crossref","first-page":"18427","DOI":"10.1016\/S0021-9258(18)55077-8","volume":"266","author":"Callahan","year":"1991","journal-title":"J. Biol. Chem."},{"key":"10.1006\/bbrc.1999.0209_RF8","doi-asserted-by":"crossref","first-page":"13033","DOI":"10.1073\/pnas.91.26.13033","volume":"91","author":"Muller","year":"1994","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1006\/bbrc.1999.0209_RF9","doi-asserted-by":"crossref","first-page":"11980","DOI":"10.1016\/S0021-9258(17)32670-4","volume":"269","author":"Papadopoulou","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1006\/bbrc.1999.0209_RF10","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1146\/annurev.cb.08.110192.000435","volume":"8","author":"Higgins","year":"1992","journal-title":"Annu. Rev. Cell Biol."},{"key":"10.1006\/bbrc.1999.0209_RF11","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1146\/annurev.mi.47.100193.001451","volume":"47","author":"Doige","year":"1993","journal-title":"Annu. Rev. Microbiol."},{"key":"10.1006\/bbrc.1999.0209_RF12","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1146\/annurev.bi.58.070189.001033","volume":"58","author":"Endicott","year":"1989","journal-title":"Annu. Rev. Biochem."},{"key":"10.1006\/bbrc.1999.0209_RF13","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1146\/annurev.bi.62.070193.002125","volume":"62","author":"Gottesman","year":"1993","journal-title":"Annu. Rev. Biochem."},{"key":"10.1006\/bbrc.1999.0209_RF14","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/0165-6147(94)90322-0","volume":"15","author":"Ruets","year":"1994","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1006\/bbrc.1999.0209_RF15","first-page":"2855","volume":"12","author":"Henderson","year":"1992","journal-title":"Mol. Cell. Biol."},{"key":"10.1006\/bbrc.1999.0209_RF16","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/0166-6851(93)90028-V","volume":"60","author":"Hendrickson","year":"1993","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1006\/bbrc.1999.0209_RF17","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/0166-6851(93)90131-G","volume":"60","author":"Chow","year":"1993","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1006\/bbrc.1999.0209_RF18","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1006\/expr.1995.1141","volume":"81","author":"Gueiros-Filho","year":"1995","journal-title":"Exp. Parasitol."},{"key":"10.1006\/bbrc.1999.0209_RF19","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/0166-6851(96)02580-7","volume":"77","author":"Ha","year":"1996","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1006\/bbrc.1999.0209_RF20","doi-asserted-by":"crossref","first-page":"2242","DOI":"10.1128\/iai.61.5.2242-2244.1993","volume":"58","author":"Katakura","year":"1993","journal-title":"Infect. Immun."},{"key":"10.1006\/bbrc.1999.0209_RF21","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/0166-6851(94)90113-9","volume":"65","author":"Papadopoulou","year":"1994","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1006\/bbrc.1999.0209_RF22","first-page":"1084","volume":"10","author":"Kapler","year":"1990","journal-title":"Mol. Cell. Biol."},{"key":"10.1006\/bbrc.1999.0209_RF23","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0166-6851(88)90149-1","volume":"31","author":"Fong","year":"1988","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1006\/bbrc.1999.0209_RF24","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/0166-6851(94)90136-8","volume":"64","author":"Wong","year":"1994","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1006\/bbrc.1999.0209_RF25","doi-asserted-by":"crossref","first-page":"24248","DOI":"10.1016\/S0021-9258(18)35757-0","volume":"267","author":"Ueda","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1006\/bbrc.1999.0209_RF26","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1016\/S0092-8674(00)81370-7","volume":"87","author":"van Helvoot","year":"1996","journal-title":"Cell"},{"key":"10.1006\/bbrc.1999.0209_RF27","doi-asserted-by":"crossref","first-page":"772","DOI":"10.1006\/bbrc.1996.1098","volume":"224","author":"Papadopoulou","year":"1996","journal-title":"Biochem. Biophys. Res. Commun."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X99902097?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X99902097?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T14:04:26Z","timestamp":1762092266000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X99902097"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,2]]},"references-count":27,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1999,2]]}},"alternative-id":["S0006291X99902097"],"URL":"https:\/\/doi.org\/10.1006\/bbrc.1999.0209","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[1999,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Structural and Functional Analysis of theLaMDR1Multidrug Resistance Gene inLeishmania amazonensis","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1006\/bbrc.1999.0209","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1999 Academic Press. All rights reserved.","name":"copyright","label":"Copyright"}]}}