{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T06:05:53Z","timestamp":1779084353740,"version":"3.51.4"},"reference-count":23,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2000,2,1]],"date-time":"2000-02-01T00:00:00Z","timestamp":949363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2000,2,1]],"date-time":"2000-02-01T00:00:00Z","timestamp":949363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001700","name":"Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100017391","name":"Japan Private School Promotion Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100017391","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2000,2]]},"DOI":"10.1006\/bbrc.2000.2207","type":"journal-article","created":{"date-parts":[[2002,9,16]],"date-time":"2002-09-16T10:49:19Z","timestamp":1032173359000},"page":"904-908","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":55,"title":["Characterization of Endopeptidase Activity of Tripeptidyl Peptidase-I\/CLN2 Protein Which Is Deficient in Classical Late Infantile Neuronal Ceroid Lipofuscinosis"],"prefix":"10.1006","volume":"268","author":[{"given":"Junji","family":"Ezaki","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsue","family":"Takeda-Ezaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kohei","family":"Oda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eiki","family":"Kominami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1006\/bbrc.2000.2207_RF1","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1002\/ajmg.1320310606","volume":"5","author":"Rider","year":"1988","journal-title":"Am. J. Med. Genet. Suppl."},{"key":"10.1006\/bbrc.2000.2207_RF2","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/S0140-6736(99)00173-7","volume":"354","author":"Mole","year":"1999","journal-title":"Lancet"},{"key":"10.1006\/bbrc.2000.2207_RF3","doi-asserted-by":"crossref","first-page":"5736","DOI":"10.1016\/S0021-9258(18)83610-9","volume":"264","author":"Palmer","year":"1989","journal-title":"J. Biol. Chem."},{"key":"10.1006\/bbrc.2000.2207_RF4","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1042\/bj2750269","volume":"275","author":"Hall","year":"1991","journal-title":"Biochem. J."},{"key":"10.1006\/bbrc.2000.2207_RF5","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1093\/oxfordjournals.jbchem.a123749","volume":"111","author":"Kominami","year":"1992","journal-title":"J. Biochem. (Tokyo)"},{"key":"10.1006\/bbrc.2000.2207_RF6","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1046\/j.1471-4159.1995.64020733.x","volume":"64","author":"Ezaki","year":"1995","journal-title":"J. Neurochem."},{"key":"10.1006\/bbrc.2000.2207_RF7","doi-asserted-by":"crossref","first-page":"1677","DOI":"10.1046\/j.1471-4159.1996.67041677.x","volume":"67","author":"Ezaki","year":"1996","journal-title":"J. Neurochem."},{"key":"10.1006\/bbrc.2000.2207_RF8","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1055\/s-2007-973668","volume":"28","author":"Ezaki","year":"1997","journal-title":"Neuropediatrics"},{"key":"10.1006\/bbrc.2000.2207_RF9","doi-asserted-by":"crossref","first-page":"1802","DOI":"10.1126\/science.277.5333.1802","volume":"277","author":"Sleat","year":"1997","journal-title":"Science"},{"key":"10.1006\/bbrc.2000.2207_RF10","doi-asserted-by":"crossref","first-page":"26518","DOI":"10.1016\/S0021-9258(18)47225-0","volume":"269","author":"Oda","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1006\/bbrc.2000.2207_RF11","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1093\/oxfordjournals.jbchem.a021451","volume":"120","author":"Oda","year":"1996","journal-title":"J. Biochem."},{"key":"10.1006\/bbrc.2000.2207_RF12","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1046\/j.1471-4159.1999.0730700.x","volume":"73","author":"Sohar","year":"1999","journal-title":"J. Neurochem."},{"key":"10.1006\/bbrc.2000.2207_RF13","doi-asserted-by":"crossref","first-page":"2573","DOI":"10.1046\/j.1471-4159.1999.0722573.x","volume":"72","author":"Ezaki","year":"1999","journal-title":"J. Neurochem."},{"key":"10.1006\/bbrc.2000.2207_RF14","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S0167-4838(98)00012-0","volume":"1384","author":"Vines","year":"1998","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1006\/bbrc.2000.2207_RF15","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S0014-5793(98)01683-4","volume":"443","author":"Vines","year":"1999","journal-title":"FEBS Lett."},{"key":"10.1006\/bbrc.2000.2207_RF16","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1016\/S0167-4838(98)00238-6","volume":"1429","author":"Rawlings","year":"1999","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1006\/bbrc.2000.2207_RF17","first-page":"405","volume":"53","author":"Oda","year":"1989","journal-title":"Agric. Biol. Chem."},{"key":"10.1006\/bbrc.2000.2207_RF18","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1016\/0076-6879(95)51142-3","volume":"251","author":"Katunuma","year":"1995","journal-title":"Methods Enzymol."},{"key":"10.1006\/bbrc.2000.2207_RF19","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1093\/oxfordjournals.jbchem.a022396","volume":"125","author":"Yasuda","year":"1999","journal-title":"J. Biochem."},{"key":"10.1006\/bbrc.2000.2207_RF20","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1006\/abbi.1993.1361","volume":"304","author":"Takeda-Ezaki","year":"1993","journal-title":"Arch. Biochim. Biophys."},{"key":"10.1006\/bbrc.2000.2207_RF21","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1093\/oxfordjournals.jbchem.a022271","volume":"125","author":"Narutataki","year":"1995","journal-title":"J. Biochem."},{"key":"10.1006\/bbrc.2000.2207_RF22","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1093\/oxfordjournals.jbchem.a022160","volume":"124","author":"Shibata","year":"1998","journal-title":"J. Biochem."},{"key":"10.1006\/bbrc.2000.2207_RF23","doi-asserted-by":"crossref","first-page":"27815","DOI":"10.1074\/jbc.274.39.27815","volume":"274","author":"Oyama","year":"1999","journal-title":"J. Biol. Chem."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X00922071?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X00922071?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T14:03:51Z","timestamp":1762092231000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X00922071"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,2]]},"references-count":23,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2000,2]]}},"alternative-id":["S0006291X00922071"],"URL":"https:\/\/doi.org\/10.1006\/bbrc.2000.2207","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2000,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Characterization of Endopeptidase Activity of Tripeptidyl Peptidase-I\/CLN2 Protein Which Is Deficient in Classical Late Infantile Neuronal Ceroid Lipofuscinosis","name":"articletitle","label":"Article Title"},{"value":"Biochemical and Biophysical Research Communications","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1006\/bbrc.2000.2207","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2000 Academic Press. All rights reserved.","name":"copyright","label":"Copyright"}]}}