{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T18:46:56Z","timestamp":1773427616899,"version":"3.50.1"},"reference-count":19,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2001,5,1]],"date-time":"2001-05-01T00:00:00Z","timestamp":988675200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2001,5]]},"DOI":"10.1006\/bbrc.2001.4914","type":"journal-article","created":{"date-parts":[[2002,9,16]],"date-time":"2002-09-16T13:50:03Z","timestamp":1032184203000},"page":"1046-1053","source":"Crossref","is-referenced-by-count":38,"title":["Regional and Developmental Expression of Epm2a Gene and Its Evolutionary Conservation"],"prefix":"10.1006","volume":"283","author":[{"given":"Subramaniam","family":"Ganesh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kishan Lal","family":"Agarwala","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenji","family":"Amano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshimitsu","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio V","family":"Delgado-Escueta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuhiro","family":"Yamakawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1006\/bbrc.2001.4914_RF1","series-title":"The Epilepsies. Handbook of Clinical Neurology","first-page":"382","article-title":"Lafora disease, a form of progressive myoclonus epilepsy","author":"Van Heycop Ten Ham","year":"1975"},{"key":"10.1006\/bbrc.2001.4914_RF2","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1038\/2470","article-title":"Mutations in a gene encoding a novel protein tyrosine phosphatase cause progressive myoclonus epilepsy","volume":"2","author":"Minassian","year":"1998","journal-title":"Nat. Genet."},{"key":"10.1006\/bbrc.2001.4914_RF3","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1093\/hmg\/8.2.345","article-title":"A novel protein tyrosine phosphatase gene is mutated in progressive myoclonus epilepsy of the Lafora type (EPM2)","volume":"2","author":"Serratosa","year":"1999","journal-title":"Hum. Mol. Genet."},{"key":"10.1006\/bbrc.2001.4914_RF4","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1212\/WNL.54.2.488","article-title":"Identification of new and common mutations in the EPM2A gene in Lafora's disease","volume":"54","author":"Minassian","year":"2000","journal-title":"Neurology"},{"key":"10.1006\/bbrc.2001.4914_RF5","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1212\/WNL.55.3.341","article-title":"Mutation spectrum and predicted function of laforin in Lafora's progressive myoclonus epilepsy","volume":"55","author":"Minassian","year":"2000","journal-title":"Neurology"},{"key":"10.1006\/bbrc.2001.4914_RF6","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1038\/sj.ejhg.5200571","article-title":"Mutational spectrum of the EPM2A gene in progressive myoclonus epilepsy of Lafora: High degree of allelic heterogeneity and prevalence of deletions","volume":"8","author":"Gomez-Garre","year":"2000","journal-title":"Eur. J. Hum. Genet."},{"key":"10.1006\/bbrc.2001.4914_RF7","doi-asserted-by":"crossref","first-page":"2251","DOI":"10.1093\/oxfordjournals.hmg.a018916","article-title":"Laforin, defective in the progressive myoclonus epilepsy of lafora type, is a dual-specificity phosphatase associated with polyribosomes","volume":"9","author":"Ganesh","year":"2000","journal-title":"Hum. Mol. Genet."},{"key":"10.1006\/bbrc.2001.4914_RF8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0378-1119(98)00513-7","article-title":"Protein tyrosine phosphatase: Counting the trees in the forest","volume":"225","author":"Van Huijsduijnen","year":"1998","journal-title":"Gene"},{"key":"10.1006\/bbrc.2001.4914_RF9","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1038\/ng0696-175","article-title":"A gene mutated in X-linked myotubular myopathy defines a new putative tyrosine phosphatase family conserved in yeast","volume":"13","author":"Laporte","year":"1996","journal-title":"Nat. Genet."},{"key":"10.1006\/bbrc.2001.4914_RF10","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1038\/75542","article-title":"Charcot-Marie-Tooth type 4B is caused by mutations in the gene encoding myotubularin-related protein-2","volume":"25","author":"Bolino","year":"2000","journal-title":"Nat. Genet."},{"key":"10.1006\/bbrc.2001.4914_RF11","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1006\/bbrc.1999.0402","article-title":"Isolation and characterization of mouse homologue of the human epilepsy gene, EPM2A","volume":"257","author":"Ganesh","year":"1999","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1006\/bbrc.2001.4914_RF12","series-title":"Molecular Cloning. A Laboratory Manual","author":"Sambrook","year":"1989"},{"key":"10.1006\/bbrc.2001.4914_RF13","series-title":"Cells. A Laboratory Manual","author":"Spector","year":"1998"},{"key":"10.1006\/bbrc.2001.4914_RF14","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1006\/bbrc.2001.4420","article-title":"DSCAM, a highly conserved gene in mammals, expressed in differentiating mouse brain","volume":"281","author":"Agarwala","year":"2001","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1006\/bbrc.2001.4914_RF15","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1007\/BF00292332","article-title":"A rat genetic linkage map and comparative maps for mouse or human homologous rat genes","volume":"5","author":"Yamada","year":"1994","journal-title":"Mamm. Genome"},{"key":"10.1006\/bbrc.2001.4914_RF16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1538\/expanim.47.1","article-title":"A comparative genetic map of rat, mouse and human genomes","volume":"47","author":"Serikawa","year":"1998","journal-title":"Exp. Anim."},{"key":"10.1006\/bbrc.2001.4914_RF17","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1001\/archneur.1971.00490060017002","article-title":"Myoclonic epilepsy with Lafora bodies. Some ultrastructural, histochemical, and biochemical aspects","volume":"25","author":"Gambetti","year":"1971","journal-title":"Arch. Neurol."},{"key":"10.1006\/bbrc.2001.4914_RF18","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1001\/archneur.1968.00480010033002","article-title":"Studies on myoclonus epilepsy (Lafora body forms). I. Isolation and preliminary characterization of Lafora bodies in two cases","volume":"19","author":"Yokoi","year":"1968","journal-title":"Arch. Neurol."},{"key":"10.1006\/bbrc.2001.4914_RF19","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1212\/WNL.20.2.160","article-title":"Studies on myoclonus epilepsy (Lafora body form). II. Polyglucosans in the systemic deposits of myoclonus epilepsy and in corpora amylacea","volume":"20","author":"Sakai","year":"1970","journal-title":"Neurology"}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X01949149?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X01949149?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,8]],"date-time":"2019-05-08T10:54:41Z","timestamp":1557312881000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X01949149"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,5]]},"references-count":19,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2001,5]]}},"alternative-id":["S0006291X01949149"],"URL":"https:\/\/doi.org\/10.1006\/bbrc.2001.4914","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2001,5]]}}}