{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T17:45:25Z","timestamp":1789148725270,"version":"build-2803163510"},"reference-count":25,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2001,6,1]],"date-time":"2001-06-01T00:00:00Z","timestamp":991353600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2001,6]]},"DOI":"10.1006\/bbrc.2001.4998","type":"journal-article","created":{"date-parts":[[2002,9,16]],"date-time":"2002-09-16T09:50:03Z","timestamp":1032169803000},"page":"650-654","source":"Crossref","is-referenced-by-count":14,"title":["A New Locus for a Dominant Form of Multinodular Goiter on 3q26.1-q26.3"],"prefix":"10.1006","volume":"284","author":[{"given":"Tsutomu","family":"Takahashi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun-ichi","family":"Nozaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masaki","family":"Komatsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhiko","family":"Wada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maki","family":"Utsunomiya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kayoko","family":"Inoue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Goro","family":"Takada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akio","family":"Koizumi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1006\/bbrc.2001.4998_RF1","unstructured":"Ingbar, S. H., and Woeber, K. A.1968The thyroid glandInTextbook of Endocrinology (Williams, R. H., Eds.), pp. 105\u2013279, WB Saunders, Philadelphia, PA."},{"key":"10.1006\/bbrc.2001.4998_RF2","unstructured":"World Health Organization, 1993, Global prevalence of iodine deficiency disorders. Micronutrient Deficiency Information System working paper 1, WHO-Nutrition Unit, Geneva."},{"key":"10.1006\/bbrc.2001.4998_RF3","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1056\/NEJM195412092512403","article-title":"Significance of solitary non-toxic thyroid nodules","volume":"251","author":"Vander","year":"1954","journal-title":"N. Eng. J. Med."},{"key":"10.1006\/bbrc.2001.4998_RF4","first-page":"175","article-title":"Genetic and non genetic factors in simple goiter formation: Evidence from twin study","volume":"36","author":"Greig","year":"1967","journal-title":"Q. J. Med."},{"key":"10.1006\/bbrc.2001.4998_RF5","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1210\/jcem-26-10-1039","article-title":"Unusual familial goiter associated with intrathyroid calcification","volume":"26","author":"Murray","year":"1966","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1006\/bbrc.2001.4998_RF6","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1086\/301610","article-title":"Familial nontoxic multinodular thyroid goiter locus maps to chromosome 14q but does not account for familial nonmedullary thyroid cancer","volume":"61","author":"Bignell","year":"1997","journal-title":"Am. J. Human. Genet."},{"key":"10.1006\/bbrc.2001.4998_RF7","first-page":"811","article-title":"An autosomal dominant form of adolescent multiple goiter","volume":"39","author":"Couch","year":"1986","journal-title":"Am. J. Hum. Genet."},{"key":"10.1006\/bbrc.2001.4998_RF8","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1210\/jcem.82.2.3789","article-title":"Two families with an autosomal dominant inheritance pattern of papillary carcinoma of the thyroid","volume":"82","author":"Burgess","year":"1997","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1006\/bbrc.2001.4998_RF9","first-page":"3750","article-title":"Linkage of familial euthyroid goiter-1 locus and exclusion of the candidate genes thyroglobulin, thyroperoxidase, and Na+\/I-symporter","volume":"84","author":"Neumann","year":"1999","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1006\/bbrc.2001.4998_RF10","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1038\/bjc.1987.36","article-title":"Thyroid cancer among young women related to prior thyroid disease and pregnancy history","volume":"55","author":"Person-Martin","year":"1987","journal-title":"Br. J. Cancer"},{"key":"10.1006\/bbrc.2001.4998_RF11","first-page":"1","article-title":"A population-based study of thyroid cancer","volume":"79","author":"Ron","year":"1987","journal-title":"J. Natl. Cancer Inst."},{"key":"10.1006\/bbrc.2001.4998_RF12","first-page":"460","article-title":"Easy calculations of LOD scores and genetic risks on small computers","volume":"36","author":"Lathrop","year":"1984","journal-title":"Am. J. Hum. Genet."},{"key":"10.1006\/bbrc.2001.4998_RF13","first-page":"1347","article-title":"Paramteric and nonparametric linkage analysis: A unified multipoint approach","volume":"58","author":"Kruglyak","year":"1996","journal-title":"Am. J. Hum. Genet."},{"key":"10.1006\/bbrc.2001.4998_RF14","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1007\/s004390050917","article-title":"Mapping and genomic characterization of the gene encoding diacylglycerol kinase \u03b3 (DAGK3): Assessment of its role in dominant optic atrophy (OPA1)","volume":"104","author":"Stohr","year":"1999","journal-title":"Human Genet."},{"key":"10.1006\/bbrc.2001.4998_RF15","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1086\/303095","article-title":"Mapping a dominant form of multinodular goiter to chromosome Xp22","volume":"67","author":"Capon","year":"2000","journal-title":"Am. J. Hum. Genet."},{"key":"10.1006\/bbrc.2001.4998_RF16","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1172\/JCI115981","article-title":"Identification of a mutation in the coding sequences of the human thyroid peroxidase gene causing congenital goiter","volume":"90","author":"Abramowicz","year":"1992","journal-title":"J. Clin. Invest."},{"key":"10.1006\/bbrc.2001.4998_RF17","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.1172\/JCI115513","article-title":"A 3\u2032 splice site mutation in the thyroglobulin gene responsible for congenital goiter with hypothyroidism","volume":"88","author":"Ieiri","year":"1991","journal-title":"J. Clin. Invest."},{"key":"10.1006\/bbrc.2001.4998_RF18","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1016\/0140-6736(93)90209-Y","article-title":"Throglobulin gene point mutation associated with non-endemic multiple goiter","volume":"314","author":"Corral","year":"1993","journal-title":"Lancet"},{"key":"10.1006\/bbrc.2001.4998_RF19","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1038\/ng0697-124","article-title":"Congenital hypothyroidism caused by a mutation in Na+\/I-symporter","volume":"16","author":"Fujiwara","year":"1997","journal-title":"Nat. Genet."},{"key":"10.1006\/bbrc.2001.4998_RF20","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1038\/7783","article-title":"the Pendred syndrome gene encodes a chloride-iodide transport protein","volume":"21","author":"Scott","year":"1999","journal-title":"Nat. Genet."},{"key":"10.1006\/bbrc.2001.4998_RF21","first-page":"2577","article-title":"Genetic basis of endocrine diseases:somatioc and germline mutations of the TSH receptor gene in thyroid diseases","volume":"80","author":"Van Sande","year":"1995","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1006\/bbrc.2001.4998_RF22","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1038\/ng1297-411","article-title":"Pendred syndrome is caused by mutations in a putative sulphate transporteer gene (PDS)","volume":"17","author":"Everett","year":"1997","journal-title":"Nat. Genet."},{"key":"10.1006\/bbrc.2001.4998_RF23","first-page":"1133","article-title":"Cloning and in vitro expression of human selenoprotein, type I iodothyronine deiodinase","volume":"75","author":"Mandel","year":"1992","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1006\/bbrc.2001.4998_RF24","doi-asserted-by":"crossref","first-page":"2421","DOI":"10.1172\/JCI118299","article-title":"Type 3 iodothyronine deiodinase: Cloning, in vitro expression, and functional analysis of the placental selenoenzyme","volume":"96","author":"Salvatore","year":"1995","journal-title":"J. Clin. Invest."},{"key":"10.1006\/bbrc.2001.4998_RF25","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1172\/JCI118806","article-title":"Cloning of the mammalian type II iodothyronine deiodinase: a selenoprotein differentially expressed and regulated in human and rat brain and other tissues","volume":"98","author":"Croteau","year":"1996","journal-title":"J. Clin. Invest."}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X01949988?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X01949988?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,8]],"date-time":"2019-05-08T05:30:33Z","timestamp":1557293433000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X01949988"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,6]]},"references-count":25,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2001,6]]}},"alternative-id":["S0006291X01949988"],"URL":"https:\/\/doi.org\/10.1006\/bbrc.2001.4998","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2001,6]]}}}