{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,27]],"date-time":"2025-06-27T06:23:14Z","timestamp":1751005394491},"reference-count":15,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2001,11,1]],"date-time":"2001-11-01T00:00:00Z","timestamp":1004572800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemical and Biophysical Research Communications"],"published-print":{"date-parts":[[2001,11]]},"DOI":"10.1006\/bbrc.2001.5983","type":"journal-article","created":{"date-parts":[[2002,9,16]],"date-time":"2002-09-16T13:50:03Z","timestamp":1032184203000},"page":"389-394","source":"Crossref","is-referenced-by-count":10,"title":["Characterization of Surface Antigen from Lyme Disease Spirochete Borrelia burgdorferi"],"prefix":"10.1006","volume":"289","author":[{"given":"Kathryn","family":"Jones","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jesse","family":"Guidry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pernilla","family":"Wittung-Stafshede","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1006\/bbrc.2001.5983_RF1","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/S0952-7915(96)80038-0","article-title":"Immunity to Lyme disease: Protection, pathology and persistence","volume":"8","author":"Seiler","year":"1996","journal-title":"Curr. Opin. Immunol."},{"key":"10.1006\/bbrc.2001.5983_RF2","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1056\/NEJM198908313210906","article-title":"Lyme disease","volume":"321","author":"Steere","year":"1989","journal-title":"N. Engl. J. Med."},{"key":"10.1006\/bbrc.2001.5983_RF3","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/S0092-8674(00)80206-8","article-title":"Antigenic variation in Lyme disease borreliae by promiscuous recombination of VMP-like sequence cassettes","volume":"89","author":"Zhang","year":"1997","journal-title":"Cell"},{"key":"10.1006\/bbrc.2001.5983_RF4","doi-asserted-by":"crossref","first-page":"5566","DOI":"10.4049\/jimmunol.163.10.5566","article-title":"An immunodominant conserved region within the variable domain of VlsE, the variable surface antigen of Borrelia burgdorferi","volume":"163","author":"Liang","year":"1999","journal-title":"J. Immunol."},{"key":"10.1006\/bbrc.2001.5983_RF5","unstructured":"Liang, F. T, and, Philipp, M. T. 1999, Analysis of antibody response to invariable regions of VlsE, the variable surface antigen of Borrelia burgdorferi, Infect. Immun. 67, 6702."},{"key":"10.1006\/bbrc.2001.5983_RF6","doi-asserted-by":"crossref","first-page":"3990","DOI":"10.1128\/JCM.37.12.3990-3996.1999","article-title":"Sensitive and specific serodiagnosis of Lyme disease by enzyme-linked immunosorbent assay with a peptide based on an immunodominant conserved region of Borrelia burgdorferi vlsE","volume":"37","author":"Liang","year":"1999","journal-title":"J. Clin. Microbiol."},{"key":"10.1006\/bbrc.2001.5983_RF7","doi-asserted-by":"crossref","first-page":"3584","DOI":"10.1073\/pnas.94.8.3584","article-title":"Crystal structure of Lyme disease antigen outer surface protein A complexed with an Fab","volume":"94","author":"Li","year":"1997","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1006\/bbrc.2001.5983_RF8","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1093\/emboj\/20.5.971","article-title":"Crystal structure of outer surface protein C (OspC) from the Lyme disease spirochete, Borrelia burgdorferi","volume":"20","author":"Kumaran","year":"2001","journal-title":"EMBO J."},{"key":"10.1006\/bbrc.2001.5983_RF9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/10409237509102551","article-title":"The stability of globular proteins","volume":"3","author":"Pace","year":"1975","journal-title":"CRC Crit. Rev. Biochem."},{"key":"10.1006\/bbrc.2001.5983_RF10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0065-3233(08)60241-7","article-title":"Protein denaturation. C. Theoretical models for the mechanism of denaturation","volume":"24","author":"Tanford","year":"1970","journal-title":"Adv. Protein Chem."},{"key":"10.1006\/bbrc.2001.5983_RF11","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1002\/prot.340070302","article-title":"Protein secondary structure and circular dichroism: A practical guide","volume":"7","author":"Johnson","year":"1990","journal-title":"Proteins"},{"key":"10.1006\/bbrc.2001.5983_RF12","doi-asserted-by":"crossref","first-page":"8063","DOI":"10.1021\/bi00421a014","article-title":"Unfolding free energy changes determined by the linear extrapolation method. 1. Unfolding of phenylmethanesulfonyl alpha-chymotrypsin using different denaturants","volume":"27","author":"Santoro","year":"1988","journal-title":"Biochemistry"},{"key":"10.1006\/bbrc.2001.5983_RF13","doi-asserted-by":"crossref","first-page":"R81","DOI":"10.1016\/S1359-0278(98)00033-9","article-title":"How do small single-domain proteins fold?","volume":"3","author":"Jackson","year":"1998","journal-title":"Fold Des."},{"key":"10.1006\/bbrc.2001.5983_RF14","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1128\/JCM.38.1.382-388.2000","article-title":"Temporal changes in outer surface proteins A and C of the lyme disease-associated spirochete, Borrelia burgdorferi, during the chain of infection in ticks and mice","volume":"38","author":"Schwan","year":"2000","journal-title":"J. Clin. Microbiol."},{"key":"10.1006\/bbrc.2001.5983_RF15","doi-asserted-by":"crossref","first-page":"4757","DOI":"10.1021\/bi982443+","article-title":"Multistep denaturation of Borrelia burgdorferi OspA, a protein containing a single-layer beta-sheet","volume":"38","author":"Koide","year":"1999","journal-title":"Biochemistry"}],"container-title":["Biochemical and Biophysical Research Communications"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X01959832?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006291X01959832?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T15:35:06Z","timestamp":1680536106000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006291X01959832"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,11]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2001,11]]}},"alternative-id":["S0006291X01959832"],"URL":"https:\/\/doi.org\/10.1006\/bbrc.2001.5983","relation":{},"ISSN":["0006-291X"],"issn-type":[{"value":"0006-291X","type":"print"}],"subject":[],"published":{"date-parts":[[2001,11]]}}}