{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,12]],"date-time":"2025-09-12T18:40:23Z","timestamp":1757702423607},"reference-count":32,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[1997,4,1]],"date-time":"1997-04-01T00:00:00Z","timestamp":859852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochemical and Molecular Medicine"],"published-print":{"date-parts":[[1997,4]]},"DOI":"10.1006\/bmme.1997.2571","type":"journal-article","created":{"date-parts":[[2002,9,16]],"date-time":"2002-09-16T14:51:07Z","timestamp":1032187867000},"page":"161-168","source":"Crossref","is-referenced-by-count":12,"title":["Detection of Epstein\u2013Barr Viral DNA in Serum Using Rapid-Cycle PCR"],"prefix":"10.1006","volume":"60","author":[{"given":"C.Lars","family":"Mouritsen","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carl T.","family":"Wittwer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gudrun","family":"Reed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taiyaba M.","family":"Khan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas B.","family":"Martins","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Troy D.","family":"Jaskowski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine M.","family":"Litwin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Harry R.","family":"Hill","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1006\/bmme.1997.2571_MM972571C1","series-title":"The Epstein\u2013Barr Virus","author":"Epstein","year":"1979"},{"key":"10.1006\/bmme.1997.2571_MM972571C2","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1016\/S0140-6736(64)91524-7","article-title":"Virus particles in cultured lymphoblasts from Burkitt's lymphoma","volume":"1","author":"Epstein","year":"1964","journal-title":"Lancet"},{"key":"10.1006\/bmme.1997.2571_MM972571C3","series-title":"The Epstein\u2013Barr virus","article-title":"The virus as the etiologic agent of infectious mononucleosis","author":"Henle","year":"1979"},{"key":"10.1006\/bmme.1997.2571_MM972571C4","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1093\/infdis\/123.3.263","article-title":"Prospective studies of a group of Yale University freshmen. I. Occurrence of infectious mononucleosis","volume":"123","author":"Sawyer","year":"1971","journal-title":"J Infect Dis"},{"key":"10.1006\/bmme.1997.2571_MM972571C5","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1056\/NEJM197002122820704","article-title":"Prevalence, incidence and persistence of EB virus antibody in young adults","volume":"282","author":"Niederman","year":"1970","journal-title":"N Engl J Med"},{"key":"10.1006\/bmme.1997.2571_MM972571C6","series-title":"Principles and Practice of Infectious Diseases","first-page":"1172","author":"Schooley","year":"1990"},{"key":"10.1006\/bmme.1997.2571_MM972571C7","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1097\/00019606-199403010-00006","article-title":"Epstein\u2013Barr virus genomes in undifferentiated and squamous cell nasopharyngeal carcinomas in Italian patients","volume":"3","author":"Della Torre","year":"1994","journal-title":"Diag Molec Pathol"},{"key":"10.1006\/bmme.1997.2571_MM972571C8","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1038\/2281056a0","article-title":"EBV DNA in biopsies of Burkitt's tumors and anaplastic carcinoma of the nasopharynx","volume":"228","author":"Zur Hausen","year":"1980","journal-title":"Nature"},{"key":"10.1006\/bmme.1997.2571_MM972571C9","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.1056\/NEJM198512193132502","article-title":"Replication of Epstein\u2013Barr virus within the epithelial cells of oral \u201chairy\u201d leukoplakia and AIDS-associated lesion","volume":"313","author":"Greenspan","year":"1985","journal-title":"N Engl J Med"},{"key":"10.1006\/bmme.1997.2571_MM972571C10","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/0140-6736(93)92814-A","article-title":"Epstein\u2013Barr virus DNA in cerebrospinal fluid from patients with AIDS-related primary lymphoma of the central nervous system","volume":"342","author":"Cinque","year":"1993","journal-title":"Lancet"},{"key":"10.1006\/bmme.1997.2571_MM972571C11","series-title":"Manual of Clinical Microbiology","article-title":"Epstein\u2013Barr virus","author":"Lennette","year":"1985"},{"key":"10.1006\/bmme.1997.2571_MM972571C12","doi-asserted-by":"crossref","first-page":"2391","DOI":"10.1128\/JCM.25.12.2391-2394.1987","article-title":"Evaluation of latex-based heterophile antibody assay for the diagnosis of acute infectious mononucleosis","volume":"25","author":"Cook","year":"1987","journal-title":"J Clin Microbiol"},{"key":"10.1006\/bmme.1997.2571_MM972571C13","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1097\/00000441-193201000-00010","article-title":"The presence of heterophile antibodies in infectious mononucleosis","volume":"183","author":"Paul","year":"1932","journal-title":"Am J Med Sci"},{"key":"10.1006\/bmme.1997.2571_MM972571C14","doi-asserted-by":"crossref","first-page":"2305","DOI":"10.1128\/JCM.28.10.2305-2311.1990","article-title":"Serodiagnosis of infectious mononucleosis by using recombinant Epstein\u2013Barr virus antigens and enzyme-linked immunosorbent assay technology","volume":"28","author":"Gorgievski-Hrisoho","year":"1990","journal-title":"J Clin Microbiol"},{"key":"10.1006\/bmme.1997.2571_MM972571C15","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1093\/infdis\/146.6.734","article-title":"Detection of antibodies to Epstein\u2013Barr virus antigens by enzyme-linked immunosorbent assay","volume":"146","author":"Hopkins","year":"1982","journal-title":"J Infect Dis"},{"key":"10.1006\/bmme.1997.2571_MM972571C16","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/0022-1759(84)90093-0","article-title":"A sensitive enzyme-linked immunosorbent assay (ELISA) against the major EBV-associated antigens. I. Correlation between ELISA and immunofluorescence titers using purified antigens","volume":"67","author":"Luka","year":"1984","journal-title":"J Immunol Methods"},{"key":"10.1006\/bmme.1997.2571_MM972571C17","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/0890-8508(90)90030-4","article-title":"Oligonucleotides for polymerase chain reaction amplification and hybridization detection of Epstein\u2013Barr virus DNA in clinical specimens","volume":"4","author":"Ambinder","year":"1990","journal-title":"Mol Cell Probes"},{"key":"10.1006\/bmme.1997.2571_MM972571C18","doi-asserted-by":"crossref","first-page":"2187","DOI":"10.1128\/JCM.28.10.2187-2190.1990","article-title":"Detection of Epstein\u2013Barr virus by polymerase chain reaction","volume":"28","author":"Telenti","year":"1990","journal-title":"J Clin Microbiol"},{"key":"10.1006\/bmme.1997.2571_MM972571C19","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1128\/JCM.28.5.1026-1032.1990","article-title":"Detection of Epstein\u2013Barr virus genomes in normal human lacrimal glands","volume":"28","author":"Crouse","year":"1990","journal-title":"J Clin Microbiol"},{"key":"10.1006\/bmme.1997.2571_MM972571C20","first-page":"393","article-title":"Detection of Epstein\u2013Barr virus sequences in Hodgkin's disease by the polymerase chain reaction","volume":"139","author":"Wright","year":"1991","journal-title":"Am J Pathol"},{"key":"10.1006\/bmme.1997.2571_MM972571C21","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1097\/00007890-199502270-00014","article-title":"Viral and immunologic aspects of Epstein\u2013Barr virus infection in pediatric liver transplant recipients","volume":"59","author":"Martinez","year":"1995","journal-title":"Transplantation"},{"key":"10.1006\/bmme.1997.2571_MM972571C22","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1093\/infdis\/170.2.436","article-title":"Detection of cell-free Epstein\u2013Barr virus DNA in serum during acute infectious mononucleosis","volume":"170","author":"Gan","year":"1994","journal-title":"J Infect Dis"},{"key":"10.1006\/bmme.1997.2571_MM972571C23","doi-asserted-by":"crossref","first-page":"4353","DOI":"10.1093\/nar\/17.11.4353","article-title":"Automated polymerase chain reaction in capillary tubes with hot air","volume":"17","author":"Wittwer","year":"1989","journal-title":"Nucleic Acids Res"},{"key":"10.1006\/bmme.1997.2571_MM972571C24","series-title":"The Polymerase Chain Reaction","first-page":"174","article-title":"Rapid cycle DNA amplification","author":"Wittwer","year":"1994"},{"key":"10.1006\/bmme.1997.2571_MM972571C25","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1128\/JVI.44.1.286-294.1982","article-title":"Long internal repeat in Epstein\u2013Barr virus DNA","volume":"44","author":"Cheung","year":"1982","journal-title":"J Virol"},{"key":"10.1006\/bmme.1997.2571_MM972571C26","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1038\/310207a0","article-title":"DNA sequence and expression of the B95-8 Epstein\u2013Barr virus genome","volume":"310","author":"Baer","year":"1984","journal-title":"Nature"},{"key":"10.1006\/bmme.1997.2571_MM972571C27","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/0003-2697(90)90090-V","article-title":"Minimizing the time required for DNA amplification by efficient heat transfer to small samples","volume":"186","author":"Wittwer","year":"1990","journal-title":"Anal Biochem"},{"key":"10.1006\/bmme.1997.2571_MM972571C28","first-page":"76","article-title":"Rapid cycle DNA amplification: Time and temperature optimization","volume":"10","author":"Wittwer","year":"1991","journal-title":"BioTechniques"},{"key":"10.1006\/bmme.1997.2571_MM972571C29","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/S0140-6736(64)92345-1","article-title":"Cytology of Burkitt's tumor (African lymphoma)","volume":"1","author":"Pulvertaft","year":"1964","journal-title":"Lancet"},{"key":"10.1006\/bmme.1997.2571_MM972571C30","doi-asserted-by":"crossref","first-page":"2407","DOI":"10.1128\/JVI.64.5.2407-2410.1990","article-title":"The average number of molecules of Epstein\u2013Barr nuclear antigen 1 per cell does not correlate with the average number of Epstein\u2013Barr virus (EBV) molecules per cell among different clones of the EBV-immortalized cells","volume":"64","author":"Sternas","year":"1990","journal-title":"J Virol"},{"key":"10.1006\/bmme.1997.2571_MM972571C31","doi-asserted-by":"crossref","first-page":"5590","DOI":"10.1128\/JVI.66.9.5590-5593.1992","article-title":"Partial elimination of Epstein\u2013Barr virus plasmids from Burkitt's lymphoma cells by transfecting the BZLF1 gene","volume":"66","author":"Takada","year":"1992","journal-title":"J Virol"},{"key":"10.1006\/bmme.1997.2571_MM972571C32","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/0196-4399(93)90070-4","article-title":"Diagnosis of Epstein\u2013Barr virus infections in the clinical laboratory","volume":"15","author":"Thiele","year":"1993","journal-title":"Clin Microbiol Newsletter"}],"container-title":["Biochemical and Molecular Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1077315097925710?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1077315097925710?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,5,3]],"date-time":"2021-05-03T03:20:14Z","timestamp":1620012014000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1077315097925710"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,4]]},"references-count":32,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1997,4]]}},"alternative-id":["S1077315097925710"],"URL":"https:\/\/doi.org\/10.1006\/bmme.1997.2571","relation":{},"ISSN":["1077-3150"],"issn-type":[{"value":"1077-3150","type":"print"}],"subject":[],"published":{"date-parts":[[1997,4]]}}}