{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,18]],"date-time":"2026-01-18T20:55:21Z","timestamp":1768769721965,"version":"3.49.0"},"reference-count":0,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2013,1,2]],"date-time":"2013-01-02T00:00:00Z","timestamp":1357084800000},"content-version":"vor","delay-in-days":4964,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Cell Biology International"],"published-print":{"date-parts":[[1999,6]]},"abstract":"<jats:p>Levels of intracellular calcium, (Ca<jats:sup>2+<\/jats:sup>)<jats:sub>i<\/jats:sub>, from different stages of cell cycle of <jats:italic>Dictyostelium discoideum<\/jats:italic> were monitored using the fluorescent Ca<jats:sup>2+<\/jats:sup>\u2010sensitive dye, Indo 1. Combinations of Ca<jats:sup>2+<\/jats:sup>\u2010ionophore (A23187) and Ca<jats:sup>2+<\/jats:sup>\u2010chelator (EGTA) resulted in the inhibition of progression of cell cycle. This delay was caused due to block in G<jats:sub>2<\/jats:sub>\/M\u2192S phase transition of the cell cycle. Rescue of the cell cycle progression was made with 0.5m <jats:sc>m<\/jats:sc> of exogenous Ca<jats:sup>2+<\/jats:sup>. High (Ca<jats:sup>2+<\/jats:sup>)<jats:sub>i<\/jats:sub>levels overlapped with the S\u2010phase, of the cell cycle.<\/jats:p><jats:p>Results indicate that a high (Ca<jats:sup>2+<\/jats:sup>)<jats:sub>i<\/jats:sub>level during S\u2010phase is not required for cell cycle progression but for cell\u2010type choice mechanism at the onset of starvation, and these cells tend to follow the prestalk pathway.<\/jats:p>","DOI":"10.1006\/cbir.1999.0379","type":"journal-article","created":{"date-parts":[[2002,10,6]],"date-time":"2002-10-06T22:26:47Z","timestamp":1033943207000},"page":"399-405","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":11,"title":["CALCIUM LEVELS DURING CELL CYCLE CORRELATE WITH CELL FATE OF <i>DICTYOSTELIUM DISCOIDEUM<\/i>"],"prefix":"10.1002","volume":"23","author":[{"given":"Shweta","family":"Saran","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2013,1,2]]},"container-title":["Cell Biology International"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1006%2Fcbir.1999.0379","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1006\/cbir.1999.0379","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,28]],"date-time":"2023-10-28T22:01:18Z","timestamp":1698530478000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1006\/cbir.1999.0379"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,6]]},"references-count":0,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1999,6]]}},"alternative-id":["10.1006\/cbir.1999.0379"],"URL":"https:\/\/doi.org\/10.1006\/cbir.1999.0379","archive":["Portico"],"relation":{},"ISSN":["1065-6995","1095-8355"],"issn-type":[{"value":"1065-6995","type":"print"},{"value":"1095-8355","type":"electronic"}],"subject":[],"published":{"date-parts":[[1999,6]]},"assertion":[{"value":"2013-01-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}