{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:58:13Z","timestamp":1786978693477,"version":"build-2736575974"},"reference-count":22,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[1999,11,1]],"date-time":"1999-11-01T00:00:00Z","timestamp":941414400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Immunology"],"published-print":{"date-parts":[[1999,11]]},"DOI":"10.1006\/clim.1999.4764","type":"journal-article","created":{"date-parts":[[2002,9,16]],"date-time":"2002-09-16T11:45:11Z","timestamp":1032176711000},"page":"93-106","source":"Crossref","is-referenced-by-count":24,"title":["Anti-adhesion Molecule Therapy as an Interventional Strategy"],"prefix":"10.1006","volume":"93","author":[{"given":"C.M","family":"Lockwood","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.D","family":"Elliott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Brettman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G","family":"Hale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P","family":"Rebello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Frewin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Ringler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C","family":"Merrill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H","family":"Waldmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1006\/clim.1999.4764_RF1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1365-2249.1995.tb03594.x","article-title":"ANCA pathophysiology revisited","volume":"100","author":"Kallenberg","year":"1995","journal-title":"Clin. Exp. Immunol."},{"key":"10.1006\/clim.1999.4764_RF2","doi-asserted-by":"crossref","first-page":"2868","DOI":"10.1096\/fasebj.4.11.2199285","article-title":"Integrins and other cell adhesion molecules","volume":"4","author":"Albelda","year":"1990","journal-title":"FASEB J."},{"key":"10.1006\/clim.1999.4764_RF3","first-page":"L315","article-title":"Antibody against leukocyte integrin (CD18) prevents reperfusion-induced lung injury","volume":"259","author":"Horgan","year":"1990","journal-title":"Am. J. Physiol."},{"key":"10.1006\/clim.1999.4764_RF4","doi-asserted-by":"crossref","first-page":"2643","DOI":"10.1073\/pnas.87.7.2643","article-title":"Inhibition of leukocyte adherence by anti CD18 monoclonal antibody attenuates reperfusion injury in the rabbit ear","volume":"87","author":"Vedder","year":"1990","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1006\/clim.1999.4764_RF5","first-page":"206","article-title":"Inhibition of CD18-dependent neutrophil adherence reduces organ injury after hemmorrhagic shock in primates","volume":"108","author":"Mileski","year":"1990","journal-title":"Surgery"},{"key":"10.1006\/clim.1999.4764_RF6","doi-asserted-by":"crossref","first-page":"2234","DOI":"10.4049\/jimmunol.153.5.2234","article-title":"Ischaemia reperfusion injury in the rabbit ear is reduced by both immediate and delayed CD18 leukocyte adherence blockade","volume":"153","author":"Sharar","year":"1994","journal-title":"J. Immunol."},{"key":"10.1006\/clim.1999.4764_RF7","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1016\/0016-5085(91)90259-N","article-title":"A monoclonal antibody against the CD18 leukocyte adhesion molecule prevents indomethacin-induced gastric damage in the rabbit","volume":"100","author":"Wallace","year":"1991","journal-title":"Gastroenterology"},{"key":"10.1006\/clim.1999.4764_RF8","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1111\/j.1365-2249.1995.tb08363.x","article-title":"Anti CD11b\/CD18 antibodies reduce inflammation in acute colitis in rats","volume":"101","author":"Palmen","year":"1995","journal-title":"Clin. Exp. Immunol."},{"key":"10.1006\/clim.1999.4764_RF9","doi-asserted-by":"crossref","unstructured":"Rosen, H., Role of CR3 in induced myelmonocytic recruitment: Insights from in vivo monoclonal studies in the mouse. J. Leukocyte Biol.48, 465\u2013469.","DOI":"10.1002\/jlb.48.5.465"},{"key":"10.1006\/clim.1999.4764_RF10","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1084\/jem.166.6.1685","article-title":"Monoclonal antibodies to the murine type 3 complement receptor inhibits adhesion of myelmonocytic cell in vitro and inflammatory cell recruitment in vivo","volume":"166","author":"Rosen","year":"1987","journal-title":"J. Exp. Med."},{"key":"10.1006\/clim.1999.4764_RF11","first-page":"53","article-title":"Intervention in experimental anti-MPO associated crescentic glomerular nephritis by monoclonal antibodies against adhesion molecules","volume":"101","author":"Muller","year":"1995","journal-title":"Clin. Exp. Immunol."},{"key":"10.1006\/clim.1999.4764_RF12","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1046\/j.1365-2567.1996.d01-695.x","article-title":"Treatment of established adjuvant arthritis in rats with monoclonal antibody to CD18 and very late activation antigen-4 integrins suppresses neutrophil and T0-lymphocyte migration to the joints and improved clinical disease","volume":"88","author":"Issekutz","year":"1996","journal-title":"Immunology"},{"key":"10.1006\/clim.1999.4764_RF13","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1177\/135245859700200601","article-title":"Resolution of CNS lesions following treatment of experimental allergic encephalomyelitis in macaques with monoclonal antibody to the CD18 leukocyte integrin","volume":"2","author":"Rose","year":"1997","journal-title":"Multiple Sclerosis"},{"key":"10.1006\/clim.1999.4764_RF14","doi-asserted-by":"crossref","first-page":"2296","DOI":"10.4049\/jimmunol.151.4.2296","article-title":"A humanised CD18 antibody can block function without cell destruction","volume":"151","author":"Sims","year":"1993","journal-title":"J. Immunol."},{"key":"10.1006\/clim.1999.4764_RF15","first-page":"509","article-title":"Management of systemic vasculitis: Contribution of scintigraphic imaging to the evaluation of disease activity and classification","volume":"88","author":"Reuter","year":"1995","journal-title":"Q. J. Med."},{"key":"10.1006\/clim.1999.4764_RF16","doi-asserted-by":"crossref","first-page":"1620","DOI":"10.1016\/0140-6736(93)90759-A","article-title":"Humanised monoclonal antibody therapy for intractable systemic vasculitis","volume":"341","author":"Lockwood","year":"1993","journal-title":"Lancet"},{"key":"10.1006\/clim.1999.4764_RF17","series-title":"Current Protocols in Immunology","author":"Shevach","year":"1991"},{"key":"10.1006\/clim.1999.4764_RF18","doi-asserted-by":"crossref","first-page":"2185","DOI":"10.1093\/ndt\/13.9.2185","article-title":"Polymorphonuclear neutrophils in acute renal failure: new insight","volume":"13","author":"Caramelo","year":"1998","journal-title":"Nephrol. Dial. Transplant"},{"key":"10.1006\/clim.1999.4764_RF19","doi-asserted-by":"crossref","first-page":"1398","DOI":"10.1056\/NEJM199905063401804","article-title":"Infliximab for the treatment of fistulaas in patients with Crohn's disease","volume":"340","author":"Present","year":"1999","journal-title":"N. Engl. J. Med."},{"key":"10.1006\/clim.1999.4764_RF20","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1083\/jcb.109.3.1341","article-title":"Cytokine-induced respiratory burst of human neutrophils: dependence on extracellular matrix proteins and CD11\/CD18 integrins","volume":"109","author":"Nathan","year":"1989","journal-title":"J. Cell. Biol."},{"key":"10.1006\/clim.1999.4764_RF21","doi-asserted-by":"crossref","first-page":"2702","DOI":"10.4049\/jimmunol.144.7.2702","article-title":"Mac-1 (CD11b\/CD18) mediates adherence-dependant hydrogen peroxide production by human and canine neutrophils","volume":"144","author":"Shappell","year":"1990","journal-title":"J. Immunol."},{"key":"10.1006\/clim.1999.4764_RF22","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1097\/00002281-199701000-00004","article-title":"Cell adhesion molecules in vasculitis","volume":"9","author":"Tervaert","year":"1997","journal-title":"Curr. Opin. Rheumatol."}],"container-title":["Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521661699947642?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521661699947642?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T20:00:54Z","timestamp":1680552054000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1521661699947642"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,11]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1999,11]]}},"alternative-id":["S1521661699947642"],"URL":"https:\/\/doi.org\/10.1006\/clim.1999.4764","relation":{},"ISSN":["1521-6616"],"issn-type":[{"value":"1521-6616","type":"print"}],"subject":[],"published":{"date-parts":[[1999,11]]}}}