{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T05:47:32Z","timestamp":1784699252293,"version":"3.55.0"},"reference-count":21,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2000,9,1]],"date-time":"2000-09-01T00:00:00Z","timestamp":967766400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Clinical Immunology"],"published-print":{"date-parts":[[2000,9]]},"DOI":"10.1006\/clim.2000.4884","type":"journal-article","created":{"date-parts":[[2002,9,16]],"date-time":"2002-09-16T11:45:11Z","timestamp":1032176711000},"page":"264-268","source":"Crossref","is-referenced-by-count":16,"title":["Duffy Phenotype Does Not Influence the Clinical Severity of Sickle Cell Disease"],"prefix":"10.1006","volume":"96","author":[{"given":"J.B.","family":"Schnog","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.O.","family":"Keli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.A.","family":"Pieters","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.A.","family":"Rojer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.J.","family":"Duits","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1006\/clim.2000.4884_RF1","doi-asserted-by":"crossref","first-page":"3077","DOI":"10.1182\/blood.V89.9.3077","article-title":"From malaria to chemokine receptor: The emerging physiologic role of the Duffy blood group antigen","volume":"89","author":"Hadley","year":"1997","journal-title":"Blood"},{"key":"10.1006\/clim.2000.4884_RF2","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1111\/j.1423-0410.1998.tb05397.x","article-title":"Insights into the structure and function of membrane polypeptides carrying blood group antigens","volume":"74","author":"Cartron","year":"1998","journal-title":"Vox Sanguines"},{"key":"10.1006\/clim.2000.4884_RF3","doi-asserted-by":"crossref","first-page":"1362","DOI":"10.1172\/JCI115442","article-title":"Red blood cells are a sink for interleukin 8, a leukocyte chemotactin","volume":"88","author":"Darbonne","year":"1991","journal-title":"J. Clin. Invest."},{"key":"10.1006\/clim.2000.4884_RF4","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1111\/j.1600-0609.1998.tb01092.x","article-title":"Elevated IL-8 levels during sickle cell crisis","volume":"61","author":"Duits","year":"1998","journal-title":"Eur. J. Haematol."},{"key":"10.1006\/clim.2000.4884_RF5","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1056\/NEJM198005013021803","article-title":"Erythrocyte adherence to endothelium in sickle cell anemia: A possible determinant of disease severity","volume":"302","author":"Hebbel","year":"1980","journal-title":"N. Engl. J. Med."},{"key":"10.1006\/clim.2000.4884_RF6","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1111\/j.1365-2141.1992.tb02997.x","article-title":"Red blood cells from patients with sickle cell disease exhibit increased adherence to cultured endothelium pretreated with tumour necrosis factor","volume":"81","author":"Vordemeier","year":"1992","journal-title":"Br. J. Haematol."},{"key":"10.1006\/clim.2000.4884_RF7","first-page":"1864","article-title":"Screening cord blood for hemoglobinopathies and thalassemia by HPLC","volume":"38","author":"Van der Dijs","year":"1992","journal-title":"Clin. Chem."},{"key":"10.1006\/clim.2000.4884_RF8","series-title":"Sickle Cell Disease","author":"Serjeant","year":"1985"},{"key":"10.1006\/clim.2000.4884_RF9","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1002\/(SICI)1096-8652(199805)58:1<61::AID-AJH11>3.0.CO;2-8","article-title":"New concepts in assessing sickle cell disease severity","volume":"58","author":"Schnog","year":"1998","journal-title":"Am. J. Hematol."},{"key":"10.1006\/clim.2000.4884_RF10","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1056\/NEJM199107043250103","article-title":"Pain in sickle cell disease: Rates and risk factors","volume":"325","author":"Platt","year":"1991","journal-title":"N. Engl. J. Med."},{"key":"10.1006\/clim.2000.4884_RF11","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.1182\/blood.V89.5.1787","article-title":"Acute chest syndrome in sickle cell disease: Clinical presentation and course","volume":"89","author":"Vichinski","year":"1997","journal-title":"Blood"},{"key":"10.1006\/clim.2000.4884_RF12","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1016\/S0140-6736(96)07524-1","article-title":"Chemokines: Leukocyte recruitment and activation cytokines","volume":"349","author":"Adams","year":"1997","journal-title":"Lancet"},{"key":"10.1006\/clim.2000.4884_RF13","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1084\/jem.181.4.1311","article-title":"The Duffy antigen\/receptor for chemokines (DARC) is expressed in endothelial cells of Duffy negative individuals who lack the erythrocyte receptor","volume":"181","author":"Peiper","year":"1995","journal-title":"J. Exp. Med."},{"key":"10.1006\/clim.2000.4884_RF14","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/S0092-8674(00)80422-5","article-title":"Transcytosis and surface presentation of IL-8 by venular endothelial cells","volume":"91","author":"Middleton","year":"1997","journal-title":"Cell"},{"key":"10.1006\/clim.2000.4884_RF15","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1182\/blood.V84.1.44.44","article-title":"Functional and biochemical analysis of the cloned duffy antigen: Identity with the red blood cell chemokine receptor","volume":"84","author":"Neote","year":"1994","journal-title":"Blood"},{"key":"10.1006\/clim.2000.4884_RF16","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1046\/j.1523-1755.1999.00385.x","article-title":"Up-regulation of Duffy antigen receptor expression in children with renal disease","volume":"55","author":"Lui","year":"1999","journal-title":"Kidney Int."},{"key":"10.1006\/clim.2000.4884_RF17","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1002\/jlb.66.3.411","article-title":"Neutrophil activation in sickle cell disease","volume":"66","author":"Lard","year":"1999","journal-title":"J. Leukocyte Biol."},{"key":"10.1006\/clim.2000.4884_RF18","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1002\/(SICI)1096-8652(199703)54:3<183::AID-AJH2>3.0.CO;2-S","article-title":"Assessment of painful episode frequency in sickle-cell disease","volume":"54","author":"Westerman","year":"1997","journal-title":"Am. J. Hematol."},{"key":"10.1006\/clim.2000.4884_RF19","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1111\/j.1365-2141.1995.tb05202.x","article-title":"Mutations in the erythrocyte chemokine receptor (Duffy) gene: The molecular basis of the Fy\/Fy antigens and identification of a deletion in the Duffy gene of an apparently healthy individual with the Fy(a\u2212-b\u2212-) phenotype","volume":"90","author":"Mallison","year":"1995","journal-title":"Br. J. Haematol."},{"key":"10.1006\/clim.2000.4884_RF20","doi-asserted-by":"crossref","first-page":"2237","DOI":"10.1182\/blood.V92.7.2237","article-title":"A novel mutation in the coding sequence of the FY*B allele of the Duffy chemokine receptor gene is associated with an altered erythrocyte phenotype","volume":"92","author":"Parasol","year":"1998","journal-title":"Blood"},{"key":"10.1006\/clim.2000.4884_RF21","doi-asserted-by":"crossref","first-page":"2147","DOI":"10.1182\/blood.V92.6.2147","article-title":"Arg89Cys substitution results in very low membrane expression of the Duffy antigen\/receptor for chemokines in Fyx individuals","volume":"92","author":"Tournamille","year":"1998","journal-title":"Blood"}],"container-title":["Clinical Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521661600948848?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1521661600948848?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,12,16]],"date-time":"2019-12-16T03:15:02Z","timestamp":1576466102000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1521661600948848"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,9]]},"references-count":21,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2000,9]]}},"alternative-id":["S1521661600948848"],"URL":"https:\/\/doi.org\/10.1006\/clim.2000.4884","relation":{},"ISSN":["1521-6616"],"issn-type":[{"value":"1521-6616","type":"print"}],"subject":[],"published":{"date-parts":[[2000,9]]}}}