{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T12:58:58Z","timestamp":1790427538241,"version":"4.1.0"},"reference-count":60,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[1998,3,1]],"date-time":"1998-03-01T00:00:00Z","timestamp":888710400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[1998,3,1]],"date-time":"1998-03-01T00:00:00Z","timestamp":888710400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Clinical Immunology and Immunopathology"],"published-print":{"date-parts":[[1998,3]]},"DOI":"10.1006\/clin.1997.4481","type":"journal-article","created":{"date-parts":[[2002,9,16]],"date-time":"2002-09-16T11:45:11Z","timestamp":1032176711000},"page":"271-279","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":40,"title":["Influence of Microbial Stimulation on Hypergammaglobulinemia and Autoantibody Production in Pristane-Induced Lupus"],"prefix":"10.1006","volume":"86","author":[{"given":"Kimberly J.","family":"Hamilton","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minoru","family":"Satoh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Swartz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanno B.","family":"Richards","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Westley H.","family":"Reeves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1006\/clin.1997.4481_II974481RF1","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/0005-2760(67)90084-7","article-title":"The occurrence of pristane and phytane in man and animals","volume":"144","author":"Avigan","year":"1967","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1006\/clin.1997.4481_II974481RF2","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1080\/02652039309374140","article-title":"Migration of mineral hydrocarbons into foods. 2. Polystyrene, ABS, and waxed paperboard containers for dairy products","volume":"10","author":"Castle","year":"1993","journal-title":"Food Additives Contaminants"},{"key":"10.1006\/clin.1997.4481_II974481RF3","first-page":"402","article-title":"Mineral oil in human tissues. I. Detection of saturated hydrocarbons using thin-layer chromatography","volume":"118","author":"Boitnott","year":"1966","journal-title":"Bull. Johns Hopkins Hosp."},{"key":"10.1006\/clin.1997.4481_II974481RF4","first-page":"283","article-title":"Mineral oil lipogramulomata in liver and spleen: A study of 465 autopsies","volume":"109","author":"Wanless","year":"1985","journal-title":"Arch. Pathol. Lab. Med."},{"key":"10.1006\/clin.1997.4481_II974481RF5","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1177\/019262339502300104","article-title":"Comparative 90-day feeding study with low-viscosity white mineral oil in Fischer-344 and Sprague\u2013Dawley-derived CRL:CD rats","volume":"23","author":"Firriolo","year":"1995","journal-title":"Toxicol. Pathol."},{"key":"10.1006\/clin.1997.4481_II974481RF6","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1038\/1931086a0","article-title":"Induction of plasma-cell neoplasms in strain BALB\/c mice with mineral oil and mineral oil adjuvants","volume":"193","author":"Potter","year":"1962","journal-title":"Nature"},{"key":"10.1006\/clin.1997.4481_II974481RF7","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1038\/222994a0","article-title":"Induction of plasma cell tumours in BALB\/c mice with 2,6,10,14-tetramethylpentadecane (pristane)","volume":"222","author":"Anderson","year":"1969","journal-title":"Nature"},{"key":"10.1006\/clin.1997.4481_II974481RF8","first-page":"497","article-title":"Histology of developing plasma cell neoplasia induced by mineral oil in BALB\/c mice","volume":"33","author":"Potter","year":"1964","journal-title":"J. Natl. Cancer Inst."},{"key":"10.1006\/clin.1997.4481_II974481RF9","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1084\/jem.161.5.996","article-title":"Inhibition of plasmacytoma development in BALB\/c mice by indomethacin","volume":"161","author":"Potter","year":"1985","journal-title":"J. Exp. Med."},{"key":"10.1006\/clin.1997.4481_II974481RF10","first-page":"670","article-title":"Absorption of liquid petrolatum (\u201cmineral oil\u201d) from the intestine","volume":"31","author":"Stryker","year":"1941","journal-title":"Arch. Pathol."},{"key":"10.1006\/clin.1997.4481_II974481RF11","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1093\/ajcp\/78.1.35","article-title":"Lipogranulomas in non-fatty human livers: A mineral oil induced environmental disease","volume":"78","author":"Dincsoy","year":"1982","journal-title":"Am. J. Clin. Pathol."},{"key":"10.1006\/clin.1997.4481_II974481RF12","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1016\/S0046-8177(84)80162-8","article-title":"Follicular (mineral oil) lipidosis. I. Epidemiologic studies of involvement of the spleen","volume":"15","author":"Cruickshank","year":"1984","journal-title":"Hum. Pathol."},{"key":"10.1006\/clin.1997.4481_II974481RF13","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1001\/archinte.1994.00420060122013","article-title":"Exogenous lipoid pneumonia","volume":"154","author":"Spickard","year":"1994","journal-title":"Arch. Intern. Med."},{"key":"10.1006\/clin.1997.4481_II974481RF14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/art.1780270101","article-title":"Clinical spectrum of connective tissue disease after cosmetic surgery. Observations on eighteen patients and a review of the Japanese literature","volume":"27","author":"Kumagai","year":"1984","journal-title":"Arthritis Rheum."},{"key":"10.1006\/clin.1997.4481_II974481RF15","doi-asserted-by":"crossref","first-page":"2341","DOI":"10.1084\/jem.180.6.2341","article-title":"Induction of lupus-associated autoantibodies in BALB\/c mice by intraperitoneal injection of pristane","volume":"180","author":"Satoh","year":"1994","journal-title":"J. Exp. Med."},{"key":"10.1006\/clin.1997.4481_II974481RF16","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/0022-1759(95)00022-3","article-title":"Pristane induces high titers of anti-Su and anti-nRNP\/Sm autoantibodies in BALB\/c mice. Quantitation by antigen capture ELISAs based on monospecific human autoimmune sera","volume":"182","author":"Satoh","year":"1995","journal-title":"J. Immunol. Methods"},{"key":"10.1006\/clin.1997.4481_II974481RF17","doi-asserted-by":"crossref","first-page":"10934","DOI":"10.1073\/pnas.92.24.10934","article-title":"Antinuclear antibody production and immune complex glomerulonephritis in BALB\/c mice treated with pristane","volume":"92","author":"Satoh","year":"1995","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1006\/clin.1997.4481_II974481RF18","doi-asserted-by":"crossref","first-page":"1022","DOI":"10.1002\/anr.1780320812","article-title":"Pristane-induced arthritis. The immunologic and genetic features of an experimental murine model of autoimmune disease","volume":"32","author":"Wooley","year":"1989","journal-title":"Arthritis Rheum."},{"key":"10.1006\/clin.1997.4481_II974481RF19","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1097\/00002281-199609000-00003","article-title":"Autoantibodies in systemic lupus erythematosus","volume":"8","author":"Alarcon-Segovia","year":"1996","journal-title":"Curr. Opin. Rheumatol."},{"key":"10.1006\/clin.1997.4481_II974481RF20","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/978-1-4615-2427-4_15","article-title":"Natural autoantibodies","volume":"347","author":"Chai","year":"1994","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1006\/clin.1997.4481_II974481RF21","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/0167-5699(88)91333-3","article-title":"Autoimmunity: Polyclonal activation or antigen induction","volume":"9","author":"Dziarski","year":"1988","journal-title":"Immunol. Today"},{"key":"10.1006\/clin.1997.4481_II974481RF22","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/0896-8411(89)90270-9","article-title":"Natural autoantibodies in nude and normal outbred (Swiss) and inbred (BALB\/c) mice","volume":"2","author":"Lymberi","year":"1989","journal-title":"J. Autoimmun."},{"key":"10.1006\/clin.1997.4481_II974481RF23","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1002\/art.1780200312","article-title":"Increased spontaneous activity of antibody-forming cells in the peripheral blood of patients with active SLE","volume":"20","author":"Budman","year":"1977","journal-title":"Arthritis Rheum."},{"key":"10.1006\/clin.1997.4481_II974481RF24","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1002\/art.1780310112","article-title":"B cell hyperactivity and its relation to distinct clinical features and the degree of disease activity in patients with systemic lupus erythematosus","volume":"31","author":"Sakane","year":"1988","journal-title":"Arthritis Rheum."},{"key":"10.1006\/clin.1997.4481_II974481RF25","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1084\/jem.165.6.1755","article-title":"Systemic autoimmune disease arises from polyclonal B cell activation","volume":"165","author":"Klinman","year":"1987","journal-title":"J. Exp. Med."},{"key":"10.1006\/clin.1997.4481_II974481RF26","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1172\/JCI114831","article-title":"Polyclonal B cell activation in lupus-prone mice precedes and predicts the development of autoimmune disease","volume":"86","author":"Klinman","year":"1990","journal-title":"J. Clin. Invest."},{"key":"10.1006\/clin.1997.4481_II974481RF27","doi-asserted-by":"crossref","first-page":"2213","DOI":"10.4049\/jimmunol.121.6.2213","article-title":"Increased spontaneous polyclonal activation of B lymphocytes in mice with spontaneous autoimmune disease","volume":"121","author":"Izui","year":"1978","journal-title":"J. Immunol."},{"key":"10.1006\/clin.1997.4481_II974481RF28","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1084\/jem.171.1.265","article-title":"Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation","volume":"171","author":"Shlomchik","year":"1990","journal-title":"J. Exp. Med."},{"key":"10.1006\/clin.1997.4481_II974481RF29","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1084\/jem.161.2.378","article-title":"Successful treatment of autoimmunity in NZB\/NZW F1 mice with monoclonal antibody to L3T4","volume":"161","author":"Wofsy","year":"1985","journal-title":"J. Exp. Med."},{"key":"10.1006\/clin.1997.4481_II974481RF30","doi-asserted-by":"crossref","first-page":"1713","DOI":"10.1084\/jem.167.5.1713","article-title":"The contribution of L3T4+ T cells to lymphoproliferation and autoantibody production in MRL\u2013lpr\/lpr mice","volume":"167","author":"Santoro","year":"1988","journal-title":"J. Exp. Med."},{"key":"10.1006\/clin.1997.4481_II974481RF31","first-page":"98","article-title":"Standard curve fitting in immunodiagnostics: A primer","volume":"8","author":"Maciel","year":"1985","journal-title":"J. Clin. Immunoassay"},{"key":"10.1006\/clin.1997.4481_II974481RF32","series-title":"Dubois\u2019 Lupus Erythematosus","article-title":"Animal models of systemic lupus erythematosus","author":"Hahn","year":"1996"},{"key":"10.1006\/clin.1997.4481_II974481RF33","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/S0065-2776(08)60342-9","article-title":"Murine models of systemic lupus erythematosus","volume":"37","author":"Theofilopoulos","year":"1985","journal-title":"Adv. Immunol."},{"key":"10.1006\/clin.1997.4481_II974481RF34","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/0092-8674(93)80067-O","article-title":"Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene","volume":"75","author":"Sadlack","year":"1993","journal-title":"Cell"},{"key":"10.1006\/clin.1997.4481_II974481RF35","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/0092-8674(93)80068-P","article-title":"Interleukin-10-deficient mice develop chronic enterocolitis","volume":"75","author":"K\u00fchn","year":"1993","journal-title":"Cell"},{"key":"10.1006\/clin.1997.4481_II974481RF36","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1084\/jem.185.4.791","article-title":"Effects of breeding environments on generation and activation of autoreactive B-1 cells in anti-red blood cell autoantibody transgenic mice","volume":"185","author":"Murakami","year":"1997","journal-title":"J. Exp. Med."},{"key":"10.1006\/clin.1997.4481_II974481RF37","doi-asserted-by":"crossref","first-page":"506","DOI":"10.4049\/jimmunol.144.2.506","article-title":"Development of the autoimmune B cell repertoire in MRL\u2013lpr\/lpr mice","volume":"144","author":"Klinman","year":"1990","journal-title":"J. Immunol."},{"key":"10.1006\/clin.1997.4481_II974481RF38","doi-asserted-by":"crossref","first-page":"3200","DOI":"10.4049\/jimmunol.157.7.3200","article-title":"Autoantibodies to ribosomal P antigens with immune complex glomerulonephritis in SJL mice treated with pristane","volume":"157","author":"Satoh","year":"1996","journal-title":"J. Immunol."},{"key":"10.1006\/clin.1997.4481_II974481RF39","doi-asserted-by":"crossref","first-page":"1460","DOI":"10.1056\/NEJM198806023182209","article-title":"Drug-related lupus","volume":"318","author":"Hess","year":"1988","journal-title":"N. Engl. J. Med."},{"key":"10.1006\/clin.1997.4481_II974481RF40","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1172\/JCI115353","article-title":"Drug-induced anti-histone autoantibodies display two patterns of reactivity with substructures of chromatin","volume":"88","author":"Burlingame","year":"1991","journal-title":"J. Clin. Invest."},{"key":"10.1006\/clin.1997.4481_II974481RF41","first-page":"79","article-title":"Glomerulonephritis in procainamide induced lupus erythematosus: Report of a case and review of the literature","volume":"2","author":"Foucar","year":"1979","journal-title":"J. Clin. Lab. Immunol."},{"key":"10.1006\/clin.1997.4481_II974481RF42","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1006\/cimm.1993.1014","article-title":"Pristane induces an indomethacin inhibitable inflammatory influx of CD4+T cells and IFN-\u03b3 production in plasmacytoma-susceptible BALB\/cAnPt mice","volume":"146","author":"McDonald","year":"1993","journal-title":"Cell. Immunol."},{"key":"10.1006\/clin.1997.4481_II974481RF43","doi-asserted-by":"crossref","first-page":"3632","DOI":"10.4049\/jimmunol.147.10.3632","article-title":"Specific pathogen-free BALB\/cAn mice are refractory to plasmacytoma induction by pristane","volume":"147","author":"Byrd","year":"1991","journal-title":"J. Immunol."},{"key":"10.1006\/clin.1997.4481_II974481RF44","doi-asserted-by":"crossref","first-page":"6509","DOI":"10.4049\/jimmunol.151.11.6509","article-title":"Polyclonal B cell activation arises from different mechanisms in lupus-prone (NZB \u00d7 NZW)F1 and MRL\/MpJ\u2013lpr\/lprmice","volume":"151","author":"Merino","year":"1993","journal-title":"J. Immunol."},{"key":"10.1006\/clin.1997.4481_II974481RF45","first-page":"114","article-title":"Thymus-independent B-cell induction and paralysis","volume":"21","author":"Coutinho","year":"1975","journal-title":"Adv. Immunol."},{"key":"10.1006\/clin.1997.4481_II974481RF46","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/0952-7915(95)80109-X","article-title":"T cell independent antigens","volume":"7","author":"Mond","year":"1995","journal-title":"Curr. Opin. Immunol."},{"key":"10.1006\/clin.1997.4481_II974481RF47","doi-asserted-by":"crossref","first-page":"2789","DOI":"10.4049\/jimmunol.131.6.2789","article-title":"Studies of congenic MRL\u2013lpr\/lpr.xidmice","volume":"131","author":"Steinberg","year":"1983","journal-title":"J. Immunol."},{"key":"10.1006\/clin.1997.4481_II974481RF48","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1084\/jem.176.5.1343","article-title":"Development of autoimmune disease in SCID mice populated with long-term \u201cin vitro\u201d proliferating (NZB \u00d7 NZW)F1 pre-B cells","volume":"176","author":"Reininger","year":"1992","journal-title":"J. Exp. Med."},{"key":"10.1006\/clin.1997.4481_II974481RF49","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1016\/0896-8411(92)90185-S","article-title":"Bacterial agents protect against autoimmune disease. I. Mice pre-exposed toBordetella pertussisorMycobacterium tuberculosisare highly refractory to induction of experimental autoimmune encephalomyelitis","volume":"5","author":"Lehmann","year":"1992","journal-title":"J. Autoimmun."},{"key":"10.1006\/clin.1997.4481_II974481RF50","doi-asserted-by":"crossref","first-page":"35","DOI":"10.3109\/08916939108994706","article-title":"Modulation of pristane-induced arthritis by mycobacterial antigens","volume":"11","author":"Thompson","year":"1991","journal-title":"Autoimmunity"},{"key":"10.1006\/clin.1997.4481_II974481RF51","doi-asserted-by":"crossref","first-page":"259","DOI":"10.2337\/diab.40.2.259","article-title":"Influence of environmental viral agents on frequency and tempo of diabetes mellitus in BB\/Wor rats","volume":"40","author":"Like","year":"1991","journal-title":"Diabetes"},{"key":"10.1006\/clin.1997.4481_II974481RF52","first-page":"288","article-title":"The influence of the normal microbial flora on the susceptibility of rats to experimental autoimmune thyroiditis","volume":"72","author":"Penhale","year":"1988","journal-title":"Clin. Exp. Immunol."},{"key":"10.1006\/clin.1997.4481_II974481RF53","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1084\/jem.180.1.111","article-title":"Oral administration of lipopolysaccharides activates B-1 cells in the peritoneal cavity and lamina propria of the gut and induces autoimmune symptoms in an autoantibody transgenic mouse","volume":"180","author":"Murakami","year":"1994","journal-title":"J. Exp. Med."},{"key":"10.1006\/clin.1997.4481_II974481RF54","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/0165-2478(93)90057-9","article-title":"Susceptibility to pristane-induced arthritis is altered with changes in bowel flora","volume":"36","author":"Thompson","year":"1993","journal-title":"Immunol. Lett."},{"key":"10.1006\/clin.1997.4481_II974481RF55","doi-asserted-by":"crossref","first-page":"2257","DOI":"10.1073\/pnas.93.6.2257","article-title":"Viruses, cytokines, antigens, and autoimmunity","volume":"93","author":"Gianani","year":"1996","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1006\/clin.1997.4481_II974481RF56","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1182\/blood.V80.1.194.194","article-title":"Elevation of interleukin-6 in response to a chronic inflammatory stimulus in mice: Inhibition by indomethacin","volume":"80","author":"Shacter","year":"1992","journal-title":"Blood"},{"key":"10.1006\/clin.1997.4481_II974481RF57","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1073\/pnas.84.1.228","article-title":"Human B-cell differentiation factor defined by an anti-peptide antibody and its possible role in autoantibody production","volume":"84","author":"Hirano","year":"1987","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1006\/clin.1997.4481_II974481RF58","doi-asserted-by":"crossref","first-page":"7547","DOI":"10.1073\/pnas.86.19.7547","article-title":"IgG1 plasmacytosis in interleukin 6 transgenic mice","volume":"86","author":"Suematsu","year":"1989","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1006\/clin.1997.4481_II974481RF59","doi-asserted-by":"crossref","first-page":"3949","DOI":"10.4049\/jimmunol.143.12.3949","article-title":"Involvement of IL-6 in mesangial proliferative glomerulonephritis","volume":"143","author":"Horii","year":"1989","journal-title":"J. Immunol."},{"key":"10.1006\/clin.1997.4481_II974481RF60","doi-asserted-by":"crossref","first-page":"6525","DOI":"10.4049\/jimmunol.151.11.6525","article-title":"Constitutive expression of IL-6 receptors and their role in the excessive B cell function in patients with systemic lupus erythematosus","volume":"151","author":"Nagafuchi","year":"1993","journal-title":"J. Immunol."}],"container-title":["Clinical Immunology and Immunopathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090122997944810?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090122997944810?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T01:09:33Z","timestamp":1758762573000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0090122997944810"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,3]]},"references-count":60,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1998,3]]}},"alternative-id":["S0090122997944810"],"URL":"https:\/\/doi.org\/10.1006\/clin.1997.4481","relation":{},"ISSN":["0090-1229"],"issn-type":[{"value":"0090-1229","type":"print"}],"subject":[],"published":{"date-parts":[[1998,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Influence of Microbial Stimulation on Hypergammaglobulinemia and Autoantibody Production in Pristane-Induced Lupus","name":"articletitle","label":"Article Title"},{"value":"Clinical Immunology and Immunopathology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1006\/clin.1997.4481","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1998 Academic Press. All rights reserved.","name":"copyright","label":"Copyright"}]}}