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Clin. Invest."},{"key":"10.1006\/clin.1998.4526_II984526RF81","first-page":"355","article-title":"Analysis of cytokine gene expression in Graves\u2019 disease and multinodular goiter","volume":"79","author":"Watson","year":"1994","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1006\/clin.1998.4526_II984526RF82","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1210\/mend-1-12-913","article-title":"Thyrotropin stimulation of cultured thyroid cells increases steady state levels of the messenger ribonucleic acid for thyroid peroxidase","volume":"1","author":"Chazenbalk","year":"1987","journal-title":"Mol. 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