{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T01:44:05Z","timestamp":1779241445279,"version":"3.51.4"},"reference-count":36,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[1999,12,1]],"date-time":"1999-12-01T00:00:00Z","timestamp":944006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cytokine"],"published-print":{"date-parts":[[1999,12]]},"DOI":"10.1006\/cyto.1999.0503","type":"journal-article","created":{"date-parts":[[2002,10,7]],"date-time":"2002-10-07T14:19:07Z","timestamp":1034000347000},"page":"1046-1056","source":"Crossref","is-referenced-by-count":14,"title":["IMMUNE COMPLEXES, BUT NOT STREPTOCOCCAL CELL WALLS OR ZYMOSAN, CAUSE CHRONIC ARTHRITIS IN MOUSE STRAINS SUSCEPTIBLE FOR COLLAGEN TYPE II AUTO-IMMUNE ARTHRITIS"],"prefix":"10.1006","volume":"11","author":[{"given":"Arjen B","family":"Blom","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter L.E.M","family":"van Lent","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Astrid E.M","family":"Holthuysen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wim B","family":"van den Berg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1006\/cyto.1999.0503_RF1","first-page":"689","article-title":"Gammaglobulin complexes in synovial fluid of patients with rheumatoid arthritis. Partial characterisation and relationship to lowered complement levels","volume":"6","author":"Winchester","year":"1970","journal-title":"Clin Exp Immunol"},{"key":"10.1006\/cyto.1999.0503_RF2","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1002\/art.1780180603","article-title":"Identification of immunoglobulins and complement in rheumatoid articular collagenous tissues","volume":"18","author":"Cooke","year":"1975","journal-title":"Arthritis Rheum"},{"key":"10.1006\/cyto.1999.0503_RF3","first-page":"235","article-title":"Deleterious interactions of immune complexes in cartilage of experimental immune arthritis","volume":"183","author":"Cooke","year":"1985","journal-title":"Clin Orthop"},{"key":"10.1006\/cyto.1999.0503_RF4","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1002\/art.1780221205","article-title":"Collagen-induced arthritis in rats. Evaluation of early immunological events","volume":"22","author":"Stuart","year":"1979","journal-title":"Arthritis Rheum"},{"key":"10.1006\/cyto.1999.0503_RF5","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1084\/jem.135.2.323","article-title":"The pathogenesis of chronic inflammation in experimental antigen-induced arthritis. II. Preferential localization of antigen-antibody complexes to collagenous tissues","volume":"135","author":"Cooke","year":"1972","journal-title":"J Exp Med"},{"key":"10.1006\/cyto.1999.0503_RF6","first-page":"224","article-title":"Electrical charge of the antigen determines its localization in the mouse knee joint. Deep penetration of cationic BSA in hyaline articular cartilage","volume":"121","author":"van den Berg","year":"1985","journal-title":"Am J Pathol"},{"key":"10.1006\/cyto.1999.0503_RF7","first-page":"1451","article-title":"Cationic immune complex arthritis in mice\u2014a new model. Synergistic effect of complement and interleukin-1","volume":"140","author":"van Lent","year":"1992","journal-title":"Am J Pathol"},{"key":"10.1006\/cyto.1999.0503_RF8","first-page":"1226","article-title":"In vivo role of phagocytic synovial lining cells in onset of experimental arthritis","volume":"143","author":"van Lent","year":"1993","journal-title":"Am J Pathol"},{"key":"10.1006\/cyto.1999.0503_RF9","first-page":"321","article-title":"Early cartilage degradation in cationic immune complex arthritis in mice: relative role of interleukin 1, the polymorphonuclear cell (PMN) and PMN elastase","volume":"21","author":"van Lent","year":"1994","journal-title":"J Rheumatol"},{"key":"10.1006\/cyto.1999.0503_RF10","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1016\/0952-7915(94)90006-X","article-title":"Chemokines, leucocyte trafficking, and inflammation","volume":"6","author":"Schall","year":"1994","journal-title":"Curr Opin Immunol"},{"key":"10.1006\/cyto.1999.0503_RF11","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.4049\/jimmunol.157.4.1736","article-title":"Identification of mouse granulocyte chemotactic protein-2 from fibroblasts and epithelial cells. Functional comparison with natural KC and macrophage inflammatory protein-2","volume":"157","author":"Wuyts","year":"1996","journal-title":"J Immunol"},{"key":"10.1006\/cyto.1999.0503_RF12","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/1043-4666(94)90009-4","article-title":"Differential expression of the small inducible cytokines GRO \u03b1 and GRO \u03b2 by synovial fibroblasts in chronic arthritis: possible role in growth regulation","volume":"6","author":"Hogan","year":"1994","journal-title":"Cytokine"},{"key":"10.1006\/cyto.1999.0503_RF13","doi-asserted-by":"crossref","first-page":"3439","DOI":"10.4049\/jimmunol.158.7.3439","article-title":"Requirement for C-X-C chemokines (macrophage inflammatory protein-2 and cytokine-induced neutrophil chemoattractant) in IgG immune complex-induced lung injury","volume":"158","author":"Sanley","year":"1997","journal-title":"J Immunol"},{"key":"10.1006\/cyto.1999.0503_RF14","doi-asserted-by":"crossref","first-page":"1545","DOI":"10.1002\/art.1780390915","article-title":"Phagocytic lining cells determine local expression of inflammation in type II collagen-induced arthritis","volume":"39","author":"van Lent","year":"1996","journal-title":"Arthritis Rheum"},{"key":"10.1006\/cyto.1999.0503_RF15","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1002\/art.1780400209","article-title":"Role of interleukin-4 and interleukin-10 in murine collagen-induced arthritis: protective effect of interleukin-4 and interleukin-10 treatment on cartilage destruction","volume":"40","author":"Joosten","year":"1997","journal-title":"Arthritis Rheum"},{"key":"10.1006\/cyto.1999.0503_RF16","doi-asserted-by":"crossref","first-page":"3815","DOI":"10.4049\/jimmunol.147.11.3815","article-title":"IL-10 inhibits the cytokine production by activated macrophages","volume":"147","author":"Fiorentino","year":"1997","journal-title":"J Immunol"},{"key":"10.1006\/cyto.1999.0503_RF17","first-page":"47","article-title":"The effects of IL-10 on interleukin-1 receptor antagonist and interleukin-1b production in human monocytes and neutrophils","volume":"13","author":"Jenkins","year":"1994","journal-title":"Lymphokine Cytokine Res"},{"key":"10.1006\/cyto.1999.0503_RF18","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/S0140-6736(89)90430-3","article-title":"Inhibitory effect of TNF\u03b1 antibodies on synovial cell interleukin-1 production in rheumatoid arthritis","volume":"2","author":"Brennan","year":"1989","journal-title":"Lancet"},{"key":"10.1006\/cyto.1999.0503_RF19","doi-asserted-by":"crossref","first-page":"690","DOI":"10.1006\/cyto.1998.0372","article-title":"Different roles of tumor necrosis factor-\u03b1 and interleukin-1 in murine streptococcal cell wall arthritis","volume":"10","author":"Kuiper","year":"1998","journal-title":"Cytokine"},{"key":"10.1006\/cyto.1999.0503_RF20","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1084\/jem.146.3.857","article-title":"Autoimmunity to type II collagen: an experimental model of arthritis","volume":"146","author":"Trentham","year":"1977","journal-title":"J Exp Med"},{"key":"10.1006\/cyto.1999.0503_RF21","doi-asserted-by":"crossref","first-page":"4615","DOI":"10.4049\/jimmunol.160.9.4615","article-title":"Transient gene transfer of IL-12 regulates chemokine expression and disease severity in experimental arthritis","volume":"160","author":"Parks","year":"1998","journal-title":"J Immunol"},{"key":"10.1006\/cyto.1999.0503_RF22","doi-asserted-by":"crossref","first-page":"4094","DOI":"10.4049\/jimmunol.159.8.4094","article-title":"Dual role of IL-12 in early stages of murine collagen type II arthritis","volume":"159","author":"Joosten","year":"1997","journal-title":"J Immunol"},{"key":"10.1006\/cyto.1999.0503_RF23","doi-asserted-by":"crossref","first-page":"2994","DOI":"10.1002\/eji.1830271136","article-title":"Immune complexes are potent inhibitors of interleukin-12 secretion by human monocytes","volume":"27","author":"Berger","year":"1997","journal-title":"Eur J Immunol"},{"key":"10.1006\/cyto.1999.0503_RF24","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/0022-5320(72)90087-1","article-title":"Use of cationized ferritin as a label of negative charges on cell surfaces","volume":"38","author":"Danon","year":"1972","journal-title":"J Ultrastruct Res"},{"key":"10.1006\/cyto.1999.0503_RF25","first-page":"139","article-title":"Streptococcal cell wall-induced arthritis and flare-up reaction in mice induced by homologous or heterologous cell walls","volume":"133","author":"van den Broek","year":"1988","journal-title":"Am J Pathol"},{"key":"10.1006\/cyto.1999.0503_RF26","doi-asserted-by":"crossref","first-page":"1585","DOI":"10.1084\/jem.146.6.1585","article-title":"Arthritis in rats after systemic injection of streptococcal cells or cell walls","volume":"146","author":"Cromartie","year":"1977","journal-title":"J Exp Med"},{"key":"10.1006\/cyto.1999.0503_RF27","first-page":"680","article-title":"Preparations of 131I-labeled growth hormone of high specific activity","volume":"227","author":"Hunter","year":"1962","journal-title":"Nature"},{"key":"10.1006\/cyto.1999.0503_RF28","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1002\/jlb.53.6.636","article-title":"Perspective role of polymorphonuclear leucocytes and their integrins (CD-11\/18) in the local or systemic toxicity of lipopolysaccharide","volume":"53","author":"Chang","year":"1993","journal-title":"J Leuc Biol"},{"key":"10.1006\/cyto.1999.0503_RF29","doi-asserted-by":"crossref","first-page":"59","DOI":"10.3109\/03009748309102006","article-title":"99mTc-pertechnetate uptake measurements in the rabbit knee joint","volume":"12","author":"van Beusekom","year":"1983","journal-title":"Scand J Rheumatol"},{"key":"10.1006\/cyto.1999.0503_RF30","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1007\/BF01978915","article-title":"Quantification of arthritis by99mTc uptake measurements in the mouse knee joint: correlation with histological joint inflammation scores","volume":"14","author":"Lens","year":"1984","journal-title":"Agents Actions"},{"key":"10.1006\/cyto.1999.0503_RF31","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1002\/jlb.46.5.461","article-title":"Functions of purified mouse neutrophils isolated from gelatin sponges","volume":"46","author":"Middleton","year":"1989","journal-title":"J Leukoc Biol"},{"key":"10.1006\/cyto.1999.0503_RF32","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1002\/art.1780380204","article-title":"Role of interleukin-1, tumor necrosis factor \u03b1, and interleukin-6 in cartilage proteoglycan metabolism and destruction; Effect of in situ blocking in murine antigen- and zymosan induced arthritis","volume":"38","author":"van de Loo","year":"1995","journal-title":"Arthritis Rheum"},{"key":"10.1006\/cyto.1999.0503_RF33","first-page":"239","article-title":"Role of interleukin-1 in antigen-induced exacerbations of murine arthritis","volume":"146","author":"van de Loo","year":"1995","journal-title":"Am J Pathol"},{"key":"10.1006\/cyto.1999.0503_RF34","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1152\/jappl.1995.79.5.1497","article-title":"Endurance run increases circulating IL-6 and IL-1ra but downregulates ex vivo TNF\u03b1 and IL-1\u03b2 production","volume":"79","author":"Drenth","year":"1995","journal-title":"J Appl Physiol"},{"key":"10.1006\/cyto.1999.0503_RF35","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/0022-1759(87)90025-1","article-title":"A simple sensitive assay for interleukin-1 which is unresponsive to 103U\/ml of interleukin-2","volume":"99","author":"Gearing","year":"1987","journal-title":"J Immunol Methods"},{"key":"10.1006\/cyto.1999.0503_RF36","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/0022-1759(88)90422-X","article-title":"An improved sensitive and simple microassay of mouse complement","volume":"108","author":"de Waal","year":"1988","journal-title":"J Immunol Methods"}],"container-title":["Cytokine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043466699905033?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043466699905033?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,4,4]],"date-time":"2023-04-04T16:12:05Z","timestamp":1680624725000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1043466699905033"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,12]]},"references-count":36,"journal-issue":{"issue":"12","published-print":{"date-parts":[[1999,12]]}},"alternative-id":["S1043466699905033"],"URL":"https:\/\/doi.org\/10.1006\/cyto.1999.0503","relation":{},"ISSN":["1043-4666"],"issn-type":[{"value":"1043-4666","type":"print"}],"subject":[],"published":{"date-parts":[[1999,12]]}}}