{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T16:08:39Z","timestamp":1784909319726,"version":"3.55.0"},"reference-count":41,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2002,5,1]],"date-time":"2002-05-01T00:00:00Z","timestamp":1020211200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Environmental Research"],"published-print":{"date-parts":[[2002,5]]},"DOI":"10.1006\/enrs.2002.4357","type":"journal-article","created":{"date-parts":[[2002,9,16]],"date-time":"2002-09-16T15:46:35Z","timestamp":1032191195000},"page":"29-37","source":"Crossref","is-referenced-by-count":57,"title":["Short-Term Effects of Low-Level Air Pollution on Respiratory Health of Adults Suffering from Moderate to Severe Asthma"],"prefix":"10.1006","volume":"89","author":[{"given":"H\u00e9l\u00e8ne","family":"Desqueyroux","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Claude","family":"Pujet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Prosper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabien","family":"Squinazi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabelle","family":"Momas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1006\/enrs.2002.4357_RF1","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1002\/(SICI)1099-1263(1998090)18:5<307::AID-JAT508>3.0.CO;2-K","article-title":"Cytotoxicity, pro-oxidant effects and antioxidant depletion in rat lung alveolar macrophages exposed to ultrafine titanium dioxide","volume":"18","author":"Afaq","year":"1998","journal-title":"J. Appl. Toxicol."},{"key":"10.1006\/enrs.2002.4357_RF2","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1183\/09031936.97.10051064","article-title":"Air pollution and daily admissions for chronic obstructive pulmonary disease in 6 European cities: Results from the APHEA project","volume":"10","author":"Anderson","year":"1997","journal-title":"Eur. Respir. J."},{"key":"10.1006\/enrs.2002.4357_RF3","unstructured":"Conseil D\u00e9partemental d'Hygi\u00e8ne de Paris, 1997, La Qualit\u00e9 de l'air \u00e0 Paris en 1996, Rapport \u00c9labor\u00e9 \u00e0 Partir des Donn\u00e9es de: AIRPARIF, Laboratoire Central de la Pr\u00e9fecture de Police, Laboratoire d'Hygi\u00e8ne de la Ville de Paris, Paris."},{"key":"10.1006\/enrs.2002.4357_RF4","doi-asserted-by":"crossref","first-page":"S42","DOI":"10.1136\/jech.50.Suppl_1.s42","article-title":"Short term respiratory health effects of ambient air pollution: Results of the APHEA project in Paris","volume":"50","author":"Dab","year":"1996","journal-title":"J. Epidemiol. Commun. Health"},{"key":"10.1006\/enrs.2002.4357_RF5","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1289\/ehp.97105622","article-title":"The effect of outdoor spore concentration on daily asthma severity","volume":"105","author":"Delfino","year":"1997","journal-title":"Environ. Health Perspect."},{"key":"10.1006\/enrs.2002.4357_RF6","first-page":"361","article-title":"Air pollution and health: A synthesis of longitudinal panel studies published from 1987 to 1998","volume":"47","author":"Desqueyroux","year":"1999","journal-title":"Rev. Epidemiol. Sante Publ."},{"key":"10.1006\/enrs.2002.4357_RF7","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1172\/JCI117478","article-title":"Diesel exhaust particles induce local IgE production in vivo and alter the pattern of IgE messenger RNA isoforms","volume":"94","author":"Diaz-Sanchez","year":"1994","journal-title":"J. Clin. Invest."},{"key":"10.1006\/enrs.2002.4357_RF8","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1080\/009841097160492","article-title":"Soluble transition metals mediate residual oil fly ash induced acute lung injury","volume":"50","author":"Dreher","year":"1997","journal-title":"J. Toxicol. Environ. Health"},{"key":"10.1006\/enrs.2002.4357_RF9","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1165\/ajrcmb.19.3.3143","article-title":"Combined nasal challenge with diesel exhaust particles and allergen induces in vivo IgE isotype switching","volume":"19","author":"Fujieda","year":"1998","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1006\/enrs.2002.4357_RF10","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1006\/enrs.1997.3732","article-title":"Metal and sulfate composition of residual oil fly ash determines airway hyperreactivity and lung injury in rats","volume":"72","author":"Gavett","year":"1997","journal-title":"Environ. Res."},{"key":"10.1006\/enrs.2002.4357_RF11","doi-asserted-by":"crossref","first-page":"2105","DOI":"10.1164\/ajrccm.155.6.9196122","article-title":"Acute effects of summer air pollution on respiratory health of asthmatic children","volume":"157","author":"Gielen","year":"1997","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1006\/enrs.2002.4357_RF12","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1136\/thx.50.2.149","article-title":"Effects of air pollution on symptoms and peak expiratory flow measurements in subjects with obstructive airways disease","volume":"50","author":"Higgins","year":"1995","journal-title":"Thorax"},{"key":"10.1006\/enrs.2002.4357_RF13","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1183\/09031936.98.11030686","article-title":"Asthma severity and susceptibility to air pollution","volume":"11","author":"Hiltermann","year":"1998","journal-title":"Eur. Respir. J."},{"key":"10.1006\/enrs.2002.4357_RF14","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/S0300-483X(97)03664-0","article-title":"Airborne particulate matter modulates the production of reactive oxygen species in human polymorphonuclear granulocytes","volume":"120","author":"Hitzfeld","year":"1997","journal-title":"Toxicology"},{"key":"10.1006\/enrs.2002.4357_RF15","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/S0300-483X(97)00096-6","article-title":"Murine strain differences in allergic airway inflammation and immunoglobulin production by a combination of antigen and diesel exhaust particles","volume":"122","author":"Ichinose","year":"1997","journal-title":"Toxicology"},{"key":"10.1006\/enrs.2002.4357_RF16","first-page":"204","article-title":"Pulmonary responses to oil fly ash particles in the rat differ by virtue of their specific soluble metals","volume":"43","author":"Kodavanti","year":"1998","journal-title":"Toxicol. Sci."},{"key":"10.1006\/enrs.2002.4357_RF17","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1289\/ehp.971051078","article-title":"The semi-individual study in air pollution epidemiology: A valid design as compared to ecologic studies","volume":"105","author":"K\u00fcnzli","year":"1997","journal-title":"Environ. Health Perspect."},{"key":"10.1006\/enrs.2002.4357_RF18","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/S0013-9351(87)80033-6","article-title":"Times series analyses of respiratory responses to indoor and outdoor environmental phenomena","volume":"43","author":"Lebowitz","year":"1987","journal-title":"Environ. Res."},{"key":"10.1006\/enrs.2002.4357_RF19","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1093\/biomet\/73.1.13","article-title":"Longitudinal data analysis using generalized linear models","volume":"73","author":"Liang","year":"1986","journal-title":"Biometrika"},{"key":"10.1006\/enrs.2002.4357_RF20","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0300-483X(97)00075-9","article-title":"Diesel exhaust particles and carbon black have adjuvant activity on the local lymph node response and systematic IgE production to ovalbumin","volume":"121","author":"Lovik","year":"1997","journal-title":"Toxicology"},{"key":"10.1006\/enrs.2002.4357_RF21","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0140-6736(91)90346-Q","article-title":"Effect of low concentrations of ozone on inhaled allergen responses in asthmatic subjects","volume":"338","author":"Molfino","year":"1991","journal-title":"Lancet"},{"key":"10.1006\/enrs.2002.4357_RF22","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1111\/j.1398-9995.1993.tb02402.x","article-title":"Pulmonary function changes in asthmatics associated with low-level SO2 and NO2 air pollution, weather, and medicine intake","volume":"48","author":"Moseholm","year":"1993","journal-title":"Allergy"},{"key":"10.1006\/enrs.2002.4357_RF23","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1080\/00039899809605716","article-title":"Short-term effects of low-level winter pollution on respiratory health of asthmatic adults","volume":"53","author":"Neukirch","year":"1998","journal-title":"Arch. Environ. Health"},{"key":"10.1006\/enrs.2002.4357_RF24","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S0300-483X(97)00150-9","article-title":"The adjuvant activity of diesel exhaust particles and carbon black on systemic IgE production to ovalbumin in mice after intranasal instillation","volume":"124","author":"Nilsen","year":"1997","journal-title":"Toxicology"},{"key":"10.1006\/enrs.2002.4357_RF25","doi-asserted-by":"crossref","first-page":"694","DOI":"10.2105\/AJPH.81.6.694","article-title":"Asthmatic responses to airborne acid aerosols","volume":"81","author":"Ostro","year":"1991","journal-title":"Am. J. Public Health"},{"key":"10.1006\/enrs.2002.4357_RF26","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1136\/thx.54.3.268","article-title":"How much asthma is really attributable to atopy","volume":"54","author":"Pearce","year":"1999","journal-title":"Thorax"},{"key":"10.1006\/enrs.2002.4357_RF27","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1006\/enrs.1997.3750","article-title":"Effects of ultrafine and fine particles in urban air on peak expiratory flow among children with asthmatic symptoms","volume":"74","author":"Pekkanen","year":"1997","journal-title":"Environ. Res."},{"key":"10.1006\/enrs.2002.4357_RF28","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1093\/oxfordjournals.aje.a008967","article-title":"Acute health effects of exposure to high levels of air pollution in Eastern Europe","volume":"144","author":"Peters","year":"1996","journal-title":"Am. J. Epidemiol."},{"key":"10.1006\/enrs.2002.4357_RF29","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.1164\/ajrccm.155.4.9105082","article-title":"Respiratory effects are associated with the number of ultrafine particles","volume":"155","author":"Peters","year":"1997","journal-title":"Am. J. Respir. Crit. Care Med."},{"key":"10.1006\/enrs.2002.4357_RF30","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1136\/jech.50.Suppl_1.s63","article-title":"Effects of air pollution on daily hospital admissions for respiratory disease in London between 1987\u201388 and 1991\u201392","volume":"50","author":"Ponce de Leon","year":"1996","journal-title":"J. Epidemiol. Commun. Health"},{"key":"10.1006\/enrs.2002.4357_RF31","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1164\/ajrccm\/144.3_Pt_1.668","article-title":"Respiratory health and PM10 pollution","volume":"144","author":"Pope","year":"1991","journal-title":"Am. Ref. Respir. Dis."},{"key":"10.1006\/enrs.2002.4357_RF32","unstructured":"Pujet, J. C, Racineux, J. L, Dubosq-Mathieu, B, and, Michel, F. B. 1994, Large survey on the quality of life of 18500 French asthmatics. First international conference on asthma education and management."},{"key":"10.1006\/enrs.2002.4357_RF33","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1006\/bbrc.1997.7373","article-title":"Evidence that exposure of particular air pollutants to human and rat alveolar macrophages leads to differential oxidative response","volume":"240","author":"Rahman","year":"1997","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1006\/enrs.2002.4357_RF34","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1183\/09031936.98.11030677","article-title":"Short-term effect of winter air pollution on respiratory health of asthmatic children in Paris","volume":"11","author":"S\u00e9gala","year":"1998","journal-title":"Eur. Respir. J."},{"key":"10.1006\/enrs.2002.4357_RF35","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1136\/jech.50.Suppl_1.s22","article-title":"Short term effects of air pollution on emergency hospital admissions for respiratory disease: Results of the APHEA project in two major cities in The Netherlands, 1977\u201389","volume":"50","author":"Shouten","year":"1996","journal-title":"J. Epidemiol. Commun. Health"},{"key":"10.1006\/enrs.2002.4357_RF36","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1080\/00039899809605689","article-title":"Short-term effects of air pollution on hospital admissions of respiratory diseases in Europe: A quantitative summary of APHEA study results","volume":"53","author":"Spix","year":"1998","journal-title":"Arch. Environ. Health"},{"key":"10.1006\/enrs.2002.4357_RF37","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S0300-483X(98)00075-4","article-title":"Human IgE production in hu-PBL-SCID mice injected with birch pollen and diesel exhaust particles","volume":"128","author":"Steinsvik","year":"1998","journal-title":"Toxicology"},{"key":"10.1006\/enrs.2002.4357_RF38","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1159\/000023953","article-title":"Thunderstorm asthma due to grass pollen","volume":"116","author":"Suphioglu","year":"1998","journal-title":"Int. Arch. Allergy Immunol."},{"key":"10.1006\/enrs.2002.4357_RF39","doi-asserted-by":"crossref","first-page":"1146","DOI":"10.1183\/09031936.96.09061146","article-title":"Asthmatic bronchial hyperresponsiveness varies with ambient levels of summertime air pollution","volume":"9","author":"Taggart","year":"1996","journal-title":"Eur. Respir. J."},{"key":"10.1006\/enrs.2002.4357_RF40","doi-asserted-by":"crossref","first-page":"S71","DOI":"10.1136\/jech.50.Suppl_1.s71","article-title":"Short term effects of urban air pollution on respiratory health in Milan, Italy, 1980\u20131989","volume":"50","author":"Vigotti","year":"1996","journal-title":"J. Epidemiol. Commun. Health"},{"key":"10.1006\/enrs.2002.4357_RF41","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1006\/taap.1997.8102","article-title":"Inhalation of high concentrations of low toxicity dusts in rats results in impaired pulmonary clearance mechanisms and persistent inflammation","volume":"145","author":"Warheit","year":"1997","journal-title":"Toxicol. Appl. Pharmacol."}],"container-title":["Environmental Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013935102943574?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0013935102943574?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,4,4]],"date-time":"2023-04-04T05:54:08Z","timestamp":1680587648000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0013935102943574"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,5]]},"references-count":41,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2002,5]]}},"alternative-id":["S0013935102943574"],"URL":"https:\/\/doi.org\/10.1006\/enrs.2002.4357","relation":{},"ISSN":["0013-9351"],"issn-type":[{"value":"0013-9351","type":"print"}],"subject":[],"published":{"date-parts":[[2002,5]]}}}