{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T05:04:43Z","timestamp":1762146283444,"version":"build-2065373602"},"reference-count":35,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2001,7,1]],"date-time":"2001-07-01T00:00:00Z","timestamp":993945600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2001,7,1]],"date-time":"2001-07-01T00:00:00Z","timestamp":993945600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Experimental Cell Research"],"published-print":{"date-parts":[[2001,7]]},"DOI":"10.1006\/excr.2001.5250","type":"journal-article","created":{"date-parts":[[2002,9,16]],"date-time":"2002-09-16T11:46:35Z","timestamp":1032176795000},"page":"233-242","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Molecular and Functional Characterization of the Four-Transmembrane Molecule L6 in Epidermal Keratinocytes"],"prefix":"10.1006","volume":"267","author":[{"given":"Julian","family":"Storim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Friedl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Birgit M.","family":"Schaefer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Bechtel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reiner","family":"Wallich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael D.","family":"Kramer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeannette","family":"Reinartz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1006\/excr.2001.5250_RF1","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1111\/1523-1747.ep12613668","article-title":"Adhesion molecules. I. Keratinocyte\u2013keratinocyte interactions: Cadherins and pemphigus","volume":"104","author":"Amagai","year":"1995","journal-title":"J. Invest. Dermatol."},{"key":"10.1006\/excr.2001.5250_RF2","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/S0065-2776(08)60503-9","article-title":"Cell adhesion molecules as targets of autoantibodies in pemphigus and pemphigoid, bullous diseases due to defective epidermal cell adhesion","volume":"53","author":"Stanley","year":"1993","journal-title":"Adv. Immunol."},{"key":"10.1006\/excr.2001.5250_RF3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1242\/jcs.101.1.1","article-title":"Wound repair, keratinocyte activation and integrin modulation","volume":"101","author":"Grinnell","year":"1992","journal-title":"J. Cell Sci."},{"key":"10.1006\/excr.2001.5250_RF4","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1006\/bbrc.1997.6945","article-title":"Towards a molecular definition of keratinocyte activation after acute injury to stratified epithelia","volume":"236","author":"Coulombe","year":"1997","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1006\/excr.2001.5250_RF5","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1006\/excr.1996.0323","article-title":"Dispase-mediated basal detachment of cultured keratinocytes induces urokinase-type plasminogen activator (uPA) and its receptor (uPA-R, CD87)","volume":"228","author":"Schaefer","year":"1996","journal-title":"Exp. Cell Res."},{"key":"10.1006\/excr.2001.5250_RF6","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1034\/j.1600-0625.2000.009001058.x","article-title":"Immunohistochemical and molecular characterization of cultured keratinocytes after dispase-mediated detachment from the growth substratum","volume":"9","author":"Schaefer","year":"2000","journal-title":"Exp. Dermatol."},{"key":"10.1006\/excr.2001.5250_RF7","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1111\/1523-1747.ep12460937","article-title":"Involvement of urokinase-type plasminogen activator in acantholysis induced by pemphigus IgG","volume":"89","author":"Morioka","year":"1987","journal-title":"J. Invest. Dermatol."},{"key":"10.1006\/excr.2001.5250_RF8","doi-asserted-by":"crossref","first-page":"155","DOI":"10.3109\/08916939608995339","article-title":"Plasminogen activation in bullous pemphigoid immunohistology reveals urokinase type plasminogen activator, its receptor and plasminogen activator inhibitor type-2 in lesional epidermis","volume":"23","author":"Schaefer","year":"1996","journal-title":"Autoimmunity"},{"key":"10.1006\/excr.2001.5250_RF9","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1111\/j.1365-2133.1996.tb03881.x","article-title":"Plasminogen activator system in pemphigus vulgaris","volume":"135","author":"Schaefer","year":"1996","journal-title":"Br. J. Dermatol."},{"key":"10.1006\/excr.2001.5250_RF10","doi-asserted-by":"crossref","first-page":"3503","DOI":"10.1073\/pnas.89.8.3503","article-title":"Cloning and expression of the tumor-associated antigen L6","volume":"89","author":"Marken","year":"1992","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1006\/excr.2001.5250_RF11","first-page":"3917","article-title":"Monoclonal mouse antibodies raised against human lung carcinoma","volume":"46","author":"Hellstr\u00f6m","year":"1986","journal-title":"Cancer Res."},{"key":"10.1006\/excr.2001.5250_RF12","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/0167-5699(94)90222-4","article-title":"The ins and outs of the transmembrane 4 superfamily","volume":"15","author":"Wright","year":"1994","journal-title":"Immunol. Today"},{"key":"10.1006\/excr.2001.5250_RF13","first-page":"67","article-title":"Association of TM4SF proteins with integrins: Relevance to cancer","volume":"1287","author":"Hemler","year":"1996","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1006\/excr.2001.5250_RF14","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1096\/fasebj.11.6.9194523","article-title":"The tetraspanin superfamily: Molecular facilitators","volume":"11","author":"Maecker","year":"1997","journal-title":"FASEB J."},{"key":"10.1006\/excr.2001.5250_RF15","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/S0955-0674(98)80032-X","article-title":"Integrin associated proteins","volume":"10","author":"Hemler","year":"1998","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1006\/excr.2001.5250_RF16","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1111\/j.1365-2133.1997.tb01544.x","article-title":"Expression of tetra-spans transmembrane family (CD9, CD37, CD53, CD63, CD81 and CD82) in normal and neoplastic human keratinocytes: An association of CD9 with alpha 3 beta 1 integrin","volume":"137","author":"Okochi","year":"1997","journal-title":"Br. J. Dermatol."},{"key":"10.1006\/excr.2001.5250_RF17","doi-asserted-by":"crossref","first-page":"1126","DOI":"10.1046\/j.1523-1747.2000.00998.x","article-title":"Tetraspanins are localized at motility-related structures and involved in normal human keratinocyte wound healing migration","volume":"114","author":"Penas","year":"2000","journal-title":"J. Invest. Dermatol."},{"key":"10.1006\/excr.2001.5250_RF18","doi-asserted-by":"crossref","first-page":"1594","DOI":"10.1110\/ps.9.8.1594","article-title":"The L6 membrane proteins\u2014A new four-transmembrane superfamily","volume":"9","author":"Wright","year":"2000","journal-title":"Prot. Sci."},{"key":"10.1006\/excr.2001.5250_RF19","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1007\/BF02615077","article-title":"The establishment of two cell lines from the insect Spodoptera frugiperda (Lepidoptera; Noctuidae)","volume":"13","author":"Vaughn","year":"1977","journal-title":"In Vitro"},{"key":"10.1006\/excr.2001.5250_RF20","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/0092-8674(81)90282-8","article-title":"SV40-transformed simian cells support the replication of early SV40 mutants","volume":"23","author":"Gluzman","year":"1981","journal-title":"Cell"},{"key":"10.1006\/excr.2001.5250_RF21","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0022-1759(93)90384-J","article-title":"Enzyme-linked immunosorbent assays for plasminogen activators","volume":"162","author":"Buessecker","year":"1993","journal-title":"J. Immunol. Methods"},{"key":"10.1006\/excr.2001.5250_RF22","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/S0092-8674(75)80001-8","article-title":"Serial cultivation of strains of human epidermal keratinocytes: The formation of keratinizing colonies from single cells","volume":"6","author":"Rheinwald","year":"1975","journal-title":"Cell"},{"key":"10.1006\/excr.2001.5250_RF23","first-page":"101","article-title":"The keratinocyte as differentiated cell type","volume":"74","author":"Green","year":"1980","journal-title":"Harvey Lect."},{"key":"10.1006\/excr.2001.5250_RF24","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1083\/jcb.106.3.761","article-title":"Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line","volume":"106","author":"Boukamp","year":"1988","journal-title":"J. Cell Biol."},{"key":"10.1006\/excr.2001.5250_RF25","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1006\/abio.1993.1060","article-title":"Maximal expression of recombinant cDNAs in COS cells for use in expression cloning","volume":"208","author":"Kluxen","year":"1993","journal-title":"Anal. Biochem."},{"key":"10.1006\/excr.2001.5250_RF26","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/S0171-2985(11)80504-8","article-title":"Characterization of Borrelia burgdorferi associated antigens by monoclonal antibodies","volume":"181","author":"Kramer","year":"1990","journal-title":"Immunobiology"},{"key":"10.1006\/excr.2001.5250_RF27","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/0022-1759(93)90341-4","article-title":"Lymphocyte locomotion in three-dimensional collagen gels. Comparison of three quantitative methods for analysing cell trajectories","volume":"165","author":"Friedl","year":"1993","journal-title":"J. Immunol. Methods"},{"key":"10.1006\/excr.2001.5250_RF28","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/0003-2697(87)90021-2","article-title":"Single-step method of RNA isolation by acid guanidinium thiocyanate\u2013phenol\u2013chloroform extraction","volume":"162","author":"Chomczynski","year":"1987","journal-title":"Anal. Biochem."},{"key":"10.1006\/excr.2001.5250_RF29","doi-asserted-by":"crossref","first-page":"15,552","DOI":"10.1016\/S0021-9258(19)49571-9","article-title":"Chimeric L6 anti-tumor antibody. Genomic construction, expression, and characterization of the antigen binding site","volume":"267","author":"Fell","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1006\/excr.2001.5250_RF30","doi-asserted-by":"crossref","first-page":"7397","DOI":"10.1016\/S0021-9258(17)37298-8","article-title":"Membrane topology of the L6 antigen and identification of the protein epitope recognized by the L6 monoclonal antibody","volume":"269","author":"Marken","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1006\/excr.2001.5250_RF31","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1083\/jcb.141.3.791","article-title":"Regulation of endothelial cell motility by complexes of tetraspan molecules CD81\/TAPA-1 and CD151\/PETA-3 with alpha3 beta1 integrin localized at endothelial lateral junctions","volume":"141","author":"Yanez-Mo","year":"1998","journal-title":"J. Cell Biol."},{"key":"10.1006\/excr.2001.5250_RF32","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1083\/jcb.146.6.1375","article-title":"Function of alpha3beta1-tetraspanin protein complexes in tumor cell invasion. Evidence for the role of the complexes in production of matrix metalloproteinase 2 (MMP-2)","volume":"146","author":"Sugiura","year":"1999","journal-title":"J. Cell Biol."},{"key":"10.1006\/excr.2001.5250_RF33","doi-asserted-by":"crossref","first-page":"297","DOI":"10.3109\/15419069609010773","article-title":"Functional significance of CD9 association with beta 1 integrins in human epidermal keratinocytes","volume":"4","author":"Jones","year":"1996","journal-title":"Cell Adhes. Commun."},{"key":"10.1006\/excr.2001.5250_RF34","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1042\/bj3400103","article-title":"Selective tetraspan-integrin complexes (CD81\/alpha4beta1, CD151\/alpha3beta1, CD151\/alpha6beta1) under conditions disrupting tetraspan interactions","volume":"340","author":"Serru","year":"1999","journal-title":"Biochem. J."},{"key":"10.1006\/excr.2001.5250_RF35","doi-asserted-by":"crossref","first-page":"2657","DOI":"10.1002\/eji.1830261117","article-title":"CD9, CD63, CD81, and CD82 are components of a surface tetraspan network connected to HLA-DR and VLA integrins","volume":"26","author":"Rubinstein","year":"1996","journal-title":"Eur. J. Immunol."}],"container-title":["Experimental Cell Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014482701952504?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014482701952504?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T05:01:42Z","timestamp":1762146102000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014482701952504"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,7]]},"references-count":35,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2001,7]]}},"alternative-id":["S0014482701952504"],"URL":"https:\/\/doi.org\/10.1006\/excr.2001.5250","relation":{},"ISSN":["0014-4827"],"issn-type":[{"type":"print","value":"0014-4827"}],"subject":[],"published":{"date-parts":[[2001,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Molecular and Functional Characterization of the Four-Transmembrane Molecule L6 in Epidermal Keratinocytes","name":"articletitle","label":"Article Title"},{"value":"Experimental Cell Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1006\/excr.2001.5250","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2001 Academic Press. All rights reserved.","name":"copyright","label":"Copyright"}]}}