{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,22]],"date-time":"2026-01-22T17:22:45Z","timestamp":1769102565558,"version":"3.49.0"},"reference-count":41,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2001,8,1]],"date-time":"2001-08-01T00:00:00Z","timestamp":996624000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental Eye Research"],"published-print":{"date-parts":[[2001,8]]},"DOI":"10.1006\/exer.2001.1022","type":"journal-article","created":{"date-parts":[[2002,9,16]],"date-time":"2002-09-16T15:46:56Z","timestamp":1032191216000},"page":"167-178","source":"Crossref","is-referenced-by-count":11,"title":["Kappa Opioid Agonist-Induced Changes in IOP: Correlation with3H-NE Release and cAMP Accumulation"],"prefix":"10.1006","volume":"73","author":[{"given":"Tisha T","family":"Moore","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David E","family":"Potter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1006\/exer.2001.1022_RF1","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/0306-4522(93)90372-M","article-title":"Characterization of potassium currents in adult rat sensory neurons and modulation by opioids and cyclic AMP","volume":"56","author":"Akins","year":"1993","journal-title":"Neuroscience"},{"key":"10.1006\/exer.2001.1022_RF2","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/S0021-9258(17)31264-4","article-title":"Kappa opiate agonists inhibit calcium influx in rat spinal cord-dorsal root ganglion cocultures","volume":"264","author":"Attali","year":"1989","journal-title":"J. Biol. Chem."},{"key":"10.1006\/exer.2001.1022_RF3","doi-asserted-by":"crossref","first-page":"547","DOI":"10.3109\/02713688908995752","article-title":"Can UK-14 304-18 lower IOP in rabbits by a peripheral mechanism?","volume":"8","author":"Burke","year":"1989","journal-title":"Curr. Eye Res."},{"key":"10.1006\/exer.2001.1022_RF4","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/0024-3205(91)90154-4","article-title":"Opioid receptor-coupled second messenger systems","volume":"48","author":"Childers","year":"1991","journal-title":"Life Sci."},{"key":"10.1006\/exer.2001.1022_RF5","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1159\/000139438","article-title":"Oxymetazoline: potential mechanisms of inhibitory effects on aqueous humor dynamics","volume":"53","author":"Chu","year":"1996","journal-title":"Pharmacology"},{"key":"10.1006\/exer.2001.1022_RF6","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1007\/BF02002629","article-title":"Ocular instillation of naloxone increases intraocular pressure in morphine-addicted patients: a possible test for detecting the misuse of morphine","volume":"41","author":"Drago","year":"1985","journal-title":"Experientia"},{"key":"10.1006\/exer.2001.1022_RF7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF00504223","article-title":"Opiate receptors in the rabbit iris","volume":"315","author":"Drago","year":"1980","journal-title":"Naunyn-Schmiedeberg\u2019s Arch. Pharmacol."},{"key":"10.1006\/exer.2001.1022_RF8","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1111\/j.1440-1681.1985.tb02312.x","article-title":"Effects of opiates and opioids on intraocular pressure of rabbits and humans","volume":"12","author":"Drago","year":"1985","journal-title":"Clin. Exp. Pharmacol. Physiol."},{"key":"10.1006\/exer.2001.1022_RF9","first-page":"325","article-title":"Reports: ocular effects of diacetyl morphine and lysergic acid diethylamide in rabbit","volume":"14","author":"Green","year":"1975","journal-title":"Invest. Ophthalmol."},{"key":"10.1006\/exer.2001.1022_RF10","doi-asserted-by":"crossref","first-page":"5469","DOI":"10.1073\/pnas.84.15.5469","article-title":"Dynorphin A selectively reduces a large transient (N type) calcium current of mouse dorsal root ganglion neurons in cell culture","volume":"84","author":"Gross","year":"1987","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1006\/exer.2001.1022_RF11","doi-asserted-by":"crossref","first-page":"11429","DOI":"10.1073\/pnas.90.23.11429","article-title":"\u03ba-opioid receptors also increase potassium conductance","volume":"90","author":"Grudt","year":"1993","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1006\/exer.2001.1022_RF12","first-page":"19","article-title":"Inhibition of an N-like calcium channel by mu-opioid receptor activation in the human neuroblastoma cell line, SH-SY5Y","volume":"422","author":"Henderson","year":"1990","journal-title":"J. Physiol."},{"key":"10.1006\/exer.2001.1022_RF13","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1038\/325445a0","article-title":"The GTP-binding protein G0regulates neuronal calcium channels","volume":"325","author":"Hescheler","year":"1987","journal-title":"Nature (London)"},{"key":"10.1006\/exer.2001.1022_RF14","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1038\/269433a0","article-title":"Enkephalin effects on release of brain acetylcholine","volume":"269","author":"Jhamandas","year":"1977","journal-title":"Nature (London)"},{"key":"10.1006\/exer.2001.1022_RF15","first-page":"627","article-title":"Dynorphin-selective inhibition of adenylyl cyclase in guinea pig cerebellum membrane","volume":"36","author":"Konkoy","year":"1989","journal-title":"Mol. Pharmacol."},{"key":"10.1006\/exer.2001.1022_RF16","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1146\/annurev.pharmtox.40.1.389","article-title":"Molecular mechanisms and regulation of opioid receptor signaling","volume":"40","author":"Law","year":"2000","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"10.1006\/exer.2001.1022_RF17","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1001\/archopht.1948.00900030291006","article-title":"Effect of intramuscular administration of morphine, atropine, scopolamine, neostigmine on the human eye","volume":"40","author":"Leopold","year":"1948","journal-title":"Arch. Opthalmol."},{"key":"10.1006\/exer.2001.1022_RF18","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1007\/BF00505817","article-title":"Mutual interaction between presynaptic \u03b12-adrenoceptor and opioid \u03ba-receptors at the noradrenergic axon of rabbit cortex","volume":"334","author":"Limberger","year":"1986","journal-title":"Naunyn-Schmiedeberg\u2019s Arch. Pharmacol."},{"key":"10.1006\/exer.2001.1022_RF19","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1007\/BF00501109","article-title":"Influence of morphine and naloxone on the release of noradrenaline from rat brain cortex slices","volume":"283","author":"Montel","year":"1974","journal-title":"Naunyn-Schmiedeberg\u2019s Arch. Pharmacol."},{"key":"10.1006\/exer.2001.1022_RF20","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/0024-3205(83)90123-6","article-title":"The pupillary effects of opioids","volume":"33","author":"Murray","year":"1983","journal-title":"Life Sci."},{"key":"10.1006\/exer.2001.1022_RF21","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1016\/0014-4835(72)90009-7","article-title":"Cyclic-AMP in the aqueous humor: the effects of adrenergic agents","volume":"3","author":"Neufeld","year":"1972","journal-title":"Exp. Eye Res."},{"key":"10.1006\/exer.2001.1022_RF22","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1002\/cpt196893358","article-title":"The local effect of morphine, nalorphine, codeine on the diameter of the pupil of the eye","volume":"9","author":"Nomof","year":"1968","journal-title":"Clin. Pharm. Ther."},{"key":"10.1006\/exer.2001.1022_RF23","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/0166-2236(86)90038-X","article-title":"Opioid receptor types and membrane ion channels","volume":"9","author":"North","year":"1986","journal-title":"Trends Neurosci."},{"key":"10.1006\/exer.2001.1022_RF24","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1111\/j.1476-5381.1983.tb10023.x","article-title":"Opiate activation of potassium conductance inhibits calcium action potentials in rat locus coeruleus neurones","volume":"80","author":"North","year":"1983","journal-title":"Br. J. Pharmacol."},{"key":"10.1006\/exer.2001.1022_RF26","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1016\/0304-3940(91)90036-S","article-title":"Effect of opioid peptides on electrically evoked acetylcholine release from torpedo electromotor neurons","volume":"125","author":"Oron","year":"1991","journal-title":"Neurosci. Lett."},{"key":"10.1006\/exer.2001.1022_RF27","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1126\/science.179.4077.1011","article-title":"Opiate receptor: demonstration in nervous tissue","volume":"179","author":"Pert","year":"1973","journal-title":"Science"},{"key":"10.1006\/exer.2001.1022_RF28","doi-asserted-by":"crossref","first-page":"169","DOI":"10.3109\/02713688109001822","article-title":"Circadian rhythm in intraocular pressure: a rabbit model","volume":"1","author":"Rowland","year":"1981","journal-title":"Curr. Eye Res."},{"key":"10.1006\/exer.2001.1022_RF29","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1006\/exer.2000.0832","article-title":"Modulation of ocular hydrodynamics and iris function by bremazocine, a kappa opioid receptor agonist","volume":"70","author":"Russell","year":"2000","journal-title":"Exp. Eye Res."},{"key":"10.1006\/exer.2001.1022_RF30","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/0896-6273(91)90117-I","article-title":"Activation of mu opioid receptors inhibits transient high- and low-threshold Ca2+currents, but spares a sustained current","volume":"6","author":"Schroeder","year":"1991","journal-title":"Neuron"},{"key":"10.1006\/exer.2001.1022_RF31","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/0304-3940(90)90772-2","article-title":"Opiates inhibit pedunculopontine neurones in guinea pig brainstem slices","volume":"119","author":"Serafin","year":"1990","journal-title":"Neurosci. Lett."},{"key":"10.1006\/exer.2001.1022_RF32","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/0006-8993(89)90059-0","article-title":"Dual opioid modulation of the action potential duration of mouse dorsal root ganglion neurons in culture","volume":"491","author":"Shen","year":"1989","journal-title":"Brain Res."},{"key":"10.1006\/exer.2001.1022_RF33","doi-asserted-by":"crossref","first-page":"1947","DOI":"10.1073\/pnas.70.7.1947","article-title":"Stereospecific binding of the potent narcotic analgesic 3H-etorphine to rat brain homogenate","volume":"70","author":"Simon","year":"1973","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1006\/exer.2001.1022_RF34","first-page":"648","article-title":"Activation of kappa opioid receptors by U50488H and morphine enhances the release of substance P from rat trigeminal nucleus slices","volume":"264","author":"Suarez-Roca","year":"1993","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1006\/exer.2001.1022_RF35","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1111\/j.1600-0773.1973.tb01539.x","article-title":"Characteristics of the \u201creceptor\u201d for narcotic analgesics in synaptic plasma membrane fraction from rat brain","volume":"33","author":"Terenius","year":"1973","journal-title":"Acta Pharmacol. Toxicol."},{"key":"10.1006\/exer.2001.1022_RF36","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1111\/j.1748-1716.1972.tb05329.x","article-title":"The action of physostigmine, morphine, cyclopentalate and homatropine on the secretion and outflow of aqueous humor in the rabbit eye","volume":"86","author":"Uusitalo","year":"1972","journal-title":"Acta Physiol. Scand."},{"key":"10.1006\/exer.2001.1022_RF37","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1016\/0028-3908(87)90077-3","article-title":"Opioid receptor regulation of the release of NE in brain","volume":"26","author":"Werling","year":"1987","journal-title":"Neuropharmacology"},{"key":"10.1006\/exer.2001.1022_RF38","first-page":"1103","article-title":"Selective tolerance at mu and kappa opioid receptors modulating norepinephrine release in guinea pig cortex","volume":"247","author":"Werling","year":"1988","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1006\/exer.2001.1022_RF39","first-page":"49","article-title":"Dynorphin and neoendorphin peptides decrease dorsal root ganglion neuron calcium-dependent action potential duration","volume":"234","author":"Werz","year":"1985","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1006\/exer.2001.1022_RF40","first-page":"489","article-title":"Opiate-receptor interactions on single locus coeruleus neurons","volume":"26","author":"Williams","year":"1984","journal-title":"Mol. Pharmacol."},{"key":"10.1006\/exer.2001.1022_RF41","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/0006-8993(88)91191-2","article-title":"Effect of opioid peptides on the paraventricular nucleus of the guinea pig hypothalamus is mediated by \u03bc-type receptors","volume":"445","author":"Wuarin","year":"1988","journal-title":"Brain Res."},{"key":"10.1006\/exer.2001.1022_RF42","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1016\/S0021-9258(17)36053-2","article-title":"A human neuroblastoma cell line expresses mu and delta opioid receptor sites","volume":"261","author":"Yu","year":"1986","journal-title":"J. Biol. Chem."}],"container-title":["Experimental Eye Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001448350191022X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001448350191022X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,5,3]],"date-time":"2021-05-03T02:55:33Z","timestamp":1620010533000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S001448350191022X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,8]]},"references-count":41,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2001,8]]}},"alternative-id":["S001448350191022X"],"URL":"https:\/\/doi.org\/10.1006\/exer.2001.1022","relation":{},"ISSN":["0014-4835"],"issn-type":[{"value":"0014-4835","type":"print"}],"subject":[],"published":{"date-parts":[[2001,8]]}}}