{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T17:04:34Z","timestamp":1758906274946},"reference-count":45,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2001,10,1]],"date-time":"2001-10-01T00:00:00Z","timestamp":1001894400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental Eye Research"],"published-print":{"date-parts":[[2001,10]]},"DOI":"10.1006\/exer.2001.1057","type":"journal-article","created":{"date-parts":[[2002,9,16]],"date-time":"2002-09-16T15:46:56Z","timestamp":1032191216000},"page":"521-532","source":"Crossref","is-referenced-by-count":26,"title":["Anaylsis of Birefringence during Wound Healing and Remodeling following Alkali Burns in Rabbit Cornea"],"prefix":"10.1006","volume":"73","author":[{"given":"Yifei","family":"Huang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keith M","family":"Meek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mae-Wan","family":"Ho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher A","family":"Paterson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1006\/exer.2001.1057_RF1","first-page":"141","article-title":"Collagen organization in the interspinous ligament and its relationship to tissue function","volume":"155","author":"Aspden","year":"1987","journal-title":"J. Anat."},{"key":"10.1006\/exer.2001.1057_RF2","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1001\/archopht.1969.00990020097023","article-title":"Prevention of the ulcers of the alkali-burned cornea: preliminary studies with collagenase inhibitors","volume":"82","author":"Brown","year":"1969","journal-title":"Arch. Ophthalmol."},{"key":"10.1006\/exer.2001.1057_RF3","first-page":"107","article-title":"Inhibition of alkali induced corneal ulceration and perforation by a thio peptide","volume":"31","author":"Burns","year":"1990","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1006\/exer.2001.1057_RF4","doi-asserted-by":"crossref","first-page":"2065","DOI":"10.1128\/AAC.34.11.2065","article-title":"Inhibition of pseudomonas aeruginosa elastase and pseudomonas keratitis using a thio-based peptide","volume":"34","author":"Burns","year":"1990","journal-title":"Antimicrob. Agents Chemo."},{"key":"10.1006\/exer.2001.1057_RF5","first-page":"16","article-title":"Inhibition of purified collagenase from alkali-burned rabbit corneas","volume":"30","author":"Burns","year":"1989","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1006\/exer.2001.1057_RF6","first-page":"767","article-title":"Heterogeneity of collagen in rabbit cornea type III collagen","volume":"29","author":"Cintron","year":"1988","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1006\/exer.2001.1057_RF7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/02713688109019966","article-title":"Quantitative analysis of collagen from normal developing corneas and corneal scars","volume":"1","author":"Cintron","year":"1981","journal-title":"Curr. Eye Res."},{"key":"10.1006\/exer.2001.1057_RF8","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1007\/BF00737836","article-title":"Fibre-buckling in composite systems: a model for the ultrastructure of uncalcified collagen tissues","volume":"9","author":"Dale","year":"1974","journal-title":"J. Mater. Sci."},{"key":"10.1006\/exer.2001.1057_RF9","doi-asserted-by":"crossref","first-page":"5199","DOI":"10.1016\/S0021-9258(19)34106-7","article-title":"Thiol-based inhibitors of mammalian collagenase","volume":"265","author":"Darlak","year":"1990","journal-title":"J. Biol. Chem."},{"key":"10.1006\/exer.2001.1057_RF10","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1098\/rspb.1972.0019","article-title":"Collagen: ultrastructure and its relation to mechanical properties as a function of aging","volume":"B180","author":"Diament","year":"1972","journal-title":"Proc. Roy. Soc"},{"key":"10.1006\/exer.2001.1057_RF11","series-title":"Principles and Practice of Ophthalmology","article-title":"Corneal transparency","author":"Farell","year":"1994"},{"key":"10.1006\/exer.2001.1057_RF12","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/0014-4835(73)90214-5","article-title":"Studies with the polarization microscope of the fibroblastic activity of the regenerating rabbit's cornea under the influence of corticosteroids","volume":"15","author":"Fran\u00e7ois","year":"1973","journal-title":"Exp. Eye Res."},{"key":"10.1006\/exer.2001.1057_RF13","first-page":"1508","article-title":"Ultrastructuure in anterior and posterior stroma of perfused human and rabbit corneas","volume":"36","author":"Freund","year":"1995","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1006\/exer.2001.1057_RF14","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1001\/archopht.1944.00890040017001","article-title":"Acid-base tolerance of the cornea","volume":"31","author":"Friedenwald","year":"1944","journal-title":"Arch. Ophthalmol."},{"key":"10.1006\/exer.2001.1057_RF15","first-page":"1734","article-title":"Synchrotron X-ray diffraction studies of keratoconous corneal stroma","volume":"33","author":"Fullwood","year":"1992","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1006\/exer.2001.1057_RF16","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1001\/archopht.1955.00930020937019","article-title":"Action of alkalis on the corneal stroma","volume":"54","author":"Grant","year":"1955","journal-title":"Arch. Ophthalmol."},{"key":"10.1006\/exer.2001.1057_RF17","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1002\/jcb.240320108","article-title":"Inhibition of mammalian collagenases by thio-containing peptides","volume":"32","author":"Gray","year":"1986","journal-title":"J. Cell Biochem."},{"key":"10.1006\/exer.2001.1057_RF18","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1073\/pnas.78.2.1176","article-title":"Inhibition of tumor growth, vascularization and collagenolysis of the rabbit cornea by medroxyprogesterone","volume":"78","author":"Gross","year":"1981","journal-title":"Proc. Natl. Acad. Sci., U.S.A."},{"key":"10.1006\/exer.2001.1057_RF19","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1097\/00003226-200003000-00012","article-title":"The keratocyte network of human cornea: a three-dimensional study using confocal laser scanning fluorescence microscopy","volume":"19","author":"Hahnel","year":"2000","journal-title":"Cornea"},{"key":"10.1006\/exer.2001.1057_RF20","article-title":"Interference colour vital imaging: a novel noninvasive microscopic technique","author":"Ho","year":"1993","journal-title":"Microscopy and Analysis"},{"key":"10.1006\/exer.2001.1057_RF21","series-title":"Bioelectrodynamics and Biocommunication","article-title":"Liquid crystalline mesophases in living organisms","author":"Ho","year":"1994"},{"key":"10.1006\/exer.2001.1057_RF22","unstructured":"Huang, Y. F. 1987, Studies on severe alkali-burned rabbit corneas and experimental treatments. MD Thesis. Beijing Postgraduate Medical school"},{"key":"10.1006\/exer.2001.1057_RF23","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1006\/exer.1996.0043","article-title":"Ultrastructural study of the cornea in a bone marrow-transplanted Hurler syndrome patient","volume":"62","author":"Huang","year":"1996","journal-title":"Exp. Eye Res."},{"key":"10.1006\/exer.2001.1057_RF24","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1097\/00003226-199807000-00014","article-title":"Acute calcification in alkali-injured rabbit cornea treated with synthetic inhibitor of matrix metalloproteinases (SIMP)","volume":"17","author":"Huang","year":"1998","journal-title":"Cornea"},{"key":"10.1006\/exer.2001.1057_RF25","first-page":"135","article-title":"The changes of hydroxyproline content in the cornea after alkali burns and the treatment effects","volume":"7","author":"Huang","year":"1989","journal-title":"Chin. Ophthalmic Res."},{"key":"10.1006\/exer.2001.1057_RF26","first-page":"123","article-title":"Fibronectin in aqueous humor and plasma after alkali burns of rabbit cornea","volume":"9","author":"Huang","year":"1991","journal-title":"Chin. Ophthalmic Res."},{"key":"10.1006\/exer.2001.1057_RF27","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/0304-4165(74)90053-1","article-title":"Hormonal regulation of collagen degradation in the uterus: Inhibition of collagenase expression by progesterone and cyclic AMP","volume":"354","author":"Koob","year":"1974","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1006\/exer.2001.1057_RF28","first-page":"986","article-title":"Ascorbic acid prevents corneal ulceration and perforation following experimental alkali burns","volume":"15","author":"Levinson","year":"1976","journal-title":"Invest. Ophthalmol."},{"key":"10.1006\/exer.2001.1057_RF29","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1113\/jphysiol.1957.sp005758","article-title":"The structure and transparency of the cornea","volume":"136","author":"Maurice","year":"1957","journal-title":"J. Physiol."},{"key":"10.1006\/exer.2001.1057_RF30","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/0141-8130(85)90034-0","article-title":"Morphological characterization of tendon development during chick embryogenesis: measurement of birefringence retardation","volume":"7","author":"McBride","year":"1985","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1006\/exer.2001.1057_RF31","series-title":"Scientific Foundations and Clinical Practice","first-page":"422","article-title":"Chemical injuries in the cornea","author":"McCully","year":"1985"},{"key":"10.1006\/exer.2001.1057_RF32","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/S0006-3495(93)81364-X","article-title":"Ultrastructure of the corneal stroma: a comparative study","volume":"64","author":"Meek","year":"1993","journal-title":"Biophys. J."},{"key":"10.1006\/exer.2001.1057_RF33","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1159\/000146862","article-title":"Collagen degradation and mucosal mast cell in endometrium of mouse uterus during early postpartum period","volume":"137","author":"Miyoshi","year":"1990","journal-title":"Acta Anat. Basel."},{"key":"10.1006\/exer.2001.1057_RF34","first-page":"21","article-title":"Prevention by medroxyprogesterone of perforation in the alkali-burned rabbit cornea: Inhibition of collagenolytic activity","volume":"16","author":"Newsome","year":"1977","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1006\/exer.2001.1057_RF35","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1111\/j.1365-2818.1995.tb03667.x","article-title":"Colour-contrast in polarized light microscopy of weakly birefringent biological specimens","volume":"180","author":"Newton","year":"1995","journal-title":"J. Microscopy"},{"key":"10.1006\/exer.2001.1057_RF36","first-page":"677","article-title":"Recombinant tissue inhibitor of metalloproteinases type I suppresses alkali-burn-induced corneal ulceration in rabbits","volume":"35","author":"Paterson","year":"1994","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1006\/exer.2001.1057_RF37","first-page":"157","article-title":"Chemical corneal burns","volume":"24","author":"Pfister","year":"1984","journal-title":"Int. Ophthalmol. Clin."},{"key":"10.1006\/exer.2001.1057_RF38","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1046\/j.1365-2818.1997.2160776.x","article-title":"Quantitative image analysis of birefringent biological material","volume":"187","author":"Ross","year":"1997","journal-title":"J. Microscopy"},{"key":"10.1006\/exer.2001.1057_RF39","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/0014-4835(91)90086-T","article-title":"Collagen metabolism during healing of lacerated rabbit corneas","volume":"52","author":"Sakai","year":"1991","journal-title":"Exp. Eye Res."},{"key":"10.1006\/exer.2001.1057_RF40","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1111\/j.1751-1097.1991.tb09897.x","article-title":"Pathologic analysis of photothermal and photomechanical effects of laser-tissue interactions","volume":"53","author":"Thomsen","year":"1991","journal-title":"Photochem. Photobiol."},{"key":"10.1006\/exer.2001.1057_RF41","first-page":"2174","article-title":"Effect of a metalloproteinase inhibitor on established corneal ulcers after an alkali burn","volume":"33","author":"Wentworth","year":"1992","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1006\/exer.2001.1057_RF43","first-page":"15","article-title":"Polarized light microscopy in biomedical research","volume":"45","author":"Whittaker","year":"1995","journal-title":"Microscopy Anal."},{"key":"10.1006\/exer.2001.1057_RF42","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/S0934-8832(11)80227-1","article-title":"Demonstration of quantitative fabric analysis of tendon collagen using two-dimentional polarized light microscopy","volume":"11","author":"Whittaker","year":"1991","journal-title":"Matrix"},{"key":"10.1006\/exer.2001.1057_RF44","doi-asserted-by":"crossref","first-page":"2145","DOI":"10.1096\/fasebj.5.8.1850705","article-title":"Matrix metalloproteinases and their inhibitors in connective tissue remodeling","volume":"5","author":"Woessner","year":"1991","journal-title":"FASEB"},{"key":"10.1006\/exer.2001.1057_RF45","doi-asserted-by":"crossref","first-page":"207","DOI":"10.3109\/03008208309004857","article-title":"Birefringence of articular cartilage and the distribution of collagen fibril organizations","volume":"11","author":"Yarker","year":"1983","journal-title":"Conn. Tiss. Res."}],"container-title":["Experimental Eye Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014483501910577?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014483501910577?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,5,3]],"date-time":"2021-05-03T03:11:41Z","timestamp":1620011501000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014483501910577"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,10]]},"references-count":45,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2001,10]]}},"alternative-id":["S0014483501910577"],"URL":"https:\/\/doi.org\/10.1006\/exer.2001.1057","relation":{},"ISSN":["0014-4835"],"issn-type":[{"value":"0014-4835","type":"print"}],"subject":[],"published":{"date-parts":[[2001,10]]}}}