{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T08:44:31Z","timestamp":1762159471646},"reference-count":46,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2001,11,1]],"date-time":"2001-11-01T00:00:00Z","timestamp":1004572800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental Eye Research"],"published-print":{"date-parts":[[2001,11]]},"DOI":"10.1006\/exer.2001.1075","type":"journal-article","created":{"date-parts":[[2002,9,16]],"date-time":"2002-09-16T11:46:56Z","timestamp":1032176816000},"page":"669-680","source":"Crossref","is-referenced-by-count":21,"title":["Localization of a Na+-K+-2Cl\u2212 Cotransporter in the Rabbit Lens"],"prefix":"10.1006","volume":"73","author":[{"given":"Lawrence J","family":"Alvarez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oscar A","family":"Candia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helen C","family":"Turner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lee A","family":"Polikoff","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1006\/exer.2001.1075_RF1","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1006\/exer.1994.1041","article-title":"Na+-Cl\u2212-K+ cotransport activity in cultured bovine lens epithelial cells and its absence in intact bovine lenses","volume":"58","author":"Alvarez","year":"1994","journal-title":"Exp. Eye Res."},{"key":"10.1006\/exer.2001.1075_RF2","doi-asserted-by":"crossref","first-page":"143","DOI":"10.3109\/02713688508999980","article-title":"Na+-K+ ATPase distribution in frog and bovine lenses","volume":"4","author":"Alvarez","year":"1985","journal-title":"Curr. Eye Res."},{"key":"10.1006\/exer.2001.1075_RF3","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1016\/0014-4835(92)90179-V","article-title":"Evidence for parallel Na+-H+ and Na+-dependent Cl\u2212-HCO3 exchangers in cultured bovine lens cells","volume":"55","author":"Alvarez","year":"1992","journal-title":"Exp. Eye Res."},{"key":"10.1006\/exer.2001.1075_RF4","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1016\/0014-4835(91)90092-S","article-title":"Contribution from a pH- and tonicity-sensitive K+ conductance to toad translens short-circuit current","volume":"52","author":"Alvarez","year":"1991","journal-title":"Exp. Eye Res."},{"key":"10.1006\/exer.2001.1075_RF5","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1002\/jcp.1041230216","article-title":"Stimulation of bumetanide-sensitive K+ transport in Swiss 3T3 fibroblasts by serum and mitogenic hormones","volume":"123","author":"Amsler","year":"1985","journal-title":"J. Cell. Physiol."},{"key":"10.1006\/exer.2001.1075_RF6","first-page":"727","article-title":"Changes in adhesion complexes define stages in the differentiation of lens fiber cells","volume":"42","author":"Beebe","year":"2001","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1006\/exer.2001.1075_RF7","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1096\/fasebj.10.8.8666170","article-title":"The stimulation of Na,K,Cl cotransport and of system A for neutral amino acid transport is a mechanism for cell volume increase during the cell cycle","volume":"10","author":"Bussolati","year":"1996","journal-title":"FASEB J."},{"key":"10.1006\/exer.2001.1075_RF8","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/0014-4835(73)90122-X","article-title":"Microelectrode and short-circuiting techniques for the study of ion transport in the lens","volume":"15","author":"Candia","year":"1973","journal-title":"Exp. Eye Res."},{"key":"10.1006\/exer.2001.1075_RF9","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1111\/j.1432-0436.1978.tb00941.x","article-title":"Spontaneous transformation of bovine lens epithelial cells: kinetic analysis and differentiation in monolayers and in nude mice","volume":"10","author":"Courtois","year":"1978","journal-title":"Differentation"},{"key":"10.1006\/exer.2001.1075_RF10","doi-asserted-by":"crossref","first-page":"28969","DOI":"10.1074\/jbc.271.46.28969","article-title":"Na:K:2Cl cotransporter (NKCC) of intestinal epithelial cells. Surface expression in response to cAMP","volume":"271","author":"D\u2019Andrea","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1006\/exer.2001.1075_RF11","first-page":"2159","article-title":"Distribution of lens sodium-potassium-adenosine triphosphatase","volume":"34","author":"Delamere","year":"1993","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1006\/exer.2001.1075_RF12","doi-asserted-by":"crossref","first-page":"C515","DOI":"10.1152\/ajpcell.1994.266.2.C515","article-title":"Cell volume and K+ transport during differentiation of mouse erythroleukemia cells","volume":"266","author":"Delpire","year":"1994","journal-title":"Am. J. Physiol."},{"key":"10.1006\/exer.2001.1075_RF13","doi-asserted-by":"crossref","first-page":"357","DOI":"10.3109\/02713689508999933","article-title":"A non-enzymatic method for lens decapsulation which leaves the epithelial cells attached to the fibers","volume":"14","author":"Dewey","year":"1995","journal-title":"Curr. Eye Res."},{"key":"10.1006\/exer.2001.1075_RF14","first-page":"F619","article-title":"Localization and regulation of the rat renal Na(+)-K(+)-2Cl(\u2212) cotransporter, BSC-1","volume":"271","author":"Ecelbarger","year":"1996","journal-title":"Am. J. Physiol."},{"key":"10.1006\/exer.2001.1075_RF15","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1146\/annurev.cb.07.110191.001303","article-title":"Cell cycle regulation in the yeasts Saccharomyces cerevisiae and Schizosaccharomyces pombe","volume":"7","author":"Forsburg","year":"1991","journal-title":"Annu. Rev. Cell Biol."},{"key":"10.1006\/exer.2001.1075_RF16","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1016\/0005-2736(80)90446-0","article-title":"Electrically silent cotransport on Na+, K+ and Cl- Cl\u2212 in Ehrlich cells","volume":"600","author":"Geck","year":"1980","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1006\/exer.2001.1075_RF17","doi-asserted-by":"crossref","first-page":"C869","DOI":"10.1152\/ajpcell.1994.267.4.C869","article-title":"The Na-K-Cl cotransporters","volume":"267","author":"Haas","year":"1994","journal-title":"Am. J. Physiol."},{"key":"10.1006\/exer.2001.1075_RF18","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1023\/A:1020521308985","article-title":"The Na-K-Cl cotransporters","volume":"30","author":"Haas","year":"1998","journal-title":"J. Bioenerg. Biomembr."},{"key":"10.1006\/exer.2001.1075_RF19","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1146\/annurev.physiol.62.1.515","article-title":"The Na-K-Cl cotransporter of secretory epithelia","volume":"62","author":"Haas","year":"2000","journal-title":"Annu. Rev. Physiol."},{"key":"10.1006\/exer.2001.1075_RF20","doi-asserted-by":"crossref","first-page":"C235","DOI":"10.1152\/ajpcell.1983.245.3.C235","article-title":"Bumetanide inhibits (Na+K+2Cl) co-transport at a chloride site","volume":"245","author":"Haas","year":"1983","journal-title":"Am. J. Physiol."},{"key":"10.1006\/exer.2001.1075_RF21","first-page":"F962","article-title":"Hypotonic cell volume regulation in mouse medullary thick ascending limb: effects of ADH","volume":"255","author":"Hebert","year":"1988","journal-title":"Am. J. Physiol."},{"key":"10.1006\/exer.2001.1075_RF22","first-page":"488","article-title":"Basolateral Na(+)-K(+)-2Cl(\u2212) cotransport in cultured and fresh bovine corneal endothelium","volume":"41","author":"Jelamskii","year":"2000","journal-title":"Invest. Ophthalmol. Vis. Sci."},{"key":"10.1006\/exer.2001.1075_RF23","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/0014-4827(65)90285-5","article-title":"A quantitative cytochemical investigation of the relationship between cell mass and initiation of DNA synthesis in mouse fibroblasts in vitro","volume":"40","author":"Killander","year":"1965","journal-title":"Exp. Cell Res."},{"key":"10.1006\/exer.2001.1075_RF24","first-page":"10581","article-title":"Regulation by nerve growth factor and protein phosphorylation of Na\/K\/2Cl cotransport and cell volume in PC12 cells","volume":"269","author":"Leung","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1006\/exer.2001.1075_RF25","first-page":"265","article-title":"Protein measurements with the Folin phenol reagent","volume":"193","author":"Lowry","year":"1951","journal-title":"J. Biol. Chem."},{"key":"10.1006\/exer.2001.1075_RF26","doi-asserted-by":"crossref","first-page":"C1009","DOI":"10.1152\/ajpcell.1992.262.4.C1009","article-title":"Na-K-Cl cotransport in the shark rectal gland. II. Regulation in isolated tubules","volume":"262","author":"Lytle","year":"1992","journal-title":"Am. J. Physiol."},{"key":"10.1006\/exer.2001.1075_RF27","first-page":"25438","article-title":"The Na-K-Cl cotransport protein of shark rectal gland. II. Regulation by direct phosphorylation","volume":"267","author":"Lytle","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1006\/exer.2001.1075_RF28","doi-asserted-by":"crossref","first-page":"C1496","DOI":"10.1152\/ajpcell.1995.269.6.C1496","article-title":"Distribution and diversity of Na-K-Cl cotransport proteins: a study with monoclonal antibodies","volume":"269","author":"Lytle","year":"1995","journal-title":"Am. J. Physiol."},{"key":"10.1006\/exer.2001.1075_RF29","doi-asserted-by":"crossref","first-page":"C1316","DOI":"10.1152\/ajpcell.1993.264.5.C1316","article-title":"Role of Na-K-Cl cotransport in vascular endothelial cell volume regulation","volume":"264","author":"O\u2019Donnell","year":"1993","journal-title":"Am. J. Physiol."},{"key":"10.1006\/exer.2001.1075_RF30","doi-asserted-by":"crossref","first-page":"C1067","DOI":"10.1152\/ajpcell.1995.268.4.C1067","article-title":"Na-K-Cl cotransport regulates intracellular volume and monolayer permeability of trabecular meshwork cells","volume":"268","author":"O\u2019Donnell","year":"1995","journal-title":"Am. J. Physiol."},{"key":"10.1006\/exer.2001.1075_RF31","doi-asserted-by":"crossref","first-page":"C436","DOI":"10.1152\/ajpcell.1992.262.2.C436","article-title":"Regulation of vascular endothelial cell volume by Na-K-2Cl cotransport","volume":"262","author":"O\u2019Neill","year":"1992","journal-title":"Am. J. Physiol."},{"key":"10.1006\/exer.2001.1075_RF32","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1083\/jcb.114.2.337","article-title":"Stimulation of bumetanide-sensitive Na+\/K+\/Cl\u2212 cotransport by different mitogens in synchronized human skin fibroblasts is essential for cell proliferation","volume":"114","author":"Panet","year":"1991","journal-title":"J. Cell Biol."},{"key":"10.1006\/exer.2001.1075_RF33","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1002\/jcp.1041580115","article-title":"Bumetanide and furosemide inhibited vascular endothelial cell proliferation","volume":"158","author":"Panet","year":"1994","journal-title":"J. Cell. Physiol."},{"key":"10.1006\/exer.2001.1075_RF34","first-page":"6177","article-title":"Growth factors activate the bumetanide-sensitive Na+\/K+\/Cl\u2212 cotransport in hamster fibroblasts","volume":"262","author":"Paris","year":"1986","journal-title":"J. Cell Biol."},{"key":"10.1006\/exer.2001.1075_RF35","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/S0014-4835(71)80024-6","article-title":"Chloride concentration and exchange in rabbit lens","volume":"11","author":"Paterson","year":"1971","journal-title":"Exp. Eye Res."},{"key":"10.1006\/exer.2001.1075_RF36","doi-asserted-by":"crossref","first-page":"C173","DOI":"10.1152\/ajpcell.1997.272.1.C173","article-title":"Expression of the Na(+)-K(+)-2Cl(\u2212)cotransporter BSC2 in the nervous system","volume":"272","author":"Plotkin","year":"1997","journal-title":"Am. J. Physiol."},{"key":"10.1006\/exer.2001.1075_RF37","first-page":"458","article-title":"Culturing induced expression of basolateral Na+-K+-2Cl\u2212 cotransporter BSC2 in proximal tubule, aortic endothelium, and vascular smooth muscle","volume":"431","author":"Raat","year":"1996","journal-title":"Pflugers Arch."},{"key":"10.1006\/exer.2001.1075_RF38","doi-asserted-by":"crossref","first-page":"843","DOI":"10.3109\/02713688209020020","article-title":"Localization of steady currents in the lens","volume":"2","author":"Robinson","year":"1982","journal-title":"Curr. Eye Res."},{"key":"10.1006\/exer.2001.1075_RF39","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1126\/science.3018928","article-title":"Early signals in the mitogenic response","volume":"234","author":"Rozengurt","year":"1986","journal-title":"Science"},{"key":"10.1006\/exer.2001.1075_RF40","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1152\/physrev.2000.80.1.211","article-title":"Sodium-potassium-chloride cotransport","volume":"80","author":"Russell","year":"2000","journal-title":"Physiol. Rev."},{"key":"10.1006\/exer.2001.1075_RF41","first-page":"25444","article-title":"The Na-K-Cl cotransporter of avian salt gland. Phosphorylation in response to cAMP-dependent and calcium-dependent secretogogues","volume":"267","author":"Torchia","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1006\/exer.2001.1075_RF42","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1076\/ceyr.21.5.843.5532","article-title":"Immunolocalization of Na-K-ATPase, Na-K-Cl and Na-glucose cotransporters in the conjunctival epithelium","volume":"21","author":"Turner","year":"2000","journal-title":"Curr. Eye Res."},{"key":"10.1006\/exer.2001.1075_RF43","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0014-4835(88)80070-8","article-title":"Equatorial potassium currents in lenses","volume":"46","author":"Wind","year":"1988","journal-title":"Exp. Eye Res."},{"key":"10.1006\/exer.2001.1075_RF44","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1006\/excr.1994.1205","article-title":"Thyroid epithelial morphogenesis in vitro: a role for bumetanide-sensitive Cl\u2212 secretion during follicular lumen development","volume":"213","author":"Yap","year":"1994","journal-title":"Exp. Cell Res."},{"key":"10.1006\/exer.2001.1075_RF45","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1016\/0014-4835(92)90006-E","article-title":"Ca2+\/Na+ exchanger and Na+,K+,2Cl cotransporter in lens fiber plasma membrane vesicles","volume":"55","author":"Ye","year":"1992","journal-title":"Exp. Eye Res."},{"key":"10.1006\/exer.2001.1075_RF46","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1113\/expphysiol.1994.sp003804","article-title":"A new approach to measuring transepithelial potentials in the bovine lens reveals a chloride-dependent component","volume":"79","author":"Zhang","year":"1994","journal-title":"Exp. Physiol."}],"container-title":["Experimental Eye Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014483501910759?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014483501910759?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,12,16]],"date-time":"2019-12-16T01:12:40Z","timestamp":1576458760000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014483501910759"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,11]]},"references-count":46,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2001,11]]}},"alternative-id":["S0014483501910759"],"URL":"https:\/\/doi.org\/10.1006\/exer.2001.1075","relation":{},"ISSN":["0014-4835"],"issn-type":[{"value":"0014-4835","type":"print"}],"subject":[],"published":{"date-parts":[[2001,11]]}}}