{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T08:44:32Z","timestamp":1762159472908},"reference-count":58,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2000,5,1]],"date-time":"2000-05-01T00:00:00Z","timestamp":957139200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental Neurology"],"published-print":{"date-parts":[[2000,5]]},"DOI":"10.1006\/exnr.2000.7366","type":"journal-article","created":{"date-parts":[[2002,9,16]],"date-time":"2002-09-16T11:46:56Z","timestamp":1032176816000},"page":"191-199","source":"Crossref","is-referenced-by-count":34,"title":["125I-CGP 64213 Binding to GABAB Receptors in the Brain of Monkeys: Effect of MPTP and Dopaminomimetic Treatments"],"prefix":"10.1006","volume":"163","author":[{"given":"Fr\u00e9d\u00e9ric","family":"Calon","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marc","family":"Morissette","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Goulet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Grondin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pierre J.","family":"Blanchet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul J.","family":"B\u00e9dard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Th\u00e9r\u00e8se","family":"Di Paolo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1006\/exnr.2000.7366_RF1","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/0006-8993(91)91258-3","article-title":"Excitatory and inhibitory amino acid binding sites in human dentate nucleus","volume":"560","author":"Albin","year":"1991","journal-title":"Brain Res."},{"key":"10.1006\/exnr.2000.7366_RF2","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/0166-2236(89)90074-X","article-title":"The functional anatomy of basal ganglia disorders","volume":"12","author":"Albin","year":"1989","journal-title":"Trends Neurosci."},{"key":"10.1006\/exnr.2000.7366_RF3","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/S0959-4388(98)80059-7","article-title":"GABAB receptors: Drugs meet clones","volume":"8","author":"Bettler","year":"1998","journal-title":"Curr. Opin. Neurobiol."},{"key":"10.1006\/exnr.2000.7366_RF4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/(SICI)1096-9861(19990913)412:1<1::AID-CNE1>3.0.CO;2-D","article-title":"Spatial distribution of GABA(B)R1 receptor mRNA and binding sites in the rat brain","volume":"412","author":"Bischoff","year":"1999","journal-title":"J. Comp. Neurol."},{"key":"10.1006\/exnr.2000.7366_RF5","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/0165-6147(93)90056-P","article-title":"GABAB receptor antagonists: From synthesis to therapeutic applications","volume":"14","author":"Bittiger","year":"1993","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1006\/exnr.2000.7366_RF6","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1111\/j.1476-5381.1996.tb15493.x","article-title":"Electrophysiological actions of GABAB agonists and antagonists in rat dorso-lateral septal neurones in vitro","volume":"118","author":"Bon","year":"1996","journal-title":"Br. J. Pharmacol."},{"key":"10.1006\/exnr.2000.7366_RF7","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1111\/j.1476-5381.1987.tb09004.x","article-title":"Coexistence of carriers for dopamine and GABA uptake on a same nerve terminal in the rat brain","volume":"91","author":"Bonanno","year":"1987","journal-title":"Br. J. Pharmacol."},{"key":"10.1006\/exnr.2000.7366_RF8","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1146\/annurev.pa.33.040193.000545","article-title":"GABAB receptor pharmacology","volume":"33","author":"Bowery","year":"1993","journal-title":"Annu. Rev. Pharmacol. Toxicol."},{"key":"10.1006\/exnr.2000.7366_RF9","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/0306-4522(87)90098-4","article-title":"GABAA and GABAB receptor site distribution in the rat central nervous system","volume":"20","author":"Bowery","year":"1987","journal-title":"Neuroscience"},{"key":"10.1006\/exnr.2000.7366_RF10","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/0006-8993(95)00229-J","article-title":"Levodopa or D2 agonist induced dyskinesia in MPTP monkeys: Correlation with changes in dopamine and GABAA receptors in the striatopallidal complex","volume":"680","author":"Calon","year":"1995","journal-title":"Brain Res."},{"key":"10.1006\/exnr.2000.7366_RF11","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S0197-0186(99)00064-9","article-title":"Chronic D1 and D2 dopaminomimetic treatment of MPTP-denervated monkeys: Effects on basal ganglia GABAA\/benzodiazepine receptor complex and GABA content","volume":"35","author":"Calon","year":"1999","journal-title":"Neurochem. Int."},{"key":"10.1006\/exnr.2000.7366_RF12","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/0306-4522(90)90144-S","article-title":"Distribution and kinetics of GABAB binding sites in rat central nervous system: a quantitative autoradiographic study","volume":"34","author":"Chu","year":"1990","journal-title":"Neuroscience"},{"key":"10.1006\/exnr.2000.7366_RF13","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/0304-3940(87)90264-3","article-title":"Quantitative autoradiography of hippocampal GABAB and GABAA receptor changes in Alzheimer's disease","volume":"82","author":"Chu","year":"1987","journal-title":"Neurosci. Lett."},{"key":"10.1006\/exnr.2000.7366_RF14","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/0166-2236(90)90110-V","article-title":"Primate models of movement disorders of basal ganglia origin","volume":"13","author":"DeLong","year":"1990","journal-title":"Trends Neurosci."},{"key":"10.1006\/exnr.2000.7366_RF15","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1007\/s007020050166","article-title":"Activation of nigral dopamine neurons by the selective GABA(B)-receptor antagonist SCH 50911","volume":"106","author":"Erhardt","year":"1999","journal-title":"J. Neural Transm."},{"key":"10.1006\/exnr.2000.7366_RF16","doi-asserted-by":"crossref","first-page":"3313","DOI":"10.1021\/jm00017a016","article-title":"Phosphinic acid analogues of GABA. 2. Selective, orally active GABAB antagonists","volume":"38","author":"Froestl","year":"1995","journal-title":"J. Med. Chem."},{"key":"10.1006\/exnr.2000.7366_RF17","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/0304-3940(85)90126-0","article-title":"gamma-Aminobutyric acidB receptors in the rat brain: Quantitative autoradiographic localization using [3H](\u2212)-baclofen","volume":"56","author":"Gehlert","year":"1985","journal-title":"Neurosci. Lett."},{"key":"10.1006\/exnr.2000.7366_RF18","first-page":"43","article-title":"The neostriatal mosaic: Multiple levels of compartmental organization","volume":"36","author":"Gerfen","year":"1992","journal-title":"J. Neural Transm. Suppl."},{"key":"10.1006\/exnr.2000.7366_RF19","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/0306-4522(93)90014-7","article-title":"Chronic continuous and intermittent l-3,4-dihydroxyphenylalanine treatments differentially affect basal ganglia function in 6-hydroxydopamine lesioned rats\u2014An autoradiographic study using [3H]flunitrazepam","volume":"57","author":"Gnanalingham","year":"1993","journal-title":"Neuroscience"},{"key":"10.1006\/exnr.2000.7366_RF20","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1002\/mds.870080205","article-title":"Effect of adding the D1 agonist CY 208\u2013243 to chronic bromocriptine treatment. I: Evaluation of motor parameters in relation to striatal catecholamine content and dopamine receptors","volume":"8","author":"Gomez-Mancilla","year":"1993","journal-title":"Mov. Disord."},{"key":"10.1006\/exnr.2000.7366_RF21","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/0006-8993(96)00157-6","article-title":"Dyskinesias and tolerance induced by chronic treatment with a D1 agonist administered in pulsatile or continuous mode do not correlate with changes of putaminal D1 receptors in drug-naive MPTP monkeys","volume":"719","author":"Goulet","year":"1996","journal-title":"Brain Res."},{"key":"10.1006\/exnr.2000.7366_RF22","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1002\/(SICI)1098-2396(19990601)32:3<153::AID-SYN2>3.0.CO;2-X","article-title":"Neurotensin receptors and dopamine transporters: Effects of MPTP lesioning and chronic dopaminergic treatments in monkeys","volume":"32","author":"Goulet","year":"1999","journal-title":"Synapse"},{"key":"10.1006\/exnr.2000.7366_RF23","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1097\/00002826-199208000-00002","article-title":"Baclofen in the treatment of dystonia","volume":"15","author":"Greene","year":"1992","journal-title":"Clin. Neuropharmacol."},{"key":"10.1006\/exnr.2000.7366_RF24","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/0006-8993(96)00597-5","article-title":"Cabergoline, a long-acting dopamine D2-like receptor agonist, produces a sustained antiparkinsonian effect with transient dyskinesias in parkinsonian drug-naive primates","volume":"735","author":"Grondin","year":"1996","journal-title":"Brain Res."},{"key":"10.1006\/exnr.2000.7366_RF25","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1002\/cne.903040406","article-title":"Organization of striatopallidal, striatonigral, and nigrostriatal projections in the macaque","volume":"304","author":"Hedreen","year":"1991","journal-title":"J. Comp. Neurol."},{"key":"10.1006\/exnr.2000.7366_RF26","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1523\/JNEUROSCI.02-08-01129.1982","article-title":"Light microscopic localization of brain opiate receptors: A general autoradiographic method which preserves tissue quality","volume":"2","author":"Herkenham","year":"1982","journal-title":"J. Neurosci."},{"key":"10.1006\/exnr.2000.7366_RF27","series-title":"Handbook of Experimental Pharmacology","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/978-3-642-73899-9_6","article-title":"The neurochemical basis of the pharmacology of Parkinson's disease","author":"Hornykiewicz","year":"1989"},{"key":"10.1006\/exnr.2000.7366_RF28","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1006\/bbrc.1998.9706","article-title":"Cloning and tissue distribution of novel splice variants of the rat GABAB receptor","volume":"253","author":"Isomoto","year":"1998","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1006\/exnr.2000.7366_RF29","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1038\/25348","article-title":"GABA(B) receptors function as a heteromeric assembly of the subunits GABA(B)R1 and GABA(B)R2","volume":"396","author":"Jones","year":"1998","journal-title":"Nature"},{"key":"10.1006\/exnr.2000.7366_RF30","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1038\/386239a0","article-title":"Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors","volume":"386","author":"Kaupmann","year":"1997","journal-title":"Nature"},{"key":"10.1006\/exnr.2000.7366_RF31","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1038\/25360","article-title":"GABA(B)-receptor subtypes assemble into functional heteromeric complexes","volume":"396","author":"Kaupmann","year":"1998","journal-title":"Nature"},{"key":"10.1006\/exnr.2000.7366_RF32","doi-asserted-by":"crossref","first-page":"14991","DOI":"10.1073\/pnas.95.25.14991","article-title":"Human gamma-aminobutyric acid type B receptors are differentially expressed and regulate inwardly rectifying K+ channels","volume":"95","author":"Kaupmann","year":"1998","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1006\/exnr.2000.7366_RF33","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1126\/science.283.5398.74","article-title":"Role of heteromer formation in GABAB receptor function","volume":"283","author":"Kuner","year":"1999","journal-title":"Science"},{"key":"10.1006\/exnr.2000.7366_RF34","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1136\/jnnp.41.8.707","article-title":"Baclofen in Parkinson's disease","volume":"41","author":"Lees","year":"1978","journal-title":"J. Neurol. Neurosurg. Psychiatry"},{"key":"10.1006\/exnr.2000.7366_RF35","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/0006-8993(77)90540-6","article-title":"Distribution of high affinity sodium-independent [3H]gamma-aminobutyric acid [3H]GABA binding in the human brain: Alterations in Parkinson's disease","volume":"127","author":"Lloyd","year":"1977","journal-title":"Brain Res."},{"key":"10.1006\/exnr.2000.7366_RF36","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1006\/mcne.1998.0698","article-title":"Developmental changes of agonist affinity at GABABR1 receptor variants in rat brain","volume":"12","author":"Malitschek","year":"1998","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1006\/exnr.2000.7366_RF37","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1002\/(SICI)1096-9861(19990315)405:3<299::AID-CNE2>3.0.CO;2-6","article-title":"Immunohistochemical localization of GABA(B) receptors in the rat central nervous system","volume":"405","author":"Margeta-Mitrovic","year":"1999","journal-title":"J. Comp. Neurol."},{"key":"10.1006\/exnr.2000.7366_RF38","first-page":"225","article-title":"GABA and movement disorders","volume":"30","author":"Marsden","year":"1981","journal-title":"Adv. Biochem. Psychopharmacol."},{"key":"10.1006\/exnr.2000.7366_RF39","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/0306-4522(94)00484-M","article-title":"Activity of pallidal neurons in the monkey during dyskinesia induced by injection of bicuculline in the external pallidum","volume":"65","author":"Matsumura","year":"1995","journal-title":"Neuroscience"},{"key":"10.1006\/exnr.2000.7366_RF40","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0165-6147(99)01323-1","article-title":"GABAB receptors make it to the top\u2014As dimers","volume":"20","author":"Mohler","year":"1999","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1006\/exnr.2000.7366_RF41","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0074-7742(08)60304-9","article-title":"The pharmacology and function of central GABAB receptors","volume":"36","author":"Mott","year":"1994","journal-title":"Int. Rev. Neurobiol."},{"key":"10.1006\/exnr.2000.7366_RF42","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1002\/(SICI)1096-9861(19980427)394:1<118::AID-CNE9>3.0.CO;2-3","article-title":"GABA(B) receptor gene expression in monkey thalamus","volume":"394","author":"Munoz","year":"1998","journal-title":"J. Comp. Neurol."},{"key":"10.1006\/exnr.2000.7366_RF43","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1001\/archneur.1980.00500520030003","article-title":"Dystonic foot response of Parkinsonism","volume":"37","author":"Nausieda","year":"1980","journal-title":"Arch. Neurol."},{"key":"10.1006\/exnr.2000.7366_RF44","doi-asserted-by":"crossref","first-page":"7607","DOI":"10.1074\/jbc.274.12.7607","article-title":"Identification of a GABAB receptor subunit, gb2, required for functional GABAB receptor activity","volume":"274","author":"Ng","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1006\/exnr.2000.7366_RF45","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1212\/WNL.40.2.340","article-title":"Levodopa-induced dyskinesia: Review, observations, and speculations","volume":"40","author":"Nutt","year":"1990","journal-title":"Neurology"},{"key":"10.1006\/exnr.2000.7366_RF46","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/S0969-8051(98)00066-3","article-title":"Functional neuroanatomy of the basal ganglia as studied by dual-probe microdialysis","volume":"25","author":"O'Connor","year":"1998","journal-title":"Nucl. Med. Biol."},{"key":"10.1006\/exnr.2000.7366_RF47","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1212\/WNL.50.3_Suppl_3.S1","article-title":"An algorithm (decision tree) for the management of Parkinson's disease: treatment guidelines. American Academy of Neurology","volume":"50","author":"Olanow","year":"1998","journal-title":"Neurology"},{"key":"10.1006\/exnr.2000.7366_RF48","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/0014-2999(77)90012-7","article-title":"Rotational behavior induced in rats by intranigral application of GABA-related drugs and GABA antagonists","volume":"45","author":"Olpe","year":"1977","journal-title":"Eur. J. Pharmacol."},{"key":"10.1006\/exnr.2000.7366_RF49","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.1111\/j.1471-4159.1985.tb07205.x","article-title":"Gamma-aminobutyric acid and benzodiazepine receptor changes induced by unilateral 6-hydroxydopamine lesions of the medial forebrain bundle","volume":"45","author":"Pan","year":"1985","journal-title":"J. Neurochem."},{"key":"10.1006\/exnr.2000.7366_RF50","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/0301-0082(95)80010-6","article-title":"Chemical anatomy of primate basal ganglia","volume":"46","author":"Parent","year":"1995","journal-title":"Prog. Neurobiol."},{"key":"10.1006\/exnr.2000.7366_RF51","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/0165-0173(94)00007-C","article-title":"Functional anatomy of the basal ganglia. I. The cortico\u2013basal ganglia\u2013thalamo\u2013cortical loop","volume":"20","author":"Parent","year":"1995","journal-title":"Brain Res. Brain Res. Rev."},{"key":"10.1006\/exnr.2000.7366_RF52","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/0306-4522(92)90096-K","article-title":"D1 and D2 dopamine receptors differentially regulate c-fos expression in striatonigral and striatopallidal neurons","volume":"49","author":"Robertson","year":"1992","journal-title":"Neuroscience"},{"key":"10.1006\/exnr.2000.7366_RF53","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/0006-8993(90)90762-Z","article-title":"The role of striatopallidal neurones utilizing gamma-aminobutyric acid in the pathophysiology of MPTP-induced parkinsonism in the primate: Evidence from [3H]flunitrazepam autoradiography","volume":"531","author":"Robertson","year":"1990","journal-title":"Brain Res."},{"key":"10.1006\/exnr.2000.7366_RF54","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1111\/j.1476-5381.1993.tb13647.x","article-title":"In vivo release of dopamine from rat striatum, substantia nigra and prefrontal cortex: Differential modulation by baclofen","volume":"109","author":"Santiago","year":"1993","journal-title":"Br. J. Pharmacol."},{"key":"10.1006\/exnr.2000.7366_RF55","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1002\/cne.902220208","article-title":"A stereotaxic atlas of the brain of the cynomolgus monkey (Macaca fascicularis)","volume":"222","author":"Szabo","year":"1984","journal-title":"J. Comp. Neurol."},{"key":"10.1006\/exnr.2000.7366_RF56","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1016\/0278-5846(95)00132-F","article-title":"D1\/D2 actions of dopaminergic drugs studied with [14C]-2-deoxyglucose autoradiography","volume":"19","author":"Trugman","year":"1995","journal-title":"Prog. Neuropsychopharmacol. Biol. Psychiatry"},{"key":"10.1006\/exnr.2000.7366_RF57","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1007\/BF00168947","article-title":"Systemic administration of baclofen and the GABAB antagonist, CGP 35348, does not affect GABA, glutamate or aspartate in microdialysates of the striatum of conscious rats","volume":"345","author":"Waldmeier","year":"1992","journal-title":"Naunyn Schmiedebergs Arch. Pharmacol."},{"key":"10.1006\/exnr.2000.7366_RF58","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0304-3940(94)91039-1","article-title":"Do nerve terminals and cell bodies of nigrostriatal dopaminergic neurons of the rat contain similar receptors?","volume":"167","author":"Westerink","year":"1994","journal-title":"Neurosci. Lett."}],"container-title":["Experimental Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014488600973667?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014488600973667?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,12,16]],"date-time":"2019-12-16T04:11:48Z","timestamp":1576469508000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014488600973667"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,5]]},"references-count":58,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2000,5]]}},"alternative-id":["S0014488600973667"],"URL":"https:\/\/doi.org\/10.1006\/exnr.2000.7366","relation":{},"ISSN":["0014-4886"],"issn-type":[{"value":"0014-4886","type":"print"}],"subject":[],"published":{"date-parts":[[2000,5]]}}}