{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T13:44:00Z","timestamp":1791899040200,"version":"4.3.4"},"reference-count":26,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2001,5,1]],"date-time":"2001-05-01T00:00:00Z","timestamp":988675200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental Neurology"],"published-print":{"date-parts":[[2001,5]]},"DOI":"10.1006\/exnr.2001.7644","type":"journal-article","created":{"date-parts":[[2002,9,16]],"date-time":"2002-09-16T15:46:56Z","timestamp":1032191216000},"page":"23-29","source":"Crossref","is-referenced-by-count":56,"title":["Diminished Survival of Mesencephalic Dopamine Neurons Grafted into Aged Hosts Occurs during the Immediate Postgrafting Interval"],"prefix":"10.1006","volume":"169","author":[{"given":"Caryl E.","family":"Sortwell","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria D.","family":"Camargo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark R.","family":"Pitzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandeep","family":"Gyawali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy J.","family":"Collier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1006\/exnr.2001.7644_RF1","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1002\/ar.1090940210","article-title":"Estimation of nuclear populations from microtome sections","volume":"94","author":"Abercrombie","year":"1946","journal-title":"Anat. Rec."},{"key":"10.1006\/exnr.2001.7644_RF2","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1006\/exnr.1996.0141","article-title":"The time course of cell loss of dopaminergic neurons and the gliotic reaction surrounding grafts of embryonic mesencephalon to the striatum","volume":"141","author":"Barker","year":"1996","journal-title":"Exp. Neurol."},{"key":"10.1006\/exnr.2001.7644_RF3","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/0197-4580(89)90048-1","article-title":"Progressive failure of cerebral angiogenesis supporting neural plasticity in aging rats","volume":"10","author":"Black","year":"1989","journal-title":"Neurobiol. Aging"},{"key":"10.1006\/exnr.2001.7644_RF4","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1002\/cne.902600105","article-title":"Angioarchitecture of the CNS, pituitary gland, and intercerebral grafts revealed with peroxidase cytochemistry","volume":"260","author":"Broadwell","year":"1987","journal-title":"J. Comp. Neurol."},{"key":"10.1006\/exnr.2001.7644_RF5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0014-4886(91)90110-X","article-title":"Allografts of CNS tissue possess a blood-brain barrier. II. Angiogenesis in solid tissue and cell suspension graft","volume":"112","author":"Broadwell","year":"1991","journal-title":"Exp. Neurol."},{"key":"10.1006\/exnr.2001.7644_RF6","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/S0079-6123(08)61832-4","article-title":"Survival, growth and function of dopaminergic neurons grafted to the brain","volume":"71","author":"Brundin","year":"1987","journal-title":"Prog. Brain Res."},{"key":"10.1006\/exnr.2001.7644_RF7","doi-asserted-by":"crossref","first-page":"5563","DOI":"10.1523\/JNEUROSCI.19-13-05563.1999","article-title":"Diminished viability, growth, and behavioral efficacy of fetal dopamine neuron grafts in aging rats with long-term dopamine depletion: An argument for neurotrophic supplementation","volume":"19","author":"Collier","year":"1999","journal-title":"J. Neurosci."},{"key":"10.1006\/exnr.2001.7644_RF8","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1111\/j.1460-9568.1990.tb00419.x","article-title":"Effect of prior dopamine denervation on survival and fiber outgrowth from intrastriatal fetal mesencephalic grafts","volume":"2","author":"Doucet","year":"1990","journal-title":"Eur. J. Neurosci."},{"key":"10.1006\/exnr.2001.7644_RF9","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1007\/BF00242009","article-title":"Temporal pattern of host responses against intrastriatal grafts of syngeneic, allogeneic or xenogeneic embryonic neuronal tissue in rats","volume":"104","author":"Duan","year":"1995","journal-title":"Exp. Brain Res."},{"key":"10.1006\/exnr.2001.7644_RF10","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/0165-3806(89)90077-1","article-title":"Vascularization of fetal cell suspension grafts in the excitotoxically lesioned adult rat thalamus","volume":"48","author":"Dusart","year":"1989","journal-title":"Brain Res. Dev. Brain Res."},{"key":"10.1006\/exnr.2001.7644_RF11","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1006\/exnr.1999.7198","article-title":"Patterns of cell death and dopaminergic neuron survival in intrastriatal nigral grafts","volume":"160","author":"Emg\u00e5rd","year":"1999","journal-title":"Exp. Neurol."},{"key":"10.1006\/exnr.2001.7644_RF12","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1007\/BF00241123","article-title":"Dopaminergic neuronal survival and the effects of bFGF in explant, three dimensional and monolayer cultures of embryonic rat ventral mesencephalon","volume":"106","author":"Fawcett","year":"1995","journal-title":"Exp. Brain Res."},{"key":"10.1006\/exnr.2001.7644_RF13","article-title":"Double-blind controlled trial of human embryonic dopamine cell transplants in advanced Parkinson's disease","author":"Freed","year":"1999","journal-title":"Am. Soc. Neur. Trans. Rep. Abstr."},{"key":"10.1006\/exnr.2001.7644_RF14","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1083\/jcb.119.3.493","article-title":"Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation","volume":"119","author":"Gavrieli","year":"1992","journal-title":"J. Cell Biol."},{"key":"10.1006\/exnr.2001.7644_RF15","doi-asserted-by":"crossref","first-page":"1118","DOI":"10.1056\/NEJM199504273321702","article-title":"Neuropathological evidence of graft survival and striatal reinnervation after the transplantation of fetal mesencephalic tissue in a patient with Parkinson's disease [see comments]","volume":"332","author":"Kordower","year":"1995","journal-title":"N. Engl. J. Med."},{"key":"10.1006\/exnr.2001.7644_RF16","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1002\/(SICI)1096-9861(19960624)370:2<203::AID-CNE6>3.0.CO;2-6","article-title":"Functional fetal nigral grafts in a patient with Parkinson's disease: Chemoanatomic, ultrastructural, and metabolic studies","volume":"370","author":"Kordower","year":"1996","journal-title":"J. Comp. Neurol."},{"key":"10.1006\/exnr.2001.7644_RF17","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1002\/cne.902710304","article-title":"Patterns of angiogenesis in neural transplant models. II. Fetal neocortical transplants","volume":"271","author":"Krum","year":"1988","journal-title":"J. Comp. Neurol."},{"key":"10.1006\/exnr.2001.7644_RF18","doi-asserted-by":"crossref","first-page":"272","DOI":"10.3171\/jns.1994.81.2.0272","article-title":"Vascularization and microvascular permeability in solid versus cell-suspension embryonic neural grafts","volume":"81","author":"Leigh","year":"1994","journal-title":"J. Neurosurg."},{"key":"10.1006\/exnr.2001.7644_RF19","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/S0006-8993(00)01945-4","article-title":"Striatal trophic activity is reduced in the aged rat brain","volume":"856","author":"Ling","year":"2000","journal-title":"Brain Res."},{"key":"10.1006\/exnr.2001.7644_RF20","first-page":"102","article-title":"Fetal nigral transplantation as a therapy for Parkinson's disease","volume":"19","author":"Olanow","year":"1996","journal-title":"TINS"},{"key":"10.1006\/exnr.2001.7644_RF21","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1002\/(SICI)1097-4644(20000401)77:1<116::AID-JCB12>3.0.CO;2-7","article-title":"A deficit in collagenase activity contributes to impaired migration of aged microvascular endothelial cells","volume":"77","author":"Reed","year":"2000","journal-title":"J. Cell Biochem."},{"key":"10.1006\/exnr.2001.7644_RF22","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1083\/jcb.15.1.73","article-title":"Localized areas of high alkaline phosphatase activity in the terminal arterial tree","volume":"15","author":"Romanul","year":"1962","journal-title":"J. Cell Biol."},{"key":"10.1006\/exnr.2001.7644_RF23","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1006\/exnr.2000.7476","article-title":"Time course of apoptotic cell death within mesencephalic cell suspension grafts: Implications for improving grafted dopamine neuron survival","volume":"165","author":"Sortwell","year":"2000","journal-title":"Exp. Neurol."},{"key":"10.1006\/exnr.2001.7644_RF24","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1002\/(SICI)1096-9861(19981005)399:4<530::AID-CNE6>3.0.CO;2-2","article-title":"Co-grafted embryonic striatum increases the survival of grafted embryonic dopamine neurons","volume":"399","author":"Sortwell","year":"1998","journal-title":"J. Comp. Neurol."},{"key":"10.1006\/exnr.2001.7644_RF25","first-page":"1479","article-title":"Impaired wound repair and delayed angiogenesis in aged mice","volume":"79","author":"Swift","year":"1999","journal-title":"Lab. Invest."},{"key":"10.1006\/exnr.2001.7644_RF26","first-page":"264","article-title":"Border zone neovascularization in cerebral ischemic infarct","volume":"37","author":"Szpak","year":"1999","journal-title":"Folia. Neuropathol."}],"container-title":["Experimental Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014488601976447?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014488601976447?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,12,16]],"date-time":"2019-12-16T23:54:07Z","timestamp":1576540447000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014488601976447"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,5]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2001,5]]}},"alternative-id":["S0014488601976447"],"URL":"https:\/\/doi.org\/10.1006\/exnr.2001.7644","relation":{},"ISSN":["0014-4886"],"issn-type":[{"value":"0014-4886","type":"print"}],"subject":[],"published":{"date-parts":[[2001,5]]}}}