{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T22:21:04Z","timestamp":1791066064834,"version":"4.1.0"},"reference-count":23,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2001,6,1]],"date-time":"2001-06-01T00:00:00Z","timestamp":991353600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental Neurology"],"published-print":{"date-parts":[[2001,6]]},"DOI":"10.1006\/exnr.2001.7677","type":"journal-article","created":{"date-parts":[[2002,9,16]],"date-time":"2002-09-16T11:46:56Z","timestamp":1032176816000},"page":"386-391","source":"Crossref","is-referenced-by-count":190,"title":["Pro- and Anti-inflammatory Cytokine Gene Expression in Rat Sciatic Nerve Chronic Constriction Injury Model of Neuropathic Pain"],"prefix":"10.1006","volume":"169","author":[{"given":"Kunihisa","family":"Okamoto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David P.","family":"Martin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James D.","family":"Schmelzer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoshiyuki","family":"Mitsui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phillip A.","family":"Low","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1006\/exnr.2001.7677_RF1","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/0304-3959(88)90209-6","article-title":"A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man","volume":"33","author":"Bennett","year":"1988","journal-title":"Pain"},{"key":"10.1006\/exnr.2001.7677_RF2","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1084\/jem.174.6.1549","article-title":"Macrophage deactivation by interleukin 10","volume":"174","author":"Bogdan","year":"1991","journal-title":"J. Exp. Med."},{"key":"10.1006\/exnr.2001.7677_RF3","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1046\/j.1471-4159.1995.64020850.x","article-title":"Interleukin-6 production by Schwann cells and induction in sciatic nerve injury","volume":"64","author":"Bolin","year":"1995","journal-title":"J. Neurochem."},{"key":"10.1006\/exnr.2001.7677_RF4","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/0304-3940(94)11154-B","article-title":"Role of peri-axonal inflammation in the development of thermal hyperalgesia and guarding behavior in a rat model of neuropathic pain","volume":"184","author":"Clatworthy","year":"1995","journal-title":"Neurosci. Lett."},{"key":"10.1006\/exnr.2001.7677_RF5","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1111\/j.1749-6632.1997.tb48386.x","article-title":"Microvascular responses to cerebral ischemia\/inflammation","volume":"823","author":"Del Zoppo","year":"1997","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1006\/exnr.2001.7677_RF6","doi-asserted-by":"crossref","first-page":"9","DOI":"10.2165\/00003495-199754010-00002","article-title":"Trends and future developments in the pharmacological treatment of acute ischaemic stroke","volume":"54","author":"Del Zoppo","year":"1997","journal-title":"Drugs"},{"key":"10.1006\/exnr.2001.7677_RF7","doi-asserted-by":"crossref","first-page":"3815","DOI":"10.4049\/jimmunol.147.11.3815","article-title":"IL-10 inhibits cytokine production by activated macrophages","volume":"147","author":"Fiorentino","year":"1991","journal-title":"J. Immunol."},{"key":"10.1006\/exnr.2001.7677_RF8","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1056\/NEJM199707173370310","article-title":"Anticytokine therapy in rheumatoid arthritis","volume":"337","author":"Firestein","year":"1997","journal-title":"N. Engl. J. Med."},{"key":"10.1006\/exnr.2001.7677_RF9","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/0165-0270(93)90109-5","article-title":"A system to measure thermal nociception","volume":"49","author":"Galbraith","year":"1993","journal-title":"J. Neurosci. Methods"},{"key":"10.1006\/exnr.2001.7677_RF10","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1006\/exnr.1999.7193","article-title":"Serial determination of tumor necrosis factor-alpha content in rat sciatic nerve after chronic constriction injury","volume":"160","author":"George","year":"1999","journal-title":"Exp. Neurol."},{"key":"10.1006\/exnr.2001.7677_RF11","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/0304-3959(88)90026-7","article-title":"A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia","volume":"32","author":"Hargreaves","year":"1988","journal-title":"Pain"},{"key":"10.1006\/exnr.2001.7677_RF12","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1038\/330658a0","article-title":"Interleukin-1 regulates synthesis of nerve growth factor in non-neuronal cells of rat sciatic nerve","volume":"330","author":"Lindholm","year":"1987","journal-title":"Nature"},{"key":"10.1006\/exnr.2001.7677_RF13","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/0304-3959(93)90100-4","article-title":"Possible chemical contribution from chromic gut sutures produces disorders of pain sensation like those seen in man","volume":"54","author":"Maves","year":"1993","journal-title":"Pain"},{"key":"10.1006\/exnr.2001.7677_RF14","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/S0006-8993(99)01830-2","article-title":"The expression of proinflammatory cytokine mRNA in the sciatic-tibial nerve of ischemia\u2013reperfusion injury","volume":"844","author":"Mitsui","year":"1999","journal-title":"Brain Res."},{"key":"10.1006\/exnr.2001.7677_RF15","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1111\/j.1476-5381.1995.tb14987.x","article-title":"Cytokine-mediated inflammatory hyperalgesia limited by interleukin-10","volume":"115","author":"Poole","year":"1995","journal-title":"Br. J. Pharmacol."},{"key":"10.1006\/exnr.2001.7677_RF16","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/0165-5728(92)90176-L","article-title":"Interleukin-1 activity in lesioned peripheral nerve","volume":"39","author":"Rotshenker","year":"1992","journal-title":"J. Neuroimmunol."},{"key":"10.1006\/exnr.2001.7677_RF17","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1007\/s004010050583","article-title":"Chronic constriction model of rat sciatic nerve: Nerve blood flow, morphologic and biochemical alterations","volume":"93","author":"Sasaki","year":"1997","journal-title":"Acta Neuropathol."},{"key":"10.1006\/exnr.2001.7677_RF18","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0304-3959(97)00154-1","article-title":"The effect of thalidomide treatment on vascular pathology and hyperalgesia caused by chronic constriction injury of rat nerve","volume":"74","author":"Sommer","year":"1998","journal-title":"Pain"},{"key":"10.1006\/exnr.2001.7677_RF19","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/0304-3959(94)90013-2","article-title":"Extra-territorial pain in rats with a peripheral mononeuropathy: Mechano-allodynia in the territory of an uninjured nerve","volume":"57","author":"Tal","year":"1994","journal-title":"Pain"},{"key":"10.1006\/exnr.2001.7677_RF20","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S0304-3959(97)00148-6","article-title":"Anti-inflammatory interleukin-10 therapy in CCI neuropathy decreases thermal hyperalgesia, macrophage recruitment, and endoneurial TNF-alpha expression","volume":"74","author":"Wagner","year":"1998","journal-title":"Pain"},{"key":"10.1006\/exnr.2001.7677_RF21","doi-asserted-by":"crossref","first-page":"2897","DOI":"10.1097\/00001756-199611250-00018","article-title":"Endoneurial injection of TNF-\u03b1 produces neuropathic pain behaviors","volume":"7","author":"Wagner","year":"1996","journal-title":"NeuroReport"},{"key":"10.1006\/exnr.2001.7677_RF22","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/0165-5728(92)90260-R","article-title":"Changes in plasma cytokines associated with peripheral nerve injury","volume":"39","author":"Wells","year":"1992","journal-title":"J. Neuroimmunol."},{"key":"10.1006\/exnr.2001.7677_RF23","first-page":"1492","article-title":"Peripheral neuropeptide plasticity in a quadruple ligature model of painful neuropathy","volume":"21","author":"Zollman","year":"1995","journal-title":"Soc. Neurosci."}],"container-title":["Experimental Neurology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014488601976770?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0014488601976770?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T22:16:52Z","timestamp":1680560212000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0014488601976770"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,6]]},"references-count":23,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2001,6]]}},"alternative-id":["S0014488601976770"],"URL":"https:\/\/doi.org\/10.1006\/exnr.2001.7677","relation":{},"ISSN":["0014-4886"],"issn-type":[{"value":"0014-4886","type":"print"}],"subject":[],"published":{"date-parts":[[2001,6]]}}}