{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T05:47:19Z","timestamp":1790401639020,"version":"4.1.0"},"reference-count":50,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[1998,11,1]],"date-time":"1998-11-01T00:00:00Z","timestamp":909878400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Experimental Parasitology"],"published-print":{"date-parts":[[1998,11]]},"DOI":"10.1006\/expr.1998.4334","type":"journal-article","created":{"date-parts":[[2002,10,6]],"date-time":"2002-10-06T21:57:25Z","timestamp":1033941445000},"page":"203-211","source":"Crossref","is-referenced-by-count":20,"title":["Plasmodium vivax:A Monoclonal Antibody Recognizes a Circumsporozoite Protein Precursor on the Sporozoite Surface"],"prefix":"10.1006","volume":"90","author":[{"given":"Lilia","family":"Gonzalez-Ceron","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario H","family":"Rodriguez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert A","family":"Wirtz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara J","family":"Sina","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga L","family":"Palomeque","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose A","family":"Nettel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victor","family":"Tsutsumi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1006\/expr.1998.4334_PR984334RF1","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S0065-308X(08)60106-2","article-title":"Immunoelectron microscopy of parasites","volume":"29","author":"Aikawa","year":"1990","journal-title":"Advances in Parasitology"},{"key":"10.1006\/expr.1998.4334_PR984334RF2","doi-asserted-by":"crossref","DOI":"10.1016\/B978-0-12-045350-4.50008-1","article-title":"Ultrastructure of the major intracellular protozoa","author":"Aikawa","year":"1974"},{"key":"10.1006\/expr.1998.4334_PR984334RF3","doi-asserted-by":"crossref","first-page":"2494","DOI":"10.4049\/jimmunol.126.6.2494","article-title":"The protective Antigen of malarial sporozoites (Plasmodium berghei","volume":"126","author":"Aikawa","year":"1981","journal-title":"Journal of Immunology"},{"key":"10.1006\/expr.1998.4334_PR984334RF4","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1126\/science.2414847","article-title":"Circumsporozoite protein ofPlasmodium vivax","volume":"230","author":"Arnot","year":"1985","journal-title":"Science"},{"key":"10.1006\/expr.1998.4334_PR984334RF5","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/0166-6851(93)90182-W","article-title":"A conserved parasite serine protease processes thePlasmodium falciparum","volume":"62","author":"Blackman","year":"1993","journal-title":"Molecular and Biochemical Parasitology"},{"key":"10.1006\/expr.1998.4334_PR984334RF6","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1007\/BF00932418","article-title":"Developmental changes in the circumsporozoite proteins ofPlasmodium bergheiPlasmodium gallinaceum","volume":"81","author":"Boulanger","year":"1995","journal-title":"Parasitology Research"},{"key":"10.1006\/expr.1998.4334_PR984334RF7","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1016\/0092-8674(92)90251-7","article-title":"The basolateral domain of the hepatocyte plasma membrane bears receptors for the circumsporozoite protein ofPlasmodium falciparum","volume":"70","author":"Cerami","year":"1992","journal-title":"Cell"},{"key":"10.1006\/expr.1998.4334_PR984334RF8","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1093\/jmedent\/31.3.400","article-title":"Susceptibility of three laboratory strains ofAnopheles albimanusPlasmodium vivax","volume":"31","author":"Chan","year":"1994","journal-title":"Journal of Medical Netomology"},{"key":"10.1006\/expr.1998.4334_PR984334RF9","doi-asserted-by":"crossref","first-page":"5651","DOI":"10.1073\/pnas.79.18.5651","article-title":"Monoclonal antibodies identify the protective antigens of sporozoites ofPlasmodium knowlesi","volume":"79","author":"Cochrane","year":"1982","journal-title":"Proceedings of the National Academy of Sciences USA"},{"key":"10.1006\/expr.1998.4334_PR984334RF10","doi-asserted-by":"crossref","first-page":"501","DOI":"10.2307\/3273188","article-title":"A stain for malarial oocysts in temporary preparations","volume":"36","author":"Eyles","year":"1950","journal-title":"Journal of Parasitology"},{"key":"10.1006\/expr.1998.4334_PR984334RF11","doi-asserted-by":"crossref","first-page":"220","DOI":"10.4269\/ajtmh.1984.33.220","article-title":"Immuno-electron microscopy observations onPlasmodium knowlesi","volume":"33","author":"Fine","year":"1984","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"key":"10.1006\/expr.1998.4334_PR984334RF12","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1084\/jem.177.5.1287","article-title":"Malaria circumsporozoite protein binds to heparan sulfate proteoglycan associated with the surface membrane of hepatocytes","volume":"177","author":"Frevert","year":"1993","journal-title":"Journal of Experimental Medicine"},{"key":"10.1006\/expr.1998.4334_PR984334RF13","first-page":"35","article-title":"Factors influencing the development of protozoa in their arthropodan host","volume":"2","author":"Garnham","year":"1964"},{"key":"10.1006\/expr.1998.4334_PR984334RF14","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1177\/38.4.2181019","article-title":"The distribution of circumsporozoite protein (CS) inAnopheles stephensiPlasmodium falciparum","volume":"38","author":"Golenda","year":"1990","journal-title":"Journal of Histochemistry and Cytochemistry"},{"key":"10.1006\/expr.1998.4334_PR984334RF15","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1146\/annurev.iy.06.040188.003311","article-title":"The T cell response to the malaria circumsporozoite protein: An immunological approach to vaccine development","volume":"6","author":"Good","year":"1988","journal-title":"Annual Review of Inmunology"},{"key":"10.1006\/expr.1998.4334_PR984334RF16","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1017\/S0031182000058273","article-title":"Expression of circumsporozoite proteins revealed in situ in the mosquito stages ofPlasmodium berghei","volume":"96","author":"Hamilton","year":"1987","journal-title":"Parasitology"},{"key":"10.1006\/expr.1998.4334_PR984334RF17","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1084\/jem.178.5.1497","article-title":"Evidence for two-stage binding by the 175-kDa erythrocyte binding antigen ofPlasmodium falciparum","volume":"178","author":"Kain","year":"1993","journal-title":"Journal of Experimental Medicine"},{"key":"10.1006\/expr.1998.4334_PR984334RF18","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","article-title":"Cleavage of structural proteins during the assembly of the head of bacteriophage T4","volume":"227","author":"Lawmmli","year":"1970","journal-title":"Nature"},{"key":"10.1006\/expr.1998.4334_PR984334RF19","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/BF00931660","article-title":"Localization of circumsporozoite protein in the sporogonic stages ofPlasmodium vivax","volume":"78","author":"Meis","year":"1992","journal-title":"Parasitological Research"},{"key":"10.1006\/expr.1998.4334_PR984334RF20","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1038\/385336a0","article-title":"Circumsporozoite protein is required for development of malaria sporozoites in mosquitoes","volume":"385","author":"M\u00e9nard","year":"1997","journal-title":"Nature"},{"key":"10.1006\/expr.1998.4334_PR984334RF21","doi-asserted-by":"crossref","first-page":"2928","DOI":"10.1128\/IAI.55.12.2928-2932.1987","article-title":"Localization of circumsporozoite protein ofPlasmodium ovale","volume":"55","author":"Nagasawa","year":"1987","journal-title":"Infection and Immunity"},{"key":"10.1006\/expr.1998.4334_PR984334RF22","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/0014-4894(88)90047-1","article-title":"Plasmodium malarie","volume":"66","author":"Nagasawa","year":"1988","journal-title":"Experimental Parasitology"},{"key":"10.1006\/expr.1998.4334_PR984334RF23","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1084\/jem.156.1.20","article-title":"Circumsporozoite (CS) proteins of human malaria parasitesPlasmodium falcuparumPlasmodium vivax","volume":"156","author":"Nardin","year":"1982","journal-title":"Journal of Experimental Medicine"},{"key":"10.1006\/expr.1998.4334_PR984334RF24","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/0092-8674(85)90093-5","article-title":"Circumsporozoite proteins of malaria parasites","volume":"42","author":"Nussenzweig","year":"1985","journal-title":"Cell"},{"key":"10.1006\/expr.1998.4334_PR984334RF25","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1016\/0092-8674(83)90538-X","article-title":"Structure of thePlasmodium knowlesi","volume":"34","author":"Ozaki","year":"1983","journal-title":"Cell"},{"key":"10.1006\/expr.1998.4334_PR984334RF26","first-page":"18","article-title":"Immunogold localization of circumsporozoite protein of the malaria parasitePlasmodium falciparumAnopheles stephensi","volume":"46","author":"Posthuma","year":"1988","journal-title":"European Journal of Cell Biology"},{"key":"10.1006\/expr.1998.4334_PR984334RF27","doi-asserted-by":"crossref","first-page":"88","DOI":"10.2307\/3283350","article-title":"Effects of transmission-blocking immunity onPlasmodium vivaxAnopheles albimanus","volume":"80","author":"Ramsey","year":"1994","journal-title":"Journal of Parasitology"},{"key":"10.1006\/expr.1998.4334_PR984334RF28","doi-asserted-by":"crossref","first-page":"3883","DOI":"10.1002\/j.1460-2075.1995.tb00060.x","article-title":"Thrombospondin-related adhesive protein (TRAP) ofPlasmodium falciparum:","volume":"14","author":"Robson","year":"1995","journal-title":"EMBO Journal"},{"key":"10.1006\/expr.1998.4334_PR984334RF29","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1126\/science.2672336","article-title":"Circumsporozoite protein heterogeneity in the human malaria parasitePlasmodium vivax","volume":"245","author":"Rosenberg","year":"1989","journal-title":"Science"},{"key":"10.1006\/expr.1998.4334_PR984334RF30","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1016\/0169-4758(96)10030-2","article-title":"Rhoptry organelles of Apicomplexa: Their role in host cell invasion and intracellular survival","volume":"12","author":"Sam-Yellowe","year":"1996","journal-title":"Parasitology Today"},{"key":"10.1006\/expr.1998.4334_PR984334RF31","doi-asserted-by":"crossref","first-page":"3341","DOI":"10.1016\/S0021-9258(18)32866-7","article-title":"Structural similarities among the protective antigens of sporozoites from different species of malaria parasites","volume":"258","author":"Santoro","year":"1983","journal-title":"Journal of Biological Chemistry"},{"key":"10.1006\/expr.1998.4334_PR984334RF32","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/0166-6851(94)00198-V","article-title":"CSP-2: A protective antigen common toPlasmodium falciparumPlasmodium berghei","volume":"69","author":"Sina","year":"1995","journal-title":"Molecular and Biochemical Parasitology"},{"key":"10.1006\/expr.1998.4334_PR984334RF33","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/0035-9203(73)90031-X","article-title":"A comparative study on the ultrastructure ofPlasmodium","volume":"67","author":"Sinden","year":"1973","journal-title":"Transactions of the Royal Society of Tropical Medicine and Hygiene"},{"key":"10.1006\/expr.1998.4334_PR984334RF34","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/0035-9203(78)90167-0","article-title":"An ultrastructurel study of the sporogonic development ofPlasmodium falciparumAnopheles gambiae","volume":"72","author":"Sinden","year":"1978","journal-title":"Transactions of the Royal Society of Tropical Medicine and Hygiene"},{"key":"10.1006\/expr.1998.4334_PR984334RF35","doi-asserted-by":"crossref","first-page":"593","DOI":"10.2307\/3278847","article-title":"The passage ofPlasmodium bergheiAnopheles stephensi:","volume":"59","author":"Sterling","year":"1973","journal-title":"Journal of Parasitology"},{"key":"10.1006\/expr.1998.4334_PR984334RF36","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1111\/j.1550-7408.1985.tb03051.x","article-title":"Rhoptry secretion of membranous whorls byPlasmodium berghei","volume":"32","author":"Stewart","year":"1985","journal-title":"Journal of Protozoology"},{"key":"10.1006\/expr.1998.4334_PR984334RF37","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1111\/j.1550-7408.1991.tb01379.x","article-title":"Malaria sporozoites release circumsporozoite protein from their apical end and translocate it along their surface","volume":"38","author":"Stewart","year":"1991","journal-title":"Journal of Protozoology"},{"key":"10.1006\/expr.1998.4334_PR984334RF38","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1056\/NEJM199701093360202","article-title":"A preliminary evaluation of a recombinant circumsporozoite protein vaccine againstPlasmoidum falciparum","volume":"336","author":"Stoute","year":"1997","journal-title":"The New England Journal of Medicine"},{"key":"10.1006\/expr.1998.4334_PR984334RF39","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/S0092-8674(00)80511-5","article-title":"TRAP is necessary for gliding motility and infectivity ofPlasmodium","volume":"90","author":"Sultan","year":"1997","journal-title":"Cell"},{"key":"10.1006\/expr.1998.4334_PR984334RF40","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.4269\/ajtmh.1983.32.1203","article-title":"Anti-sporozoite antibodies induced by natural infection","volume":"32","author":"Tapchaisri","year":"1983","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"key":"10.1006\/expr.1998.4334_PR984334RF41","doi-asserted-by":"crossref","first-page":"1607","DOI":"10.1084\/jem.175.6.1607","article-title":"Developmentally regulated infectivity of malaria sporozoites for mosquito salivary glands and the vertebrate host","volume":"175","author":"Touray","year":"1992","journal-title":"Journal of Experimental Medicine"},{"key":"10.1006\/expr.1998.4334_PR984334RF42","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/0035-9203(81)90061-4","article-title":"Preliminary observations on the cell surface ofPlasmodium gallinaceum","volume":"757","author":"Turner","year":"1981","journal-title":"Transactions of the Royal Society of Tropical Medicine and Hygiene"},{"key":"10.1006\/expr.1998.4334_PR984334RF43","doi-asserted-by":"crossref","first-page":"43","DOI":"10.2307\/3279102","article-title":"Development of infectivity byPlasmodium berghei","volume":"61","author":"Vanderberg","year":"1975","journal-title":"Journal of Parasitology"},{"key":"10.1006\/expr.1998.4334_PR984334RF44","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0014-4894(82)90061-3","article-title":"Plasmodium berghei:","volume":"53","author":"Vermeulen","year":"1982","journal-title":"Experimental Parasitology"},{"key":"10.1006\/expr.1998.4334_PR984334RF45","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/0014-4894(92)90215-V","article-title":"Plasmodium gallinaceum:Aedes aegypti","volume":"75","author":"Warburg","year":"1992","journal-title":"Experimental Parasitology"},{"key":"10.1006\/expr.1998.4334_PR984334RF46","first-page":"30","year":"1967","journal-title":"Technical Report Series No. 375"},{"key":"10.1006\/expr.1998.4334_PR984334RF47","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.4269\/ajtmh.1985.34.1048","article-title":"Identification ofPlasmodium vivax","volume":"34","author":"Wirtz","year":"1985","journal-title":"American Journal of Tropical Medicine and Hygiene"},{"key":"10.1006\/expr.1998.4334_PR984334RF48","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/0140-6736(90)93393-4","article-title":"Prevalence of antibody to heterologous circumsporozoite protein ofPlasmodium vivax","volume":"336","author":"Wirtz","year":"1990","journal-title":"Lancet"},{"key":"10.1006\/expr.1998.4334_PR984334RF49","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1093\/jmedent\/29.5.854","article-title":"Development and evaluation of an enzyme linked immunosorbent assay forPlasmodium vivax","volume":"29","author":"Wirtz","year":"1992","journal-title":"Journal of Medical Entomology"},{"key":"10.1006\/expr.1998.4334_PR984334RF50","doi-asserted-by":"crossref","first-page":"1225","DOI":"10.1084\/jem.154.4.1225","article-title":"Biosynthesis of Pb 44, the protective antigen of sporozites ofPlasmodium berghei","volume":"154","author":"Yoshida","year":"1981","journal-title":"Journal of Experimental Medicine"}],"container-title":["Experimental Parasitology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001448949894334X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S001448949894334X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,4,4]],"date-time":"2023-04-04T15:02:06Z","timestamp":1680620526000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S001448949894334X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,11]]},"references-count":50,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1998,11]]}},"alternative-id":["S001448949894334X"],"URL":"https:\/\/doi.org\/10.1006\/expr.1998.4334","relation":{},"ISSN":["0014-4894"],"issn-type":[{"value":"0014-4894","type":"print"}],"subject":[],"published":{"date-parts":[[1998,11]]}}}