{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T11:23:45Z","timestamp":1783596225198,"version":"3.55.0"},"reference-count":36,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2001,6,1]],"date-time":"2001-06-01T00:00:00Z","timestamp":991353600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Genomics"],"published-print":{"date-parts":[[2001,6]]},"DOI":"10.1006\/geno.2001.6542","type":"journal-article","created":{"date-parts":[[2002,9,17]],"date-time":"2002-09-17T18:31:03Z","timestamp":1032287463000},"page":"180-185","source":"Crossref","is-referenced-by-count":56,"title":["A New Locus for Hereditary Gingival Fibromatosis (GINGF2) Maps to 5q13\u2013q22"],"prefix":"10.1006","volume":"74","author":[{"given":"Shangxi","family":"Xiao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Bu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liqin","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangyong","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minghua","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meiqian","family":"Qian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Landian","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoping","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangyin","family":"Kong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1006\/geno.2001.6542_RF1","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1111\/j.1600-0714.1991.tb00438.x","article-title":"Hereditary gingival fibromatosis in a family with the Zimmermann\u2013Laband syndrome","volume":"20","author":"Bakaeen","year":"1991","journal-title":"J. Oral Pathol. Med."},{"key":"10.1006\/geno.2001.6542_RF2","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/0003-9969(94)00187-G","article-title":"Changes in extracellular matrix macromolecules in human gingiva after treatment with drugs inducing gingival overgrowth","volume":"40","author":"Bonnaure-Mallet","year":"1995","journal-title":"Arch. Oral Biol."},{"key":"10.1006\/geno.2001.6542_RF3","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/0030-4220(94)90037-X","article-title":"Hereditary gingival fibromatosis. Report of an extensive four-generation pedigree","volume":"78","author":"Bozzo","year":"1994","journal-title":"Oral Surg. Oral Med. Oral Pathol."},{"key":"10.1006\/geno.2001.6542_RF4","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1111\/j.1600-0765.1998.tb02346.x","article-title":"Differential proliferation of fibroblasts cultured from hereditary gingival fibromatosis and normal gingiva","volume":"33","author":"Coletta","year":"1998","journal-title":"J. Periodontal Res."},{"key":"10.1006\/geno.2001.6542_RF5","doi-asserted-by":"crossref","first-page":"237","DOI":"10.3109\/03008209909000702","article-title":"Increase in expression of Hsp47 and collagen in hereditary gingival fibromatosis is modulated by stress and terminal procollagen N-propeptides","volume":"40","author":"Coletta","year":"1999","journal-title":"Connect. Tissue Res."},{"key":"10.1006\/geno.2001.6542_RF6","first-page":"252","article-title":"Faster sequential genetic linkage computations","volume":"53","author":"Cottingham","year":"1993","journal-title":"Am. J. Hum. Genet."},{"key":"10.1006\/geno.2001.6542_RF7","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/0278-2391(88)90229-7","article-title":"Hereditary generalized gingival fibromatosis associated with hypertrichosis: Report of five cases in one family","volume":"46","author":"Cuestas-Carnero","year":"1988","journal-title":"J. Oral. Maxillofacial Surg."},{"key":"10.1006\/geno.2001.6542_RF8","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1038\/ng1193-242","article-title":"Nonsense mutations in the C-terminal SH2 region of the GTPase activating protein (GAP) gene in human tumours","volume":"5","author":"Friedman","year":"1993","journal-title":"Nat. Genet."},{"key":"10.1006\/geno.2001.6542_RF9","first-page":"54","article-title":"Gingival fibromatosis and partial duplication of the short arm of chromosome 2 (dup(2)(p13 \u2192 p21))","volume":"39","author":"Fryns","year":"1996","journal-title":"Ann. Genet."},{"key":"10.1006\/geno.2001.6542_RF10","doi-asserted-by":"crossref","first-page":"876","DOI":"10.1086\/301797","article-title":"Genetic linkage of hereditary gingival fibromatosis to chromosome 2p21","volume":"62","author":"Hart","year":"1998","journal-title":"Am. J. Hum. Genet."},{"key":"10.1006\/geno.2001.6542_RF11","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1002\/ajmg.1320220323","article-title":"Gingival fibromatosis with sensorineural hearing loss: An autosomal dominant trait","volume":"22","author":"Hartsfield","year":"1985","journal-title":"Am. J. Med. Genet."},{"key":"10.1006\/geno.2001.6542_RF12","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1177\/10454411910020010201","article-title":"Drug-induced gingival overgrowth: Old problem, new problem","volume":"2","author":"Hassell","year":"1991","journal-title":"Crit. Rev. Oral Biol. Med."},{"key":"10.1006\/geno.2001.6542_RF13","first-page":"195","article-title":"Familial gingival fibromatosis associated with progressive deafness in five generations of a family","volume":"13","author":"Jones","year":"1977","journal-title":"Birth Defects Orig. Artic. Ser."},{"key":"10.1006\/geno.2001.6542_RF14","doi-asserted-by":"crossref","first-page":"9061","DOI":"10.1074\/jbc.274.13.9061","article-title":"Differential effects of a calcineurin inhibitor on glutamate-induced phosphorylation of Ca2+\/calmodulin-dependent protein kinases in cultured rat hippocampal neurons","volume":"274","author":"Kasahara","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1006\/geno.2001.6542_RF15","first-page":"161","article-title":"Gingival fibromatosis: Study of three generations with consanguinity","volume":"24","author":"Kharbanda","year":"1993","journal-title":"Quintessence Int."},{"key":"10.1006\/geno.2001.6542_RF16","doi-asserted-by":"crossref","first-page":"3443","DOI":"10.1073\/pnas.81.11.3443","article-title":"Strategies for multilocus linkage analysis in humans","volume":"81","author":"Lathrop","year":"1984","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1006\/geno.2001.6542_RF17","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1038\/364208a0","article-title":"Molecular basis of the little mouse phenotype and implications for cell type-specific growth","volume":"364","author":"Lin","year":"1993","journal-title":"Nature"},{"key":"10.1006\/geno.2001.6542_RF18","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1002\/ajmg.1320350118","article-title":"Ectro-amelia syndrome associated with an interstitial deletion of 7q","volume":"35","author":"Morey","year":"1990","journal-title":"Am. J. Med. Genet."},{"key":"10.1006\/geno.2001.6542_RF19","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1093\/hmg\/9.1.87","article-title":"Significant evidence for linkage of febrile seizures to chromosome 5q14\u2013q15","volume":"9","author":"Nakayama","year":"2000","journal-title":"Hum. Mol. Genet."},{"key":"10.1006\/geno.2001.6542_RF20","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/0266-4356(90)90111-W","article-title":"Hereditary gingival fibromatosis associated with growth hormone deficiency","volume":"28","author":"Oikarinen","year":"1990","journal-title":"Br. J. Oral Maxillofac. Surg."},{"key":"10.1006\/geno.2001.6542_RF21","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1002\/ajmg.1320250305","article-title":"Cherubism, gingival fibromatosis, epilepsy, and mental deficiency (Ramon syndrome) with juvenile rheumatoid arthritis","volume":"25","author":"Pina-Neto","year":"1986","journal-title":"Am. J. Med. Genet."},{"key":"10.1006\/geno.2001.6542_RF22","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1016\/S0888-7543(05)80262-9","article-title":"Physical localization of chromosome 20 markers using somatic cell hybrid cell lines and fluorescence in situ hybridization","volume":"14","author":"Rao","year":"1992","journal-title":"Genomics"},{"key":"10.1006\/geno.2001.6542_RF23","first-page":"97","article-title":"Opposite imbalances of distal 14q in two unrelated patients","volume":"35","author":"Rivera","year":"1992","journal-title":"Ann. Genet."},{"key":"10.1006\/geno.2001.6542_RF24","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1159\/000154222","article-title":"Avoiding recomputation in linkage analysis","volume":"44","author":"Schaffer","year":"1994","journal-title":"Hum. Hered."},{"key":"10.1006\/geno.2001.6542_RF25","first-page":"683","article-title":"Genetic heterogeneity of gingival fibromatosis on chromosome 2p","volume":"36","author":"Shashi","year":"1999","journal-title":"J. Med. Genet."},{"key":"10.1006\/geno.2001.6542_RF26","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1111\/j.1600-0714.1988.tb01301.x","article-title":"Abnormal cellular property of fibroblasts from congenital gingival fibromatosis","volume":"17","author":"Shirasuna","year":"1988","journal-title":"J. Oral Pathol."},{"key":"10.1006\/geno.2001.6542_RF27","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1111\/j.1834-7819.1993.tb04755.x","article-title":"Hereditary gingival fibromatosis with a recessive mode of inheritance. Case reports","volume":"38","author":"Singer","year":"1993","journal-title":"Aust. Dent. J."},{"key":"10.1006\/geno.2001.6542_RF28","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1111\/j.1600-0765.1989.tb00874.x","article-title":"Hereditary gingival fibromatosis: Report on three families and dermatoglyphic analysis","volume":"24","author":"Skrinjaric","year":"1989","journal-title":"J. Periodontal Res."},{"key":"10.1006\/geno.2001.6542_RF29","first-page":"1323","article-title":"Descent graphs in pedigree analysis: applications to haplotyping, location scores, and marker-sharing statistics","volume":"58","author":"Sobel","year":"1996","journal-title":"Am. J. Hum. Genet."},{"key":"10.1006\/geno.2001.6542_RF30","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1002\/ajmg.1320470415","article-title":"Natural history of the recombinant (8) syndrome","volume":"47","author":"Sujansky","year":"1993","journal-title":"Am. J. Med. Genet."},{"key":"10.1006\/geno.2001.6542_RF31","doi-asserted-by":"crossref","first-page":"2202","DOI":"10.1002\/1097-0142(19911115)68:10<2202::AID-CNCR2820681019>3.0.CO;2-O","article-title":"Heterogeneity in the gingival fibromatoses","volume":"68","author":"Takagi","year":"1991","journal-title":"Cancer"},{"key":"10.1006\/geno.2001.6542_RF32","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1902\/jop.1997.68.6.524","article-title":"Increased proliferation, collagen, and fibronectin production by hereditary gingival fibromatosis fibroblasts","volume":"68","author":"Tipton","year":"1997","journal-title":"J. Periodontol."},{"key":"10.1006\/geno.2001.6542_RF33","first-page":"321","article-title":"Zimmermann\u2013Laband syndrome in a patient with severe mental retardation","volume":"6","author":"Van Buggenhout","year":"1995","journal-title":"Genet. Couns."},{"key":"10.1006\/geno.2001.6542_RF34","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1902\/jop.1995.66.1.75","article-title":"Hereditary gingival fibromatosis associated with hearing loss and supernumerary teeth\u2014A new syndrome","volume":"66","author":"Wynne","year":"1995","journal-title":"J. Periodontol."},{"key":"10.1006\/geno.2001.6542_RF35","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1006\/geno.2000.6285","article-title":"Refinement of the locus for autosomal dominant hereditary gingival fibromatosis to a 3.8 cM region on 2p21","volume":"68","author":"Xiao","year":"2000","journal-title":"Genomics"},{"key":"10.1006\/geno.2001.6542_RF36","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1136\/jmg.26.2.130","article-title":"A terminal deletion (14)(q31.1) in a child with microcephaly, narrow palate, gingival hypertrophy, protuberant ears, and mild mental retardation","volume":"26","author":"Yen","year":"1989","journal-title":"J. Med. Genet."}],"container-title":["Genomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0888754301965425?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0888754301965425?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,8]],"date-time":"2019-05-08T06:32:00Z","timestamp":1557297120000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0888754301965425"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,6]]},"references-count":36,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2001,6]]}},"alternative-id":["S0888754301965425"],"URL":"https:\/\/doi.org\/10.1006\/geno.2001.6542","relation":{},"ISSN":["0888-7543"],"issn-type":[{"value":"0888-7543","type":"print"}],"subject":[],"published":{"date-parts":[[2001,6]]}}}