{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T08:37:27Z","timestamp":1762504647709},"reference-count":31,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[1997,3,1]],"date-time":"1997-03-01T00:00:00Z","timestamp":857174400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gynecologic Oncology"],"published-print":{"date-parts":[[1997,3]]},"DOI":"10.1006\/gyno.1996.4582","type":"journal-article","created":{"date-parts":[[2002,10,6]],"date-time":"2002-10-06T21:38:48Z","timestamp":1033940328000},"page":"496-500","source":"Crossref","is-referenced-by-count":37,"title":["Angiogenesis in Vulvar Intraepithelial Neoplasia"],"prefix":"10.1006","volume":"64","author":[{"given":"Dagmar","family":"Bancher-Todesca","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Obermair","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Selcuk","family":"Bilgi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petra","family":"Kohlberger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Kainz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerhard","family":"Breitenecker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sepp","family":"Leodolter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerald","family":"Gitsch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1006\/gyno.1996.4582_GO964582C1","series-title":"The Molecular Basis of Cancer","article-title":"Tumor Angiogenesis","author":"Folkman","year":"1995"},{"key":"10.1006\/gyno.1996.4582_GO964582C2","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1056\/NEJM197111182852108","article-title":"Tumor angiogenesis: Therapeutic implications","volume":"285","author":"Folkman","year":"1971","journal-title":"N Engl J Med"},{"key":"10.1006\/gyno.1996.4582_GO964582C3","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1084\/jem.136.2.261","article-title":"Tumor dormancy in vivo by prevention of neovascularization","volume":"136","author":"Gimbrone","year":"1972","journal-title":"J Exp Med"},{"key":"10.1006\/gyno.1996.4582_GO964582C4","doi-asserted-by":"crossref","first-page":"5822","DOI":"10.1038\/362841a0","article-title":"Inhibition of vascular endothelial growth factor-induced angiogenesis supresses tumor growth in vivo","volume":"362","author":"Kim","year":"1993","journal-title":"Nature"},{"key":"10.1006\/gyno.1996.4582_GO964582C5","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1038\/367576a0","article-title":"Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant","volume":"364","author":"Millauer","year":"1994","journal-title":"Nature"},{"key":"10.1006\/gyno.1996.4582_GO964582C6","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1038\/bjc.1995.323","article-title":"Tumor vasculature\u2014A potential therapeutic target","volume":"72","author":"Baillie","year":"1995","journal-title":"Br J Cancer"},{"key":"10.1006\/gyno.1996.4582_GO964582C7","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1126\/science.2479986","article-title":"Vascular endothelial growth factor is a secreted angiogenic mitogen","volume":"246","author":"Leung","year":"1989","journal-title":"Science"},{"key":"10.1006\/gyno.1996.4582_GO964582C8","first-page":"1774","article-title":"Purification and NH2","volume":"50","author":"Senger","year":"1990","journal-title":"Cancer Res"},{"key":"10.1006\/gyno.1996.4582_GO964582C9","first-page":"213","article-title":"Tumor-secreted vascular permeability factor increases cytosolic Ca2+","volume":"138","author":"Brock","year":"1991","journal-title":"Am J Pathol"},{"key":"10.1006\/gyno.1996.4582_GO964582C10","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1111\/j.1749-6632.1995.tb17435.x","article-title":"The regulation of blood vessel growth by vascular endothelial growth factor","volume":"752","author":"Ferrara","year":"1995","journal-title":"Ann NY Acad Sci"},{"key":"10.1006\/gyno.1996.4582_GO964582C11","first-page":"1029","article-title":"Vascular permeability factor\/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis","volume":"146","author":"Dvorak","year":"1995","journal-title":"Am J Pathol"},{"key":"10.1006\/gyno.1996.4582_GO964582C12","first-page":"741","article-title":"Vulvar intraepithelial neoplasia III: A clinical study of the outcome in 113 cases with relation to the later development of invasive vulvar carcinoma","volume":"84","author":"Jones","year":"1994","journal-title":"Obstet Gynecol"},{"key":"10.1006\/gyno.1996.4582_GO964582C13","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1006\/gyno.1994.1039","article-title":"Vulvar squamous cell carcinoma and papillomaviruses: Indications for two different etiologies","volume":"52","author":"Hording","year":"1994","journal-title":"Gynecol Oncol"},{"key":"10.1006\/gyno.1996.4582_GO964582C14","series-title":"Atlas of Tumor Pathology: Tumors of the Cervix, Vagina, and Vulva","first-page":"179","article-title":"Tumors of the Vulva","author":"Kurman","year":"1992"},{"key":"10.1006\/gyno.1996.4582_GO964582C15","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1002\/ijc.2910620203","article-title":"Microvessel density and vessel invasion in lymph-node negative breast cancer: Effect on recurrence-free survival","volume":"62","author":"Obermair","year":"1995","journal-title":"Int J Cancer"},{"key":"10.1006\/gyno.1996.4582_GO964582C16","series-title":"Rank Correlation Methods","author":"Kendall","year":"1970"},{"key":"10.1006\/gyno.1996.4582_GO964582C17","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1111\/j.1365-2559.1994.tb00010.x","article-title":"Basement membrane and extracellular interstitial matrix components in bladder neoplasia\u2014Evidence of angiogenesis","volume":"25","author":"Deen","year":"1994","journal-title":"Histopathology"},{"key":"10.1006\/gyno.1996.4582_GO964582C18","doi-asserted-by":"crossref","first-page":"880","DOI":"10.1126\/science.402692","article-title":"Angiogenesis: A marker for neoplastic transformation of mammary papillary hyperplasia","volume":"195","author":"Brem","year":"1977","journal-title":"Science"},{"key":"10.1006\/gyno.1996.4582_GO964582C19","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1002\/1097-0142(197801)41:1<239::AID-CNCR2820410133>3.0.CO;2-X","article-title":"Angiogenesis as a marker of preneoplastic lesions of the human breast","volume":"41","author":"Brem","year":"1978","journal-title":"Cancer"},{"key":"10.1006\/gyno.1996.4582_GO964582C20","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1038\/339058a0","article-title":"Induction of angiogenesis during the transition from hyperplasia to neoplasia","volume":"339","author":"Folkman","year":"1989","journal-title":"Nature"},{"key":"10.1006\/gyno.1996.4582_GO964582C21","first-page":"800","article-title":"Demonstration and characterization of the angiogenic properties of cervical dysplasia","volume":"54","author":"Smith-McKune","year":"1994","journal-title":"Cancer Res"},{"key":"10.1006\/gyno.1996.4582_GO964582C22","series-title":"Advances in Immunohistochemistry","first-page":"363","article-title":"Basement Membrane and Endothelial Agents: Their Role in Evaluation of Tumor Invasion and Metastasis","author":"Lee","year":"1988"},{"key":"10.1006\/gyno.1996.4582_GO964582C23","first-page":"9","article-title":"Intratumoral microvessel density as a prognostic factor in cancer","volume":"147","author":"Weidner","year":"1995","journal-title":"Am J Pathol"},{"key":"10.1006\/gyno.1996.4582_GO964582C24","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1093\/jnci\/87.3.213","article-title":"Enhancement of tumor growth and vascular density by transfection of vascular endothelial cell growth factor into MCF-7 human breast carcinoma cells","volume":"87","author":"Zhang","year":"1995","journal-title":"J Natl Cancer Inst"},{"key":"10.1006\/gyno.1996.4582_GO964582C25","doi-asserted-by":"crossref","first-page":"1045","DOI":"10.1111\/j.1349-7006.1994.tb02904.x","article-title":"Association of vascular endothelial growth factor expression with tumor angiogenesis and with early relapse in primary breast cancer","volume":"85","author":"Toi","year":"1994","journal-title":"Jpn J Cancer Res"},{"key":"10.1006\/gyno.1996.4582_GO964582C26","first-page":"3964","article-title":"Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity metastasis, and proliferation of human colon cancer","volume":"55","author":"Takahashi","year":"1995","journal-title":"Cancer Res"},{"key":"10.1006\/gyno.1996.4582_GO964582C27","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1084\/jem.174.5.1275","article-title":"Distribution of vascular permeability factor (vascular endothelial growth factor) in tumors: Concentration in tumor blood vessels","volume":"174","author":"Dvorak","year":"1991","journal-title":"J Exp Med"},{"key":"10.1006\/gyno.1996.4582_GO964582C28","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1177\/43.4.7534783","article-title":"Ultrastructural localization of vascular permeability factor\/vascular endothelial growth factor (VPF\/VEGF) to the abluminal plasma membrane and vesiculovacuolar organelles of tumor microvascular endothelium","volume":"43","author":"Qu-Hong Nagy","year":"1995","journal-title":"J Histochem Cytochem"},{"key":"10.1006\/gyno.1996.4582_GO964582C29","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1097\/00007435-199205000-00009","article-title":"Prognostic factors in cervical human papillomavirus infections","volume":"19","author":"Kataja","year":"1992","journal-title":"Sex Transm Dis"},{"key":"10.1006\/gyno.1996.4582_GO964582C30","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1007\/BF02456675","article-title":"Behaviour of cervical intraepithelial neoplasia (CIN) associated with various human papillomavirus (HPV) types","volume":"252","author":"Hellberg","year":"1993","journal-title":"Arch Gynecol Obstet"},{"key":"10.1006\/gyno.1996.4582_GO964582C31","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1093\/jnci\/86.7.539","article-title":"Enhancement of regression of cervical intraepithelial neoplasia II (moderate dysplasia) with topically applied all-trans","volume":"86","author":"Meyskens","year":"1994","journal-title":"J Natl Cancer Inst"}],"container-title":["Gynecologic Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090825896945825?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090825896945825?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,8]],"date-time":"2019-05-08T01:52:44Z","timestamp":1557280364000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0090825896945825"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1997,3]]},"references-count":31,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1997,3]]}},"alternative-id":["S0090825896945825"],"URL":"https:\/\/doi.org\/10.1006\/gyno.1996.4582","relation":{},"ISSN":["0090-8258"],"issn-type":[{"value":"0090-8258","type":"print"}],"subject":[],"published":{"date-parts":[[1997,3]]}}}