{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T10:07:46Z","timestamp":1760782066731},"reference-count":23,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2001,11,1]],"date-time":"2001-11-01T00:00:00Z","timestamp":1004572800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gynecologic Oncology"],"published-print":{"date-parts":[[2001,11]]},"DOI":"10.1006\/gyno.2001.6431","type":"journal-article","created":{"date-parts":[[2002,9,17]],"date-time":"2002-09-17T22:50:18Z","timestamp":1032303018000},"page":"383-387","source":"Crossref","is-referenced-by-count":7,"title":["Germline BRCA1\u20132 Mutations in Non-Ashkenazi Families with Double Primary Breast and Ovarian Cancer"],"prefix":"10.1006","volume":"83","author":[{"given":"John O.","family":"Schorge","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neda M.","family":"Mahoney","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David S.","family":"Miller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert L.","family":"Coleman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolyn Y.","family":"Muller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David M.","family":"Euhus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gail E.","family":"Tomlinson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1006\/gyno.2001.6431_RF1","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1006\/gyno.2000.5895","article-title":"Patients with double primary tumors in the breast and ovary\u2014clinical characteristics and BRCA1\u20132 mutations status","volume":"79","author":"Fishman","year":"2000","journal-title":"Gynecol Oncol"},{"key":"10.1006\/gyno.2001.6431_RF2","first-page":"505","article-title":"The founder mutations 185delAG and 5382insC in BRCA1 and 6174delT in BRCA2 appear in 60% of ovarian cancer and 30% of early-onset breast cancer patients among Ashkenazi women","volume":"60","author":"Abeliovich","year":"1997","journal-title":"Am J Hum Genet"},{"key":"10.1006\/gyno.2001.6431_RF3","doi-asserted-by":"crossref","first-page":"1823","DOI":"10.1001\/jama.1996.03540220047029","article-title":"High frequency of BRCA1 185delAG mutation in ovarian cancer in Israel","volume":"276","author":"Modan","year":"1996","journal-title":"J Am Med Assoc"},{"key":"10.1006\/gyno.2001.6431_RF4","first-page":"1059","article-title":"Founder BRCA1 and BRCA2 mutations in Ashkenazi Jews in Israel: frequency and differential penetrance in ovarian cancer and in breast-ovarian cancer families","volume":"60","author":"Levy-Lahad","year":"1997","journal-title":"Am J Hum Genet"},{"key":"10.1006\/gyno.2001.6431_RF5","doi-asserted-by":"crossref","first-page":"2417","DOI":"10.1200\/JCO.1998.16.7.2417","article-title":"Sequence analysis of BRCA1 and BRCA2: correlation of mutations with family history and ovarian cancer risk","volume":"16","author":"Frank","year":"1998","journal-title":"J Clin Oncol"},{"key":"10.1006\/gyno.2001.6431_RF6","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1097\/00000658-200005000-00002","article-title":"Testing for hereditary breast and ovarian cancer in the southeastern United States","volume":"231","author":"Miron","year":"2000","journal-title":"Ann Surg"},{"key":"10.1006\/gyno.2001.6431_RF7","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1086\/301880","article-title":"Evidence of founder mutations in Finnish BRCA1 and BRCA2 families","volume":"62","author":"Huusko","year":"1998","journal-title":"Am J Hum Genet"},{"key":"10.1006\/gyno.2001.6431_RF8","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1086\/302099","article-title":"Founder BRCA1 and BRCA2 mutations in French Canadian breast and ovarian cancer families","volume":"63","author":"Tonin","year":"1998","journal-title":"Am J Hum Genet"},{"key":"10.1006\/gyno.2001.6431_RF9","first-page":"392","article-title":"Common origins of BRCA1 mutations in Canadian breast and ovarian cancer families","volume":"8","author":"Simard","year":"1994","journal-title":"Nature"},{"key":"10.1006\/gyno.2001.6431_RF10","first-page":"1041","article-title":"A high proportion of novel mutations in BRCA1 with strong founder effects among Dutch and Belgian hereditary breast and ovarian cancer families","volume":"60","author":"Peelen","year":"1997","journal-title":"Am J Hum Genet"},{"key":"10.1006\/gyno.2001.6431_RF11","first-page":"441","article-title":"Founding BRCA1 mutations in hereditary breast and ovarian cancer in southern Sweden","volume":"58","author":"Johannsson","year":"1996","journal-title":"Am J Hum Genet"},{"key":"10.1006\/gyno.2001.6431_RF12","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1086\/302511","article-title":"Evidence for a BRCA1 founder mutation in families of West African ancestry [letter]","volume":"65","author":"Mefford","year":"1999","journal-title":"Am J Hum Genet"},{"key":"10.1006\/gyno.2001.6431_RF13","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1093\/hmg\/8.5.889","article-title":"Germline BRCA1 alterations in a population-based series of ovarian cancer cases","volume":"8","author":"Janezic","year":"1999","journal-title":"Hum Mol Genet"},{"key":"10.1006\/gyno.2001.6431_RF14","first-page":"4259","article-title":"BRCA1 and BRCA2 mutations in breast cancer families with multiple primary cancers","volume":"6","author":"Shih","year":"2000","journal-title":"Clin Cancer Res"},{"key":"10.1006\/gyno.2001.6431_RF15","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1093\/jnci\/89.3.227","article-title":"Probability of carrying a mutation of breast\u2013ovarian cancer gene BRCA1 based on family history","volume":"89","author":"Berry","year":"1997","journal-title":"J Natl Cancer Inst"},{"key":"10.1006\/gyno.2001.6431_RF16","unstructured":"Myriad Genetic Laboratories. BRACAnalysis\u2122 Technical Specifications. April 2000."},{"key":"10.1006\/gyno.2001.6431_RF17","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1002\/humu.1380020402","article-title":"A suggested nomenclature for designating mutations","volume":"2","author":"Beaudet","year":"1993","journal-title":"Hum Mut"},{"key":"10.1006\/gyno.2001.6431_RF18","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1038\/ng1294-399","article-title":"Confirmation of BRCA1 by analysis of germline mutations linked to breast and ovarian cancer in ten families","volume":"8","author":"Friedman","year":"1994","journal-title":"Nat Genet"},{"key":"10.1006\/gyno.2001.6431_RF19","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1038\/ng1196-253","article-title":"A polymorphic stop codon in BRCA2","volume":"14","author":"Mazoyer","year":"1996","journal-title":"Nat Genet"},{"key":"10.1006\/gyno.2001.6431_RF20","unstructured":"Breast Cancer Information Core. http:\/\/www.nhgri.nih.gov\/Intramural_research\/Lab_transfer\/BIC, 1997."},{"key":"10.1006\/gyno.2001.6431_RF21","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1038\/ng0197-103","article-title":"Variation of risks of breast and ovarian cancer associated with different germline mutations of the BRCA2 gene","volume":"15","author":"Gayther","year":"1997","journal-title":"Nat Genet"},{"key":"10.1006\/gyno.2001.6431_RF22","first-page":"59","article-title":"Ovarian cancer risk reduction after bilateral prophylactic oophorectomy (BPO) in BRCA1 and BRCA2 mutation carriers (abstract)","volume":"67","author":"Weber","year":"2000","journal-title":"Am J Hum Genet"},{"key":"10.1006\/gyno.2001.6431_RF23","first-page":"58","article-title":"Reduction in breast cancer risk following bilateral prophylactic oophorectomy in BRCA1 and BRCA2 mutation carriers (abstract)","volume":"67","author":"Eisen","year":"2000","journal-title":"Am J Hum Genet"}],"container-title":["Gynecologic Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090825801964315?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090825801964315?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,8]],"date-time":"2019-05-08T18:23:30Z","timestamp":1557339810000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0090825801964315"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,11]]},"references-count":23,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2001,11]]}},"alternative-id":["S0090825801964315"],"URL":"https:\/\/doi.org\/10.1006\/gyno.2001.6431","relation":{},"ISSN":["0090-8258"],"issn-type":[{"value":"0090-8258","type":"print"}],"subject":[],"published":{"date-parts":[[2001,11]]}}}