{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T16:16:12Z","timestamp":1762100172744},"reference-count":62,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2004,4,1]],"date-time":"2004-04-01T00:00:00Z","timestamp":1080777600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Oral and Maxillofacial Surgery"],"published-print":{"date-parts":[[2004,4]]},"DOI":"10.1006\/ijom.2002.0472","type":"journal-article","created":{"date-parts":[[2004,4,14]],"date-time":"2004-04-14T05:25:54Z","timestamp":1081920354000},"page":"286-293","source":"Crossref","is-referenced-by-count":41,"title":["The effect of alendronate on resorption of the alveolar bone following tooth extraction"],"prefix":"10.1006","volume":"33","author":[{"given":"H.","family":"Altundal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00d6.","family":"G\u00fcvener","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1006\/ijom.2002.0472_RF1","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1136\/adc.86.5.356","article-title":"Beneficial effect of long-term intravenous bisphosphonate treatment of osteogenesis imperfecta","volume":"86","author":"Astrom","year":"2002","journal-title":"Arch Dis Child"},{"key":"10.1006\/ijom.2002.0472_RF2","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/0022-3913(71)90069-2","article-title":"Reduction of residual ridge: a major oral disease entity","volume":"26","author":"Atwood","year":"1971","journal-title":"J Prosthet Dent"},{"key":"10.1006\/ijom.2002.0472_RF3","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1016\/0022-3913(63)90225-7","article-title":"Postextraction changes in the adult mandible as illustrated by microradiographs of midsagittal sections and serial cephalometric roentgenograms","volume":"13","author":"Atwood","year":"1963","journal-title":"J Prosthet Dent"},{"key":"10.1006\/ijom.2002.0472_RF4","first-page":"277","article-title":"Long-term safety of the aminobisphosphonate alendronate in adult dogs. II. Histomorphometric analysis of the L5 vertebrae","volume":"276","author":"Balena","year":"1996","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1006\/ijom.2002.0472_RF5","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1902\/jop.1998.69.8.920","article-title":"A prospective clinical trial of endosseous screw-shaped implants placed at the time of tooth extraction without augmentation","volume":"69","author":"Becker","year":"1998","journal-title":"J Periodontol"},{"key":"10.1006\/ijom.2002.0472_RF6","doi-asserted-by":"crossref","first-page":"3034","DOI":"10.1210\/jc.82.9.3034","article-title":"Short-term variations in bone remodeling biochemical markers: cyclical etidronate and alendronate effects compared","volume":"82","author":"Bettica","year":"1997","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1006\/ijom.2002.0472_RF7","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1902\/jop.2000.71.8.1236","article-title":"Effectiveness of local delivery of alendronate in reducing alveolar bone loss following periodontal surgery in rats","volume":"71","author":"Binderman","year":"2000","journal-title":"J Periodontol"},{"key":"10.1006\/ijom.2002.0472_RF8","first-page":"538","article-title":"Effects of bisphosphonates on matrix mineralization","volume":"2","author":"Boivin","year":"2002","journal-title":"J Musculoskel Neuron Interact"},{"key":"10.1006\/ijom.2002.0472_RF9","first-page":"40","article-title":"The mechanism of inhibition of farnesyl diphosnate synthase by nitrogen-containing bisphosphonates","volume":"30","author":"Dunford","year":"2002","journal-title":"Bone"},{"key":"10.1006\/ijom.2002.0472_RF10","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1016\/S8756-3282(02)00869-4","article-title":"Effects of long-term Risedronate on bone quality and bone turnover in women with postmenopausal osteoporosis","volume":"31","author":"Eriksen","year":"2002","journal-title":"Bone"},{"key":"10.1006\/ijom.2002.0472_RF11","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/BF01623000","article-title":"Bisphosphonates in osteoporosis: An introduction","volume":"3","author":"Fleich","year":"1993","journal-title":"Osteoporos Int"},{"key":"10.1006\/ijom.2002.0472_RF12","first-page":"23","article-title":"Bisphosphonates-history and experimental basis","volume":"8","author":"Fleisch","year":"1987","journal-title":"Bone"},{"key":"10.1006\/ijom.2002.0472_RF13","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/BF01623222","article-title":"New bisphosphonates in osteoporosis","volume":"2","author":"Fleisch","year":"1993","journal-title":"Osteoporosis Int"},{"key":"10.1006\/ijom.2002.0472_RF14","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/8756-3282(96)00085-3","article-title":"Time-dependent changes in biochemical bone markers and serum cholesterol in ovariectomized rats: Effect of raloxifene HCI, tamoxifen, estrogen, and alendronate","volume":"18","author":"Frolik","year":"1996","journal-title":"Bone"},{"key":"10.1006\/ijom.2002.0472_RF15","first-page":"283","article-title":"The biology of fracture healing: An overview for clinicians. Part I","volume":"248","author":"Frost","year":"1989","journal-title":"Clin Orthop"},{"key":"10.1006\/ijom.2002.0472_RF16","first-page":"294","article-title":"The biology of fracture healing: An overview for clinicians. Part II","volume":"48","author":"Frost","year":"1989","journal-title":"Clin Orthop"},{"key":"10.1006\/ijom.2002.0472_RF17","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/0022-3913(88)90408-8","article-title":"Preservation of alveolar ridge with hydroxyapatite-collagen implants in rats","volume":"60","author":"Hanne","year":"1988","journal-title":"J Prosthet Dent"},{"key":"10.1006\/ijom.2002.0472_RF18","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/S8756-3282(02)00870-0","article-title":"Effects of short-term alendronate treatment on the three-dimensional microstructural, physical, and mechanical properties of dog trabecular bone","volume":"31","author":"Hu","year":"2002","journal-title":"Bone"},{"key":"10.1006\/ijom.2002.0472_RF19","doi-asserted-by":"crossref","first-page":"1478","DOI":"10.1002\/jbmr.5650101008","article-title":"Bisphosphonates promote apoptosis in murine osteoclasts in vitro and in vivo","volume":"10","author":"Hughes","year":"1995","journal-title":"J Bone Miner Res"},{"key":"10.1006\/ijom.2002.0472_RF20","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/S0889-5406(94)70048-6","article-title":"Anchorage and retentive effects of a bisphosphonate (AHBuBP) on tooth movement in rats","volume":"106","author":"Igarashi","year":"1994","journal-title":"Am J Orthod Dentofacial Orthop"},{"key":"10.1006\/ijom.2002.0472_RF21","doi-asserted-by":"crossref","first-page":"1644","DOI":"10.1177\/00220345960750090501","article-title":"Inhibitory effect of the topical administration of a bisphosphonate (Risedronate) on root resorption incident to orthodontic tooth movement in rats","volume":"75","author":"Igarashi","year":"1996","journal-title":"J Dent Res"},{"key":"10.1006\/ijom.2002.0472_RF22","first-page":"234","article-title":"Current perspectives in residual ridge remodelling and its clinical implications: A review","volume":"80","author":"Jahangari","year":"1998","journal-title":"J Prosthet Dent"},{"key":"10.1006\/ijom.2002.0472_RF23","doi-asserted-by":"crossref","first-page":"415","DOI":"10.2165\/00003495-199753030-00006","article-title":"Alendronate: a review of its pharmacological properties and therapeutic efficacy in postmenopausal osteoporosis","volume":"53","author":"Jeal","year":"1997","journal-title":"Drugs"},{"key":"10.1006\/ijom.2002.0472_RF24","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF01623652","article-title":"Rationale for the use of alendronate in osteoporosis","volume":"5","author":"Kanis","year":"1995","journal-title":"Osteoporos Int"},{"key":"10.1006\/ijom.2002.0472_RF25","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1902\/jop.2000.71.5.790","article-title":"A histopathological investigation on the effects of the bisphosphonate alendronate on resorptive phase following mucoperiosteal flap surgery in the mandible of rats","volume":"71","author":"Kaynak","year":"2000","journal-title":"J Periodontol"},{"key":"10.1006\/ijom.2002.0472_RF26","first-page":"265","article-title":"Effects of bisphosphonate on the remodeling of rat sagittal suture after rapid expansion","volume":"71","author":"Kayou","year":"2001","journal-title":"Angle Orthod"},{"key":"10.1006\/ijom.2002.0472_RF27","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/S8756-3282(96)00364-X","article-title":"Alendronate in the treatment of Paget's disease of bone","volume":"20","author":"Khan","year":"1997","journal-title":"Bone"},{"key":"10.1006\/ijom.2002.0472_RF28","doi-asserted-by":"crossref","first-page":"2127","DOI":"10.1172\/JCI117901","article-title":"Comparison of alendronate and sodium flouride effect on cancellous and cortical bone in minipigs","volume":"95","author":"Lafage","year":"1995","journal-title":"J Clin Invest"},{"key":"10.1006\/ijom.2002.0472_RF29","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1902\/jop.1998.69.9.1044","article-title":"Preservation of alveolar bone in extraction sockets using bioabsorable membranes","volume":"69","author":"Lekowic","year":"1998","journal-title":"J Periodontol"},{"key":"10.1006\/ijom.2002.0472_RF30","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/8756-3282(96)00182-2","article-title":"Comparison of the distribution of 3H-Alendronate and 3HEtidronate in rat and mouse bones","volume":"19","author":"Masarachia","year":"1996","journal-title":"Bone"},{"key":"10.1006\/ijom.2002.0472_RF31","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1359\/jbmr.2000.15.4.613","article-title":"Suppressed bone turnover by bisphosphonates increases microdamage accumulation and reduces some biomechanical properties in dog rib","volume":"15","author":"Mashiba","year":"2000","journal-title":"J Bone Miner Res"},{"key":"10.1006\/ijom.2002.0472_RF32","first-page":"609","article-title":"Novel mutations in the a3 subunit of vacuolar H+-adenosine triphosphatase in a Japanese patient with infantile malignant osteopetrosis","volume":"28","author":"Michigami","year":"2002","journal-title":"Bone"},{"key":"10.1006\/ijom.2002.0472_RF33","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S8756-3282(96)90165-9","article-title":"Current bone mineral density data on bisphophonates in postmenopausal osteoporosis","volume":"19","author":"McClung","year":"1996","journal-title":"Bone"},{"key":"10.1006\/ijom.2002.0472_RF34","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/S0889-8529(02)00079-8","article-title":"Bisphosphonates","volume":"32","author":"McClung","year":"2003","journal-title":"Endocrinol Metab Clin North Am"},{"key":"10.1006\/ijom.2002.0472_RF35","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1034\/j.1600-0765.2001.036004244.x","article-title":"Effects of a bisphosphonate on the expression of bone specific genes after autogenous free bone grafting in rats","volume":"36","author":"Myoung","year":"2001","journal-title":"J Periodontal Res"},{"key":"10.1006\/ijom.2002.0472_RF36","first-page":"42","article-title":"Mineral binding affinities of bisphosphonates","volume":"30","author":"Nancollas","year":"2002","journal-title":"Bone"},{"key":"10.1006\/ijom.2002.0472_RF37","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1359\/jbmr.1997.12.7.1116","article-title":"Specific inhibitors of vaocular H+-ATPase trigger apoptotic cell death of osteoclasts","volume":"12","author":"Okahashi","year":"1997","journal-title":"J Bone Miner Res"},{"key":"10.1006\/ijom.2002.0472_RF38","first-page":"13","article-title":"Preprosthetic surgery: prevention of the alveolar process using retained tooth roots","volume":"12","author":"Ortega","year":"1991","journal-title":"Pract Odontol"},{"key":"10.1006\/ijom.2002.0472_RF39","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1002\/(SICI)1097-4652(199707)172:1<79::AID-JCP9>3.0.CO;2-A","article-title":"Osteoclast activation: Potent inhibition by the bisphosphonate alendronate through a nonresorptive mechanism","volume":"172","author":"Owens","year":"1997","journal-title":"J Cell Physiol"},{"key":"10.1006\/ijom.2002.0472_RF40","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1172\/JCI6800","article-title":"Prevention of osteocyte and osteoblast apoptosis by bisphosphonates and calcitonin","volume":"104","author":"Plotkin","year":"1999","journal-title":"J Clin Invest"},{"key":"10.1006\/ijom.2002.0472_RF41","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/S8756-3282(01)00665-2","article-title":"Association between pharmacokinetics of oral ibandronate and clinical response in bone mass and bone turnover in women with postmenopausal osteoporosis","volume":"30","author":"Ravn","year":"2002","journal-title":"Bone"},{"key":"10.1006\/ijom.2002.0472_RF42","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1902\/jop.1995.66.3.211","article-title":"Alendronate treatment of naturally occurring periodontitis in beagle dogs","volume":"66","author":"Reddy","year":"1995","journal-title":"J Periodontol"},{"key":"10.1006\/ijom.2002.0472_RF43","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1056\/NEJMoa011807","article-title":"Intravenous zoledronic acid in postmenopausal women with low bone mineral density","volume":"346","author":"Reid","year":"2002","journal-title":"N Engl J Med"},{"key":"10.1006\/ijom.2002.0472_RF44","doi-asserted-by":"crossref","first-page":"2692","DOI":"10.1172\/JCI118722","article-title":"Bisphosphonate: Mechanism of action","volume":"97","author":"Rodan","year":"1996","journal-title":"J Clin Invest"},{"key":"10.1006\/ijom.2002.0472_RF45","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S8756-3282(96)00318-3","article-title":"Bone mass homeostasis and bisphosphonate action","volume":"20","author":"Rodan","year":"1997","journal-title":"Bone"},{"key":"10.1006\/ijom.2002.0472_RF46","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/S8756-3282(97)00018-5","article-title":"Mineralization of cancellous bone after alendronate and sodium fluoride treatment: A quantitative backscattered electron imaging study on minipig ribs","volume":"20","author":"Roschger","year":"1997","journal-title":"Bone"},{"key":"10.1006\/ijom.2002.0472_RF47","doi-asserted-by":"crossref","first-page":"2004","DOI":"10.1172\/JCI116422","article-title":"Bisphosphonates act on rat bone resorption through the mediation of osteoblasts","volume":"91","author":"Sahni","year":"1993","journal-title":"J Clin Invest"},{"key":"10.1006\/ijom.2002.0472_RF48","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/S8756-3282(97)00071-9","article-title":"Alendronate prevents cyclosporin A induced osteopenia in the rat","volume":"21","author":"Sass","year":"1997","journal-title":"Bone"},{"key":"10.1006\/ijom.2002.0472_RF49","series-title":"A Textbook of Oral Surgery","author":"Shafer","year":"1974"},{"key":"10.1006\/ijom.2002.0472_RF50","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1093\/oxfordjournals.jmicro.a023623","article-title":"Bone wound healing after maxillary molar extraction in ovariectomized aged rats","volume":"47","author":"Shimizu","year":"1998","journal-title":"J Electron Microsc (Tokyo)"},{"key":"10.1006\/ijom.2002.0472_RF51","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/0014-4827(88)90191-7","article-title":"Microelectrode studies on the acid micromovement beneath adherent macrophages and osteoclasts","volume":"175","author":"Silver","year":"1988","journal-title":"Exp Cell Res"},{"key":"10.1006\/ijom.2002.0472_RF52","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1210\/jc.81.3.961","article-title":"Comparative study of alendronate versus etidronate for the treatment of Paget's disease of bone","volume":"81","author":"Siris","year":"1996","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1006\/ijom.2002.0472_RF53","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/S8756-3282(03)00024-3","article-title":"Involvement of vacuolar H+-ATPase in incorporation of risedronate into osteoclasts","volume":"32","author":"Takami","year":"2003","journal-title":"Bone"},{"key":"10.1006\/ijom.2002.0472_RF54","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1016\/S0002-9343(96)00282-3","article-title":"Effect of three years of oral alendronate treatment in postmenopausal women with osteoporosis","volume":"101","author":"Tucci","year":"1996","journal-title":"Am J Med"},{"key":"10.1006\/ijom.2002.0472_RF55","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/S8756-3282(97)00006-9","article-title":"Effect of alendronate treatment on the osteoclastogenic potential of bone marrow cells in mice","volume":"20","author":"Van Beek","year":"1997","journal-title":"Bone"},{"key":"10.1006\/ijom.2002.0472_RF56","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/S8756-3282(01)00655-X","volume":"30","author":"Van Beek","year":"2002","journal-title":"Bone"},{"key":"10.1006\/ijom.2002.0472_RF57","first-page":"292","article-title":"Effects of local injection with bisphosphonate (HEBT) on experimental tooth movement","volume":"51","author":"Warita","year":"1992","journal-title":"J Jpn Orthod Soc"},{"key":"10.1006\/ijom.2002.0472_RF58","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1111\/j.1600-0765.1994.tb01088.x","article-title":"Histomorphometrical analysis of the effects of the bisphosphonate alendronate on bone loss caused by experimental periodontitis in monkeys","volume":"29","author":"Weinreb","year":"1994","journal-title":"J Periodontal Res"},{"key":"10.1006\/ijom.2002.0472_RF59","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1172\/JCI0214538","article-title":"Promotion of osteoclast survival and antagonism of bisphosphonate-induced osteoclast apoptosis by glucocorticoids","volume":"109","author":"Weinstein","year":"2002","journal-title":"J Clin Invest"},{"key":"10.1006\/ijom.2002.0472_RF60","first-page":"17","article-title":"Preservation of the alveolar ridge at implant sides","volume":"20","author":"Wiesen","year":"1998","journal-title":"Periodontol Clin Investig"},{"key":"10.1006\/ijom.2002.0472_RF61","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1902\/jop.1989.60.9.485","article-title":"Altering the progression of human alveolar bone loss with the non-steroidal anti-inflammatory drug flurbiprofen","volume":"60","author":"Williams","year":"1989","journal-title":"J Periodontol"},{"key":"10.1006\/ijom.2002.0472_RF62","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1902\/jop.1997.68.9.884","article-title":"Local delivery of an amino biphosphonate prevents the resorptive phase of alveolar bone following mucoperiosteal flap surgery in rats","volume":"68","author":"Yaffe","year":"1997","journal-title":"J Periodontol"}],"container-title":["International Journal of Oral and Maxillofacial Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0901502702904728?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0901502702904728?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,2,13]],"date-time":"2019-02-13T21:57:24Z","timestamp":1550095044000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0901502702904728"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,4]]},"references-count":62,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2004,4]]}},"alternative-id":["S0901502702904728"],"URL":"https:\/\/doi.org\/10.1006\/ijom.2002.0472","relation":{},"ISSN":["0901-5027"],"issn-type":[{"value":"0901-5027","type":"print"}],"subject":[],"published":{"date-parts":[[2004,4]]}}}