{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T04:13:08Z","timestamp":1790395988507,"version":"4.1.0"},"reference-count":86,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2000,2,1]],"date-time":"2000-02-01T00:00:00Z","timestamp":949363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2000,2,1]],"date-time":"2000-02-01T00:00:00Z","timestamp":949363200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Autoimmunity"],"published-print":{"date-parts":[[2000,2]]},"DOI":"10.1006\/jaut.1999.0343","type":"journal-article","created":{"date-parts":[[2002,10,6]],"date-time":"2002-10-06T16:34:52Z","timestamp":1033922092000},"page":"63-78","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":135,"title":["CD69, HLA-DR and the IL-2R Identify Persistently Activated T Cells in Psoriasis Vulgaris Lesional Skin: Blood and Skin Comparisons by Flow Cytometry"],"prefix":"10.1006","volume":"14","author":[{"given":"K","family":"Ferenczi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L","family":"Burack","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Pope","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.G","family":"Krueger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.M","family":"Austin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1006\/jaut.1999.0343_RF1","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1016\/S0190-9622(89)80200-2","article-title":"Remission of psoriatic lesions with muromonab-CD3 (Orthoclone OKT3) treatment","volume":"20","author":"Weinshenker","year":"1989","journal-title":"J. Am. Acad. Dermatol."},{"key":"10.1006\/jaut.1999.0343_RF2","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1038\/nm0595-442","article-title":"Response of psoriasis to a lymphocyte-selective toxin (DAB389IL-2) suggests a primary immune, but not keratinocyte, pathogenic basis","author":"Gottlieb","year":"1995","journal-title":"Nature Med."},{"key":"10.1006\/jaut.1999.0343_RF3","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1172\/JCI5857","article-title":"CTLA4Ig-mediated blockade of T-cell costimulation in patients with psoriasis vulgaris","volume":"103","author":"Abrams","year":"1999","journal-title":"J. Clin. Invest."},{"key":"10.1006\/jaut.1999.0343_RF4","series-title":"Therapy of Moderate-to-Severe psoriasis","first-page":"39","article-title":"PUVA bath therapy with 8-methoxypsoralen","author":"Vallat","year":"1993"},{"key":"10.1006\/jaut.1999.0343_RF5","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1001\/archderm.134.10.1263","article-title":"Trimethylpsoralen bath PUVA is a remittive treatment for psoriasis vulgaris. Evidence that epidermal immunocytes are direct therapeutic targets","volume":"134","author":"Coven","year":"1998","journal-title":"Arch. Dermatol."},{"key":"10.1006\/jaut.1999.0343_RF6","doi-asserted-by":"crossref","first-page":"1514","DOI":"10.1001\/archderm.1997.03890480034005","article-title":"Narrowband UV-B produces superior clinical and histopathological resolution of moderate-to-severe psoriasis in patients compared with broadband UV-B","volume":"133","author":"Coven","year":"1997","journal-title":"Arch. Dermatol."},{"key":"10.1006\/jaut.1999.0343_RF7","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1084\/jem.189.4.711","article-title":"312-nanometer Ultraviolet B light (narrow-band UVB) induces apoptosis of T cells within psoriatic lesions","volume":"189","author":"Ozawa","year":"1999","journal-title":"J. Exp. Med."},{"key":"10.1006\/jaut.1999.0343_RF8","doi-asserted-by":"crossref","first-page":"3110","DOI":"10.1001\/jama.1986.03380220076026","article-title":"Cyclosporine improves psoriasis in a double-blind study","volume":"256","author":"Ellis","year":"1986","journal-title":"J. Amer. Med. Assoc."},{"key":"10.1006\/jaut.1999.0343_RF9","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1111\/j.1365-2133.1987.tb05869.x","article-title":"The effects of cyclosporin A on T lymphocyte and dendritic cell sub-populations in psoriasis","volume":"116","author":"Baker","year":"1987","journal-title":"Brit. J. Dermatol."},{"key":"10.1006\/jaut.1999.0343_RF10","first-page":"3322","article-title":"FK 506: a new therapeutic agent for severe recalcitrant psoriasis","volume":"23","author":"Abu-Elmagd","year":"1991","journal-title":"Transplant. Proc."},{"key":"10.1006\/jaut.1999.0343_RF11","first-page":"3330","article-title":"Influence of FK 506 on T lymphocytes, Langerhans' cells and the expression of cytokine receptors and adhesion molecules in psoriatic skin lesions: a preliminary study","volume":"23","author":"Thomson","year":"1991","journal-title":"Transplant. Proc."},{"key":"10.1006\/jaut.1999.0343_RF12","first-page":"3325","article-title":"Metabolic effects of FK 506 in patients with severe psoriasis: short-term follow-up of seven cases","volume":"23","author":"Nikolaidis","year":"1991","journal-title":"Transplant. Proc."},{"key":"10.1006\/jaut.1999.0343_RF13","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/BF00431054","article-title":"Lymphocytes and macrophages of the epidermis and dermis in lesional psoriatic skin, but not epidermal Langerhans cells, are depleted by treatment with cyclosporin A","volume":"281","author":"Gupta","year":"1989","journal-title":"Arch. Dermatol. Res."},{"key":"10.1006\/jaut.1999.0343_RF14","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1126\/science.2785715","article-title":"Interleukin-2 receptor beta chain gene: generation of the three receptor forms by cloned human alpha and beta chain cDNAs","volume":"244","author":"Hatakeyama","year":"1989","journal-title":"Science"},{"key":"10.1006\/jaut.1999.0343_RF15","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1016\/0092-8674(89)90607-7","article-title":"A restricted cytoplasmic region of IL-2 receptor beta chain is essential for growth signal transduction but not for ligand binding and internalization","volume":"59","author":"Hatakeyama","year":"1989","journal-title":"Cell"},{"key":"10.1006\/jaut.1999.0343_RF16","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1007\/BF00431219","article-title":"Expression of a Hodgkin and Reed-Sternberg cell associated antigen (Ki- 1) in cutaneous lymphoid infiltrates","volume":"279","author":"Ralfkiaer","year":"1987","journal-title":"Arch. Dermatol. Res."},{"key":"10.1006\/jaut.1999.0343_RF17","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1146\/annurev.iy.12.040194.001303","article-title":"Lymphokine production by human T cells in disease states","volume":"12","author":"Romagnani","year":"1994","journal-title":"Ann. Rev. Immunol."},{"key":"10.1006\/jaut.1999.0343_RF18","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1096\/fasebj.9.1.7821763","article-title":"Preferential expression of CD30 by human CD4+ T cells producing Th2-type cytokines","volume":"9","author":"Del Prete","year":"1995","journal-title":"FASEB J."},{"key":"10.1006\/jaut.1999.0343_RF19","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1165\/ajrcmb.17.3.2797","article-title":"Allergen-induced cytokine production in atopic disease and its relationship to disease severity","volume":"17","author":"Leonard","year":"1997","journal-title":"Amer. J. Resp. Cell & Mol. Biol."},{"key":"10.1006\/jaut.1999.0343_RF20","doi-asserted-by":"crossref","first-page":"2407","DOI":"10.1084\/jem.180.6.2407","article-title":"CD30 expression by CD8+ T cells producing type 2 helper cytokines. Evidence for large numbers of CD8+CD30+ T cell clones in human immunodeficiency virus infection","volume":"180","author":"Manetti","year":"1994","journal-title":"J. Exp. Med."},{"key":"10.1006\/jaut.1999.0343_RF21","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1111\/j.1600-065X.1990.tb00564.x","article-title":"Leukocyte adhesion molecules deficiency: its structural basis, pathophysiology and implications for modulating the inflammatory response","volume":"114","author":"Arnaout","year":"1990","journal-title":"Immunol. Rev."},{"key":"10.1006\/jaut.1999.0343_RF22","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1038\/346425a0","article-title":"Adhesions receptors of the immune system","volume":"346","author":"Springer","year":"1990","journal-title":"Nature"},{"key":"10.1006\/jaut.1999.0343_RF23","doi-asserted-by":"crossref","first-page":"1876","DOI":"10.1084\/jem.164.6.1876","article-title":"Adhesion-promoting receptors on human macrophages recognize Escherichia coli by binding to lipopolysaccharide","volume":"164","author":"Wright","year":"1986","journal-title":"J. Exp. Med."},{"key":"10.1006\/jaut.1999.0343_RF24","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1084\/jem.165.1.195","article-title":"Role of the adherence-promoting receptors, CR3, LFA-1 and p150,95, in binding of Histoplasma capsulatum by human macrophages","volume":"165","author":"Bullock","year":"1987","journal-title":"J. Exp. Med."},{"key":"10.1006\/jaut.1999.0343_RF25","doi-asserted-by":"crossref","first-page":"2785","DOI":"10.4049\/jimmunol.135.4.2785","article-title":"The mouse macrophage receptor for C3bi (CR3) is a major mechanism in the phagocytosis of Leishmania promastigotes","volume":"135","author":"Mosser","year":"1985","journal-title":"J. Immunol."},{"key":"10.1006\/jaut.1999.0343_RF26","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1084\/jem.168.1.279","article-title":"Complement receptor type 3 (CR3) binds to an Arg-Gly-Asp-containing region of the major surface glycoprotein, gp63, of Leishmania promastigotes","volume":"168","author":"Russell","year":"1988","journal-title":"J. Exp. Med."},{"key":"10.1006\/jaut.1999.0343_RF27","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/BF00510050","article-title":"Immunocompetent cells in psoriasis. In situ immunophenotyping by monoclonal antibodies","volume":"275","author":"Bos","year":"1983","journal-title":"Arch. Dermatol. Res."},{"key":"10.1006\/jaut.1999.0343_RF28","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1111\/j.1365-2133.1984.tb04678.x","article-title":"Epidermal T lymphocytes and HLA-DR expression in psoriasis","volume":"110","author":"Baker","year":"1984","journal-title":"Br. J. Dermatol."},{"key":"10.1006\/jaut.1999.0343_RF29","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1084\/jem.164.4.1013","article-title":"Expression of HLA-DR molecules by keratinocytes and presence of Langerhans cells in the dermal infiltrate of active psoriatic plaques","volume":"164","author":"Gottlieb","year":"1986","journal-title":"J. Exp. Med."},{"key":"10.1006\/jaut.1999.0343_RF30","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1002\/path.1711740203","article-title":"Assessment of epidermal dendritic cell markers and T-lymphocytes in psoriasis","volume":"174","author":"Jones","year":"1994","journal-title":"J. Path."},{"key":"10.1006\/jaut.1999.0343_RF31","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/S0190-9622(89)70073-6","article-title":"Characterization of intercellular adhesion molecule-1 and HLA-DR expression in normal and inflamed skin: Modulation by recombinant gamma interferon and tumor necrosis factor","volume":"20","author":"Griffiths","year":"1989","journal-title":"J. Amer. Acad. Dermatol."},{"key":"10.1006\/jaut.1999.0343_RF32","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/BF00370733","article-title":"Reappraisal of in situ immunophenotypic analysis of psoriasis skin: interaction of activated HLA-DR+immunocompetent cells and endothelial cells is a major feature of psoriatic lesions","volume":"286","author":"de Boer","year":"1994","journal-title":"Arch. Dermatol. Res."},{"key":"10.1006\/jaut.1999.0343_RF33","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1111\/j.1600-0560.1998.tb01694.x","article-title":"Intraepidermal lymphocytes in psoriatic lesions are activated GMP-17 (TIA-1)+CD8+CD3+CTLs as determined by phenotypic analysis","volume":"25","author":"Austin","year":"1998","journal-title":"J. Cutan. Pathol."},{"key":"10.1006\/jaut.1999.0343_RF34","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1111\/1523-1747.ep12613452","article-title":"Both dendritic cells and memory T lymphocytes emigrate from organ cultures of human skin and form distinctive dendritic-T-cell conjugates","volume":"104","author":"Pope","year":"1995","journal-title":"J. Invest. Dermatol."},{"key":"10.1006\/jaut.1999.0343_RF35","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1002\/eji.1830170725","article-title":"CD3+WT31- peripheral T lymphocytes lack T44 (CD28), a surface molecule involved in activation of T cells bearing the alpha\/beta heterodimer","volume":"17","author":"Poggi","year":"1987","journal-title":"Eur. J. Immunol."},{"key":"10.1006\/jaut.1999.0343_RF36","author":"Austin","year":"1999","journal-title":"J. Invest. Dermatol. in press"},{"key":"10.1006\/jaut.1999.0343_RF37","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.4049\/jimmunol.143.4.1123","article-title":"T cell activation via Leu-23 (CD69)","volume":"143","author":"Testi","year":"1989","journal-title":"J. Immunol."},{"key":"10.1006\/jaut.1999.0343_RF38","doi-asserted-by":"crossref","first-page":"1854","DOI":"10.4049\/jimmunol.142.6.1854","article-title":"Leu 23 induction as an early marker of functional CD3\/T cell antigen receptor triggering. Requirement for receptor cross-linking, prolonged elevation of intracellular [Ca++] and stimulation of protein kinase C","volume":"142","author":"Testi","year":"1989","journal-title":"J. Immunol."},{"key":"10.1006\/jaut.1999.0343_RF39","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1002\/(SICI)1097-0320(19970101)27:1<71::AID-CYTO9>3.0.CO;2-O","article-title":"Flow cytometric analysis of activation markers on stimulated T cells and their correlation with cell proliferation","volume":"27","author":"Caruso","year":"1997","journal-title":"Cytometry"},{"key":"10.1006\/jaut.1999.0343_RF40","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1111\/1523-1747.ep12506332","article-title":"Expression of HLA-DR antigen in skin from patients with psoriasis","volume":"78","author":"Morhenn","year":"1982","journal-title":"J. Invest. Dermatol."},{"key":"10.1006\/jaut.1999.0343_RF41","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/BF00510050","article-title":"Immunocompetent cells in psoriasis. In situ immunophenotyping by monoclonal antibodies","volume":"275","author":"Bos","year":"1983","journal-title":"Arch. Dermatol. Res."},{"key":"10.1006\/jaut.1999.0343_RF42","first-page":"413","article-title":"Characterization and regulation of CD69 expression on rheumatoid arthritis synovial fluid T cells","volume":"22","author":"Fernandez-Gutierrez","year":"1995","journal-title":"J. Rheumatol."},{"key":"10.1006\/jaut.1999.0343_RF43","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1111\/j.1365-3083.1989.tb01167.x","article-title":"Expression of activation markers on CD4+ and CD8+ cells from synovial fluid, synovial tissue and peripheral blood of patients with inflammatory arthritides","volume":"29","author":"Hovdenes","year":"1989","journal-title":"Scand. J. Immunol."},{"key":"10.1006\/jaut.1999.0343_RF44","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1046\/j.1365-2613.1997.290360.x","article-title":"Coexpression of CD69 and HLADR activation markers on synovial fluid T lymphocytes of patients affected by rheumatoid arthritis: a three-colour cytometric analysis","volume":"78","author":"Afeltra","year":"1997","journal-title":"Int. J. Exp. Pathol."},{"key":"10.1006\/jaut.1999.0343_RF45","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S0198-8859(97)00111-0","article-title":"Down-regulation of CD25 expression on the surface of activated tumor-infiltrating lymphocytes in human cervical carcinoma","volume":"56","author":"Sheu","year":"1997","journal-title":"Hum. Immunol."},{"key":"10.1006\/jaut.1999.0343_RF46","doi-asserted-by":"crossref","first-page":"2580","DOI":"10.1182\/blood.V83.9.2580.2580","article-title":"T lymphocytes in skin lesions of psoriasis and mycosis fungoides express B7-1: A ligand for CD28","volume":"83","author":"Nickoloff","year":"1994","journal-title":"Blood"},{"key":"10.1006\/jaut.1999.0343_RF47","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1172\/JCI117308","article-title":"Characterization of dermal dendritic cells in psoriasis. Autostimulation of T lymphocytes and induction of Th1 type cytokines","volume":"94","author":"Nestle","year":"1994","journal-title":"J. Clin. Invest."},{"key":"10.1006\/jaut.1999.0343_RF48","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1006\/jaut.1996.0053","article-title":"Islet-infiltrating T lymphocytes in insulin-dependent diabetic patients express CD80 (B7-1) and CD86 (B7-2)","volume":"9","author":"Imagawa","year":"1996","journal-title":"J. Autoimmun."},{"key":"10.1006\/jaut.1999.0343_RF49","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1111\/1523-1747.ep12371679","article-title":"The cytokine network in lesional and lesion-free psoriatic skin is characterized by a T-helper type 1 cell-mediated response","volume":"101","author":"Uyemura","year":"1993","journal-title":"J. Invest. Dermatol."},{"key":"10.1006\/jaut.1999.0343_RF50","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1111\/1523-1747.ep12371752","article-title":"T cells involved in psoriasis vulgaris belong to the Th 1 subset","volume":"102","author":"Schlaak","year":"1994","journal-title":"J. Invest. Dermatol."},{"key":"10.1006\/jaut.1999.0343_RF51","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1172\/JCI1476","article-title":"IL-10 is a key cytokine in psoriasis","volume":"101","author":"Asadullah","year":"1998","journal-title":"J. Clin. Invest."},{"key":"10.1006\/jaut.1999.0343_RF52","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1111\/j.1365-2249.1995.tb03851.x","article-title":"High levels of the soluble form of CD30 molecule in rheumatoid arthritis (RA) are expression of CD30+ T cell involvement in the inflamed joints","volume":"102","author":"Gerli","year":"1995","journal-title":"Clin. Exp. Immunol."},{"key":"10.1006\/jaut.1999.0343_RF53","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1002\/1529-0131(199809)41:9<1669::AID-ART19>3.0.CO;2-G","article-title":"Flow cytometric single-cell analysis of cytokine production by CD4+ T cells in synovial tissue and peripheral blood from patients with rheumatoid arthritis","volume":"41","author":"Morita","year":"1998","journal-title":"Arth. Rheum."},{"key":"10.1006\/jaut.1999.0343_RF54","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1001\/archderm.1992.01680160079008","article-title":"Circulating activated T lymphocytes in autoeczematization","volume":"128","author":"Kasteler","year":"1992","journal-title":"Arch. Dermatol."},{"key":"10.1006\/jaut.1999.0343_RF55","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1111\/1523-1747.ep12325496","article-title":"Elevated numbers of proliferating mononuclear cells in the peripheral blood of psoriatic patients correlate with disease severity","volume":"105","author":"Jeffes","year":"1995","journal-title":"J. Invest. Dermatol."},{"key":"10.1006\/jaut.1999.0343_RF56","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1111\/j.1365-2133.1984.tb07309.x","article-title":"T-cell subpopulations in the blood and skin of patients with psoriasis","volume":"110","author":"Baker","year":"1984","journal-title":"Br. J. Dermatol."},{"key":"10.1006\/jaut.1999.0343_RF57","doi-asserted-by":"crossref","first-page":"422","DOI":"10.2340\/0001555563422424","article-title":"An analysis of T-lymphocyte subpopulations in psoriasis using monoclonal antibodies","volume":"63","author":"Kokelj","year":"1983","journal-title":"Acta. Derm. Venereol. (Stockh)"},{"key":"10.1006\/jaut.1999.0343_RF58","doi-asserted-by":"crossref","first-page":"2204","DOI":"10.1210\/jcem.83.6.4889","article-title":"Increased CD69 and human leukocyte antigen-DR expression on T lymphocytes in insulin-dependent diabetes mellitus of long standing","volume":"83","author":"Gessl","year":"1998","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1006\/jaut.1999.0343_RF59","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1006\/clin.1998.4524","article-title":"Elevated CD69 expression on naive peripheral blood T-cells in hyperthyroid Graves' disease and autoimmune thyroiditis: discordant effect of methimazole on HLA-DR and CD69","volume":"87","author":"Gessl","year":"1998","journal-title":"Clin. Immunol. Immunopathol."},{"key":"10.1006\/jaut.1999.0343_RF60","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1046\/j.1365-3083.1998.00366.x","article-title":"Participation of the CD69 antigen in the T-cell activation process of patients with systemic lupus erythematosus","volume":"48","author":"Crispin","year":"1998","journal-title":"Scand. J. Immunol."},{"key":"10.1006\/jaut.1999.0343_RF61","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1083\/jcb.129.1.55","article-title":"Endocytosis of interleukin 2 receptors in human T lymphocytes: distinct intracellular localization and fate of the receptor alpha, beta and gamma chains","volume":"129","author":"Hemar","year":"1995","journal-title":"J. Cell. Biol."},{"key":"10.1006\/jaut.1999.0343_RF62","doi-asserted-by":"crossref","first-page":"1811","DOI":"10.1001\/archderm.1988.01670120027005","article-title":"Interleukin 2 and psoriasis","volume":"124","author":"Lee","year":"1988","journal-title":"Arch. Dermatol."},{"key":"10.1006\/jaut.1999.0343_RF63","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/S0923-1811(96)00517-8","article-title":"Psoriasis: comparison of immunological markers in patients with acute and remission phase","volume":"13","author":"De Pita","year":"1996","journal-title":"J. Dermatol. Sci."},{"key":"10.1006\/jaut.1999.0343_RF64","doi-asserted-by":"crossref","first-page":"9282","DOI":"10.1073\/pnas.91.20.9282","article-title":"CD8+ T cells in psoriatic lesions preferentially use T-cell receptor V\u03b23 and\/or V\u03b213.1 genes","volume":"91","author":"Chang","year":"1994","journal-title":"PNAS J."},{"key":"10.1006\/jaut.1999.0343_RF65","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1093\/infdis\/155.2.247","article-title":"Compartmentalization of cells bearing \u2018rheumatic\u2019 cell surface antigens in peripheral blood and tonsils in rheumatic heart disease","volume":"155","author":"Gray","year":"1987","journal-title":"J. Infect. Dis."},{"key":"10.1006\/jaut.1999.0343_RF66","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1084\/jem.186.9.1407","article-title":"Phenotypic and functional separation of memory and effector human CD8+ T cells","volume":"186","author":"Hamann","year":"1997","journal-title":"J. Exp. Med."},{"key":"10.1006\/jaut.1999.0343_RF67","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/S0165-2478(97)00132-6","article-title":"Flow cytometric detection of perforin in normal human lymphocyte subpopulations defined by expression of activation\/differentiation antigens","volume":"60","author":"Rutella","year":"1998","journal-title":"Immunol. Lett."},{"key":"10.1006\/jaut.1999.0343_RF68","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1182\/blood.V67.4.1007.1007","article-title":"Monoclonal antibody-defined functional epitopes on the adhesion-promoting glycoprotein complex (CDw 18) of human neutrophils","volume":"67","author":"Wallis","year":"1986","journal-title":"Blood"},{"key":"10.1006\/jaut.1999.0343_RF69","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1159\/000249184","article-title":"Intraepidermal accumulation of polymorphonuclear leukocytes in chronic stable plaque psoriasis","volume":"174","author":"van de Kerkhof","year":"1987","journal-title":"Dermatologica"},{"key":"10.1006\/jaut.1999.0343_RF70","doi-asserted-by":"crossref","first-page":"1893","DOI":"10.1083\/jcb.107.5.1893","article-title":"Oligospecificity of the cellular adhesion receptor Mac-1 encompasses an inducible recognition specificity for fibrinogen","volume":"107","author":"Altieri","year":"1988","journal-title":"J. Cell. Biol."},{"key":"10.1006\/jaut.1999.0343_RF71","doi-asserted-by":"crossref","first-page":"1473","DOI":"10.1083\/jcb.130.6.1473","article-title":"Heparin is an adhesive ligand for the leukocyte integrin Mac-1 (CD11b\/CD1)","volume":"130","author":"Diamond","year":"1995","journal-title":"J. Cell. Biol."},{"key":"10.1006\/jaut.1999.0343_RF72","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1038\/311626a0","article-title":"Molecular cloning and expression of cDNAs for the human interleukin 2 receptor","volume":"311","author":"Leonard","year":"1984","journal-title":"Nature"},{"key":"10.1006\/jaut.1999.0343_RF73","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1084\/jem.158.4.1332","article-title":"Direct demonstration of the identity of T cell growth factor binding protein and the Tac antigen","volume":"158","author":"Robb","year":"1983","journal-title":"J. Exp. Med."},{"key":"10.1006\/jaut.1999.0343_RF74","doi-asserted-by":"crossref","unstructured":"Sharon, M. Klausner, R.D. Cullen, B.R. Chizzonite, R. Leonard, W.J. 1986, Novel interleukin-2 receptor subunit detected by cross-linking under high-affinity conditions. Science, 234, 859, 863","DOI":"10.1126\/science.3095922"},{"key":"10.1006\/jaut.1999.0343_RF75","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1084\/jem.162.3.823","article-title":"Involvement of T44 molecules in an antigen-independent pathway of T cell activation. Analysis of the correlations to the T cell antigen-receptor complex","volume":"162","author":"Moretta","year":"1985","journal-title":"J. Exp. Med."},{"key":"10.1006\/jaut.1999.0343_RF76","doi-asserted-by":"crossref","first-page":"1988","DOI":"10.1084\/jem.164.6.1988","article-title":"Human T cell activation III. Rapid induction of a phosphorylated 28kD\/32kD disulfide-linked Early Activation (EA-1) by 12-o-tetrdeanoyl phorbol-13-acetate, mitogens, and antigens","volume":"164","author":"Hara","year":"1986","journal-title":"J. Exp. Med"},{"key":"10.1006\/jaut.1999.0343_RF77","doi-asserted-by":"crossref","first-page":"823","DOI":"10.4049\/jimmunol.128.2.823","article-title":"B lymphoblast antigen (BB-1) expressed on Epstein-Barr virus-activated B cell blasts, B lymphoblastoid cell lines, and Burkitt\u2019s lymphomas","volume":"128","author":"Yokochi","year":"1982","journal-title":"J. Immunol"},{"key":"10.1006\/jaut.1999.0343_RF78","doi-asserted-by":"crossref","first-page":"4494","DOI":"10.1073\/pnas.83.12.4494","article-title":"Activation of human B cells mediated through two distinct cell surface differentiation antigens, Bp35 and Bp50","volume":"83","author":"Clark","year":"1986","journal-title":"Proc. Natl. Acad. Sci U S A"},{"key":"10.1006\/jaut.1999.0343_RF79","doi-asserted-by":"crossref","first-page":"1841","DOI":"10.1084\/jem.180.5.1841","article-title":"B70\/B7-2 is identical to CD86 and is the mamor funtional ligand for CD28 expressed on human dendritic cells","volume":"180","author":"Caux","year":"1994","journal-title":"J. Exp. Med."},{"key":"10.1006\/jaut.1999.0343_RF80","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1038\/328267a0","article-title":"A new member of the immunoglobulin superfamily \u2014 CTLA-4","volume":"328","author":"Brunet","year":"1987","journal-title":"Nature"},{"key":"10.1006\/jaut.1999.0343_RF81","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.1002\/eji.1830181206","article-title":"Human Ig superfamily CTLA-4 gene: chromosomal localization and identity of protein sequence between murine and human CTLA-4 cytoplasmic domains","volume":"18","author":"Dariavach","year":"1988","journal-title":"Eur. J. Immunol."},{"key":"10.1006\/jaut.1999.0343_RF82","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1002\/hon.2900010105","article-title":"Evidence for the detection of the normal counterpart of Hodgkin and Sternberg-Reed cells","volume":"1","author":"Stein","year":"1983","journal-title":"Hematol. Oncol"},{"key":"10.1006\/jaut.1999.0343_RF83","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1002\/eji.1830090410","article-title":"Mac-1: a macrophage differentiation antigen identified by monoclonal antibody","volume":"9","author":"Springer","year":"1979","journal-title":"Eur. J. Immunol"},{"key":"10.1006\/jaut.1999.0343_RF84","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.1084\/jem.154.5.1517","article-title":"Molecular complexity of leukocyte surface glycoproteins related to the macrophage differentiation antigen Mac-1","volume":"154","author":"Trowbridge","year":"1981","journal-title":"J. Exp. Med."},{"key":"10.1006\/jaut.1999.0343_RF85","first-page":"948","article-title":"6-thioguanine induces selective apoptosis in lymphocytes -remittive anti-psoriatic effects correlate with depletion of activated lymphocytes from lesional skin","volume":"106","author":"Coven","year":"1996","journal-title":"J. Invest. Dermatol."},{"key":"10.1006\/jaut.1999.0343_RF86","first-page":"679","article-title":"Phase 1 trial of psoriasis with an anti-CD11A (LFA-1) monoclonal antibody (MAB)","volume":"110","author":"Gottlieb","year":"1998","journal-title":"J. Invest. Dermatol"}],"container-title":["Journal of Autoimmunity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0896841199903438?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0896841199903438?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,12]],"date-time":"2025-10-12T07:51:19Z","timestamp":1760255479000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0896841199903438"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,2]]},"references-count":86,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2000,2]]}},"alternative-id":["S0896841199903438"],"URL":"https:\/\/doi.org\/10.1006\/jaut.1999.0343","relation":{},"ISSN":["0896-8411"],"issn-type":[{"value":"0896-8411","type":"print"}],"subject":[],"published":{"date-parts":[[2000,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"CD69, HLA-DR and the IL-2R Identify Persistently Activated T Cells in Psoriasis Vulgaris Lesional Skin: Blood and Skin Comparisons by Flow Cytometry","name":"articletitle","label":"Article Title"},{"value":"Journal of Autoimmunity","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1006\/jaut.1999.0343","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2000 Academic Press. All rights reserved.","name":"copyright","label":"Copyright"}]}}