{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T15:06:32Z","timestamp":1791126392006,"version":"4.1.0"},"reference-count":34,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2000,6,1]],"date-time":"2000-06-01T00:00:00Z","timestamp":959817600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Molecular Biology"],"published-print":{"date-parts":[[2000,6]]},"DOI":"10.1006\/jmbi.2000.3816","type":"journal-article","created":{"date-parts":[[2002,9,18]],"date-time":"2002-09-18T19:24:54Z","timestamp":1032377094000},"page":"1341-1351","source":"Crossref","is-referenced-by-count":102,"title":["NMR characterization of residual structure in the denatured state of protein L"],"prefix":"10.1006","volume":"299","author":[{"given":"Qian","family":"Yi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle L.","family":"Scalley-Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric J.","family":"Alm","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Baker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1006\/jmbi.2000.3816_BIB1","doi-asserted-by":"crossref","first-page":"8466","DOI":"10.1021\/ja00098a005","article-title":"Sequence-corrected 15N \u201crandom coil\u201d chemical shifts","volume":"116","author":"Braun","year":"1994","journal-title":"J. Am. Chem. Soc."},{"key":"10.1006\/jmbi.2000.3816_BIB2","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1007\/BF00197809","article-title":"NMRPipe","volume":"6","author":"Delaglio","year":"1995","journal-title":"J. Biomol. NMR"},{"key":"10.1006\/jmbi.2000.3816_BIB3","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1038\/nsb0298-148","article-title":"Structural and dynamic characterization of partially folded states of apomyoglobin and implications for protein folding","volume":"5","author":"Eliezer","year":"1998","journal-title":"Nature Struct. Biol."},{"key":"10.1006\/jmbi.2000.3816_BIB4","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1107\/S0108767391001071","article-title":"Accurate bond and angle parameters for X-ray protein-structure refinement","volume":"47","author":"Engh","year":"1991","journal-title":"Acta Crystallog. sect. A"},{"key":"10.1006\/jmbi.2000.3816_BIB5","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1006\/jmbi.1998.1702","article-title":"Characterization of urea-denatured states of an immunoglobulin superfamily domain by heteronuclear NMR","volume":"278","author":"Fong","year":"1998","journal-title":"J. Mol. Biol."},{"key":"10.1006\/jmbi.2000.3816_BIB6","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1006\/jmbi.1997.0954","article-title":"Characterization of long-range structure in the denatured state of staphylococcal nuclease. I. Paramagnetic relaxation enhancement by nitroxide spin labels","volume":"268","author":"Gillespie","year":"1997","journal-title":"J. Mol. Biol."},{"key":"10.1006\/jmbi.2000.3816_BIB7","doi-asserted-by":"crossref","first-page":"6291","DOI":"10.1021\/ja00042a003","article-title":"Correlating backbone amide and side-chain resonances in larger proteins by multiple relayed triple resonance NMR","volume":"114","author":"Grzesiek","year":"1992","journal-title":"J. Am. Chem. Soc."},{"key":"10.1006\/jmbi.2000.3816_BIB8","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1007\/BF00178261","article-title":"Amino acid type determination in the sequential assignment procedure of uniformly 13C\/15N enriched proteins","volume":"3","author":"Grzesiek","year":"1993","journal-title":"J. Biomol. NMR"},{"key":"10.1006\/jmbi.2000.3816_BIB9","doi-asserted-by":"crossref","first-page":"1108","DOI":"10.1002\/pro.5560040609","article-title":"A phage display system for studying the sequence determinants of protein folding","volume":"4","author":"Gu","year":"1995","journal-title":"Protein Sci."},{"key":"10.1006\/jmbi.2000.3816_BIB10","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1006\/jmbi.1997.1374","article-title":"Contrasting roles for symmetrically disposed \u03b2-turns in the folding of a small protein","volume":"274","author":"Gu","year":"1997","journal-title":"J. Mol. Biol."},{"key":"10.1006\/jmbi.2000.3816_BIB11","doi-asserted-by":"crossref","first-page":"10663","DOI":"10.1021\/ja00052a088","article-title":"Pure absorpiton gradient enhanced heteronuclear single quantum correlation spectroscopy with improved sensitivity","volume":"114","author":"Kay","year":"1992","journal-title":"J. Am. Chem. Soc."},{"key":"10.1006\/jmbi.2000.3816_BIB12","doi-asserted-by":"crossref","DOI":"10.1006\/jmbi.2000.3701","article-title":"A breakdown of symmetry in the folding transition of protein L","author":"Kim","year":"2000","journal-title":"J. Mol. Biol."},{"key":"10.1006\/jmbi.2000.3816_BIB13","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1016\/0076-6879(89)77007-5","article-title":"Spin labeling of proteins","volume":"177","author":"Kosen","year":"1989","journal-title":"Methods Enzymol."},{"key":"10.1006\/jmbi.2000.3816_BIB14","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1006\/jmbi.1994.1173","article-title":"Structural characterization of the FK 506 binding protein unfolded in the urea and guanidine hydrochloride","volume":"236","author":"Logan","year":"1994","journal-title":"J. Mol. Biol."},{"key":"10.1006\/jmbi.2000.3816_BIB15","doi-asserted-by":"crossref","first-page":"7692","DOI":"10.1021\/bi960482k","article-title":"Motion of spin-labeled side chains in T4 lysozyme. Correlation with protein structure and dynamics","volume":"35","author":"Mchaourab","year":"1996","journal-title":"Biochemistry"},{"key":"10.1006\/jmbi.2000.3816_BIB16","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1006\/jmbi.1999.2769","article-title":"NOE data demonstrating a compact state for an SH3 domain under non-denaturing conditions","volume":"289","author":"Mok","year":"1998","journal-title":"J. Mol. Biol."},{"key":"10.1006\/jmbi.2000.3816_BIB17","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1126\/science.1523410","article-title":"NMR determination of residual structure in a urea-denatured protein, the 434-repressor","volume":"257","author":"Neri","year":"1992","journal-title":"Science"},{"key":"10.1006\/jmbi.2000.3816_BIB18","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1038\/9329","article-title":"Chain collapse can occur concomitantly with the rate-limiting step in protein folding","volume":"6","author":"Plaxco","year":"1999","journal-title":"Nature Struct. Biol."},{"key":"10.1006\/jmbi.2000.3816_BIB19","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1016\/S0969-2126(96)00133-5","article-title":"Use of deuterium labeling in the NMR","volume":"4","author":"Sattler","year":"1996","journal-title":"Structure"},{"key":"10.1006\/jmbi.2000.3816_BIB20","doi-asserted-by":"crossref","first-page":"15297","DOI":"10.1021\/bi991136g","article-title":"Structural transitions in the protein L denatured state ensemble","volume":"38","author":"Scalley","year":"1999","journal-title":"Biochemistry"},{"key":"10.1006\/jmbi.2000.3816_BIB21","doi-asserted-by":"crossref","first-page":"3373","DOI":"10.1021\/bi9625758","article-title":"Kinetics of folding of the IgG binding domain of peptosptreptococcal protein L","volume":"36","author":"Scalley","year":"1997","journal-title":"Biochemistry"},{"key":"10.1006\/jmbi.2000.3816_BIB22","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1096\/fasebj.10.1.8566543","article-title":"The denatured state (the other half of the folding equation) and its role in protein stability","volume":"10","author":"Shortle","year":"1996","journal-title":"FASEB J."},{"key":"10.1006\/jmbi.2000.3816_BIB23","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/S0959-440X(96)80091-1","article-title":"Structural analysis of non-native states of proteins by NMR methods","volume":"6","author":"Shortle","year":"1996","journal-title":"Curr. Opin. Struct. Biol."},{"key":"10.1006\/jmbi.2000.3816_BIB24","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1006\/jmbi.1997.0959","article-title":"Assembly of protein tertiary structures from fragments with similar local sequences using simulated annealing and Bayesian scoring functions","volume":"268","author":"Simons","year":"1997","journal-title":"J. Mol. Biol."},{"key":"10.1006\/jmbi.2000.3816_BIB25","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1063\/1.1742867","article-title":"Nuclear magnetic interactions in the HF molecule","volume":"25","author":"Solomon","year":"1956","journal-title":"J. Chem. Phys."},{"key":"10.1006\/jmbi.2000.3816_BIB26","doi-asserted-by":"crossref","first-page":"5490","DOI":"10.1021\/ja00014a071","article-title":"Empirical correlation between protein backbone conformation and Ca and Cb 13C nuclear magnetic resonance chemical shifts","volume":"113","author":"Spera","year":"1991","journal-title":"J. Am. Chem. Soc."},{"key":"10.1006\/jmbi.2000.3816_BIB27","doi-asserted-by":"crossref","first-page":"14011","DOI":"10.1021\/bi00251a008","article-title":"Three-dimensional solution structure of an immunoglobulin light chain-binding domain of protein L. Comparison with the IgG-binding domains of protein G","volume":"33","author":"Wikstrom","year":"1994","journal-title":"Biochemistry"},{"key":"10.1006\/jmbi.2000.3816_BIB28","first-page":"171","article-title":"The 13C chemical shift index","volume":"4","author":"Wishart","year":"1994","journal-title":"J. Biomol. NMR"},{"key":"10.1006\/jmbi.2000.3816_BIB29","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1006\/jmrb.1993.1033","article-title":"HNCACB, a high-sensitivity 3D NMR experiment to correlate amide-proton and nitrogen resonances with the alpha- and beta-carbon resonances in proteins","volume":"101","author":"Wittekind","year":"1993","journal-title":"J. Magn. Reson."},{"key":"10.1006\/jmbi.2000.3816_BIB30","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/S0014-5793(97)01474-9","article-title":"Chemical shift dispersion and secondary structure prediction in unfolded and partly-folded proteins","volume":"419","author":"Yao","year":"1997","journal-title":"FEBS Letters"},{"key":"10.1006\/jmbi.2000.3816_BIB31","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1002\/pro.5560050608","article-title":"Direct evidence for a two-state protein unfolding transition from hydrogen-deuterium exchange mass spectrometry and NMR","volume":"5","author":"Yi","year":"1996","journal-title":"Protein Sci."},{"key":"10.1006\/jmbi.2000.3816_BIB32","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/S1359-0278(97)00038-2","article-title":"Characterization of the free energy spectrum of peptostreptococcal protein L","volume":"2","author":"Yi","year":"1997","journal-title":"Fold. Des."},{"key":"10.1006\/jmbi.2000.3816_BIB33","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1023\/A:1018658305040","article-title":"Triple-resonance NOESY-based experiments with improved spectral resolution","volume":"9","author":"Zhang","year":"1997","journal-title":"J. Biol. NMR"},{"key":"10.1006\/jmbi.2000.3816_BIB34","first-page":"192","article-title":"Two-dimensional linear prediction for signals truncated in both dimensions","volume":"98","author":"Zhu","year":"1992","journal-title":"J. Magn. Reson."}],"container-title":["Journal of Molecular Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022283600938166?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022283600938166?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,12,16]],"date-time":"2019-12-16T14:31:50Z","timestamp":1576506710000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022283600938166"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,6]]},"references-count":34,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2000,6]]}},"alternative-id":["S0022283600938166"],"URL":"https:\/\/doi.org\/10.1006\/jmbi.2000.3816","relation":{},"ISSN":["0022-2836"],"issn-type":[{"value":"0022-2836","type":"print"}],"subject":[],"published":{"date-parts":[[2000,6]]}}}