{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T05:38:40Z","timestamp":1791092320571,"version":"4.1.0"},"reference-count":33,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2000,7,1]],"date-time":"2000-07-01T00:00:00Z","timestamp":962409600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Molecular and Cellular Cardiology"],"published-print":{"date-parts":[[2000,7]]},"DOI":"10.1006\/jmcc.2000.1159","type":"journal-article","created":{"date-parts":[[2002,9,18]],"date-time":"2002-09-18T18:06:17Z","timestamp":1032372377000},"page":"1249-1263","source":"Crossref","is-referenced-by-count":16,"title":["Different Regulation of Cardiac and Renal Corticosteroid Receptors in Aldosterone-salt Treated Rats: Effect of Hypertension and Glucocorticoids"],"prefix":"10.1016","volume":"32","author":[{"given":"Jean-S\u00e9bastien","family":"Silvestre","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9rie","family":"Robert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brigitte","family":"Escoubet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Heymes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdeslam","family":"Oub\u00e9na\u0131\u0308ssa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C\u00e9line","family":"Desopper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"Swynghedauw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claude","family":"Delcayre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1006\/jmcc.2000.1159_RF1","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/S0008-6363(99)00088-7","article-title":"Aldosterone and the heart: towards a physiological function?","volume":"43","author":"Delcayre","year":"1999","journal-title":"Cardiovasc Res"},{"key":"10.1006\/jmcc.2000.1159_RF2","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1006\/jmcc.1999.0963","article-title":"Extra-adrenal mineralocorticoids and cardiovascular tissue","volume":"31","author":"Slight","year":"1999","journal-title":"J Mol Cell Cardiol"},{"key":"10.1006\/jmcc.2000.1159_RF3","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1161\/01.CIR.95.6.1471","article-title":"Remodeling of the left ventricle in primary aldosteronism due to Conn's adenoma","volume":"95","author":"Rossi","year":"1997","journal-title":"Circulation"},{"key":"10.1006\/jmcc.2000.1159_RF4","doi-asserted-by":"crossref","first-page":"1730","DOI":"10.1161\/01.CIR.82.5.1730","article-title":"Hormones regulating cardiovascular function in patients with severe congestive heart failure and their relation to mortality, CONSENSUS trial study group","volume":"82","author":"Swedberg","year":"1990","journal-title":"Circulation"},{"key":"10.1006\/jmcc.2000.1159_RF5","doi-asserted-by":"crossref","first-page":"2694","DOI":"10.1161\/01.CIR.99.20.2694","article-title":"Activation of cardiac aldosterone production in rat myocardial infarction; Effect of Angiotensin II receptor blockade and role in cardiac fibrosis","volume":"99","author":"Silvestre","year":"1999","journal-title":"Circulation"},{"key":"10.1006\/jmcc.2000.1159_RF6","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1161\/01.RES.71.3.503","article-title":"Histochemical and biochemical evidence for a cardiovascular mineralocorticoid receptor","volume":"71","author":"Lomb\u00e8s","year":"1992","journal-title":"Circ Res"},{"key":"10.1006\/jmcc.2000.1159_RF7","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1006\/jmcc.1993.1066","article-title":"Anti-aldosterone treatment and the prevention of myocardial fibrosis in primary and secondary hyperaldosteronism","volume":"25","author":"Brilla","year":"1993","journal-title":"J Mol Cell Cardiol"},{"key":"10.1006\/jmcc.2000.1159_RF8","first-page":"404","article-title":"Angiotensin II and aldosterone receptor binding in rat heart and kidney: response to chronic angiotensin II or aldosterone administration","volume":"122","author":"Sun","year":"1993","journal-title":"J Lab Clin Med"},{"key":"10.1006\/jmcc.2000.1159_RF9","doi-asserted-by":"crossref","first-page":"C1343","DOI":"10.1152\/ajpcell.1996.270.5.C1343","article-title":"Corticosteroid receptor mRNA expression is unaffected by corticosteroids in rat kidney, heart, and colon","volume":"270","author":"Escoubet","year":"1996","journal-title":"Am J Physiol"},{"key":"10.1006\/jmcc.2000.1159_RF10","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/S0022-2828(86)80415-1","article-title":"Sex differences in the distribution and regulation of glucocorticoid receptors in cardiac tissues of rats","volume":"18","author":"Turner","year":"1986","journal-title":"J Mol Cell Cardiol"},{"key":"10.1006\/jmcc.2000.1159_RF11","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1126\/science.3037703","article-title":"Cloning of human mineralocorticoid receptor complementary DNA: structural and functional kinship with the glucocorticoid receptor","volume":"237","author":"Arriza","year":"1987","journal-title":"Science"},{"key":"10.1006\/jmcc.2000.1159_RF12","doi-asserted-by":"crossref","first-page":"6731","DOI":"10.1073\/pnas.89.15.6731","article-title":"At least three promoters direct expression of the mouse glucocorticoid receptor gene","volume":"89","author":"Strahle","year":"1992","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1006\/jmcc.2000.1159_RF13","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1146\/annurev.med.48.1.231","article-title":"Glucocorticoid and mineralocorticoid receptors: biology and clinical relevance","volume":"48","author":"Funder","year":"1997","journal-title":"Annu Rev Med"},{"key":"10.1006\/jmcc.2000.1159_RF14","doi-asserted-by":"crossref","first-page":"1810","DOI":"10.1210\/endo.139.4.5896","article-title":"Regulation of glucocorticoid receptor and mineralocorticoid receptor messenger ribonucleic acids by selective agonists in the rat hippocampus","volume":"139","author":"Chao","year":"1998","journal-title":"Endocrinology"},{"key":"10.1006\/jmcc.2000.1159_RF15","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/S0021-9258(19)70109-4","article-title":"Effect of adrenalectomy and aldosterone on the modulation of mineralocorticoid receptors in rat kidney","volume":"256","author":"Claire","year":"1981","journal-title":"J Biol Chem"},{"key":"10.1006\/jmcc.2000.1159_RF16","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1210\/endo.134.3.8119155","article-title":"In contrast to glucocorticoid receptors, mineralocorticoid receptors are not auto\u00cdregulated in rat distal colon epithelia","volume":"134","author":"Meyer","year":"1994","journal-title":"Endocrinology"},{"key":"10.1006\/jmcc.2000.1159_RF17","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/0006-8993(94)90174-0","article-title":"Aldosterone modulates glucocorticoid receptor binding in hippocampal cell cultures via the mineralocorticoid receptor","volume":"636","author":"0\u00bbDonnell","year":"1994","journal-title":"Brain Res"},{"key":"10.1006\/jmcc.2000.1159_RF18","doi-asserted-by":"crossref","first-page":"C1","DOI":"10.1016\/0303-7207(92)90187-B","article-title":"The down side of glucocorticoid receptor regulation","volume":"83","author":"Burnstein","year":"1992","journal-title":"Mol Cell Endocrinol"},{"key":"10.1006\/jmcc.2000.1159_RF19","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/0960-0760(91)90202-G","article-title":"The mechanism for glucocorticoid-resistance in a rat hepatoma cell variant that contains functional glucocorticoid receptor","volume":"40","author":"Okret","year":"1991","journal-title":"J Steroid Biochem Mol Biol"},{"key":"10.1006\/jmcc.2000.1159_RF20","doi-asserted-by":"crossref","first-page":"10441","DOI":"10.1016\/S0021-9258(18)60980-9","article-title":"Tissue-specific regulation of glucocorticoid receptor mRNA by dexamethasone","volume":"262","author":"Kalinyak","year":"1987","journal-title":"J Biol Chem"},{"key":"10.1006\/jmcc.2000.1159_RF21","doi-asserted-by":"crossref","first-page":"2344","DOI":"10.1210\/endo.133.5.8404687","article-title":"5\u2032 heterogeneity of the mineralocorticoid receptor messenger ribonucleic acid: differential expression and regulation of splices variants within rat hippocampus","volume":"133","author":"Kwak","year":"1993","journal-title":"Endocrinology"},{"key":"10.1006\/jmcc.2000.1159_RF22","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal Biochem"},{"key":"10.1006\/jmcc.2000.1159_RF23","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1161\/01.HYP.24.1.30","article-title":"Increased cardiac types I and III collagen mRNAs in aldosterone-salt hypertension","volume":"24","author":"Robert","year":"1994","journal-title":"Hypertension"},{"key":"10.1006\/jmcc.2000.1159_RF24","first-page":"38","article-title":"Hyperaldosteronism accompanied by normal or elevated mineral\u00cdocorticosteroid pathway steroid: a marker of adrenal carcinoma","volume":"76","author":"Aupetit-Faisant","year":"1993","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1006\/jmcc.2000.1159_RF25","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1161\/01.HYP.26.6.971","article-title":"Biological determinants of aldosterone-induced cardiac fibrosis in rats","volume":"26","author":"Robert","year":"1995","journal-title":"Hypertension"},{"key":"10.1006\/jmcc.2000.1159_RF26","first-page":"H979","article-title":"Atrial natriuretic factor gene expression in rat ventricle during experimental hypertension","volume":"257","author":"Mercadier","year":"1989","journal-title":"Am J Physiol"},{"key":"10.1006\/jmcc.2000.1159_RF27","doi-asserted-by":"crossref","first-page":"5899","DOI":"10.1073\/pnas.83.16.5899","article-title":"Down-regulation of glucocorticoid receptor mRNA by glucocorticoid hormones and recognition by the receptor of a specific binding sequence within a receptor cDNA clone","volume":"83","author":"Okret","year":"1986","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1006\/jmcc.2000.1159_RF28","doi-asserted-by":"crossref","first-page":"1674","DOI":"10.1210\/mend-3-10-1674","article-title":"Type I and II corticosteroid receptor gene expression in the rat: effect of adrenalectomy and dexamethasone administration","volume":"3","author":"Reul","year":"1989","journal-title":"Mol Endocrinol"},{"key":"10.1006\/jmcc.2000.1159_RF29","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/S0021-9258(18)89748-4","article-title":"Triamcinolone acetonide regulates glucocorticoid receptor levels by decreasing the half-life of the activated nuclear receptor form","volume":"260","author":"McIntyre","year":"1985","journal-title":"J Biol Chem"},{"key":"10.1006\/jmcc.2000.1159_RF30","first-page":"1549","article-title":"Characterization of the human mineralocorticoid receptor gene 5\u2032-regulatory region: evidence for differential hormonal regulation of two alternative promoters via nonclassical mechanisms","volume":"10","author":"Zennaro","year":"1996","journal-title":"Mol Endocrinol"},{"key":"10.1006\/jmcc.2000.1159_RF31","first-page":"1764","article-title":"Intragenic sequences of the human glucocorticoid receptor complementary DNA mediate hormone-inducible receptor messenger RNA down-regulation through multiple mechanisms","volume":"8","author":"Burnstein","year":"1994","journal-title":"Mol Endocrinol"},{"key":"10.1006\/jmcc.2000.1159_RF32","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1161\/01.HYP.33.4.981","article-title":"Angiotensin AT1 receptor subtype as a cardiac target of aldosterone; role in aldosterone-salt induced fibrosis","volume":"33","author":"Robert","year":"1999","journal-title":"Hypertension"},{"key":"10.1006\/jmcc.2000.1159_RF33","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1056\/NEJM199909023411001","article-title":"Randomized ALdactone Evaluation Study Investigators. The effect of spironolactone on morbidity and mortality in patients with severe heart failure","volume":"341","author":"Pitt","year":"1999","journal-title":"N Engl J Med"}],"container-title":["Journal of Molecular and Cellular Cardiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022282800911593?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022282800911593?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,5,3]],"date-time":"2021-05-03T01:58:26Z","timestamp":1620007106000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022282800911593"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,7]]},"references-count":33,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2000,7]]}},"alternative-id":["S0022282800911593"],"URL":"https:\/\/doi.org\/10.1006\/jmcc.2000.1159","relation":{},"ISSN":["0022-2828"],"issn-type":[{"value":"0022-2828","type":"print"}],"subject":[],"published":{"date-parts":[[2000,7]]}}}