{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T10:31:07Z","timestamp":1778841067138,"version":"3.51.4"},"reference-count":46,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[1999,8,1]],"date-time":"1999-08-01T00:00:00Z","timestamp":933465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[1999,8,1]],"date-time":"1999-08-01T00:00:00Z","timestamp":933465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000069","name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","doi-asserted-by":"publisher","award":["AR44737"],"award-info":[{"award-number":["AR44737"]}],"id":[{"id":"10.13039\/100000069","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Structural Biology"],"published-print":{"date-parts":[[1999,8]]},"DOI":"10.1006\/jsbi.1999.4127","type":"journal-article","created":{"date-parts":[[2002,9,18]],"date-time":"2002-09-18T14:57:36Z","timestamp":1032361056000},"page":"22-34","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["Determination of Fluorescent Probe Orientations on Biomolecules by Conformational Searching: Algorithm Testing and Applications to the Atomic Model of Myosin"],"prefix":"10.1016","volume":"127","author":[{"given":"Douglas D.","family":"Root","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin","family":"Shangguan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael A.","family":"McAllister","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1006\/jsbi.1999.4127_RF1","doi-asserted-by":"crossref","first-page":"8457","DOI":"10.1021\/bi00084a010","article-title":"Crystal structure of a fluorescent derivative of RNase A","volume":"32","author":"Baudet-Nessler","year":"1993","journal-title":"Biochemistry"},{"key":"10.1006\/jsbi.1999.4127_RF2","series-title":"Biophysical Chemistry: II Techniques for the Study of Biological Structure and Function","author":"Cantor","year":"1980"},{"key":"10.1006\/jsbi.1999.4127_RF3","doi-asserted-by":"crossref","first-page":"4412","DOI":"10.1063\/1.1669892","article-title":"Spectral intensities of the trivalent lanthanides and actinides in solution. II. Pm3+, Sm3+, Eu3+, Gd3+, Tb3+, Dy3+, and Ho3+","volume":"49","author":"Carnall","year":"1968","journal-title":"J. Chem. Phys."},{"key":"10.1006\/jsbi.1999.4127_RF4","doi-asserted-by":"crossref","first-page":"4379","DOI":"10.1021\/ja00194a035","article-title":"An internal coordinate Monte Carlo method for searching conformational space","volume":"111","author":"Chang","year":"1989","journal-title":"J. Am. Chem. Soc."},{"key":"10.1006\/jsbi.1999.4127_RF5","doi-asserted-by":"crossref","first-page":"5775","DOI":"10.1016\/S0021-9258(20)81961-9","article-title":"Fluorescence energy transfer studies on the proximity of the two essential thiols of myosin subfragment-1","volume":"258","author":"Cheung","year":"1983","journal-title":"J. Biol. Chem."},{"key":"10.1006\/jsbi.1999.4127_RF6","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/0167-4838(85)90173-6","article-title":"An investigation of the SH1-SH2 and SH1-ATPase distances in myosin subfragment-1 by resonance energy transfer using nanosecond fluorimetry","volume":"832","author":"Cheung","year":"1985","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1006\/jsbi.1999.4127_RF7","doi-asserted-by":"crossref","first-page":"5094","DOI":"10.1063\/1.1678194","article-title":"Theory of fluorescence depolarization by anisotropic rotational diffusion","volume":"57","author":"Chuang","year":"1972","journal-title":"J. Chem. Phys."},{"key":"10.1006\/jsbi.1999.4127_RF8","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/0076-6879(92)11020-J","article-title":"Fluorescence resonance energy transfer and nucleic acids","volume":"211","author":"Clegg","year":"1992","journal-title":"Methods Enzymol."},{"key":"10.1006\/jsbi.1999.4127_RF9","doi-asserted-by":"crossref","first-page":"2994","DOI":"10.1073\/pnas.90.7.2994","article-title":"Observing the helical geometry of double-stranded DNA in solution by fluorescence resonance energy transfer","volume":"90","author":"Clegg","year":"1993","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1006\/jsbi.1999.4127_RF10","series-title":"Proteins: Structures and Molecular Properties","author":"Creighton","year":"1993"},{"key":"10.1006\/jsbi.1999.4127_RF11","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0006-3495(79)85243-1","article-title":"The orientational freedom of molecular probes. The orientation factor in intramolecular energy transfer","volume":"26","author":"Dale","year":"1979","journal-title":"Biophys. J."},{"key":"10.1006\/jsbi.1999.4127_RF12","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1016\/0022-2836(81)90357-0","article-title":"Structure of a B-DNA dodecamer. II. Influence of base sequence on helix structure","volume":"149","author":"Dickerson","year":"1981","journal-title":"J. Mol. Biol."},{"key":"10.1006\/jsbi.1999.4127_RF13","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1038\/nsb0197-10","article-title":"From Levinthal to pathways to funnels","volume":"4","author":"Dill","year":"1997","journal-title":"Nat. Struct. Biol."},{"key":"10.1006\/jsbi.1999.4127_RF14","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1006\/jsbi.1995.1042","article-title":"Fluorescence resonance energy transfer spectroscopy is a reliable \u201cruler\u201d for measuring structural changes in proteins. Dispelling the problem of the unknown orientation factor","volume":"115","author":"dos Remedios","year":"1995","journal-title":"J. Struct. Biol."},{"key":"10.1006\/jsbi.1999.4127_RF15","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1002\/jcc.540120512","article-title":"Can the Lennard-Jones 6-12 function replace the 10-12 form in molecular mechanics calculations","volume":"12","author":"Ferguson","year":"1991","journal-title":"J. Comp. Chem."},{"key":"10.1006\/jsbi.1999.4127_RF16","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1002\/andp.19484370105","article-title":"Zwischenmolekulare Energiwanderung und Fluoreszence [Intermolecular energy migration and fluorescence]","volume":"2","author":"F\u00f6rster","year":"1948","journal-title":"Ann. Phys."},{"key":"10.1006\/jsbi.1999.4127_RF17","doi-asserted-by":"crossref","first-page":"11619","DOI":"10.1021\/bi9712596","article-title":"X-ray structures of the MgADP, MgATPgammaS, and MgAMPPNP complexes of the Dictyostelium discoideum myosin motor domain","volume":"36","author":"Gulick","year":"1997","journal-title":"Biochemistry"},{"key":"10.1006\/jsbi.1999.4127_RF18","series-title":"CRC Handbook of Chemistry and Physics","first-page":"4","author":"Gschneider","year":"1997"},{"key":"10.1006\/jsbi.1999.4127_RF19","doi-asserted-by":"crossref","first-page":"6957","DOI":"10.1021\/ja00726a038","article-title":"The flow birefringence of persistence length deoxyribonucleic acid: Hydrodynamic properties, optical anisotropy, and hydration shell anisotropy","volume":"92","author":"Harrington","year":"1970","journal-title":"J. Am. Chem. Soc."},{"key":"10.1006\/jsbi.1999.4127_RF20","doi-asserted-by":"crossref","first-page":"4764","DOI":"10.1073\/pnas.72.12.4764","article-title":"Energy transfer between terbium (III) and cobalt (II) in thermolysin: A new class of metal\u2013metal distance probes","volume":"72","author":"Horrocks","year":"1975","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1006\/jsbi.1999.4127_RF21","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1038\/375688a0","article-title":"Tilting of the light-chain region of myosin during step length changes and active force generation in skeletal muscle","volume":"375","author":"Irving","year":"1995","journal-title":"Nature"},{"key":"10.1006\/jsbi.1999.4127_RF22","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1006\/jmbi.1996.0188","article-title":"Determination of DNA helical handedness by fluorescence resonance energy transfer","volume":"257","author":"Jares-Erijman","year":"1996","journal-title":"J. Mol. Biol."},{"key":"10.1006\/jsbi.1999.4127_RF23","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1007\/BF00542558","article-title":"Quenching by acrylamide and temperature of a fluorescent probe attached to the active site of ribonuclease","volume":"13","author":"Jullien","year":"1986","journal-title":"Eur. Biophys. J."},{"key":"10.1006\/jsbi.1999.4127_RF24","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1083\/jcb.134.4.895","article-title":"Glycine 699 is pivotal for the motor activity of skeletal muscle myosin","volume":"134","author":"Kinose","year":"1996","journal-title":"J. Cell Biol."},{"key":"10.1006\/jsbi.1999.4127_RF25","doi-asserted-by":"crossref","first-page":"11261","DOI":"10.1021\/bi9707887","article-title":"Design and characterization of a multisite fluorescence energy-transfer system for protein folding studies: A steady-state and time-resolved study of yeast phosphoglycerate kinase","volume":"36","author":"Lillo","year":"1997","journal-title":"Biochemistry"},{"key":"10.1006\/jsbi.1999.4127_RF26","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1002\/bip.360350213","article-title":"Fluorescence energy transfer in one dimension: Frequency-domain fluorescence study of DNA\u2013fluorophore complexes","volume":"35","author":"Maliwal","year":"1994","journal-title":"Biopolymers"},{"key":"10.1006\/jsbi.1999.4127_RF27","doi-asserted-by":"crossref","first-page":"R1","DOI":"10.1016\/S1359-0278(97)00001-1","article-title":"Folding studies on ribonuclease A, a model protein","volume":"2","author":"Neira","year":"1997","journal-title":"Folding Design"},{"key":"10.1006\/jsbi.1999.4127_RF28","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1098\/rspa.1927.0035","article-title":"The theoretical prediction of the physical properties of many-electron atoms and ions. Mole refraction, diamagnetic susceptibility, and extension in space","volume":"114","author":"Pauling","year":"1927","journal-title":"Proc. R. Soc. London A"},{"key":"10.1006\/jsbi.1999.4127_RF29","doi-asserted-by":"crossref","first-page":"3864","DOI":"10.1073\/pnas.92.9.3864","article-title":"Structural interpretation of the mutations in the beta-cardiac myosin that have been implicated in familial hypertrophic cardiomyopathy","volume":"92","author":"Rayment","year":"1995","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1006\/jsbi.1999.4127_RF30","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1126\/science.8316857","article-title":"Three-dimensional structure of myosin subfragment-1: A molecular motor","volume":"261","author":"Rayment","year":"1993","journal-title":"Science"},{"key":"10.1006\/jsbi.1999.4127_RF31","doi-asserted-by":"crossref","first-page":"5685","DOI":"10.1073\/pnas.94.11.5685","article-title":"In situ molecular association of dystrophin with actin revealed by sensitized emission immuno-resonance energy transfer","volume":"94","author":"Root","year":"1997","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1006\/jsbi.1999.4127_RF32","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1016\/S0006-3495(92)81646-6","article-title":"Cooperativity of thiol-modified myosin filaments: ATPase and motility assays of myosin function","volume":"63","author":"Root","year":"1992","journal-title":"Biophys. J."},{"key":"10.1006\/jsbi.1999.4127_RF33","series-title":"Biochemical Fluorescence: Concepts I","first-page":"285","article-title":"The measurement of intramolecular distances by energy transfer","author":"Schiller","year":"1975"},{"key":"10.1006\/jsbi.1999.4127_RF34","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1021\/ja00706a043","article-title":"Emission properties of NADH. Studies of fluorescence lifetimes and quantum efficiencies of NADH, AcPyADH, and simplified synthetic models","volume":"92","author":"Scott","year":"1970","journal-title":"J. Am. Chem. Soc."},{"key":"10.1006\/jsbi.1999.4127_RF35","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1016\/0076-6879(95)46015-2","article-title":"Fluorescence resonance energy transfer","volume":"246","author":"Selvin","year":"1995","journal-title":"Methods Enzymol."},{"key":"10.1006\/jsbi.1999.4127_RF36","doi-asserted-by":"crossref","first-page":"10024","DOI":"10.1073\/pnas.91.21.10024","article-title":"Luminescence energy transfer using a terbium chelate: Improvements on fluorescence energy transfer","volume":"91","author":"Selvin","year":"1994","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1006\/jsbi.1999.4127_RF37","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1021\/ic950840s","article-title":"Crystal structure and spectroscopic characterization of a luminescent europium chelate","volume":"35","author":"Selvin","year":"1996","journal-title":"Inorg. Chem."},{"key":"10.1006\/jsbi.1999.4127_RF38","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1063\/1.430264","article-title":"Energy gap law in the solvent isotope effect on radiationless transitions of rare earth ions","volume":"62","author":"Stein","year":"1975","journal-title":"J. Chem. Phys."},{"key":"10.1006\/jsbi.1999.4127_RF39","doi-asserted-by":"crossref","first-page":"6127","DOI":"10.1021\/ja00172a038","article-title":"Semianalytical treatment of solvation for molecular mechanism and dynamics","volume":"112","author":"Still","year":"1990","journal-title":"J. Am. Chem. Soc."},{"key":"10.1006\/jsbi.1999.4127_RF40","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1073\/pnas.58.2.719","article-title":"Energy transfer: A spectroscopic ruler","volume":"58","author":"Stryer","year":"1967","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1006\/jsbi.1999.4127_RF41","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1002\/bip.1969.360080505","article-title":"Time-dependent fluorescence depolarization and brownian rotational diffusion coefficients of macromolecules","volume":"8","author":"Tao","year":"1969","journal-title":"Biopolymers"},{"key":"10.1006\/jsbi.1999.4127_RF42","doi-asserted-by":"crossref","first-page":"3567","DOI":"10.1021\/ic00094a021","article-title":"Synthesis, stability, and structure of gadolinium(III) and yttrium(III) macrocyclic poly(amino carboxylates)","volume":"33","author":"Tweedle","year":"1994","journal-title":"Inorg. Chem."},{"key":"10.1006\/jsbi.1999.4127_RF43","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/BF00185121","article-title":"The orientation of transition moments of dye molecules used in fluorescence studies of muscle systems","volume":"21","author":"van der Heide","year":"1992","journal-title":"Eur. Biophys. J."},{"key":"10.1006\/jsbi.1999.4127_RF44","doi-asserted-by":"crossref","first-page":"1711","DOI":"10.1021\/bi00549a030","article-title":"Reaction of 5,5\u2032-dithiobis(2-nitrobenzoic acid) with myosin one: Evidence for formation of a single protein disulfide with trapping of metal nucleotide at the active site","volume":"19","author":"Wells","year":"1980","journal-title":"Biochemistry"},{"key":"10.1006\/jsbi.1999.4127_RF45","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1006\/jsbi.1998.4023","article-title":"Domain motion between the regulatory light chain and the nucleotide site in skeletal myosin","volume":"123","author":"Xu","year":"1998","journal-title":"J. Struct. Biol."},{"key":"10.1006\/jsbi.1999.4127_RF46","doi-asserted-by":"crossref","first-page":"2313","DOI":"10.1016\/S0006-3495(97)78263-8","article-title":"A 5-nanosecond molecular dynamics trajectory for B-DNA: Analysis of structure, motions, and solvation","volume":"73","author":"Young","year":"1997","journal-title":"Biophys. J."}],"container-title":["Journal of Structural Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1047847799941278?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1047847799941278?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T03:06:23Z","timestamp":1760929583000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1047847799941278"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,8]]},"references-count":46,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1999,8]]}},"alternative-id":["S1047847799941278"],"URL":"https:\/\/doi.org\/10.1006\/jsbi.1999.4127","relation":{},"ISSN":["1047-8477"],"issn-type":[{"value":"1047-8477","type":"print"}],"subject":[],"published":{"date-parts":[[1999,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Determination of Fluorescent Probe Orientations on Biomolecules by Conformational Searching: Algorithm Testing and Applications to the Atomic Model of Myosin","name":"articletitle","label":"Article Title"},{"value":"Journal of Structural Biology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1006\/jsbi.1999.4127","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1999 Academic Press. All rights reserved.","name":"copyright","label":"Copyright"}]}}