{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T18:14:31Z","timestamp":1648577671412},"reference-count":23,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2001,5,1]],"date-time":"2001-05-01T00:00:00Z","timestamp":988675200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Surgical Research"],"published-print":{"date-parts":[[2001,5]]},"DOI":"10.1006\/jsre.2001.6130","type":"journal-article","created":{"date-parts":[[2002,9,18]],"date-time":"2002-09-18T18:57:36Z","timestamp":1032375456000},"page":"97-102","source":"Crossref","is-referenced-by-count":6,"title":["Clostridium difficile Toxins and Enterococcal Translocation in Vivo and in Vitro"],"prefix":"10.1006","volume":"97","author":[{"given":"B.A","family":"Feltis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.M","family":"Garni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.L","family":"Wells","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1006\/jsre.2001.6130_RF1","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1001\/archsurg.134.11.1235","article-title":"Clostridium difficile toxins may augment bacterial penetration of intestinal epithelium","volume":"134","author":"Feltis","year":"1999","journal-title":"Arch. Surg."},{"key":"10.1006\/jsre.2001.6130_RF2","doi-asserted-by":"crossref","unstructured":"Feltis, B. A, Wiesner, S. M, Kim, A. S, Erlandsen, S. L, Lyerly, D. L, Wilkins, T. D, and, Wells, C. L. Clostridium difficile toxins A and B can alter epithelial permeability and promote bacterial paracellular migration through HT-29 enterocytes, Shock, 2000, in press.","DOI":"10.1097\/00024382-200014060-00010"},{"key":"10.1006\/jsre.2001.6130_RF3","first-page":"12","article-title":"Clostridium difficile infection pathophysiology and diagnosis","volume":"8","author":"Bartlett","year":"1997","journal-title":"Semin. Gastrointest. Dis."},{"key":"10.1006\/jsre.2001.6130_RF4","doi-asserted-by":"crossref","first-page":"2004","DOI":"10.1172\/JCI117885","article-title":"Clostridium difficile toxin B is more potent than Toxin A in damaging human colonic epithelium in vitro","volume":"95","author":"Riegler","year":"1995","journal-title":"J. Clin. Invest."},{"key":"10.1006\/jsre.2001.6130_RF5","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1053\/gast.1996.v110.pm8613048","article-title":"Bacteroides fragilis enterotoxin modulates epithelial permeability and bacterial internalization by HT-29 enterocytes","volume":"110","author":"Wells","year":"1996","journal-title":"Gastroenterology"},{"key":"10.1006\/jsre.2001.6130_RF6","doi-asserted-by":"crossref","first-page":"5125","DOI":"10.1128\/IAI.66.11.5125-5131.1998","article-title":"Activation of Rho GTPases by Escherichia coli cytotoxic necrotizing factor 1 increases intestinal permeability in Caco-2 cells","volume":"66","author":"Gerhard","year":"1998","journal-title":"Infect. Immun."},{"key":"10.1006\/jsre.2001.6130_RF7","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1053\/gast.1997.v112.pm9041245","article-title":"The enterotoxic effect of zonula occludens toxin on rabbit small intestine involves the paracellular pathway","volume":"112","author":"Fasano","year":"1997","journal-title":"Gastroenterology"},{"key":"10.1006\/jsre.2001.6130_RF8","unstructured":"Becton Dickinson and Company. Difco Manual, 11th ed., 1998."},{"key":"10.1006\/jsre.2001.6130_RF9","doi-asserted-by":"crossref","first-page":"1032","DOI":"10.1128\/IAI.35.3.1032-1040.1982","article-title":"Purification and characterization of toxins A and B of Clostridium difficile","volume":"35","author":"Sullivan","year":"1982","journal-title":"Infect. Immunity"},{"key":"10.1006\/jsre.2001.6130_RF10","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1111\/j.1574-6968.1986.tb01206.x","article-title":"Properties of toxins A and B of Clostridium difficile","volume":"33","author":"Lyerly","year":"1986","journal-title":"FEMS Microbiol. Lett."},{"key":"10.1006\/jsre.2001.6130_RF11","doi-asserted-by":"crossref","first-page":"2689","DOI":"10.1128\/IAI.55.11.2689-2694.1987","article-title":"Role of anaerobic flora in the translocation of aerobic and facultatively anaerobic intestinal bacteria","volume":"55","author":"Wells","year":"1987","journal-title":"Infect. Immun."},{"key":"10.1006\/jsre.2001.6130_RF12","series-title":"Color Atlas and Textbook of Diagnostic Microbiology","author":"Koneman","year":"1997"},{"key":"10.1006\/jsre.2001.6130_RF13","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1128\/AAC.36.7.1374","article-title":"Epithelial cells in culture as a model for the intestinal transport of antimicrobial agents","volume":"36","author":"Ranaldi","year":"1992","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1006\/jsre.2001.6130_RF14","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1001\/archsurg.1995.01430010055011","article-title":"The effect of endotoxin on intestinal mucosal permeability to bacteria in vitro","volume":"130","author":"Go","year":"1995","journal-title":"Arch. Surg."},{"key":"10.1006\/jsre.2001.6130_RF15","series-title":"Functional Epithelial Cells in Culture","first-page":"363","article-title":"Differentiation of intestinal epithelial cells in vitro","author":"Neutra","year":"1989"},{"key":"10.1006\/jsre.2001.6130_RF16","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1097\/00075198-200004000-00007","article-title":"Does microbial translocation play a role in critical illness?","volume":"6","author":"Feltis","year":"2000","journal-title":"Curr. Opin. Crit. Care"},{"key":"10.1006\/jsre.2001.6130_RF17","first-page":"21","article-title":"Risk factors for multiple organ system failure and death in critically injured patients","volume":"114","author":"Tran","year":"1993","journal-title":"Surgery"},{"key":"10.1006\/jsre.2001.6130_RF18","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1128\/CMR.3.1.46","article-title":"The life and times of the enterococcus","volume":"3","author":"Murray","year":"1990","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1006\/jsre.2001.6130_RF19","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1128\/CMR.6.4.428","article-title":"An overview of nosocomial infections, including the role of the microbiology laboratory","volume":"6","author":"Emori","year":"1993","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1006\/jsre.2001.6130_RF20","doi-asserted-by":"crossref","first-page":"943","DOI":"10.4065\/73.10.943","article-title":"Extraintestinal Clostridium difficile: 10 years' experience at a tertiary-care hospital","volume":"73","author":"Wolf","year":"1998","journal-title":"Mayo Clinic Proc."},{"key":"10.1006\/jsre.2001.6130_RF21","series-title":"Germfree Life and Gnotobiology","author":"Luckey","year":"1963"},{"key":"10.1006\/jsre.2001.6130_RF22","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1099\/00222615-24-1-53","article-title":"Clostridium difficile\u2014A spectrum of virulence and analysis of putative virulence determinants in the hamster model of antibiotic-associated colitis","volume":"24","author":"Borriello","year":"1987","journal-title":"J. Med. Microb"},{"key":"10.1006\/jsre.2001.6130_RF23","doi-asserted-by":"crossref","first-page":"2018","DOI":"10.1128\/IAI.66.5.2018-2025.1998","article-title":"Antibodies to recombinant Clostridium difficile toxins A and B are an effective treatment and prevent relapse of C. difficile-associated disease in a hamster model of infection","volume":"66","author":"Kink","year":"1998","journal-title":"Infect. Immun."}],"container-title":["Journal of Surgical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002248040196130X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S002248040196130X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,5,3]],"date-time":"2021-05-03T04:30:09Z","timestamp":1620016209000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S002248040196130X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,5]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2001,5]]}},"alternative-id":["S002248040196130X"],"URL":"https:\/\/doi.org\/10.1006\/jsre.2001.6130","relation":{},"ISSN":["0022-4804"],"issn-type":[{"value":"0022-4804","type":"print"}],"subject":[],"published":{"date-parts":[[2001,5]]}}}