{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T07:00:04Z","timestamp":1792652404973,"version":"4.5.0"},"reference-count":25,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2001,12,1]],"date-time":"2001-12-01T00:00:00Z","timestamp":1007164800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2001,12,1]],"date-time":"2001-12-01T00:00:00Z","timestamp":1007164800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","journalofsurgicalresearch.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Journal of Surgical Research"],"published-print":{"date-parts":[[2001,12]]},"DOI":"10.1006\/jsre.2001.6263","type":"journal-article","created":{"date-parts":[[2002,9,18]],"date-time":"2002-09-18T14:57:36Z","timestamp":1032361056000},"page":"176-182","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["A Long-Term Stable Normothermic Cardiopulmonary Bypass Model in Neonatal Swine"],"prefix":"10.1006","volume":"101","author":[{"given":"Carin","family":"Wittnich","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael P.","family":"Belanger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W.Jack","family":"Wallen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shona M.","family":"Torrance","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steve","family":"Juhasz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1006\/jsre.2001.6263_RF1","series-title":"Cardiopulmonary Bypass: Principles and Practice","first-page":"713","article-title":"Noncardiovascular applications of cardiovascular bypass","author":"Murray","year":"1993"},{"key":"10.1006\/jsre.2001.6263_RF2","first-page":"6","article-title":"Pediatric cardiopulmonary bypass and heart preservation","volume":"3","author":"Wittnich","year":"1991","journal-title":"Can. J. Pediatr."},{"key":"10.1006\/jsre.2001.6263_RF3","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1016\/S0003-4975(97)00905-3","article-title":"Detrimental effects of cardiopulmonary bypass in cyanotic infants: Preventing the reoxygenation injury","volume":"64","author":"Allen","year":"1997","journal-title":"Ann. Thorac. Surg."},{"key":"10.1006\/jsre.2001.6263_RF4","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1006\/jsre.1999.5602","article-title":"Cardiopulmonary bypass increases coronary IL-8 in diabetic patients without evidence of reperfusion injury","volume":"84","author":"Nawas","year":"1999","journal-title":"J. Surg. Res."},{"key":"10.1006\/jsre.2001.6263_RF5","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1016\/0003-4975(91)91267-Y","article-title":"Not all neonatal hearts are equally protected from ischemic damage during hypothermia","volume":"52","author":"Wittnich","year":"1991","journal-title":"Ann. Thorac. Surg."},{"key":"10.1006\/jsre.2001.6263_RF6","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/S0022-5223(99)70430-7","article-title":"Results of 102 cases of complete repair of congenital heart defects in patients weighing 700 to 2500 grams","volume":"117","author":"Reddy","year":"1999","journal-title":"J. Thorac. Cardiovasc. Surg."},{"key":"10.1006\/jsre.2001.6263_RF7","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1006\/jsre.1999.5702","article-title":"Cardiopulmonary bypass renders patients at risk for multiple organ failure via early neutrophil priming and late neutrophil disability","volume":"86","author":"Partrick","year":"1999","journal-title":"J. Surg. Res."},{"key":"10.1006\/jsre.2001.6263_RF8","series-title":"Cardiopulmonary Bypass: Principles and Practice","first-page":"603","article-title":"Cardiopulmonary bypass in infants and children","author":"Gates","year":"1993"},{"key":"10.1006\/jsre.2001.6263_RF9","first-page":"175","article-title":"Age-related differences in myocardial metabolism affects response to ischemia. Age in heart tolerance to ischemia","volume":"4","author":"Wittnich","year":"1992","journal-title":"Am. J. Cardiovasc. Pathol."},{"key":"10.1006\/jsre.2001.6263_RF10","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1006\/jmcc.1994.1080","article-title":"Does the severity of acute hypoxia influence neonatal myocardial metabolism and sensitivity to ischemia?","volume":"26","author":"Wittnich","year":"1994","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1006\/jsre.2001.6263_RF11","first-page":"317","article-title":"Comparison of mild and deep hypothermia: Do they provide similar protection in all neonatal hearts?","volume":"34","author":"Wittnich","year":"1991","journal-title":"Can. J. Surg."},{"key":"10.1006\/jsre.2001.6263_RF12","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/0003-4975(96)00331-1","article-title":"Influence of age on cerebral recovery after deep hypothermic circulatory arrest in piglets","volume":"62","author":"Nomura","year":"1996","journal-title":"Ann. Thorac. Surg."},{"key":"10.1006\/jsre.2001.6263_RF13","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1006\/jsre.1996.0218","article-title":"Myocardial glucose metabolism and ATP levels are decreased two days after global ischemia","volume":"63","author":"Baldwin","year":"1996","journal-title":"J. Surg. Res."},{"key":"10.1006\/jsre.2001.6263_RF14","first-page":"2809","article-title":"Controlling oxygen content during cardiopulmonary bypass to limit reperfusion\/reoxygenation injury","volume":"27","author":"Ihnken","year":"1995","journal-title":"Transplant. Proc."},{"key":"10.1006\/jsre.2001.6263_RF15","doi-asserted-by":"crossref","first-page":"2318","DOI":"10.1152\/jappl.1994.77.5.2318","article-title":"Blood lactate and acid-base balance in graded neonatal hypoxia: Evidence for oxygen-restricted metabolism","volume":"77","author":"Torrance","year":"1994","journal-title":"J. Appl. Physiol."},{"key":"10.1006\/jsre.2001.6263_RF16","series-title":"Cardiopulmonary Bypass: Principles and Practice","first-page":"155","article-title":"Myocardial protection during cardiac surgery","author":"Vinten-Johansen","year":"1993"},{"key":"10.1006\/jsre.2001.6263_RF17","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/S0952-8180(98)00085-3","article-title":"Temperature and duration of cardiopulmonary bypass influence transfusion requirements","volume":"10","author":"Ereth","year":"1998","journal-title":"J. Clin. Anesth."},{"key":"10.1006\/jsre.2001.6263_RF18","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/S0003-4975(99)00040-5","article-title":"A prospective, randomized study of cardiopulmonary bypass temperature and blood transfusion","volume":"76","author":"Stenrud","year":"1999","journal-title":"Ann. Thorac. Surg."},{"key":"10.1006\/jsre.2001.6263_RF19","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1161\/01.STR.31.3.707","article-title":"Longer duration of cardiopulmonary bypass is associated with greater numbers of cerebral microemboli","volume":"31","author":"Brown","year":"2000","journal-title":"Stroke"},{"key":"10.1006\/jsre.2001.6263_RF20","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1016\/S0003-4975(98)00113-1","article-title":"Cardiopulmonary bypass time does not affect cerebral blood flow","volume":"65","author":"Croughwell","year":"1998","journal-title":"Ann. Thorac. Surg."},{"key":"10.1006\/jsre.2001.6263_RF21","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1213\/00000539-199908000-00014","article-title":"The effect of hematocrit on cerebral blood flow velocity in neonates and infants undergoing deep hypothermic cardiopulmonary bypass","volume":"89","author":"Gruber","year":"1999","journal-title":"Anesth. Analg."},{"key":"10.1006\/jsre.2001.6263_RF22","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1097\/00002480-199907000-00003","article-title":"The inflammatory and coagulative response to prolonged extracorporeal membrane oxygenation","volume":"45","author":"Peek","year":"1999","journal-title":"ASAIO J."},{"key":"10.1006\/jsre.2001.6263_RF23","first-page":"156","article-title":"Relative vulnerability of neonatal and adult hearts to ischemic injury","volume":"76","author":"Wittnich","year":"1987","journal-title":"Circulation"},{"key":"10.1006\/jsre.2001.6263_RF24","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1016\/0003-4975(91)91267-Y","article-title":"Not all neonatal hearts are equally protected from ischemic damage during hypothermia","volume":"52","author":"Wittnich","year":"1991","journal-title":"Ann. Thorac. Surg."},{"key":"10.1006\/jsre.2001.6263_RF25","series-title":"Laboratory Animal Medicine","first-page":"273","article-title":"Ungulates as laboratory animals","author":"Brooks","year":"1984"}],"container-title":["Journal of Surgical Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022480401962638?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0022480401962638?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,20]],"date-time":"2025-09-20T14:35:39Z","timestamp":1758378939000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0022480401962638"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,12]]},"references-count":25,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2001,12]]}},"alternative-id":["S0022480401962638"],"URL":"https:\/\/doi.org\/10.1006\/jsre.2001.6263","relation":{},"ISSN":["0022-4804"],"issn-type":[{"value":"0022-4804","type":"print"}],"subject":[],"published":{"date-parts":[[2001,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A Long-Term Stable Normothermic Cardiopulmonary Bypass Model in Neonatal Swine","name":"articletitle","label":"Article Title"},{"value":"Journal of Surgical Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1006\/jsre.2001.6263","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2001 Elsevier Science (USA). All rights reserved.","name":"copyright","label":"Copyright"}]}}