{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T18:54:56Z","timestamp":1778612096063,"version":"3.51.4"},"reference-count":45,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2001,6,1]],"date-time":"2001-06-01T00:00:00Z","timestamp":991353600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecular and Cellular Neuroscience"],"published-print":{"date-parts":[[2001,6]]},"DOI":"10.1006\/mcne.2001.0990","type":"journal-article","created":{"date-parts":[[2002,9,18]],"date-time":"2002-09-18T15:46:43Z","timestamp":1032364003000},"page":"1094-1101","source":"Crossref","is-referenced-by-count":31,"title":["Bone Marrow Transfer from Wild-Type Mice Reverts the Beneficial Effect of Genetically Mediated Immune Deficiency in Myelin Mutants"],"prefix":"10.1006","volume":"17","author":[{"given":"Mathias","family":"M\u00e4urer","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph D.","family":"Schmid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank","family":"Bootz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00fcrgen","family":"Zielasek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Klaus V.","family":"Toyka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephan","family":"Oehen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rudolf","family":"Martini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1006\/mcne.2001.0990_RF1","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1212\/WNL.41.3.437","article-title":"Corticosteroid-responsive dominantly inherited neuropathy in childhood","volume":"41","author":"Bird","year":"1991","journal-title":"Neurology"},{"key":"10.1006\/mcne.2001.0990_RF2","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1086\/318208","article-title":"Periaxin mutations cause recessive Dejerine-Sottas neuropathy","volume":"68","author":"Boerkoel","year":"2001","journal-title":"Am. J. Hum. Genet."},{"key":"10.1006\/mcne.2001.0990_RF3","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1038\/75542","article-title":"Charcot-Marie-Tooth type 4B is caused by mutations in the gene encoding myotubularin-related protein-2","volume":"25","author":"Bolino","year":"2000","journal-title":"Nat. Genet."},{"key":"10.1006\/mcne.2001.0990_RF4","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1016\/0896-6273(94)90063-9","article-title":"Null mutations of connexin32 in patients with X-linked Charcot-Marie-Tooth disease","volume":"13","author":"Bruzzone","year":"1994","journal-title":"Neuron"},{"key":"10.1006\/mcne.2001.0990_RF5","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1083\/jcb.152.2.301","article-title":"The role of macrophages in demyelinating peripheral nervous system of mice heterozygously deficient in P0","volume":"152","author":"Carenini","year":"2001","journal-title":"J. Cell Biol."},{"key":"10.1006\/mcne.2001.0990_RF6","doi-asserted-by":"crossref","first-page":"3752","DOI":"10.1523\/JNEUROSCI.19-10-03752.1999","article-title":"Altered formation of hemichannels and gap junction channels caused by C-terminal connexin-32 mutations","volume":"19","author":"Castro","year":"1999","journal-title":"J. Neurosci."},{"key":"10.1006\/mcne.2001.0990_RF7","first-page":"500","article-title":"Morphometrical and ultrastructural evaluation of the sural nerve in children with Charcot-Marie-Tooth: Implication for pathogenesis and treatment","volume":"30","author":"Crawford","year":"1991","journal-title":"Ann. Neurol."},{"key":"10.1006\/mcne.2001.0990_RF8","doi-asserted-by":"crossref","first-page":"9077","DOI":"10.1523\/JNEUROSCI.17-23-09077.1997","article-title":"Altered trafficking of mutant connexin32","volume":"17","author":"Deschenes","year":"1997","journal-title":"J. Neurosci."},{"key":"10.1006\/mcne.2001.0990_RF9","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1523\/JNEUROSCI.18-02-00731.1998","article-title":"Overloaded endoplasmic reticulum-Golgi compartments, a possible pathomechanism of peripheral neuropathies caused by mutations of the peripheral myelin protein PMP22","volume":"18","author":"D'Urso","year":"1998","journal-title":"J. Neurosci."},{"key":"10.1006\/mcne.2001.0990_RF10","first-page":"239","article-title":"Prednisone-responsive hereditary motor and sensory neuropathy","volume":"57","author":"Dyck","year":"1982","journal-title":"Mayo Clin. Proc."},{"key":"10.1006\/mcne.2001.0990_RF11","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1002\/cne.901440207","article-title":"Control of myelin formation by axon caliber (with a model of the control mechanism)","volume":"144","author":"Friede","year":"1972","journal-title":"J. Comp. Neurol."},{"key":"10.1006\/mcne.2001.0990_RF12","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/0022-510X(92)90282-P","article-title":"Early morphological features in dominantly inherited demyelinating motor and sensory neuropathy (HMSN type I)","volume":"107","author":"Gabreels-Festen","year":"1992","journal-title":"J. Neurol. Sci."},{"key":"10.1006\/mcne.2001.0990_RF13","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1212\/WNL.50.4.1061","article-title":"Charcot-Marie-Tooth disease type 1A with 17p duplication in infancy and early childhood: A longitudinal clinical and electrophysiologic study","volume":"50","author":"Garcia","year":"1998","journal-title":"Neurology"},{"key":"10.1006\/mcne.2001.0990_RF14","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1111\/j.1750-3639.1999.tb00231.x","article-title":"Mechanisms of immune regulation in the peripheral nervous system","volume":"9","author":"Gold","year":"1999","journal-title":"Brain Pathol."},{"key":"10.1006\/mcne.2001.0990_RF15","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1002\/ana.410330615","article-title":"Coexistence of hereditary motor and sensory neuropathy type Ia and IgM paraproteinemic neuropathy","volume":"33","author":"Gregory","year":"1993","journal-title":"Ann. Neurol."},{"key":"10.1006\/mcne.2001.0990_RF16","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1093\/hmg\/10.4.415","article-title":"A mutation in periaxin is responsible for CMT4F, an autosomal recessive form of Charcot-Marie-Tooth disease","volume":"10","author":"Guilbot","year":"2001","journal-title":"Hum. Mol. Genet."},{"key":"10.1006\/mcne.2001.0990_RF17","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/S0166-2236(97)01222-8","article-title":"Pathogenesis of Charcot-Marie-Tooth IA (CMTIA) neuropathy","volume":"21","author":"Hanemann","year":"1998","journal-title":"Trends Neurosci."},{"key":"10.1006\/mcne.2001.0990_RF18","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1097\/00019052-199810000-00013","article-title":"Guillain-Barre syndrome, CIDP and other chronic immune-mediated neuropathies","volume":"11","author":"Hartung","year":"1998","journal-title":"Curr. Opin. Neurol."},{"key":"10.1006\/mcne.2001.0990_RF19","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1146\/annurev.neuro.21.1.187","article-title":"Human autoimmune neuropathies","volume":"21","author":"Ho","year":"1998","journal-title":"Ann. Rev. Neurosci."},{"key":"10.1006\/mcne.2001.0990_RF20","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1086\/302978","article-title":"N-myc downstream-regulated gene 1 is mutated in hereditary motor and sensory neuropathy-Lom","volume":"67","author":"Kalaydjieva","year":"2000","journal-title":"Am. J. Hum. Genet."},{"key":"10.1006\/mcne.2001.0990_RF21","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1172\/JCI5986","article-title":"Motor neuropathy in porphobilinogen deaminase-deficient mice imitiates the peripheral neuropathy of human acute porphyria","volume":"103","author":"Lindberg","year":"1999","journal-title":"J. Clin. Invest."},{"key":"10.1006\/mcne.2001.0990_RF22","doi-asserted-by":"crossref","first-page":"859","DOI":"10.1212\/WNL.52.4.859","article-title":"Acute inflammatory neuropathy in Charcot-Marie-Tooth disease","volume":"52","author":"Malandrini","year":"1999","journal-title":"Neurology"},{"key":"10.1006\/mcne.2001.0990_RF23","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1038\/ng1195-281","article-title":"Protein zero (P0)-deficient mice show myelin degeneration in peripheral nerves characteristic of inherited human neuropathies","volume":"11","author":"Martini","year":"1995","journal-title":"Nature Genet."},{"key":"10.1006\/mcne.2001.0990_RF24","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1046\/j.1469-7580.1997.19130321.x","article-title":"Animal models for inherited peripheral neuropathies","volume":"191","author":"Martini","year":"1997","journal-title":"J. Anat."},{"key":"10.1006\/mcne.2001.0990_RF25","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1002\/1097-4547(20000801)61:3<244::AID-JNR2>3.0.CO;2-R","article-title":"Animal models for inherited peripheral neuropathies: Chances to find treatment strategies","volume":"61","author":"Martini","year":"2000","journal-title":"J. Neurosci. Res."},{"key":"10.1006\/mcne.2001.0990_RF26","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1086\/302962","article-title":"A new variant of Charcot\u2013Marie\u2013Tooth disease type 2 is probably the result of a mutation in the neurofilament-light gene","volume":"67","author":"Mersiyanova","year":"2000","journal-title":"Am. J. Hum. Genet."},{"key":"10.1006\/mcne.2001.0990_RF27","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/0092-8674(92)90030-G","article-title":"RAG-1-deficient mice have no mature B and T lymphocytes","volume":"68","author":"Mombaerts","year":"1992","journal-title":"Cell"},{"key":"10.1006\/mcne.2001.0990_RF28","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1006\/mcne.1997.0604","article-title":"Aberrant protein trafficking in Trembler suggests a disease mechanism for hereditary human peripheral neuropathies","volume":"9","author":"Naef","year":"1997","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1006\/mcne.2001.0990_RF29","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1002\/(SICI)1098-1004(1999)13:1<11::AID-HUMU2>3.0.CO;2-A","article-title":"Mutations in the peripheral myelin genes and associated genes in inherited peripheral neuropathies","volume":"13","author":"Nelis","year":"1999","journal-title":"Hum. Mut."},{"key":"10.1006\/mcne.2001.0990_RF30","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1016\/S0896-6273(00)80973-3","article-title":"Changes in permeability caused by connexin 32 mutations underlie X-linked Charcot\u2013Marie\u2013Tooth disease","volume":"19","author":"Oh","year":"1997","journal-title":"Neuron"},{"key":"10.1006\/mcne.2001.0990_RF31","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1091\/mbc.7.6.907","article-title":"Connexin 32 mutations from X-linked Charcot\u2013Marie\u2013Tooth disease patients: Functional defects and dominant negative effects","volume":"7","author":"Omori","year":"1996","journal-title":"Mol. Biol. Cell."},{"key":"10.1006\/mcne.2001.0990_RF32","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1038\/342559a0","article-title":"Tolerance induction in double specific T-cell receptor transgenic mice varies with antigen","volume":"342","author":"Pircher","year":"1989","journal-title":"Nature"},{"key":"10.1006\/mcne.2001.0990_RF33","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/0014-5793(94)00819-1","article-title":"A connexin-32 mutation associated with Charcot\u2013Marie\u2013Tooth disease does not affect channel formation in oocytes","volume":"351","author":"Rabadan-Diehl","year":"1994","journal-title":"FEBS Lett."},{"key":"10.1006\/mcne.2001.0990_RF34","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1046\/j.1529-8027.2000.00014.x","article-title":"Chronic inflammatory demyelinating polyneuropathy caused by HIV infection in a patient with asymptomatic CMT1A","volume":"5","author":"Rajabally","year":"2000","journal-title":"J. Peripher. Nerv. Syst."},{"key":"10.1006\/mcne.2001.0990_RF35","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0165-5728(99)00250-7","article-title":"Characterisation of autoantibodies to peripheral myelin protein 22 in patients with hereditary and aquired neuropathies","volume":"104","author":"Ritz","year":"2000","journal-title":"J. Neuroimmunol."},{"key":"10.1006\/mcne.2001.0990_RF36","first-page":"175","article-title":"The role of the gap junction protein connexin32 in the pathogenesis of X-linked Charcot\u2013Marie\u2013Tooth disease","volume":"219","author":"Scherer","year":"1999","journal-title":"Novartis Found. Symp."},{"key":"10.1006\/mcne.2001.0990_RF37","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1523\/JNEUROSCI.20-02-00729.2000","article-title":"Immune deficiency in mouse models for inherited peripheral neuropathies leads to improved myelin maintenance","volume":"20","author":"Schmid","year":"2000","journal-title":"J. Neurosci."},{"key":"10.1006\/mcne.2001.0990_RF38","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1097\/00005072-199756070-00008","article-title":"Heterozygous P0 knock-out mice develop a peripheral neuropathy that resembles chronic inflammatory demyelinating polyneuropathy","volume":"56","author":"Shy","year":"1997","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1006\/mcne.2001.0990_RF39","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1749-6632.1999.tb08560.x","article-title":"Overview of Charcot\u2013Marie\u2013Tooth disease 1A","volume":"833","author":"Thomas","year":"1999","journal-title":"Ann. N.Y. Acad. Sci."},{"key":"10.1006\/mcne.2001.0990_RF40","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1038\/ng0498-382","article-title":"Mutations in the early growth response 2 (EGR2) gene are associated with hereditary myelinopathies","volume":"18","author":"Warner","year":"1998","journal-title":"Nat. Genet."},{"key":"10.1006\/mcne.2001.0990_RF41","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/0165-5728(92)90046-N","article-title":"Expression of Schwann cell and peripheral T-cell activation epitopes in hereditary motor and sensory neuropathy","volume":"36","author":"Williams","year":"1992","journal-title":"J. Neuroimmol."},{"key":"10.1006\/mcne.2001.0990_RF42","doi-asserted-by":"crossref","first-page":"1531","DOI":"10.1083\/jcb.134.6.1531","article-title":"Dominant-negative effect on adhesion by myelin P0 protein truncated in its cytoplasmic domain","volume":"134","author":"Wong","year":"1996","journal-title":"J. Cell Biol."},{"key":"10.1006\/mcne.2001.0990_RF43","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1002\/(SICI)1097-4547(19980115)51:2<154::AID-JNR4>3.0.CO;2-C","article-title":"Mutations of connexin32 in Charcot\u2013Marie\u2013Tooth disease type X interfere with cell-to-cell communication but not cell proliferation and myelin-specific gene expression","volume":"51","author":"Yoshimura","year":"1998","journal-title":"J. Neurosci. Res."},{"key":"10.1006\/mcne.2001.0990_RF44","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/(SICI)1097-4547(19980701)53:1<1::AID-JNR1>3.0.CO;2-F","article-title":"Myelin P0 protein mutated at Cys21 has a dominant effect on adhesive wild type P0","volume":"53","author":"Zhang","year":"1998","journal-title":"J. Neurosci. Res."},{"key":"10.1006\/mcne.2001.0990_RF45","doi-asserted-by":"crossref","first-page":"946","DOI":"10.1002\/(SICI)1097-4598(199608)19:8<946::AID-MUS2>3.0.CO;2-8","article-title":"Functional abnormalities in P0-deficient mice resemble human hereditary neuropathies linked to P0 gene mutations","volume":"19","author":"Zielasek","year":"1996","journal-title":"Muscle Nerve"}],"container-title":["Molecular and Cellular Neuroscience"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S104474310190990X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S104474310190990X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,12,16]],"date-time":"2019-12-16T22:22:36Z","timestamp":1576534956000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S104474310190990X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,6]]},"references-count":45,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2001,6]]}},"alternative-id":["S104474310190990X"],"URL":"https:\/\/doi.org\/10.1006\/mcne.2001.0990","relation":{},"ISSN":["1044-7431"],"issn-type":[{"value":"1044-7431","type":"print"}],"subject":[],"published":{"date-parts":[[2001,6]]}}}