{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T07:44:42Z","timestamp":1761291882609},"reference-count":23,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[1999,8,1]],"date-time":"1999-08-01T00:00:00Z","timestamp":933465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Molecular Genetics and Metabolism"],"published-print":{"date-parts":[[1999,8]]},"DOI":"10.1006\/mgme.1999.2875","type":"journal-article","created":{"date-parts":[[2002,9,18]],"date-time":"2002-09-18T19:46:30Z","timestamp":1032378390000},"page":"343-351","source":"Crossref","is-referenced-by-count":25,"title":["Systemic Infection Following Intravenous Inoculation of Mice with Candida albicans int1 Mutant Strains"],"prefix":"10.1006","volume":"67","author":[{"given":"Catherine M.","family":"Bendel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen M.","family":"Kinneberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert P.","family":"Jechorek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cheryl A.","family":"Gale","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stanley L.","family":"Erlandsen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Margaret K.","family":"Hostetter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carol L.","family":"Wells","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1006\/mgme.1999.2875_RF1","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1128\/CMR.7.1.29","article-title":"Adhesions and ligands involved in the interaction of Candida spp","volume":"7","author":"Hostetter","year":"1994","journal-title":"Clin Microbiol Rev"},{"key":"10.1006\/mgme.1999.2875_RF2","doi-asserted-by":"crossref","first-page":"S89","DOI":"10.1093\/clinids\/22.Supplement_2.S89","article-title":"Nosocomial candidiasis: Emerging species, reservoirs, and modes of transmission","volume":"22","author":"Pfaller","year":"1996","journal-title":"Clin Infect Dis"},{"key":"10.1006\/mgme.1999.2875_RF3","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/S0031-3955(16)36471-9","article-title":"Candida: An increasingly important pathogen in the nursery","volume":"35","author":"Butler","year":"1988","journal-title":"Pediatr Clin North Am"},{"key":"10.1006\/mgme.1999.2875_RF4","doi-asserted-by":"crossref","first-page":"S73","DOI":"10.1093\/clinids\/22.Supplement_2.S73","article-title":"The role of the gastrointestinal tract in hematogenous candidiasis: From the laboratory to the bedside","volume":"22","author":"Cole","year":"1996","journal-title":"Clin Infect Dis"},{"key":"10.1006\/mgme.1999.2875_RF5","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/S0002-9610(05)80666-X","article-title":"Candida sepsis in surgical patients","volume":"166","author":"Eubanks","year":"1993","journal-title":"Am J Surg"},{"key":"10.1006\/mgme.1999.2875_RF6","series-title":"Candida and Candidosis. A Review and Bibliography","author":"Odds","year":"1988"},{"key":"10.1006\/mgme.1999.2875_RF7","first-page":"1","article-title":"Systemic candidiasis and other fungal infections in the newborn","volume":"5","author":"Bendel","year":"1994","journal-title":"Semin Pediatr Infect Dis"},{"key":"10.1006\/mgme.1999.2875_RF8","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1001\/archinte.1995.00430110089009","article-title":"Nosocomial blood stream infections: Secular trends in rates, mortality, and contribution to total hospital deaths","volume":"155","author":"Pittet","year":"1995","journal-title":"Arch Intern Med"},{"key":"10.1006\/mgme.1999.2875_RF9","first-page":"S37","article-title":"Treatment of candidiasis: A perspective on recent advances and future challenges","volume":"1","author":"Todischini","year":"1997","journal-title":"J Intern Dis"},{"key":"10.1006\/mgme.1999.2875_RF10","doi-asserted-by":"crossref","first-page":"523","DOI":"10.2307\/30145226","article-title":"Candida species: Emerging hospital bloodstream pathogens","volume":"12","author":"Wenzel","year":"1991","journal-title":"Infect Control Hosp Epidemiol"},{"key":"10.1006\/mgme.1999.2875_RF11","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1146\/annurev.mi.45.100191.001155","article-title":"Putative virulence factors of Candida albicans","volume":"45","author":"Cutler","year":"1991","journal-title":"Annu Rev Microbiol"},{"key":"10.1006\/mgme.1999.2875_RF12","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1126\/science.279.5355.1355","article-title":"Linkage of adhesion, filamentous growth, and virulence in Candida albicans to a single gene, INT1","volume":"279","author":"Gale","year":"1998","journal-title":"Science"},{"key":"10.1006\/mgme.1999.2875_RF13","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.1093\/infdis\/171.6.1660","article-title":"Epithelial adhesion in yeast species: Correlation of surface expression of the integrin analog","volume":"171","author":"Bendel","year":"1995","journal-title":"J Infect Dis"},{"key":"10.1006\/mgme.1999.2875_RF14","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1073\/pnas.93.1.357","article-title":"Cloning and expression of a gene encoding an integrin-like protein in Candida albicans","volume":"93","author":"Gale","year":"1996","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1006\/mgme.1999.2875_RF15","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1093\/genetics\/134.3.717","article-title":"Isogenic strain construction and gene mapping in Candida albicans","volume":"134","author":"Fonzi","year":"1993","journal-title":"Genetics"},{"key":"10.1006\/mgme.1999.2875_RF16","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1128\/MCB.15.2.601","article-title":"PHR1, a pH-regulated gene of Candida albicans, is required for morphogenesis","volume":"15","author":"Saporito-Irwin","year":"1995","journal-title":"Mol Cell Biol"},{"key":"10.1006\/mgme.1999.2875_RF17","series-title":"Textbook of Diagnostic Microbiology","author":"Mahon","year":"1995"},{"key":"10.1006\/mgme.1999.2875_RF18","doi-asserted-by":"crossref","first-page":"7670","DOI":"10.1073\/pnas.95.13.7670","article-title":"Molecular analysis of CaMnt1p, a mannosyl transferase important for adhesion and virulence of Candida albicans","volume":"95","author":"Buurman","year":"1998","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1006\/mgme.1999.2875_RF19","doi-asserted-by":"crossref","first-page":"10570","DOI":"10.1073\/pnas.92.23.10570","article-title":"Attenuated virulence of chitin-deficient mutants of Candida albicans","volume":"92","author":"Bulawa","year":"1995","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1006\/mgme.1999.2875_RF20","doi-asserted-by":"crossref","first-page":"4515","DOI":"10.1128\/IAI.63.11.4515-4518.1995","article-title":"Reduced virulence of Candida albicans mutants affected in multidrug resistance","volume":"63","author":"Becker","year":"1995","journal-title":"Infect Immun"},{"key":"10.1006\/mgme.1999.2875_RF21","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1099\/00221287-143-2-377","article-title":"The topoisomerase gene from Candida albicans","volume":"143","author":"Jiang","year":"1997","journal-title":"Microbiology"},{"key":"10.1006\/mgme.1999.2875_RF22","doi-asserted-by":"crossref","first-page":"1535","DOI":"10.1126\/science.283.5407.1535","article-title":"Adhesive and mammalian transglutaminase substrate properties of Candida albicans Hwp1","volume":"283","author":"Staab","year":"1999","journal-title":"Science"},{"key":"10.1006\/mgme.1999.2875_RF23","unstructured":"Diez-Orejas, R, Molero, G, Navarro-Garcia, F, Pla, J, Nombela, C, Sanchez-Perez, M. Reduced virulence of Candida albicans MCK1 mutants: A role for mitogen-activated protein kinase in pathogenesis. Infect Immun65:833\u2013837, 1997."}],"container-title":["Molecular Genetics and Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1096719299928755?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1096719299928755?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,5,3]],"date-time":"2021-05-03T01:26:57Z","timestamp":1620005217000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1096719299928755"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,8]]},"references-count":23,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1999,8]]}},"alternative-id":["S1096719299928755"],"URL":"https:\/\/doi.org\/10.1006\/mgme.1999.2875","relation":{},"ISSN":["1096-7192"],"issn-type":[{"value":"1096-7192","type":"print"}],"subject":[],"published":{"date-parts":[[1999,8]]}}}