{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T17:29:24Z","timestamp":1761154164312},"reference-count":32,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2001,1,1]],"date-time":"2001-01-01T00:00:00Z","timestamp":978307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microbial Pathogenesis"],"published-print":{"date-parts":[[2001,1]]},"DOI":"10.1006\/mpat.2000.0405","type":"journal-article","created":{"date-parts":[[2002,9,18]],"date-time":"2002-09-18T19:46:30Z","timestamp":1032378390000},"page":"29-38","source":"Crossref","is-referenced-by-count":23,"title":["Early responses to Salmonella typhimurium infection in mice occur at focal lesions in infected organs"],"prefix":"10.1006","volume":"30","author":[{"given":"Shahid A","family":"Khan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul J.L.M.","family":"Strijbos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Everest","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Moss","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Stratford","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pietro","family":"Mastroeni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jenny","family":"Allen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Spiros","family":"Servos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ian G.","family":"Charles","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gordon","family":"Dougan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Duncan J.","family":"Maskell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1006\/mpat.2000.0405_RF1","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1128\/IAI.10.4.816-822.1974","article-title":"Growth of typhoid and paratyphoid bacilli in intravenously infected mice","volume":"10","author":"Carter","year":"1974","journal-title":"Infect Immun"},{"key":"10.1006\/mpat.2000.0405_RF2","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1084\/jem.139.5.1189","article-title":"The route of enteric infection in normal mice","volume":"139","author":"Carter","year":"1974","journal-title":"J Exp Med"},{"key":"10.1006\/mpat.2000.0405_RF3","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1128\/MR.53.4.390-409.1989","article-title":"Pathogenesis and immunity in murine salmonellosis","volume":"53","author":"Hsu","year":"1989","journal-title":"Microbio Rev"},{"key":"10.1006\/mpat.2000.0405_RF4","first-page":"223","article-title":"Immunity mechanisms in experimental salmonellosis","author":"Hormaeche","year":"1993","journal-title":"In: Cabello F, Hormaeche CE, Mastroeni P, Bonina L, Eds Biology of Salmonella. New York: Plenum Press"},{"key":"10.1006\/mpat.2000.0405_RF5","first-page":"303","article-title":"The intracellular nature of Salmonella infection during the early stages of mouse typhoid","volume":"60","author":"Dunlap","year":"1994","journal-title":"Immuno Ser"},{"key":"10.1006\/mpat.2000.0405_RF6","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1084\/jem.186.4.569","article-title":"Murine salmonellosis studied by confocal microscopy Salmonella typhimurium resides intracellularly inside macrophages and exerts a cytotoxic effect on phago\u00cdcytes in vivo","volume":"186","author":"Richter-Dahlfors","year":"1997","journal-title":"J Exp Med"},{"key":"10.1006\/mpat.2000.0405_RF7","first-page":"319","article-title":"Genetics of natural resistance to salmonellae in mice","volume":"37","author":"Hormaeche","year":"1979","journal-title":"Immunology"},{"key":"10.1006\/mpat.2000.0405_RF8","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/0092-8674(93)90135-D","article-title":"Natural resistance to infection with intracellular parasites: isolation of a candidate for Bcg","volume":"73","author":"Vidal","year":"1993","journal-title":"Cell"},{"key":"10.1006\/mpat.2000.0405_RF9","first-page":"311","article-title":"Natural resistance to Salmonella typhimurium in different inbred mouse strains","volume":"37","author":"Hormaeche","year":"1979","journal-title":"Immunology"},{"key":"10.1006\/mpat.2000.0405_RF10","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/0165-2478(94)00161-8","article-title":"Genetic regulation of leishmanial and mycobacterial infections: the Lsh\/Ity\/Bcg gene story continues","volume":"43","author":"Blackwell","year":"1994","journal-title":"Immunol Lett"},{"key":"10.1006\/mpat.2000.0405_RF11","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/0882-4010(87)90127-6","article-title":"The initial suppression of bacterial growth in a salmonella infection is mediated by a localized rather than a systemic response","volume":"4","author":"Maskell","year":"1987","journal-title":"Microb Pathog"},{"key":"10.1006\/mpat.2000.0405_RF12","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0882-4010(91)90091-N","article-title":"Serum TNF\u03b1 in mouse typhoid and enhancement of a Salmonella infection by anti-TNF\u03b1 antibodies","volume":"11","author":"Mastroeni","year":"1991","journal-title":"Microb Pathog"},{"key":"10.1006\/mpat.2000.0405_RF13","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/0882-4010(90)90077-4","article-title":"The role of IFN\u03b3 in the murine Salmonella typhimurium infection","volume":"8","author":"Muotiala","year":"1990","journal-title":"Microb Pathog"},{"key":"10.1006\/mpat.2000.0405_RF14","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1128\/IAI.60.2.450-454.1992","article-title":"Role of Gamma interferon and tumour necrosis factor alpha in resistance to Salmonella typhimurium infection","volume":"60","author":"Nauciel","year":"1992","journal-title":"Infect Immun"},{"key":"10.1006\/mpat.2000.0405_RF15","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1128\/IAI.64.1.189-196.1996","article-title":"Effect of interleukin-12 neutralization on host resistance and Gamma interferon production in mouse typhoid","volume":"64","author":"Mastroeni","year":"1996","journal-title":"Infect Immun"},{"key":"10.1006\/mpat.2000.0405_RF16","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1128\/IAI.67.2.478-483.1999","article-title":"Interleukin 18 contributes to host resistance and gamma interferon production in mice infected with virulent salmonella typhimurium","volume":"2","author":"Mastroeni","year":"1999","journal-title":"Infect Immun"},{"key":"10.1006\/mpat.2000.0405_RF17","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.4049\/jimmunol.129.4.1349","article-title":"Control of early Salmonella typhimurium growth in innately salmonella-resistant does not require functional T-lymphocytes","volume":"129","author":"O\u00bbBrien","year":"1982","journal-title":"J Immunol"},{"key":"10.1006\/mpat.2000.0405_RF18","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1128\/IAI.62.3.1089-1100.1994","article-title":"Nitric oxide produced during Murine listeriosis is protective","volume":"62","author":"Boocvar","year":"1994","journal-title":"Infect Immun"},{"key":"10.1006\/mpat.2000.0405_RF19","doi-asserted-by":"crossref","first-page":"3253","DOI":"10.1128\/IAI.63.9.3253-3258.1995","article-title":"In vivo regulation of replicative Legionella pneumophila lung infection by endogenous tumor necrosis factor alpha and nitric oxide","volume":"63","author":"Briedland","year":"1995","journal-title":"Infect Immun"},{"key":"10.1006\/mpat.2000.0405_RF20","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1128\/IAI.63.2.736-740.1995","article-title":"Effects of nitric oxide synthase inhibitors on murine infection with Mycobacterium tuberculosis","volume":"63","author":"Chan","year":"1995","journal-title":"Infect Immun"},{"key":"10.1006\/mpat.2000.0405_RF21","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1146\/annurev.immunol.15.1.323","article-title":"Nitric oxide and macrophage function","volume":"15","author":"Macmicking","year":"1997","journal-title":"Annu Rev Immunol"},{"key":"10.1006\/mpat.2000.0405_RF22","doi-asserted-by":"crossref","first-page":"2818","DOI":"10.1172\/JCI119473","article-title":"Perspectives series: host\/pathogen interactions. Mechanisms of nitric oxide-related antimicrobial activity","volume":"12","author":"Fang","year":"1997","journal-title":"J Clin Invest"},{"key":"10.1006\/mpat.2000.0405_RF23","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1073\/pnas.91.1.267","article-title":"Epithelial autotoxicity of nitric oxide: role in the respiratory cytopathology of pertussis","volume":"90","author":"Heiss","year":"1994","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1006\/mpat.2000.0405_RF24","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1128\/IAI.67.2.891-898.1999","article-title":"In vivo blockage of nitric oxide with aminoguanidine inhibits immunosuppression induced by an attenuated strain of salmonella typhimurium, potentiates salmonella \u00cdinfection, and inhibits macrophage and polymorphonuclear leukocyte influx into the spleen","volume":"67","author":"Macfarlane","year":"1999","journal-title":"Infect Immun"},{"key":"10.1006\/mpat.2000.0405_RF25","doi-asserted-by":"crossref","first-page":"3355","DOI":"10.1128\/IAI.66.7.3355-3364.1998","article-title":"Susceptibility to Salmonella typhimurium infection and effectiveness of vaccination in mice deficient in the tumor necrosis factor alpha p55 receptor","volume":"66","author":"Everest","year":"1998","journal-title":"Infect Immun"},{"key":"10.1006\/mpat.2000.0405_RF26","first-page":"348","article-title":"Cytokine stimulation during Salmonella typhimurium sepsis ItySmice","volume":"42","author":"Jotwani","year":"1996","journal-title":"Microb Pathogen"},{"key":"10.1006\/mpat.2000.0405_RF27","doi-asserted-by":"crossref","first-page":"1751","DOI":"10.1093\/intimm\/6.11.1751","article-title":"NADPH dia\u00cdphorase staining suggests a transient and localized contribution of nitric oxide to host defense against intracellular pathogen in situ","volume":"6","author":"Flesch","year":"1994","journal-title":"Int Immunol"},{"key":"10.1006\/mpat.2000.0405_RF28","doi-asserted-by":"crossref","first-page":"2932","DOI":"10.1128\/IAI.65.7.2932-2940.1997","article-title":"Induction of nitric oxide synthesis and xanthine oxidase and their roles in the antimicrobial mechanism againstSalmonella typhimurium infection in mice","volume":"65","author":"Umezawa","year":"1997","journal-title":"Infect Immun"},{"key":"10.1006\/mpat.2000.0405_RF29","article-title":"Molecular Cloning: A Laboratory Manual","author":"Sambrook","year":"1989","journal-title":"Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press"},{"key":"10.1006\/mpat.2000.0405_RF30","doi-asserted-by":"crossref","first-page":"6370","DOI":"10.1016\/S0021-9258(18)42704-4","article-title":"Molecular cloning and functional expression of an inducible nitric oxide from a murine macrophage cell line","volume":"267","author":"Lyons","year":"1992","journal-title":"J Biol Chem"},{"key":"10.1006\/mpat.2000.0405_RF31","doi-asserted-by":"crossref","first-page":"2719","DOI":"10.1172\/JCI118339","article-title":"Expression and localisation of inducible and endothelial nitric oxide synthase in the rat ovary","volume":"96","author":"Van Voorhis","year":"1995","journal-title":"J Clin Invest"},{"key":"10.1006\/mpat.2000.0405_RF32","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/0014-5793(91)81123-P","article-title":"Widespread tissue distribution, species distribution and changes in activity of Ca2+-dependent and Ca2+-independent nitric oxide synthases","volume":"291","author":"Salter","year":"1991","journal-title":"FEBS Lett"}],"container-title":["Microbial Pathogenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401000904054?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401000904054?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,4,4]],"date-time":"2023-04-04T03:58:49Z","timestamp":1680580729000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0882401000904054"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,1]]},"references-count":32,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2001,1]]}},"alternative-id":["S0882401000904054"],"URL":"https:\/\/doi.org\/10.1006\/mpat.2000.0405","relation":{},"ISSN":["0882-4010"],"issn-type":[{"value":"0882-4010","type":"print"}],"subject":[],"published":{"date-parts":[[2001,1]]}}}