{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T09:41:31Z","timestamp":1770716491030,"version":"3.49.0"},"reference-count":25,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2001,9,1]],"date-time":"2001-09-01T00:00:00Z","timestamp":999302400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microbial Pathogenesis"],"published-print":{"date-parts":[[2001,9]]},"DOI":"10.1006\/mpat.2001.0457","type":"journal-article","created":{"date-parts":[[2002,9,18]],"date-time":"2002-09-18T19:46:30Z","timestamp":1032378390000},"page":"145-150","source":"Crossref","is-referenced-by-count":21,"title":["Orientia tsutsugamushi suppresses the production of inflammatory cytokines induced by its own heat-stable component in murine macrophages"],"prefix":"10.1006","volume":"31","author":[{"given":"Mee-Kyung","family":"Kim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae-Seung","family":"Kang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1006\/mpat.2001.0457_RF1","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1128\/JCM.28.4.685-688.1990","article-title":"Serological classification by monoclonal antibodies of Rickettsia tsutsugamushi isolated in Korea","volume":"28","author":"Chang","year":"1990","journal-title":"J Clin Microbiol"},{"key":"10.1006\/mpat.2001.0457_RF2","doi-asserted-by":"crossref","first-page":"437","DOI":"10.3346\/jkms.1993.8.6.437","article-title":"Pathologic study of mice infected with Rickettsia tsutsugamushi R19 strain","volume":"8","author":"Hwang","year":"1993","journal-title":"J Korean Med Sci"},{"key":"10.1006\/mpat.2001.0457_RF3","doi-asserted-by":"crossref","first-page":"1068","DOI":"10.1128\/IAI.19.3.1068-1075.1978","article-title":"Experimental infection of mouse peritoneal mesothelium with scrub typhus rickettsiae: an ultrastructural study","volume":"19","author":"Ewing","year":"1978","journal-title":"Infect Immun"},{"key":"10.1006\/mpat.2001.0457_RF4","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1046\/j.1365-3156.1998.00231.x","article-title":"Electron-microscopic examination of Rickettsia tsutsugamushi-infected human liver","volume":"3","author":"Pongponratn","year":"1998","journal-title":"Trop Med Int Health"},{"key":"10.1006\/mpat.2001.0457_RF5","doi-asserted-by":"crossref","first-page":"2290","DOI":"10.1128\/IAI.55.9.2290-2292.1987","article-title":"Deficiency of peptidoglycan and lipopolysaccharide components in Rickettsia tsutsugamushi","volume":"55","author":"Amano","year":"1987","journal-title":"Infect Immun"},{"key":"10.1006\/mpat.2001.0457_RF6","doi-asserted-by":"crossref","first-page":"67","DOI":"10.7883\/yoken1952.38.67","article-title":"Pathology of toxic death in mice following intravenous injection of Rickettsia tsutsugamushi strain Gilliam: examination by light and scanning electron microscopy","volume":"38","author":"Oaks","year":"1985","journal-title":"Jpn J Med Sci Biol"},{"key":"10.1006\/mpat.2001.0457_RF7","doi-asserted-by":"crossref","first-page":"3320","DOI":"10.1128\/JCM.35.12.3320-3322.1997","article-title":"Increased levels of macrophage colony-stimulating factor, gamma interferon, and tumor necrosis factor alpha in sera of patients with Orientia tsutsugamushi infection","volume":"35","author":"Iwasaki","year":"1997","journal-title":"J Clin Microbiol"},{"key":"10.1006\/mpat.2001.0457_RF8","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1111\/j.1749-6632.1990.tb42218.x","article-title":"Tumor necrosis factor alpha and prostaglandin E2 production by human monocyte-derived macrophages infected with spotted fever group rickettsiae","volume":"590","author":"Manor","year":"1990","journal-title":"Ann N Y Acad Sci"},{"key":"10.1006\/mpat.2001.0457_RF9","doi-asserted-by":"crossref","first-page":"2568","DOI":"10.1128\/IAI.62.6.2568-2574.1994","article-title":"Relationship of tumor necrosis factor alpha, the nitric oxide synthase pathway, and lipopolysaccharide to the killing of gamma interferon-treated macrophagelike RAW264.7 cells by Rickettsia prowazekii","volume":"62","author":"Turco","year":"1994","journal-title":"Infect Immun"},{"key":"10.1006\/mpat.2001.0457_RF10","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1111\/j.1348-0421.1994.tb01846.x","article-title":"The role of tumor necrosis factor in host defense against scrub typhus rickettsiae. II. Differential induction of tumor necrosis factor-alpha production by Rickettsia tsutsugamushi and Rickettsia conorii","volume":"38","author":"Jerrells","year":"1994","journal-title":"Microbiol Immunol"},{"key":"10.1006\/mpat.2001.0457_RF11","doi-asserted-by":"crossref","first-page":"2544","DOI":"10.4049\/jimmunol.123.6.2544","article-title":"Macrophages in resistance to rickettsial infection: macrophage activation in vitro for killing of Rickettsia tsutsugamushi","volume":"123","author":"Nacy","year":"1979","journal-title":"J Immunol"},{"key":"10.1006\/mpat.2001.0457_RF12","doi-asserted-by":"crossref","first-page":"432","DOI":"10.1016\/S0171-2985(88)80024-X","article-title":"Quantitative immunocytochemical characterization of four macrophage-like cell lines","volume":"176","author":"Nibbering","year":"1988","journal-title":"Immunobiol"},{"key":"10.1006\/mpat.2001.0457_RF13","doi-asserted-by":"crossref","first-page":"894","DOI":"10.4049\/jimmunol.114.2_Part_2.894","article-title":"Identification of macrophage-like characteristics in a cultured murine cell line","volume":"114","author":"Koren","year":"1999","journal-title":"J Immunol"},{"key":"10.1006\/mpat.2001.0457_RF14","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1128\/BR.37.3.259-283.1973","article-title":"Growth and physiology of Rickettsiae","volume":"37","author":"Weiss","year":"1973","journal-title":"Bacteriol Rev"},{"key":"10.1006\/mpat.2001.0457_RF15","doi-asserted-by":"crossref","first-page":"2259","DOI":"10.4049\/jimmunol.162.4.2259","article-title":"IFN-\u03b3-mediated control of Coxiella burnetii survival in monocytes: the role of cell apoptosis and TNF","volume":"162","author":"Dellacasagrande","year":"1999","journal-title":"J Immunol"},{"key":"10.1006\/mpat.2001.0457_RF16","doi-asserted-by":"crossref","first-page":"3418","DOI":"10.1128\/IAI.59.10.3418-3423.1991","article-title":"Inhibition of Ehrlichia risticii infection in murine peritoneal macrophages by gamma interferon, a calcium ionophore, and concanavalin A","volume":"59","author":"Park","year":"1991","journal-title":"Infect Immun"},{"key":"10.1006\/mpat.2001.0457_RF17","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1128\/IAI.39.2.928-938.1983","article-title":"Effect of antibody on entry of Rickettsia tsutsugamushi into polymorphonuclear leukocyte cytoplasm","volume":"39","author":"Rikihisa","year":"1983","journal-title":"Infect Immun"},{"key":"10.1006\/mpat.2001.0457_RF18","doi-asserted-by":"crossref","first-page":"2401","DOI":"10.1128\/IAI.66.6.2401-2409.1998","article-title":"Bacterial perturbation of cytokine networks","volume":"66","author":"Wilson","year":"1998","journal-title":"Infect Immun"},{"key":"10.1006\/mpat.2001.0457_RF19","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1128\/IAI.21.3.1020-1023.1978","article-title":"Comparative ultrastructural study on the cell envelopes of Rickettsia prowazekii, Rickettsia rickettsii and Rickettsia tsutsugamushi","volume":"21","author":"Silverman","year":"1978","journal-title":"Infect Immun"},{"key":"10.1006\/mpat.2001.0457_RF20","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1128\/IAI.66.3.923-926.1998","article-title":"Structural properties of lipopolysaccharides from Rickettsia typhi and Rickettsia prowazekii and their chemical similarity to the lipopolysaccharide from Proteus vulgaris OX19 used in the Weil-Felix test","volume":"66","author":"Amano","year":"1998","journal-title":"Infect Immun"},{"key":"10.1006\/mpat.2001.0457_RF21","first-page":"21","article-title":"Structural and serological studies of the O-antigen of the bacterium Proteus mirabilis OXK (serogroup O3) used in the Weil-Felix test","volume":"62","author":"Swierzko","year":"1997","journal-title":"Biochemistry (Mosc)"},{"key":"10.1006\/mpat.2001.0457_RF22","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1128\/IAI.63.2.720-723.1995","article-title":"Differential induction of macrophage-derived cytokines by live and dead intracellular bacteria in vitro","volume":"63","author":"Zhan","year":"1995","journal-title":"Infect Immun"},{"key":"10.1006\/mpat.2001.0457_RF23","doi-asserted-by":"crossref","first-page":"2885","DOI":"10.4049\/jimmunol.156.8.2885","article-title":"Brucella species release a specific, protease-sensitive, inhibitor of TNF-\u03b1 expression, active on human macrophage-like cells","volume":"156","author":"Caron","year":"1996","journal-title":"J Immunol"},{"key":"10.1006\/mpat.2001.0457_RF24","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1111\/j.1348-0421.1999.tb02466.x","article-title":"Apoptosis of endothelial cell line ECV304 persistently infected with Orientia tsutsugamushi","volume":"43","author":"Kim","year":"1999","journal-title":"Microbiol Immunol"},{"key":"10.1006\/mpat.2001.0457_RF25","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/S0264-410X(00)00167-5","article-title":"Neutralization epitopes on antigenic domain II of the Orientia tsutsugamushi 56-kDa protein revealed by monoclonal antibodies","volume":"19","author":"Seong","year":"2000","journal-title":"Vaccine"}],"container-title":["Microbial Pathogenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401001904577?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401001904577?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T22:03:42Z","timestamp":1680559422000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0882401001904577"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,9]]},"references-count":25,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2001,9]]}},"alternative-id":["S0882401001904577"],"URL":"https:\/\/doi.org\/10.1006\/mpat.2001.0457","relation":{},"ISSN":["0882-4010"],"issn-type":[{"value":"0882-4010","type":"print"}],"subject":[],"published":{"date-parts":[[2001,9]]}}}