{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T08:40:37Z","timestamp":1778575237392,"version":"3.51.4"},"reference-count":40,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2002,5,1]],"date-time":"2002-05-01T00:00:00Z","timestamp":1020211200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Microbial Pathogenesis"],"published-print":{"date-parts":[[2002,5]]},"DOI":"10.1006\/mpat.2002.0500","type":"journal-article","created":{"date-parts":[[2002,9,18]],"date-time":"2002-09-18T19:46:30Z","timestamp":1032378390000},"page":"239-248","source":"Crossref","is-referenced-by-count":46,"title":["Brucella abortus siderophore2,3-dihydroxybenzoic acid (DHBA) facilitatesintracellular survival of the bacteria"],"prefix":"10.1006","volume":"32","author":[{"given":"Parent","family":"Michelle A.","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bellaire","family":"Bryan H.","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Murphy","family":"Erin A.","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"II","given":"Roop","family":"R. Martin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elzer","family":"Phillip H.","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baldwin","family":"Cynthia L.","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1006\/mpat.2002.0500_RF1","doi-asserted-by":"crossref","first-page":"3995","DOI":"10.1128\/IAI.69.6.3995-4006.2001","article-title":"Intracellular survival of Brucella in human monocyte involves conventional uptake but special phagosomes","volume":"69","author":"Rittig","year":"2001","journal-title":"Infect Immun"},{"key":"10.1006\/mpat.2002.0500_RF2","doi-asserted-by":"crossref","first-page":"4255","DOI":"10.1128\/IAI.68.7.4255-4263.2000","article-title":"Intracellular trafficking of Brucella abortus in J774 macrophages","volume":"68","author":"Arenas","year":"2000","journal-title":"Infect Immun"},{"key":"10.1006\/mpat.2002.0500_RF3","doi-asserted-by":"crossref","first-page":"4041","DOI":"10.1128\/IAI.67.8.4041-4047.1999","article-title":"Early Acidification of Phagosomes Containing Brucella suis is essential for intracellular survival in murine macrophage","volume":"67","author":"Porte","year":"1999","journal-title":"Infect Immun"},{"key":"10.1006\/mpat.2002.0500_RF4","doi-asserted-by":"crossref","first-page":"7375","DOI":"10.1128\/jb.176.23.7375-7377.1994","article-title":"Brucella abortus catalase is periplasmic protein lacking a standard signal sequence","volume":"176","author":"Sha","year":"1994","journal-title":"J Bacteriol"},{"key":"10.1006\/mpat.2002.0500_RF5","doi-asserted-by":"crossref","first-page":"5631","DOI":"10.1128\/JB.182.19.5631-5633.2000","article-title":"Identification of Brucella abortus OxyR and its role in control of catalase expression","volume":"182","author":"Kim","year":"2000","journal-title":"J Bacteriol"},{"key":"10.1006\/mpat.2002.0500_RF6","doi-asserted-by":"crossref","first-page":"2863","DOI":"10.1128\/IAI.60.7.2863-2869.1992","article-title":"Construction of Cu-Zn superoxide dismutase deletion mutants of Brucella abortus: Analysis of survivalin vitro in epithelial and phagocytic cells and in vivo in mice","volume":"60","author":"Tatum","year":"1992","journal-title":"Infect Immun"},{"key":"10.1006\/mpat.2002.0500_RF7","doi-asserted-by":"crossref","first-page":"4337","DOI":"10.1128\/IAI.65.10.4337-4340.1997","article-title":"Survival of a bacterioferritin deletion mutant of Brucella Melitensis 16M in human monocyte-derived macrophage","volume":"65","author":"Denoel","year":"1997","journal-title":"Infect Immun"},{"key":"10.1006\/mpat.2002.0500_RF8","doi-asserted-by":"crossref","unstructured":"Sigel, A, Sigel, H, Metal Ions In Biological Systems. Iron transport and storage in microorganisms, Plants and Animals. Vol. 35. 1998, New York, Marcel Dekker, Inc.","DOI":"10.1155\/MBD.1998.262a"},{"key":"10.1006\/mpat.2002.0500_RF9","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1146\/annurev.micro.54.1.881","article-title":"Iron metabolism in pathogenic bacteria","volume":"54","author":"Ratedge","year":"2000","journal-title":"Annu Rev Microbiol"},{"key":"10.1006\/mpat.2002.0500_RF10","doi-asserted-by":"crossref","first-page":"4496","DOI":"10.1128\/IAI.60.11.4496-4503.1992","article-title":"Identification of 2,3-dihydroxybenzoic acid as a Brucella abortus siderophore","volume":"60","author":"Lopez-Goni","year":"1992","journal-title":"Infect Immun"},{"key":"10.1006\/mpat.2002.0500_RF11","doi-asserted-by":"crossref","first-page":"2615","DOI":"10.1128\/IAI.67.5.2615-2618.1999","article-title":"The siderophore 2,3-dihydroxybenzoic acid is not required for virulence of Brucella abortus in BALB\/c mice","volume":"67","author":"Bellaire","year":"1999","journal-title":"Infect Immun"},{"key":"10.1006\/mpat.2002.0500_RF12","first-page":"1075","article-title":"Uptake and Metabolism of Iron and Molybdenum","author":"Earhart","year":"1997"},{"key":"10.1006\/mpat.2002.0500_RF13","first-page":"87","article-title":"Brucella abortus siderophore 2,3-dihydroxybenzoic acid protects brucellae from killing by macrophage","volume":"28","author":"Leonard","year":"1997","journal-title":"Vet Res"},{"key":"10.1006\/mpat.2002.0500_RF14","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1172\/JCI111249","article-title":"The respiratory burst of phagocytes","volume":"73","author":"Babior","year":"1984","journal-title":"J Clin Invest"},{"key":"10.1006\/mpat.2002.0500_RF15","doi-asserted-by":"crossref","first-page":"3983","DOI":"10.1128\/jb.169.9.3982-3987.1987","article-title":"Characterization of 2,3-dihydroxybenzoic acid from Nocardia asteroides GUH-2","volume":"169","author":"Feistner","year":"1987","journal-title":"J Bacteriol"},{"key":"10.1006\/mpat.2002.0500_RF16","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1006\/cimm.1993.1121","article-title":"Iron augments macrophage-mediated killing of Brucella abortus alone and in conjunction with interferon-\u03b3","volume":"148","author":"Jiang","year":"1993","journal-title":"Cell Immunol"},{"key":"10.1006\/mpat.2002.0500_RF17","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1128\/IAI.53.2.245-251.1986","article-title":"Comparison of living and nonliving vaccines for Brucella abortus in BALB\/c mice","volume":"53","author":"Montaraz","year":"1986","journal-title":"Infect Immun"},{"key":"10.1006\/mpat.2002.0500_RF18","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1046\/j.1365-2567.2001.01258.x","article-title":"Interferon-\u03b3 is crucial for preventing an increase of Brucella abortus organism in resistant C57BL\/6 but not in susceptible BALB\/c mice","volume":"103","author":"Murphy","year":"2001","journal-title":"Immunology"},{"key":"10.1006\/mpat.2002.0500_RF19","first-page":"226","article-title":"Ultrastructural morphometric analysis of Brucella abortus-infected trophoblasts in experimental placentitis. Bacterial replication occurs in rough endoplasmic reticulum","volume":"124","author":"Anderson","year":"1986","journal-title":"Am J Pathol"},{"key":"10.1006\/mpat.2002.0500_RF20","first-page":"530","article-title":"The chemical basis of the virulence of Brucella abortus. III. Foetal erythritol a cause of the localization ofBrucella abortus in pregnant cows","volume":"43","author":"Williams","year":"1962","journal-title":"Br J Exp Pathol"},{"key":"10.1006\/mpat.2002.0500_RF21","doi-asserted-by":"crossref","first-page":"1590","DOI":"10.1182\/blood.V71.6.1590.1590","article-title":"Gamma-interferon modulates human monocyte\/macrophage transferrin receptor expression","volume":"71","author":"Taetle","year":"1988","journal-title":"Blood"},{"key":"10.1006\/mpat.2002.0500_RF22","first-page":"104","article-title":"The role of erythritol in the tissue localization of the brucellae","volume":"46","author":"Keppie","year":"1965","journal-title":"Br J Exp Pathol"},{"key":"10.1006\/mpat.2002.0500_RF23","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1038\/193047a0","article-title":"Fetal Erythritol: A cause of the localization of Brucella abortus in bovine contagious abortion","volume":"193","author":"Smith","year":"1962","journal-title":"Nature"},{"key":"10.1006\/mpat.2002.0500_RF24","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0022-3476(05)81868-2","article-title":"Misinterpretation of iron-binding capacity in the presence of deferoxamine","volume":"118","author":"Bentur","year":"1991","journal-title":"J Pediatr"},{"key":"10.1006\/mpat.2002.0500_RF25","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1016\/S0022-3476(66)80457-2","article-title":"The measurement of iron and iron-binding capacity in plasma containing deferoxamine","volume":"68","author":"Gervirtz","year":"1966","journal-title":"J Pediatr"},{"key":"10.1006\/mpat.2002.0500_RF26","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1128\/IAI.64.2.629-636.1996","article-title":"Legionella pneumophila mutants that are defective for iron acquisition and assimilation and intracellular infection","volume":"64","author":"Pope","year":"1996","journal-title":"Infect Immun"},{"key":"10.1006\/mpat.2002.0500_RF27","doi-asserted-by":"crossref","first-page":"4539","DOI":"10.1128\/IAI.65.11.4539-4547.1997","article-title":"Response of Chlamydia trachomatis serovar E to iron restriction in vitro and evidence for iron-regulated chlamydial proteins","volume":"66","author":"Raulston","year":"1997","journal-title":"Infect Immun"},{"key":"10.1006\/mpat.2002.0500_RF28","doi-asserted-by":"crossref","first-page":"2258","DOI":"10.1128\/IAI.67.5.2258-2265.1999","article-title":"Ehrlichia chaffeensis and E. sennetsu, but not human granulocytic ehrlichiosis agent, colocalize with transferrin receptor and up-regulate transferrin receptor mRNA by activating iron-responsive protein 1","volume":"67","author":"Barnwall","year":"1999","journal-title":"Infect Immun"},{"key":"10.1006\/mpat.2002.0500_RF29","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1111\/j.1600-0897.1999.tb00463.x","article-title":"The emerging role of immunoregulation of fibrinogen-related procoagulant Fg12 in the success or spontaneous abortion of early pregnancy in mice and humans","volume":"42","author":"Clark","year":"1999","journal-title":"Am J Reprod Immunol"},{"key":"10.1006\/mpat.2002.0500_RF30","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1111\/j.1600-0897.1998.tb00423.x","article-title":"MHC class II gene silencing in trophoblast cells is caused by inhibition of CIITA expression","volume":"40","author":"Morris","year":"1998","journal-title":"Am J Reprod Immunol"},{"key":"10.1006\/mpat.2002.0500_RF31","doi-asserted-by":"crossref","first-page":"1834","DOI":"10.1128\/IAI.68.4.1834-1839.2000","article-title":"Impact of siderophore production on Pseudomonas aeruginosa infections in immunosuppressed mice","volume":"68","author":"Takase","year":"2000","journal-title":"Infect Immun"},{"key":"10.1006\/mpat.2002.0500_RF32","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1084\/jem.179.2.447","article-title":"Leishmania promastigotes evade interleukin 12 (IL-12) induction by macrophages and stimulate a broad range of cytokines from CD4+ T cells during initiation of infection","volume":"179","author":"Reiner","year":"1994","journal-title":"J Exp Med"},{"key":"10.1006\/mpat.2002.0500_RF33","first-page":"651","article-title":"Antibody-mediated protection against Brucella abortus in BALB\/c mice at successive periods after infection: variation between virulent strain 2308 and attenuated vaccine strain 19","volume":"82","author":"Elzer","year":"1994","journal-title":"Immunology"},{"key":"10.1006\/mpat.2002.0500_RF34","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1111\/j.1365-2958.1989.tb00281.x","article-title":"MicroReview: Iron and virulence in Shigella","volume":"3","author":"Payne","year":"1989","journal-title":"Mol Microbiol"},{"key":"10.1006\/mpat.2002.0500_RF35","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1128\/JB.66.1.82-91.1953","article-title":"The role of iron in the biology of Brucella suis; I. Growth and virulence","volume":"66","author":"Waring","year":"1953","journal-title":"J Bact"},{"key":"10.1006\/mpat.2002.0500_RF36","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1128\/IAI.61.1.124-134.1993","article-title":"Effects of cytokines on intracellular growth of Brucella abortus","volume":"61","author":"Jiang","year":"1993","journal-title":"Infect Immun"},{"key":"10.1006\/mpat.2002.0500_RF37","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1046\/j.1365-2249.2000.01295.x","article-title":"Growth of Brucella abortus in macrophages from resistant and susceptible mouse strains","volume":"121","author":"Sathiyaseelan","year":"2000","journal-title":"Clin Exp Immunol"},{"key":"10.1006\/mpat.2002.0500_RF38","doi-asserted-by":"crossref","unstructured":"Murray, HW, Granger, AM, Teitelbaum, RF, Gamma interferon-activated human macrophages and Toxoplasma gondii, Chlamydia psittaci, andLeishmania donovani: antimicrobial role of limiting intracellular iron, Infect Immun 1991, 59, 4684, 6","DOI":"10.1128\/IAI.59.12.4684-4686.1991"},{"key":"10.1006\/mpat.2002.0500_RF39","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/BF01404264","article-title":"Long-term culture of bovine trophoblastic cells","volume":"11","author":"Munson","year":"1988","journal-title":"J Tissue Cult Methods"},{"key":"10.1006\/mpat.2002.0500_RF40","first-page":"229","article-title":"Invasion and Replication of Brucella abortus in three different trophoblastic cell lines","volume":"41","author":"Samartino","year":"1994","journal-title":"Zentralbl Veterinarmed [B]"}],"container-title":["Microbial Pathogenesis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401002905000?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0882401002905000?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,3,5]],"date-time":"2020-03-05T13:03:49Z","timestamp":1583413429000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0882401002905000"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,5]]},"references-count":40,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2002,5]]}},"alternative-id":["S0882401002905000"],"URL":"https:\/\/doi.org\/10.1006\/mpat.2002.0500","relation":{},"ISSN":["0882-4010"],"issn-type":[{"value":"0882-4010","type":"print"}],"subject":[],"published":{"date-parts":[[2002,5]]}}}