{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T13:15:30Z","timestamp":1772889330416,"version":"3.50.1"},"reference-count":21,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2001,11,1]],"date-time":"2001-11-01T00:00:00Z","timestamp":1004572800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pharmacological Research"],"published-print":{"date-parts":[[2001,11]]},"DOI":"10.1006\/phrs.2001.0869","type":"journal-article","created":{"date-parts":[[2002,9,18]],"date-time":"2002-09-18T20:38:41Z","timestamp":1032381521000},"page":"373-375","source":"Crossref","is-referenced-by-count":17,"title":["Effects of daily oral administration of rifaximin and neomycin on faecal aerobic flora in rats"],"prefix":"10.1006","volume":"44","author":[{"given":"P.A.","family":"Miglioli","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Allerberger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.B.","family":"Calabr\u00f2","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.M.","family":"Gaion","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1006\/phrs.2001.0869_RF1","doi-asserted-by":"crossref","first-page":"467","DOI":"10.2165\/00003495-199549030-00009","article-title":"Rifaximin: a review of its antibacterial activity, pharmacokinetic properties and therapeutic potential in conditions mediated by gastrointestinal bacteria","volume":"49","author":"Gillis","year":"1995","journal-title":"Drugs"},{"key":"10.1006\/phrs.2001.0869_RF2","doi-asserted-by":"crossref","first-page":"1821","DOI":"10.1056\/NEJM199306243282507","article-title":"Prevention and treatment of traveller\u2019s diarrhoea","volume":"328","author":"DuPont","year":"1993","journal-title":"N Engl J Med"},{"key":"10.1006\/phrs.2001.0869_RF3","first-page":"131","article-title":"Comparison of two non-absorbable antibiotics for treatment of enteritis in children","volume":"2","author":"Beseghi","year":"1998","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"10.1006\/phrs.2001.0869_RF4","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1159\/000007580","article-title":"Rifaximin: a nonabsorbed antimicrobial in therapy of travellers\u2019 diarrhoea","volume":"59","author":"DuPont","year":"1998","journal-title":"Digestion"},{"key":"10.1006\/phrs.2001.0869_RF5","first-page":"403","article-title":"Rifaximine versus neomycin in the treatment of portosystemic encephalopathy","volume":"23","author":"Di Piazza","year":"1991","journal-title":"Ital J Gastroenterol"},{"key":"10.1006\/phrs.2001.0869_RF6","first-page":"27","article-title":"Review\u2014antibiotic treatment in inflammatory bowel disease","volume":"3","author":"Giochetti","year":"1999","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"10.1006\/phrs.2001.0869_RF7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1159\/000238165","article-title":"Pharmacokinetics of L\/105, a new rifamycin, in rats and dogs, after oral administration","volume":"29","author":"Venturini","year":"1983","journal-title":"Chemotherapy"},{"key":"10.1006\/phrs.2001.0869_RF8","first-page":"257","article-title":"In-vitro and in-vivo evaluation of L\/105, a new topical intestinal rifamycin","volume":"V","author":"Venturini","year":"1986","journal-title":"Chemioterapia"},{"key":"10.1006\/phrs.2001.0869_RF9","first-page":"373","article-title":"Rifaximin (L\/105), a new topical intestinal antibiotic: pharmacokinetic study after single oral administration of 3H-rifaximin to rats","volume":"3","author":"Cellai","year":"1984","journal-title":"Chemioterapia"},{"key":"10.1006\/phrs.2001.0869_RF10","first-page":"471","article-title":"A simplified method for evaluation of human faecal flora in clinical practice","volume":"32","author":"Bertazzoni","year":"1977","journal-title":"Helv Paediat Acta"},{"key":"10.1006\/phrs.2001.0869_RF11","doi-asserted-by":"crossref","first-page":"53","DOI":"10.3109\/08910609309141562","article-title":"Effects of six antimicrobial drugs on rat intestinal flora: is the rat model of predictive value in clinical practice?","volume":"6","author":"Bertazzoni","year":"1993","journal-title":"Microbial Ecology Health Disease"},{"key":"10.1006\/phrs.2001.0869_RF12","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1002\/path.1700820108","article-title":"Faecal bacterial flora of animals and man: its development in young","volume":"82","author":"Smith","year":"1961","journal-title":"J Path Bact"},{"key":"10.1006\/phrs.2001.0869_RF13","first-page":"263","article-title":"Acute subacute, chronic toxicity and mutagenicity studies of rifaximin (L\/105) in rats","volume":"5","author":"Borelli","year":"1986","journal-title":"Chemioterapia"},{"key":"10.1006\/phrs.2001.0869_RF14","first-page":"99","article-title":"Valutazione comparativa in \u2018vivo\u2019 dell\u2019 attivit\u00e0 di farmaci antibatterici sulla flora fecale aerobia","volume":"69","author":"Bertazzoni Minelli","year":"1974","journal-title":"Clin Terap"},{"key":"10.1006\/phrs.2001.0869_RF15","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1017\/S0022172400060897","article-title":"Binding to and antibacterial effect of ampicillin, neomycin and polymyxin B on human faeces","volume":"93","author":"Hazenberg","year":"1984","journal-title":"J Hyg Camb"},{"key":"10.1006\/phrs.2001.0869_RF16","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1017\/S0022172400060897","article-title":"Binding to and antibacterial effect of ampicillin, neomycin and polymyxin B on human faeces","volume":"93","author":"Hazenberg","year":"1984","journal-title":"J Hyg Camb"},{"key":"10.1006\/phrs.2001.0869_RF17","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/BF00393667","article-title":"Effects of antibiotics on the human intestinal flora in mice","volume":"49","author":"Hazenberg","year":"1983","journal-title":"Antonie Van Leeuwenhoek"},{"key":"10.1006\/phrs.2001.0869_RF18","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1128\/AAC.24.4.560","article-title":"Antibacterial activity of norfloxacin in the gastrointestinal tracts of rats","volume":"24","author":"Frimodt-Moller","year":"1983","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1006\/phrs.2001.0869_RF19","doi-asserted-by":"crossref","first-page":"1869","DOI":"10.1128\/AAC.32.12.1869","article-title":"Norfloxacin binds to human faecal material","volume":"32","author":"Edlung","year":"1988","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1006\/phrs.2001.0869_RF20","first-page":"360","article-title":"Antibiotics and their interaction with intestinal contents","volume":"25","author":"Bertazzoni Minelli","year":"1995","journal-title":"Microecology Therapy"},{"key":"10.1006\/phrs.2001.0869_RF21","series-title":"The lactic acid bacteria. Health and Disease","first-page":"21","article-title":"The lactic microflora of pigs, mice and rats","author":"Tannock","year":"1992"}],"container-title":["Pharmacological Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043661801908692?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1043661801908692?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,8]],"date-time":"2019-05-08T16:53:35Z","timestamp":1557334415000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1043661801908692"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,11]]},"references-count":21,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2001,11]]}},"alternative-id":["S1043661801908692"],"URL":"https:\/\/doi.org\/10.1006\/phrs.2001.0869","relation":{},"ISSN":["1043-6618"],"issn-type":[{"value":"1043-6618","type":"print"}],"subject":[],"published":{"date-parts":[[2001,11]]}}}