{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T05:21:22Z","timestamp":1767676882028},"reference-count":49,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[1998,5,1]],"date-time":"1998-05-01T00:00:00Z","timestamp":893980800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Toxicology and Applied Pharmacology"],"published-print":{"date-parts":[[1998,5]]},"DOI":"10.1006\/taap.1998.8385","type":"journal-article","created":{"date-parts":[[2002,9,18]],"date-time":"2002-09-18T22:01:25Z","timestamp":1032386485000},"page":"22-31","source":"Crossref","is-referenced-by-count":4,"title":["Enhanced Regional Expression of GlutathioneS-Transferase P1-1 with Colocalized AP-1 and CYP 1A2 Induction in Chlorobenzene-Induced Porphyria"],"prefix":"10.1006","volume":"150","author":[{"given":"Russell S.","family":"Thomas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel L.","family":"Gustafson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Howard S.","family":"Ramsdell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hisham A.","family":"El-Masri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen A.","family":"Benjamin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raymond S.H.","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1006\/taap.1998.8385_TO988385RF1","doi-asserted-by":"crossref","first-page":"2487","DOI":"10.1016\/0006-2952(78)90314-3","article-title":"The influence of phenobarbital, 3-methylcholanthrene and 2,3,7,8-tetrachlorodibenzo-p-dioxin on glutathioneS-transferase activity of rat liver cytosol","volume":"27","author":"Baars","year":"1978","journal-title":"Biochem. Pharmacol."},{"key":"10.1006\/taap.1998.8385_TO988385RF2","first-page":"4219","article-title":"Effects of disulfiram, diethyldithiocarbamate, bisethylxanthogen, and benzyl isothiocyanate on glutathione transferase activities in mouse organs","volume":"45","author":"Benson","year":"1985","journal-title":"Cancer Res."},{"key":"10.1006\/taap.1998.8385_TO988385RF3","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1042\/bj2940301","article-title":"Effect of lead acetate and carbon particles on the expression of glutathioneS-transferase YfYf in rat liver","volume":"294","author":"Boyce","year":"1993","journal-title":"Biochem. J."},{"key":"10.1006\/taap.1998.8385_TO988385RF4","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1093\/carcin\/15.6.1143","article-title":"Effects of 2,3,7,8-tetrachloro- and 1,2,3,4,6,7,8-heptachlorodibenzo-p-dioxin on the proliferation of preneoplastic liver cells in the rat","volume":"15","author":"Buchmann","year":"1994","journal-title":"Carcinogenesis (London)"},{"key":"10.1006\/taap.1998.8385_TO988385RF5","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/0304-3835(95)04089-7","article-title":"Medium-term bioassay for the hepatocarcinogenicity of hexachlorobenzene","volume":"100","author":"Cabral","year":"1996","journal-title":"Cancer Lett."},{"key":"10.1006\/taap.1998.8385_TO988385RF6","first-page":"170","article-title":"The oxidative stress response","volume":"3","author":"Camhi","year":"1995","journal-title":"New Horizons"},{"key":"10.1006\/taap.1998.8385_TO988385RF7","doi-asserted-by":"crossref","first-page":"173","DOI":"10.3109\/10409239309086794","article-title":"GlutathioneS-transferases: Gene structure and regulation of expression","volume":"28","author":"Daniel","year":"1993","journal-title":"Crit. Rev. Biochem. Mol. Biol."},{"key":"10.1006\/taap.1998.8385_TO988385RF8","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1006\/taap.1993.1059","article-title":"The role of oxidative metabolism in hexachlorobenzene-induced porphyria and thyroid hormone homeostasis: A comparison with pentachlorobenzene in a 13-week feeding study","volume":"119","author":"den Besten","year":"1993","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1006\/taap.1998.8385_TO988385RF9","doi-asserted-by":"crossref","first-page":"5153","DOI":"10.1093\/nar\/20.19.5153","article-title":"The dyad palindromic glutathione transferase P enhancer binds multiple factors including AP1","volume":"20","author":"Diccianni","year":"1992","journal-title":"Nucleic Acids Res."},{"key":"10.1006\/taap.1998.8385_TO988385RF10","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/0045-6535(92)90505-L","article-title":"Relative liver tumor promoting activity of some polychlorinated dibenzo-p-dioxin-, dibenzofuran-, and bipenyl-congeners in female rats","volume":"25","author":"Flodstr\u00f6m","year":"1996","journal-title":"Chemosphere"},{"key":"10.1006\/taap.1998.8385_TO988385RF11","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/0006-291X(87)90683-8","article-title":"Polycyclic aromatic hydrocarbons cause hepatic porphyria in iron-loaded c57BL\/10 mice: Comparison of uroporphrinogen decarboxylase inhibition with induction of alkoxyphenoxazone dealkylations","volume":"146","author":"Francis","year":"1987","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1006\/taap.1998.8385_TO988385RF12","series-title":"Carcinogenesis","article-title":"Hepatocarcinogenesis in the rat","author":"Hasegawa","year":"1994"},{"key":"10.1006\/taap.1998.8385_TO988385RF13","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1042\/bj1810699","article-title":"Identification of two lithocholic acid-binding proteins. Separation of ligandin from glutathioneS-transferase B","volume":"181","author":"Hayes","year":"1979","journal-title":"Biochem. J."},{"key":"10.1006\/taap.1998.8385_TO988385RF14","first-page":"163","article-title":"Relative tumour promoting activity of three polychlorinated biphenyls in rat liver","volume":"248","author":"Hemming","year":"1993","journal-title":"Eur. J. Pharmacol."},{"key":"10.1006\/taap.1998.8385_TO988385RF15","series-title":"Review of Pesticide Toxicology","first-page":"115","article-title":"Medium-termin vivobioassays for carcinogenicity of pesticides","author":"Ito","year":"1993"},{"key":"10.1006\/taap.1998.8385_TO988385RF16","doi-asserted-by":"crossref","first-page":"5317","DOI":"10.1021\/bi00016a003","article-title":"Three-dimensional structure, catalytic properties, and evolution of a sigma class glutathione transferase from squid, a progenitor of the lens S-crystallins of cephalopods","volume":"34","author":"Ji","year":"1995","journal-title":"Biochemistry"},{"key":"10.1006\/taap.1998.8385_TO988385RF17","first-page":"135","article-title":"Frequency of occurrence of hepatocellular carcinoma in patients with porphyria cutanea tarda in long-term follow-up","volume":"19","author":"Kordac","year":"1972","journal-title":"Neoplasma"},{"key":"10.1006\/taap.1998.8385_TO988385RF18","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1038\/336646a0","article-title":"The role of the leucine zipper in the fos-jun interaction","volume":"336","author":"Kouzarides","year":"1988","journal-title":"Nature"},{"key":"10.1006\/taap.1998.8385_TO988385RF19","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/0272-0590(91)90194-9","article-title":"Development of an experimental model for the study of hexachlorobenzene-induced hepatic porphyria in the rat","volume":"17","author":"Krishnan","year":"1991","journal-title":"Fundam. Appl. Toxicol."},{"key":"10.1006\/taap.1998.8385_TO988385RF20","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1042\/bj2690437","article-title":"Inhibition of uroporphyrinogen decarboxylase activity: The role of cytochrome P-450-mediated uroporphyrinogen oxidation","volume":"269","author":"Lambrecht","year":"1990","journal-title":"Biochem. J."},{"key":"10.1006\/taap.1998.8385_TO988385RF21","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/0003-9861(92)90717-B","article-title":"Uroporphyrinogen oxidation catalyzed by reconsituted cytochrome P4501A2","volume":"294","author":"Lambrecht","year":"1996","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1006\/taap.1998.8385_TO988385RF22","doi-asserted-by":"crossref","first-page":"7202","DOI":"10.1073\/pnas.82.21.7202","article-title":"Identification of three classes of cytosolic glutathione transferase common to several mammalian species: Correlation between structural data and enzymatic properties","volume":"82","author":"Mannervik","year":"1985","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1006\/taap.1998.8385_TO988385RF23","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1289\/ehp.93101634","article-title":"Dose response for TCDD promotion of hepatocarcinogenesis in rats initiated with DEN: Histologic, biochemical, and cell proliferation endpoints","volume":"101","author":"Maronpot","year":"1993","journal-title":"Environ. Health Perspect."},{"key":"10.1006\/taap.1998.8385_TO988385RF24","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1042\/bj2740409","article-title":"Theta, a new class of glutathione transferases purified from rat and man","volume":"274","author":"Meyer","year":"1991","journal-title":"Biochem. J."},{"key":"10.1006\/taap.1998.8385_TO988385RF25","doi-asserted-by":"crossref","first-page":"2065","DOI":"10.1073\/pnas.90.5.2065","article-title":"Trans-activation of glutathione transferase P gene during chemical hepatocarcinogenesis of the rat","volume":"90","author":"Morimura","year":"1993","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1006\/taap.1998.8385_TO988385RF26","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1038\/338589a0","article-title":"Two functionally different regions in Fos are required for the sequence-specific DNA interaction of the Fos\/Jun protein complex","volume":"338","author":"Neuberg","year":"1989","journal-title":"Nature"},{"key":"10.1006\/taap.1998.8385_TO988385RF27","doi-asserted-by":"crossref","first-page":"13656","DOI":"10.1016\/S0021-9258(17)36880-1","article-title":"Transcriptional regulation of a rat liver glutathioneS-transferase Ya subunit gene. Analysis of the antioxidant response element and its activation by the phorbol ester 12-O-tetradecanoylphorbol-13-acetate","volume":"269","author":"Nguyen","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1006\/taap.1998.8385_TO988385RF28","doi-asserted-by":"crossref","first-page":"16919","DOI":"10.1016\/S0021-9258(19)84795-6","article-title":"Structural and functional analysis of an enhancer GPEI having a phorbol 12-O-tetradecanoate 13-acetate responsive element-like sequence found in the rat glutathione transferase P gene","volume":"264","author":"Okuda","year":"1989","journal-title":"J. Biol. Chem."},{"key":"10.1006\/taap.1998.8385_TO988385RF29","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1002\/j.1460-2075.1990.tb08219.x","article-title":"Functional cooperativity between two TPA responsive elements in undifferentiated F9 embryonic stem cells","volume":"9","author":"Okuda","year":"1990","journal-title":"EMBO J."},{"key":"10.1006\/taap.1998.8385_TO988385RF30","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/0167-4781(94)90077-9","article-title":"Jun and Fos related gene products bind to and modulate the GPE I, a strong enhancer element of the rat glutathione transferase P gene","volume":"1219","author":"Oridate","year":"1994","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1006\/taap.1998.8385_TO988385RF31","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1159\/000225998","article-title":"Is porphyria cutanea tarda a risk factor in the development of hepatocelluar carcinoma","volume":"42","author":"Packe","year":"1985","journal-title":"Oncology"},{"key":"10.1006\/taap.1998.8385_TO988385RF32","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1038\/bjc.1987.24","article-title":"Porphyria and hepatocellular carcinoma","volume":"55","author":"Pierach","year":"1987","journal-title":"Br. J. Cancer"},{"key":"10.1006\/taap.1998.8385_TO988385RF33","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1006\/bbrc.1993.1168","article-title":"Enhanced glutathioneS-transferase 7-7 expression in rat hepatic cytosol following treatment with pyrrole","volume":"190","author":"Primiano","year":"1993","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1006\/taap.1998.8385_TO988385RF34","doi-asserted-by":"crossref","first-page":"11632","DOI":"10.1016\/S0021-9258(18)99004-6","article-title":"The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity","volume":"266","author":"Rushmore","year":"1991","journal-title":"J. Biol. Chem."},{"key":"10.1006\/taap.1998.8385_TO988385RF35","doi-asserted-by":"crossref","first-page":"9456","DOI":"10.1073\/pnas.85.24.9456","article-title":"Multiple regulatory elements and phorbol 12-O-tetradecanoate 13-acetate responsiveness of the rat placental glutathione transferase gene","volume":"85","author":"Sakai","year":"1988","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1006\/taap.1998.8385_TO988385RF36","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1016\/0006-291X(92)91293-Y","article-title":"Suppression of glutathione transferase P expression by glucocorticoid","volume":"187","author":"Sakai","year":"1992","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1006\/taap.1998.8385_TO988385RF37","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1038\/336692a0","article-title":"Direct interaction between fos and jun nuclear oncoproteins: Role of the \u2018leucine zipper\u2019 domain","volume":"336","author":"Sassone-Corsi","year":"1988","journal-title":"Nature"},{"key":"10.1006\/taap.1998.8385_TO988385RF38","doi-asserted-by":"crossref","first-page":"2059","DOI":"10.1016\/0006-2952(90)90236-E","article-title":"Sex-linked hepatic uroporphyria and the induction of cytochromes P450IA in rats caused by hexachlorobenzene and polyhalogenated biphenyls","volume":"40","author":"Smith","year":"1990","journal-title":"Biochem. Pharmacol."},{"key":"10.1006\/taap.1998.8385_TO988385RF39","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1093\/carcin\/14.7.1381","article-title":"Enhancement by iron of hepatic neoplasia in rats caused by hexachlorobenzene","volume":"14","author":"Smith","year":"1993","journal-title":"Carcinogenesis"},{"key":"10.1006\/taap.1998.8385_TO988385RF40","doi-asserted-by":"crossref","first-page":"865","DOI":"10.3109\/00498259009046902","article-title":"Oxidative injury mediated by the hepatic cytochrome P-450 system in conjunction with cellular iron: Effects on the pathway of haem biosynthesis","volume":"20","author":"Smith","year":"1990","journal-title":"Xenobiotica"},{"key":"10.1006\/taap.1998.8385_TO988385RF41","first-page":"769","article-title":"Enhancement of glutathioneS-transferase activity of the mouse forestomach by inhibitors of benzo[a]pyrene-induced neoplasia of the forestomach","volume":"66","author":"Sparnins","year":"1981","journal-title":"J. Natl. Cancer Inst."},{"key":"10.1006\/taap.1998.8385_TO988385RF42","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1093\/carcin\/16.6.1271","article-title":"Inhibition of apoptosis during 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated tumour promotion in rat liver","volume":"16","author":"Stinchcombe","year":"1995","journal-title":"Carcinogenesis (London)"},{"key":"10.1006\/taap.1998.8385_TO988385RF43","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1093\/carcin\/16.3.567","article-title":"Lack of correlated expression between the glutathioneS-transferase P-form and the oncogene products c-Junand c-Fosin rat tissues and preneoplastic hepatic foci","volume":"16","author":"Suzuki","year":"1995","journal-title":"Carcinogenesis (London)"},{"key":"10.1006\/taap.1998.8385_TO988385RF44","first-page":"2651","article-title":"Identification of an enhancer responsible for tumor marker gene expression by means of transgenic rats","volume":"55","author":"Suzuki","year":"1995","journal-title":"Cancer Res."},{"key":"10.1006\/taap.1998.8385_TO988385RF45","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0009-9120(86)80064-9","article-title":"Porphyria cutanea tarda, or the uroporphyrinogen decarboxylase deficiency diseases","volume":"19","author":"Sweeney","year":"1986","journal-title":"Clin. Biochem."},{"key":"10.1006\/taap.1998.8385_TO988385RF46","first-page":"1833","article-title":"Symptomatic porphyria. Part II. Hepatic changes with hexachlorobenzene","volume":"48","author":"Timme","year":"1974","journal-title":"S. Afr. Med. J."},{"key":"10.1006\/taap.1998.8385_TO988385RF47","doi-asserted-by":"crossref","first-page":"3795","DOI":"10.1016\/0006-2952(87)90439-4","article-title":"Hexachlorobenzene-induced oxygen activiation by mouse liver microsomes: Comparison with phenobarbitone and 20-methylcholanthrene","volume":"36","author":"Urquhart","year":"1987","journal-title":"Biochem. Pharmacol."},{"key":"10.1006\/taap.1998.8385_TO988385RF48","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1016\/0006-2952(88)90513-8","article-title":"Differential induction of rat hepatic glutathioneS-transferase isoenzyzmes by hexachlorobenzene and benzyl isothiocyanate","volume":"37","author":"Vos","year":"1988","journal-title":"Biochem. Pharmacol."},{"key":"10.1006\/taap.1998.8385_TO988385RF49","doi-asserted-by":"crossref","first-page":"3323","DOI":"10.1002\/j.1460-2075.1992.tb05411.x","article-title":"Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme","volume":"11","author":"Xanthoudakis","year":"1992","journal-title":"EMBO J."}],"container-title":["Toxicology and Applied Pharmacology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041008X98983855?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041008X98983855?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,5,3]],"date-time":"2021-05-03T02:40:27Z","timestamp":1620009627000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0041008X98983855"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,5]]},"references-count":49,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1998,5]]}},"alternative-id":["S0041008X98983855"],"URL":"https:\/\/doi.org\/10.1006\/taap.1998.8385","relation":{},"ISSN":["0041-008X"],"issn-type":[{"value":"0041-008X","type":"print"}],"subject":[],"published":{"date-parts":[[1998,5]]}}}