{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T14:33:25Z","timestamp":1791297205746,"version":"4.1.0"},"reference-count":31,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[1998,7,1]],"date-time":"1998-07-01T00:00:00Z","timestamp":899251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[1998,7,1]],"date-time":"1998-07-01T00:00:00Z","timestamp":899251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":5495,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Virology"],"published-print":{"date-parts":[[1998,7]]},"DOI":"10.1006\/viro.1998.9200","type":"journal-article","created":{"date-parts":[[2002,10,6]],"date-time":"2002-10-06T19:24:08Z","timestamp":1033932248000},"page":"317-328","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":251,"title":["Monoclonal Antibody Mapping of the Envelope Glycoprotein of the Dengue 2 Virus, Jamaica"],"prefix":"10.1006","volume":"246","author":[{"given":"John T.","family":"Roehrig","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard A.","family":"Bolin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert G.","family":"Kelly","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1006\/viro.1998.9200_VY989200RF1","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1007\/BF01311358","article-title":"Serologically defined linear epitopes in the envelope protein of dengue-2 (Jamaica strain 1409)","volume":"105","author":"Aaskov","year":"1989","journal-title":"Arch. Virol."},{"key":"10.1006\/viro.1998.9200_VY989200RF2","doi-asserted-by":"crossref","first-page":"548","DOI":"10.4269\/ajtmh.1982.31.548","article-title":"Identification of distinct antigenic determinants on dengue-2 virus using monoclonal antibodies","volume":"31","author":"Gentry","year":"1982","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1006\/viro.1998.9200_VY989200RF3","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1038\/321244a0","article-title":"A new mechanism for the neutralization of enveloped viruses by antiviral antibody","volume":"321","author":"Gollins","year":"1986","journal-title":"Nature (London)"},{"key":"10.1006\/viro.1998.9200_VY989200RF4","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1016\/0042-6822(92)90267-S","article-title":"The Murray Valley encephalitis virus prM protein confers acid resistance to virus particles and alters the expression of epitopes within the R2 domain of the E glycoprotein","volume":"191","author":"Guirakhoo","year":"1992","journal-title":"Virology"},{"key":"10.1006\/viro.1998.9200_VY989200RF5","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/0042-6822(89)90044-5","article-title":"Epitope model of tick-borne encephalitis virus envelope glycoprotein E: Analysis of structural properties, role of carbohydrate, and conformational changes occurring at acidic pH","volume":"169","author":"Guirakhoo","year":"1989","journal-title":"Virology"},{"key":"10.1006\/viro.1998.9200_VY989200RF6","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1006\/viro.1993.1252","article-title":"Selection and partial characterization of dengue 2 virus mutants that induce fusion at elevated pH","volume":"194","author":"Guirakhoo","year":"1993","journal-title":"Virology"},{"key":"10.1006\/viro.1998.9200_VY989200RF7","series-title":"Immunochemistry of Viruses. II. The Basis for Serodiagnosis and Vaccines","article-title":"Flaviviruses","author":"Heinz","year":"1990"},{"key":"10.1006\/viro.1998.9200_VY989200RF8","doi-asserted-by":"crossref","first-page":"162","DOI":"10.4269\/ajtmh.1985.34.162","article-title":"Epitopic analysis of antigenic determinants on the surface of dengue-2 virions using monoclonal antibodies","volume":"34","author":"Henchal","year":"1985","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1006\/viro.1998.9200_VY989200RF9","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1006\/viro.1996.0550","article-title":"Mutational analysis of a neutralization epitope on the dengue type 2 virus (DEN2) envelope protein: Monoclonal antibody resistant DEN2\/DEN4 chimeras exhibit reduced mouse neurovirulence","volume":"224","author":"Hiramatsu","year":"1996","journal-title":"Virology"},{"key":"10.1006\/viro.1998.9200_VY989200RF10","doi-asserted-by":"crossref","first-page":"676","DOI":"10.4269\/ajtmh.1989.40.676","article-title":"Identification of continuous epitopes of the envelope glycoprotein of dengue type 2 virus","volume":"40","author":"Innis","year":"1989","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1006\/viro.1998.9200_VY989200RF11","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1007\/BF01314966","article-title":"Analysis of functional epitopes on the dengue 2 envelope (E) protein using monoclonal IgM antibodies","volume":"140","author":"Jainmin","year":"1995","journal-title":"Arch. Virol."},{"key":"10.1006\/viro.1998.9200_VY989200RF12","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1006\/viro.1994.1481","article-title":"The envelope glycoproteins of dengue 1 and dengue 2 viruses grown in mosquito cells differ in their utilization of potential glycosylation sites","volume":"203","author":"Johnson","year":"1994","journal-title":"Virology"},{"key":"10.1006\/viro.1998.9200_VY989200RF13","doi-asserted-by":"crossref","first-page":"427","DOI":"10.4269\/ajtmh.1987.36.427","article-title":"Monoclonal antibodies against dengue 2 virus E-glycoprotein protect mice against lethal dengue infection","volume":"36","author":"Kaufman","year":"1987","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1006\/viro.1998.9200_VY989200RF14","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","article-title":"Cleavage of structural proteins during the assembly of the head of bacteriophage T4","volume":"277","author":"Laemmli","year":"1970","journal-title":"Nature (London)"},{"key":"10.1006\/viro.1998.9200_VY989200RF15","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1006\/viro.1994.1410","article-title":"Localization of a neutralizing epitope on the envelope protein of dengue virus type 2","volume":"202","author":"Lin","year":"1994","journal-title":"Virology"},{"key":"10.1006\/viro.1998.9200_VY989200RF16","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1128\/jvi.63.2.564-571.1989","article-title":"Antigenic structure of the flavivirus envelope protein E at the molecular level, using tick-borne encephalitis virus as a model","volume":"63","author":"Mandl","year":"1989","journal-title":"J. Virol."},{"key":"10.1006\/viro.1998.9200_VY989200RF17","doi-asserted-by":"crossref","first-page":"2037","DOI":"10.1099\/0022-1317-70-8-2037","article-title":"Molecular characterization of a neutralizing domain of the Japanese encephalitis virus structural glycoprotein","volume":"70","author":"Mason","year":"1989","journal-title":"J. Gen. Virol."},{"key":"10.1006\/viro.1998.9200_VY989200RF18","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/0042-6822(92)90450-4","article-title":"Use of recombinant fusion proteins and monoclonal antibodies to define linear and discontinuous antigenic sites on the dengue virus envelope glycoprotein","volume":"187","author":"Megret","year":"1992","journal-title":"Virology"},{"key":"10.1006\/viro.1998.9200_VY989200RF19","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1099\/0022-1317-67-4-639","article-title":"Multisite monoclonal immunoassay for dengue viruses: Detection of viraemic human sera and interference by heterologous antibody","volume":"67","author":"Monath","year":"1986","journal-title":"J. Gen. Virol."},{"key":"10.1006\/viro.1998.9200_VY989200RF20","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1099\/0022-1317-22-1-21","article-title":"Comparative electrophoretic analysis of the virus proteins of four rhabdoviruses","volume":"22","author":"Obijeski","year":"1974","journal-title":"J. Gen. Virol."},{"key":"10.1006\/viro.1998.9200_VY989200RF21","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1038\/375291a0","article-title":"The envelope glycoprotein from tick-borne encephalitis virus at 2 \u00c5 resolution","volume":"375","author":"Rey","year":"1995","journal-title":"Nature"},{"key":"10.1006\/viro.1998.9200_VY989200RF22","series-title":"Dengue and Dengue Hemorraghic Fever","first-page":"199","article-title":"Immunochemistry of dengue viruses","author":"Roehrig","year":"1997"},{"key":"10.1006\/viro.1998.9200_VY989200RF23","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/0042-6822(80)90481-X","article-title":"Isolation and characterization of hybrid cell lines producing monoclonal antibodies directed against the structural proteins of Sindbis virus","volume":"101","author":"Roehrig","year":"1980","journal-title":"Virology"},{"key":"10.1006\/viro.1998.9200_VY989200RF24","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/0042-6822(82)90346-4","article-title":"Antigenic analysis of the surface glycoproteins of a Venezuelan equine encephalomyelitis virus (TC-83) using monoclonal antibodies","volume":"118","author":"Roehrig","year":"1982","journal-title":"Virology"},{"key":"10.1006\/viro.1998.9200_VY989200RF25","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/0042-6822(83)90323-9","article-title":"Identification of epitopes on the E glycoprotein of Saint Louis encephalitis virus using monoclonal antibodies","volume":"128","author":"Roehrig","year":"1983","journal-title":"Virology"},{"key":"10.1006\/viro.1998.9200_VY989200RF26","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/0042-6822(85)90343-5","article-title":"The neutralization site on the E2 glycoprotein of Venezuelan equine encephalomyelitis (TC-83) virus is composed of multiple conformationally stable epitopes","volume":"142","author":"Roehrig","year":"1985","journal-title":"Virology"},{"key":"10.1006\/viro.1998.9200_VY989200RF27","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1016\/0042-6822(90)90532-V","article-title":"Antibodies to dengue 2 virus E-glycoprotein synthetic peptides identify antigenic conformation","volume":"177","author":"Roehrig","year":"1990","journal-title":"Virology"},{"key":"10.1006\/viro.1998.9200_VY989200RF28","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1006\/viro.1994.1005","article-title":"T-helper cell epitopes on the E-glycoprotein of dengue 2 Jamaica virus","volume":"198","author":"Roehrig","year":"1994","journal-title":"Virology"},{"key":"10.1006\/viro.1998.9200_VY989200RF29","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/0022-1759(87)90081-0","article-title":"Purification of monoclonal antibodies from ascites using Abx liquid chromatography column","volume":"102","author":"Ross","year":"1987","journal-title":"J. Immunol. Methods"},{"key":"10.1006\/viro.1998.9200_VY989200RF30","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/0378-1119(92)90509-N","article-title":"Mapping of a region of dengue virus type-2 glycoprotein required for binding by a neutralizing monoclonal antibody","volume":"116","author":"Trirawatanapong","year":"1992","journal-title":"Gene"},{"key":"10.1006\/viro.1998.9200_VY989200RF31","doi-asserted-by":"crossref","first-page":"2239","DOI":"10.1099\/0022-1317-68-8-2239","article-title":"Characterization of a disulphide bridge-stabilized antigenic domain of tick-borne encephalitis virus structural glycoprotein","volume":"68","author":"Winkler","year":"1987","journal-title":"J. Gen. Virol."}],"container-title":["Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682298992005?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682298992005?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T23:01:25Z","timestamp":1758582085000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0042682298992005"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,7]]},"references-count":31,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1998,7]]}},"alternative-id":["S0042682298992005"],"URL":"https:\/\/doi.org\/10.1006\/viro.1998.9200","relation":{},"ISSN":["0042-6822"],"issn-type":[{"value":"0042-6822","type":"print"}],"subject":[],"published":{"date-parts":[[1998,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Monoclonal Antibody Mapping of the Envelope Glycoprotein of the Dengue 2 Virus, Jamaica","name":"articletitle","label":"Article Title"},{"value":"Virology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1006\/viro.1998.9200","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1998 Academic Press. All rights reserved.","name":"copyright","label":"Copyright"}]}}