{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T02:28:28Z","timestamp":1773800908062,"version":"3.50.1"},"reference-count":37,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[1999,5,1]],"date-time":"1999-05-01T00:00:00Z","timestamp":925516800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[1999,5,1]],"date-time":"1999-05-01T00:00:00Z","timestamp":925516800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":5191,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Virology"],"published-print":{"date-parts":[[1999,5]]},"DOI":"10.1006\/viro.1999.9701","type":"journal-article","created":{"date-parts":[[2002,9,19]],"date-time":"2002-09-19T09:00:16Z","timestamp":1032426016000},"page":"189-200","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"title":["Production and Characterization of Human Monoclonal Antibody Fab Fragments to Vaccinia Virus from a Phage-Display Combinatorial Library"],"prefix":"10.1006","volume":"258","author":[{"given":"Connie","family":"Schmaljohn","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yunchang","family":"Cui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen","family":"Kerby","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David","family":"Pennock","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kristin","family":"Spik","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1006\/viro.1999.9701_RF1","doi-asserted-by":"crossref","first-page":"7978","DOI":"10.1073\/pnas.88.18.7978","article-title":"Assembly of combinatorial antibody libraries on phage surfaces: The gene III site","volume":"88","author":"Barbas","year":"1991","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1006\/viro.1999.9701_RF2","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S1046-2023(05)80212-9","article-title":"Combinatorial immunoglobulin libraries on the surface of phage (Phabs): Rapid selection of antigen-specific Fabs","volume":"2","author":"Barbas","year":"1991","journal-title":"Methods: A Companion to Methods in Enzymology"},{"key":"10.1006\/viro.1999.9701_RF3","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1056\/NEJM199808203390811","article-title":"Poxvirus dilemmas\u2013monkeypox, smallpox, and biologic terrorism","volume":"339","author":"Breman","year":"1998","journal-title":"N. Engl. J. Med"},{"key":"10.1006\/viro.1999.9701_RF4","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/0167-7799(91)90055-M","article-title":"Human and mouse monoclonal antibodies by repertoire cloning","volume":"9","author":"Burton","year":"1991","journal-title":"Trends Biotechnol"},{"key":"10.1006\/viro.1999.9701_RF5","first-page":"189","volume":"279","year":"1996","journal-title":"JAMA"},{"key":"10.1006\/viro.1999.9701_RF6","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1016\/0042-6822(87)90481-8","article-title":"A 14K envelope protein of vaccinia virus with an important role in virus-host cell interactions is altered during virus persistence and determines the plaque size phenotype of the virus","volume":"159","author":"Dallo","year":"1987","journal-title":"Virology"},{"key":"10.1006\/viro.1999.9701_RF7","doi-asserted-by":"crossref","first-page":"1538","DOI":"10.1128\/jvi.67.3.1538-1544.1993","article-title":"Vaccinia virus-specific CD8+ cytotoxic T lymphocytes in humans","volume":"67","author":"Demkowicz","year":"1993","journal-title":"J. Virol"},{"key":"10.1006\/viro.1999.9701_RF8","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1128\/jvi.66.1.386-398.1992","article-title":"Identification and characterization of vaccinia virus genes encoding proteins that are highly antigenic in animals and are immunodominant in vaccinated humans","volume":"66","author":"Demkowicz","year":"1992","journal-title":"J. Virol"},{"key":"10.1006\/viro.1999.9701_RF9","doi-asserted-by":"crossref","first-page":"268","DOI":"10.2105\/AJPH.86.2.268","article-title":"A call for the destruction of smallpox virus stores [letter]","volume":"86","author":"Donohoe","year":"1996","journal-title":"Am. J. Public Health"},{"key":"10.1006\/viro.1999.9701_RF10","first-page":"68","article-title":"The efficacy of vaccinia immune globulin. A 15-year study","volume":"31","author":"Feery","year":"1976","journal-title":"Vox Sang"},{"key":"10.1006\/viro.1999.9701_RF11","series-title":"Smallpox and Its Eradication","author":"Fenner","year":"1988"},{"key":"10.1006\/viro.1999.9701_RF12","doi-asserted-by":"crossref","first-page":"154","DOI":"10.3233\/HAB-1993-4401","article-title":"Production methods for generating human monoclonal antibodies","volume":"4","author":"Glassy","year":"1993","journal-title":"Hum. Antibodies Hybridomas"},{"key":"10.1006\/viro.1999.9701_RF13","unstructured":"Harlow, E. Lane, D. 1988, Antibodies A Laboratory Manual, Cold Spring Harbor Laboratory, New York"},{"key":"10.1006\/viro.1999.9701_RF14","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S1380-2933(98)00007-4","article-title":"Antibody phage display technology and its applications","volume":"4","author":"Hoogenboom","year":"1998","journal-title":"Immunotechnology"},{"key":"10.1006\/viro.1999.9701_RF15","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/S0140-6736(05)60158-4","article-title":"Human monkeypox hits beleaguered Zaire [news]","volume":"349","author":"Ivker","year":"1997","journal-title":"Lancet"},{"key":"10.1006\/viro.1999.9701_RF16","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/S1046-2023(05)80211-7","article-title":"Combinational immunoglobulin libraries in phage l","volume":"2","author":"Kang","year":"1991","journal-title":"Methods: A Companion to Methods in Enzymology"},{"key":"10.1006\/viro.1999.9701_RF17","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1001\/archderm.1983.01650290044015","article-title":"Progressive vaccinia associated with combined variable immunodeficiency","volume":"119","author":"Keane","year":"1983","journal-title":"Arch. Dermatol."},{"key":"10.1006\/viro.1999.9701_RF18","doi-asserted-by":"crossref","first-page":"3910","DOI":"10.1128\/jvi.61.12.3910-3919.1987","article-title":"Structural and functional studies of a 39000-Mr","volume":"61","author":"Maa","year":"1987","journal-title":"J. Virol."},{"key":"10.1006\/viro.1999.9701_RF19","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1002\/eji.1830150720","article-title":"Senescence of a human lympho-blastoid clone producing anti-rhesus (D)","volume":"15","author":"Melamed","year":"1985","journal-title":"Eur. J. Immunol."},{"key":"10.1006\/viro.1999.9701_RF20","first-page":"24","volume":"33","year":"1984","journal-title":"Morb. Mortal. Wkly. Rep."},{"key":"10.1006\/viro.1999.9701_RF21","unstructured":"Moss, B. 1990, Poxviridae and their replication, In, Virology, 2, 2079, 2111, Raven Press, New York"},{"key":"10.1006\/viro.1999.9701_RF22","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1016\/S0140-6736(05)63725-7","article-title":"Re-emergence of human monkeypox in Zaire in 1996. Monkeypox Epidemiologic Working Group [letter]","volume":"349","author":"Mukinda","year":"1997","journal-title":"Lancet"},{"key":"10.1006\/viro.1999.9701_RF23","doi-asserted-by":"crossref","first-page":"3550","DOI":"10.1128\/jvi.61.11.3550-3554.1987","article-title":"Mapping and nucleotide sequence of the vaccinia virus gene that encodes a 14-kilodalton fusion protein","volume":"61","author":"Rodriguez","year":"1987","journal-title":"J. Virol."},{"key":"10.1006\/viro.1999.9701_RF24","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1128\/jvi.56.2.482-488.1985","article-title":"Isolation and characterization of neutralizing monoclonal antibodies to vaccinia virus","volume":"56","author":"Rodriguez","year":"1985","journal-title":"J. Virol."},{"key":"10.1006\/viro.1999.9701_RF25","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1128\/jvi.61.2.395-404.1987","article-title":"A 14000-Mr","volume":"61","author":"Rodriguez","year":"1987","journal-title":"J. Virol."},{"key":"10.1006\/viro.1999.9701_RF26","doi-asserted-by":"crossref","first-page":"1821","DOI":"10.1128\/jvi.71.3.1821-1833.1997","article-title":"Characterization of early stages in vaccinia virus membrane biogenesis: Implications of the 21-kilodalton protein and a newly identified 15- kilodalton envelope protein","volume":"71","author":"Rodriguez","year":"1997","journal-title":"J. Virol."},{"key":"10.1006\/viro.1999.9701_RF27","first-page":"215","article-title":"The destruction of smallpox virus stocks in national repositories: A grave mistake and a bad precedent [editorial]","volume":"3","author":"Roizman","year":"1994","journal-title":"Infect. Agents Dis."},{"key":"10.1006\/viro.1999.9701_RF28","doi-asserted-by":"crossref","first-page":"3753","DOI":"10.1128\/jvi.70.6.3753-3762.1996","article-title":"Extracellular vaccinia virus envelope glycoprotein encoded by the A33R gene","volume":"70","author":"Roper","year":"1996","journal-title":"J. Virol."},{"key":"10.1006\/viro.1999.9701_RF29","doi-asserted-by":"crossref","first-page":"7404","DOI":"10.1128\/jvi.71.10.7404-7420.1997","article-title":"Vaccinia virus membrane proteins p8 and p16 are cotranslationally inserted into the rough endoplasmic reticulum and retained in the intermediate compartment","volume":"71","author":"Salmons","year":"1997","journal-title":"J. Virol."},{"key":"10.1006\/viro.1999.9701_RF30","doi-asserted-by":"crossref","first-page":"3162","DOI":"10.1128\/jvi.64.7.3162-3170.1990","article-title":"Antigenic subunits of Hantaan virus expressed by baculovirus and vaccinia virus recombinant","volume":"64","author":"Schmaljohn","year":"1990","journal-title":"J. Virol."},{"key":"10.1006\/viro.1999.9701_RF31","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/0042-6822(87)90310-2","article-title":"Hantaan virus M RNA: Coding strategy, nucleotide sequence, and gene order","volume":"157","author":"Schmaljohn","year":"1987","journal-title":"Virology"},{"key":"10.1006\/viro.1999.9701_RF32","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1016\/0042-6822(86)90309-0","article-title":"Nucleotide sequence of the vaccinia virus hemagglutinin gene","volume":"150","author":"Shida","year":"1986","journal-title":"Virology"},{"key":"10.1006\/viro.1999.9701_RF33","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/BF01315559","article-title":"Fine structure of the vaccinia virus gene encoding the precursor of the major core protein 4 a","volume":"102","author":"Van Meir","year":"1988","journal-title":"Arch. Virol"},{"key":"10.1006\/viro.1999.9701_RF34","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/0042-6822(91)90976-I","article-title":"The multistep proteolytic maturation pathway utilized by vaccinia virus P4a protein: A degenerate conserved cleavage motif within core proteins","volume":"183","author":"Vanslyke","year":"1991","journal-title":"Virology"},{"key":"10.1006\/viro.1999.9701_RF35","doi-asserted-by":"crossref","first-page":"4141","DOI":"10.1073\/pnas.90.9.4141","article-title":"Human monoclonal antibodies against a plethora of viral pathogens from single combinatorial libraries","volume":"90","author":"Williamson","year":"1993","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1006\/viro.1999.9701_RF36","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1006\/viro.1995.1378","article-title":"A myristylated membrane protein encoded by the vaccinia virus L1R open reading frame is the target of potent neutralizing monoclonal antibodies","volume":"211","author":"Wolffe","year":"1995","journal-title":"Virology"},{"key":"10.1006\/viro.1999.9701_RF37","doi-asserted-by":"crossref","first-page":"3175","DOI":"10.1073\/pnas.89.8.3175","article-title":"Human combinatorial antibody libraries to hepatitis B surface antigen","volume":"89","author":"Zebedee","year":"1992","journal-title":"Proc. Natl. Acad. Sci. USA"}],"container-title":["Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682299997015?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682299997015?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T22:57:34Z","timestamp":1758581854000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0042682299997015"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1999,5]]},"references-count":37,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1999,5]]}},"alternative-id":["S0042682299997015"],"URL":"https:\/\/doi.org\/10.1006\/viro.1999.9701","relation":{},"ISSN":["0042-6822"],"issn-type":[{"value":"0042-6822","type":"print"}],"subject":[],"published":{"date-parts":[[1999,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Production and Characterization of Human Monoclonal Antibody Fab Fragments to Vaccinia Virus from a Phage-Display Combinatorial Library","name":"articletitle","label":"Article Title"},{"value":"Virology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1006\/viro.1999.9701","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 1999 Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}