{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T11:47:44Z","timestamp":1762429664644,"version":"3.44.0"},"reference-count":38,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2000,9,1]],"date-time":"2000-09-01T00:00:00Z","timestamp":967766400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2000,9,1]],"date-time":"2000-09-01T00:00:00Z","timestamp":967766400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":4702,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Virology"],"published-print":{"date-parts":[[2000,9]]},"DOI":"10.1006\/viro.2000.0479","type":"journal-article","created":{"date-parts":[[2002,9,19]],"date-time":"2002-09-19T09:00:16Z","timestamp":1032426016000},"page":"255-261","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":31,"title":["Whole Body Positron Emission Tomography Imaging of Activated Lymphoid Tissues during Acute Simian\u2013Human Immunodeficiency Virus 89.6PD Infection in Rhesus Macaques"],"prefix":"10.1006","volume":"274","author":[{"given":"Marianne","family":"Wallace","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Pyzalski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Douglas","family":"Horejsh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles","family":"Brown","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahmoud","family":"Djavani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yichen","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joan M.","family":"Hanson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jacque L.","family":"Mitchen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott B.","family":"Perlman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.David","family":"Pauza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1006\/viro.2000.0479_RF1","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1089\/088922299310304","article-title":"Extracellular HIV type 1 Tat protein induces CD69 expression through NF-\u03baB activation: Possible correlation with cell surface Tat-binding proteins","volume":"15","author":"Bl\u00e1zquez","year":"1999","journal-title":"AIDS Res. Hum. Retroviruses"},{"key":"10.1006\/viro.2000.0479_RF2","series-title":"Pathology of Lymph Nodes","first-page":"81","article-title":"Reactive lymphadenopathies","author":"Chan","year":"1996"},{"key":"10.1006\/viro.2000.0479_RF3","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1056\/NEJM199104043241404","article-title":"High titers of cytopathic virus in plasma of patients with symptomatic primary HIV-1 infection","volume":"324","author":"Clark","year":"1991","journal-title":"N. Engl. J. Med."},{"key":"10.1006\/viro.2000.0479_RF4","doi-asserted-by":"crossref","first-page":"10842","DOI":"10.1073\/pnas.96.19.10842","article-title":"Pronounced acute immunosuppression in vivo mediated by HIV Tat challenge","volume":"96","author":"Cohen","year":"1999","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1006\/viro.2000.0479_RF5","first-page":"814","article-title":"PET in lung cancer","volume":"40","author":"Coleman","year":"1999","journal-title":"J. Nucl. Med."},{"key":"10.1006\/viro.2000.0479_RF6","doi-asserted-by":"crossref","first-page":"10199","DOI":"10.1128\/JVI.73.12.10199-10207.1999","article-title":"Characterization of primary isolate-like variants of simian\u2013human immunodeficiency virus","volume":"73","author":"Crawford","year":"1999","journal-title":"J. Virol."},{"key":"10.1006\/viro.2000.0479_RF7","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1038\/345084a0","article-title":"Tat protein of HIV-1 stimulates growth of cells derived from Kaposi's sarcoma lesions of AIDS patients","volume":"345","author":"Ensoli","year":"1990","journal-title":"Nature"},{"key":"10.1006\/viro.2000.0479_RF8","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1016\/S0092-8674(00)81798-5","article-title":"A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen","volume":"87","author":"Forster","year":"1996","journal-title":"Cell"},{"key":"10.1006\/viro.2000.0479_RF9","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1097\/00042560-199507000-00013","article-title":"Virologic and immunologic characterization of symptomatic and asymptomatic primary HIV-1 infection","volume":"9","author":"Henrard","year":"1995","journal-title":"J. Acquir. Immune Defic. Syndr. Hum. Retrovirol."},{"key":"10.1006\/viro.2000.0479_RF10","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1128\/jvi.69.2.955-967.1995","article-title":"Induction of AIDS by simian immunodeficiency virus from an African green monkey: species-specific variation in pathogenicity correlates with the extent of in vivo replication","volume":"69","author":"Hirsch","year":"1995","journal-title":"J. Virol."},{"key":"10.1006\/viro.2000.0479_RF11","first-page":"567","article-title":"FDG-PET in differentiating lymphoma from nonmalignant central nervous system lesions in patients with AIDS","volume":"34","author":"Hoffman","year":"1993","journal-title":"J. Nucl. Med."},{"key":"10.1006\/viro.2000.0479_RF12","doi-asserted-by":"crossref","first-page":"8952","DOI":"10.1128\/JVI.72.11.8952-8960.1998","article-title":"Tat protein induces human immunodeficiency virus type 1 (HIV-1) coreceptors and promotes infection with both macrophage-tropic and T-lymphotropic HIV-1 strains","volume":"72","author":"Huang","year":"1998","journal-title":"J. Virol."},{"key":"10.1006\/viro.2000.0479_RF13","doi-asserted-by":"crossref","first-page":"2199","DOI":"10.1084\/jem.188.12.2199","article-title":"The critical need for CD4 help in maintaining effective cytotoxic T lymphocyte responses","volume":"188","author":"Kalams","year":"1998","journal-title":"J. Exp. Med."},{"key":"10.1006\/viro.2000.0479_RF14","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1097\/00042560-199809010-00002","article-title":"Rhesus macaques that become systemically infected with pathogenic SHIV 89.6-PD after intravenous, rectal, or vaginal inoculation and fail to make an antiviral antibody response rapidly develop AIDS","volume":"19","author":"Lu","year":"1998","journal-title":"J. Acquir. Immun. Defic. Syndr."},{"key":"10.1006\/viro.2000.0479_RF15","first-page":"431","article-title":"Accuracy of whole-body fluorine-18-FDG PET for the detection of recurrent or metastatic breast carcinoma","volume":"39","author":"Moon","year":"1998","journal-title":"J. Nucl. Med."},{"key":"10.1006\/viro.2000.0479_RF16","doi-asserted-by":"crossref","first-page":"1267","DOI":"10.1056\/NEJM199710303371803","article-title":"Cytotoxic-T-cell responses, viral load, and disease progression in early human immunodeficiency virus type 1 infection","volume":"337","author":"Musey","year":"1997","journal-title":"N. Engl. J. Med."},{"key":"10.1006\/viro.2000.0479_RF17","first-page":"1575","article-title":"PET scanning and the human immunodeficiency virus-positive patient","volume":"38","author":"O'Doherty","year":"1997","journal-title":"J. Nucl. Med."},{"key":"10.1006\/viro.2000.0479_RF18","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1111\/j.1600-065X.1994.tb00867.x","article-title":"Role of lymphoid organs in the pathogenesis of human immunodeficiency virus (HIV) infection","volume":"140","author":"Pantaleo","year":"1994","journal-title":"Immunol. Rev."},{"key":"10.1006\/viro.2000.0479_RF19","first-page":"S83","article-title":"Mucosal transmission of virulent and avirulent lentiviruses in macaques","volume":"14","author":"Pauza","year":"1998","journal-title":"AIDS Res. Hum. Retroviruses"},{"key":"10.1006\/viro.2000.0479_RF20","first-page":"7","article-title":"SIV transmission across the mucosal barrier","volume":"10","author":"Pauza","year":"1994","journal-title":"AIDS Res. Hum. Retroviruses"},{"key":"10.1006\/viro.2000.0479_RF21","doi-asserted-by":"crossref","first-page":"3515","DOI":"10.1073\/pnas.97.7.3515","article-title":"Vaccination with Tat toxoid attenuates disease in simian\/human immunodeficiency virus-challenged macaques","volume":"97","author":"Pauza","year":"2000","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1006\/viro.2000.0479_RF22","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1136\/bmj.299.6692.154","article-title":"Clinical course of primary HIV infection: Consequences for subsequent course of infection","volume":"299","author":"Pedersen","year":"1989","journal-title":"Br. Med. J."},{"key":"10.1006\/viro.2000.0479_RF23","first-page":"81","article-title":"The spectrum of morphologic changes of lymph nodes from patients with AIDS or AIDS-related complex","volume":"37","author":"Racz","year":"1986","journal-title":"Progr. Allergy"},{"key":"10.1006\/viro.2000.0479_RF24","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1126\/science.278.5342.1447","article-title":"Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremia","volume":"278","author":"Rosenberg","year":"1997","journal-title":"Science"},{"key":"10.1006\/viro.2000.0479_RF25","doi-asserted-by":"crossref","first-page":"613","DOI":"10.7326\/0003-4819-128-8-199804150-00001","article-title":"Biological and virologic characteristics of primary HIV infection","volume":"128","author":"Schacker","year":"1998","journal-title":"Ann. Intern. Med."},{"key":"10.1006\/viro.2000.0479_RF26","doi-asserted-by":"crossref","first-page":"6425","DOI":"10.1073\/pnas.93.13.6425","article-title":"Whole body positron emission tomography imaging of simian immunodeficiency virus-infected rhesus macaques","volume":"93","author":"Scharko","year":"1996","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1006\/viro.2000.0479_RF27","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1128\/JVI.73.1.601-607.1999","article-title":"Asymptomatic simian immunodeficiency virus infection decreases blood CD4(+) T cells by accumulating recirculating lymphocytes in the lymphoid tissues","volume":"73","author":"Schenkel","year":"1999","journal-title":"J. Virol."},{"key":"10.1006\/viro.2000.0479_RF28","doi-asserted-by":"crossref","first-page":"2427","DOI":"10.4049\/jimmunol.162.4.2427","article-title":"Extracellular HIV-1 tat protein up-regulates the expression of surface CXC-chemokine receptor 4 in resting CD4+ T cells","volume":"162","author":"Secchiero","year":"1999","journal-title":"J. Immunol."},{"key":"10.1006\/viro.2000.0479_RF29","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1148\/radiographics.19.1.g99ja0761","article-title":"Pitfalls in oncologic diagnosis with FDG PET imaging: Physiologic and benign variants","volume":"19","author":"Shreve","year":"1999","journal-title":"Radiographics"},{"key":"10.1006\/viro.2000.0479_RF30","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1002\/(SICI)1097-0320(19971201)29:4<351::AID-CYTO12>3.0.CO;2-T","article-title":"Lymphocyte subsets and expression of differentiation markers in blood and lymphoid organs of rhesus monkeys","volume":"29","author":"Sopper","year":"1997","journal-title":"Cytometry"},{"key":"10.1006\/viro.2000.0479_RF31","doi-asserted-by":"crossref","first-page":"1600","DOI":"10.1128\/JVI.72.2.1600-1605.1998","article-title":"CD4+-T-cell and CD20+-B-cell changes predict rapid disease progression after simian\u2013human immunodeficiency virus infection in macaques","volume":"72","author":"Steger","year":"1998","journal-title":"J. Virol."},{"key":"10.1006\/viro.2000.0479_RF32","doi-asserted-by":"crossref","first-page":"1853","DOI":"10.1128\/JVI.73.3.1853-1859.1999","article-title":"Acute effects of pathogenic simian\u2013human immunodeficiency virus challenge on vaccine-induced cellular and humoral immune responses to Gag in rhesus macaque","volume":"73","author":"Steger","year":"1999","journal-title":"J. Virol."},{"key":"10.1006\/viro.2000.0479_RF33","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/00002030-199101000-00001","article-title":"Primary HIV infection: host responses and intervention strategies","volume":"5","author":"Tindall","year":"1991","journal-title":"AIDS"},{"key":"10.1006\/viro.2000.0479_RF34","doi-asserted-by":"crossref","first-page":"6876","DOI":"10.1128\/jvi.70.10.6876-6883.1996","article-title":"Intrarectal transmission of simian immunodeficiency virus in rhesus macaques: Selective amplification and host responses to transient or persistent viremia","volume":"70","author":"Trivedi","year":"1996","journal-title":"J. Virol."},{"key":"10.1006\/viro.2000.0479_RF35","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1126\/science.280.5362.427","article-title":"Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection","volume":"280","author":"Veazey","year":"1998","journal-title":"Science"},{"key":"10.1006\/viro.2000.0479_RF36","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1006\/clin.1996.4318","article-title":"Characterization of gut-associated lymphoid tissue (GALT) of normal rhesus macaques","volume":"82","author":"Veazey","year":"1997","journal-title":"Clin. Immunol. Immunopathol."},{"key":"10.1006\/viro.2000.0479_RF37","doi-asserted-by":"crossref","first-page":"10236","DOI":"10.1128\/JVI.73.12.10236-10244.1999","article-title":"Lymphocyte activation during acute simian\/human immunodeficiency virus SHIV89.6PD infection in macaques","volume":"73","author":"Wallace","year":"1999","journal-title":"J. Virol."},{"key":"10.1006\/viro.2000.0479_RF38","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1002\/j.1460-2075.1995.tb07030.x","article-title":"HIV-1 Tat potentiates TNF-induced NF-kappa B activation and cytotoxicity by altering the cellular redox state","volume":"14","author":"Westendorp","year":"1995","journal-title":"EMBO J."}],"container-title":["Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682200904793?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682200904793?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T22:51:29Z","timestamp":1758581489000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0042682200904793"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2000,9]]},"references-count":38,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2000,9]]}},"alternative-id":["S0042682200904793"],"URL":"https:\/\/doi.org\/10.1006\/viro.2000.0479","relation":{},"ISSN":["0042-6822"],"issn-type":[{"type":"print","value":"0042-6822"}],"subject":[],"published":{"date-parts":[[2000,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Whole Body Positron Emission Tomography Imaging of Activated Lymphoid Tissues during Acute Simian\u2013Human Immunodeficiency Virus 89.6PD Infection in Rhesus Macaques","name":"articletitle","label":"Article Title"},{"value":"Virology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1006\/viro.2000.0479","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2000 Academic Press. All rights reserved.","name":"copyright","label":"Copyright"}]}}