{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T02:19:28Z","timestamp":1791425968643,"version":"4.3.3"},"reference-count":23,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2001,11,1]],"date-time":"2001-11-01T00:00:00Z","timestamp":1004572800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2001,11,1]],"date-time":"2001-11-01T00:00:00Z","timestamp":1004572800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2013,7,17]],"date-time":"2013-07-17T00:00:00Z","timestamp":1374019200000},"content-version":"vor","delay-in-days":4276,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Virology"],"published-print":{"date-parts":[[2001,11]]},"DOI":"10.1006\/viro.2001.1168","type":"journal-article","created":{"date-parts":[[2002,9,19]],"date-time":"2002-09-19T09:00:16Z","timestamp":1032426016000},"page":"309-319","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":80,"title":["Phenotypic and Molecular Analyses of Yellow Fever 17DD Vaccine Viruses Associated with Serious Adverse Events in Brazil"],"prefix":"10.1006","volume":"290","author":[{"given":"R.","family":"Galler","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.V.","family":"Pugachev","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.L.S.","family":"Santos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.W.","family":"Ocran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.V.","family":"Jabor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.G.","family":"Rodrigues","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.S.","family":"Marchevsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.S.","family":"Freire","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.F.C.","family":"Almeida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.C.R.","family":"Cruz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.M.Y.","family":"Yamamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"I.M.","family":"Rocco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.S.","family":"Travassos da Rosa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.T.M.","family":"Souza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P.F.C.","family":"Vasconcelos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Guirakhoo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.P.","family":"Monath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1006\/viro.2001.1168_RF1","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/0168-1702(94)00076-O","article-title":"Complete nucleotide sequence of the genome from yellow fever virus 17DD and 17D-213 vaccine strains","volume":"35","author":"Duarte dos Santos","year":"1995","journal-title":"Virus Res."},{"key":"10.1006\/viro.2001.1168_RF2","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1016\/S0264-410X(97)00278-8","article-title":"Genetic variability among yellow fever virus 17D substrains","volume":"16","author":"Galler","year":"1998","journal-title":"Vaccine"},{"key":"10.1006\/viro.2001.1168_RF3","doi-asserted-by":"crossref","first-page":"5477","DOI":"10.1128\/JVI.74.12.5477-5485.2000","article-title":"Recombinant chimeric yellow fever-dengue type 2 virus is immunogenic and protective in nonhuman primates","volume":"74","author":"Guirakhoo","year":"2000","journal-title":"J. Virol."},{"key":"10.1006\/viro.2001.1168_RF4","doi-asserted-by":"crossref","first-page":"20219","DOI":"10.1073\/pnas.84.7.2019","article-title":"Comparison of the virulent Asibi strain of yellow fever virus with the 17D vaccine strain derived from it","volume":"84","author":"Hahn","year":"1987","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1006\/viro.2001.1168_RF5","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1093\/infdis\/169.3.512","article-title":"Analysis of a yellow fever virus isolated from a fatal case of vaccine-associated human encephalitis","volume":"169","author":"Jennings","year":"1994","journal-title":"J. Infect. Dis."},{"key":"10.1006\/viro.2001.1168_RF6","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1016\/S0092-1157(87)80003-3","article-title":"The monkey safety test for neurovirulence of YF vaccines: The utility of quantitative clinical evaluation and histological examination","volume":"15","author":"Levenbook","year":"1987","journal-title":"J. Biol. Stand."},{"key":"10.1006\/viro.2001.1168_RF7","doi-asserted-by":"crossref","first-page":"75","DOI":"10.4269\/ajtmh.1995.52.75","article-title":"Phenotypic analysis of yellow fever virus derived from complementary DNA","volume":"52","author":"Marchevsky","year":"1995","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1006\/viro.2001.1168_RF8","unstructured":"Monath, T. P.1999. Yellow fever. InVaccines (S. Plotkin and W. Orenstein, Eds.), pp. 815\u2013998. Saunders, Philadelphia."},{"key":"10.1006\/viro.2001.1168_RF9","doi-asserted-by":"crossref","first-page":"1742","DOI":"10.1128\/JVI.74.4.1742-1751.2000","article-title":"Chimeric yellow fever 17D-Japanese encephalitis virus vaccine: Dose\u2013response effectiveness and extended safety testing in rhesus monkeys","volume":"74","author":"Monath","year":"2000","journal-title":"J. Virol."},{"key":"10.1006\/viro.2001.1168_RF10","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1006\/viro.1997.8956","article-title":"Attenuation of Japanese encephalitis virus by selection of its mouse brain membrane receptor preparation escape variants","volume":"241","author":"Ni","year":"1998","journal-title":"Virology"},{"key":"10.1006\/viro.2001.1168_RF11","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/0042-6822(92)90745-B","article-title":"Heterogeneity in envelope protein sequence and N-linked glycosylation among yellow fever virus vaccine strains","volume":"188","author":"Post","year":"1992","journal-title":"Virology"},{"key":"10.1006\/viro.2001.1168_RF12","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1126\/science.4023707","article-title":"Nucleotide sequence of yellow fever virus: Implications for flavivirus gene expression and evolution","volume":"229","author":"Rice","year":"1985","journal-title":"Science"},{"key":"10.1006\/viro.2001.1168_RF13","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1001\/jama.1996.03540140045025","article-title":"Yellow fever: A decade of reemergence","volume":"276","author":"Robertson","year":"1996","journal-title":"J. Am. Med. Assoc."},{"key":"10.1006\/viro.2001.1168_RF14","doi-asserted-by":"crossref","first-page":"6278","DOI":"10.1128\/jvi.70.9.6278-6287.1996","article-title":"Cell proteins bind specifically to West Nile virus minus-strand 3\u2032 stem\u2013loop RNA","volume":"70","author":"Shi","year":"1986","journal-title":"J. Virol."},{"key":"10.1006\/viro.2001.1168_RF15","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1016\/S0264-410X(98)00320-X","article-title":"Recent immunization against measles does not interfere with the seroresponse to yellow fever vaccine","volume":"17","author":"Stefano","year":"1999","journal-title":"Vaccine"},{"key":"10.1006\/viro.2001.1168_RF16","doi-asserted-by":"crossref","first-page":"298","DOI":"10.3201\/eid0603.000311","article-title":"Dengue epidemic in Bel\u00e9m, Par\u00e1, Brazil, 1996\u201397","volume":"6","author":"Travassos da Rosa","year":"2000","journal-title":"Emerging Infect. Dis."},{"key":"10.1006\/viro.2001.1168_RF17","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1006\/viro.1996.0508","article-title":"Fatal Sindbis virus infection of neonatal mice in the absence of encephalitis","volume":"224","author":"Trgovcich","year":"1996","journal-title":"Virology"},{"key":"10.1006\/viro.2001.1168_RF18","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1006\/viro.1996.8289","article-title":"Sindbis virus infection of neonatal mice results in a severe stress response","volume":"227","author":"Trgovcich","year":"1997","journal-title":"Virology"},{"key":"10.1006\/viro.2001.1168_RF19","doi-asserted-by":"crossref","first-page":"132","DOI":"10.4269\/ajtmh.1997.57.132","article-title":"An epidemic of sylvatic yellow fever in the southeast region of Maranhao State, Brazil, 1993\u20131994: Epidemiologic and entomologic findings","volume":"57","author":"Vasconcelos","year":"1997","journal-title":"Am. J. Trop. Med. Hyg."},{"key":"10.1006\/viro.2001.1168_RF20","first-page":"55","article-title":"Aedes aegypti, dengue and re-urbanization of yellow fever in Brazil and other South American countries. Past and present, and future perspectives","volume":"23","author":"Vasconcelos","year":"1999","journal-title":"WHO Dengue Bull."},{"key":"10.1006\/viro.2001.1168_RF21","doi-asserted-by":"crossref","DOI":"10.1002\/jmv.2078","article-title":"An epidemic of jungle yellow fever in Brazil, 2000: Implications of climatic alterations on disease spread","author":"Vasconcelos","year":"2001","journal-title":"J. Med. Virol."},{"key":"10.1006\/viro.2001.1168_RF22","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0140-6736(01)05326-0","article-title":"Serious adverse events associated with yellow fever 17DD vaccine in Brazil: Report of two cases","volume":"358","author":"Vasconcelos","year":"2001","journal-title":"Lancet"},{"key":"10.1006\/viro.2001.1168_RF23","unstructured":"World Health Organization (WHO)1995. Expert Committee on Biological Standardization, requirements for yellow fever vaccine. WHO Tech. Rep. Ser. 1\u201354."}],"container-title":["Virology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682201911687?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0042682201911687?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T22:42:50Z","timestamp":1758580970000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0042682201911687"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2001,11]]},"references-count":23,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2001,11]]}},"alternative-id":["S0042682201911687"],"URL":"https:\/\/doi.org\/10.1006\/viro.2001.1168","relation":{},"ISSN":["0042-6822"],"issn-type":[{"value":"0042-6822","type":"print"}],"subject":[],"published":{"date-parts":[[2001,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Phenotypic and Molecular Analyses of Yellow Fever 17DD Vaccine Viruses Associated with Serious Adverse Events in Brazil","name":"articletitle","label":"Article Title"},{"value":"Virology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1006\/viro.2001.1168","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"converted-article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2001 Elsevier Science (USA). All rights reserved.","name":"copyright","label":"Copyright"}]}}