{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T20:05:52Z","timestamp":1760645152263},"publisher-location":"Boston, MA","reference-count":33,"publisher":"Springer US","isbn-type":[{"type":"print","value":"9780306463679"},{"type":"electronic","value":"9780306468254"}],"license":[{"start":{"date-parts":[[2002,1,1]],"date-time":"2002-01-01T00:00:00Z","timestamp":1009843200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2002]]},"DOI":"10.1007\/0-306-46825-5_32","type":"book-chapter","created":{"date-parts":[[2006,3,5]],"date-time":"2006-03-05T23:26:54Z","timestamp":1141601214000},"page":"349-357","source":"Crossref","is-referenced-by-count":5,"title":["Carotid Body Gap Junctions: Secretion of Transmitters and Possible Electric Coupling Between Glomus Cells and Nerve Terminals"],"prefix":"10.1007","author":[{"given":"C.","family":"Eyzaguirre","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"32_CR1","doi-asserted-by":"crossref","unstructured":"Abbott, NJ. (ed), 1991, Glial-Neuronal Interactions. N.Y. Acad. Sci., vol. 633.","DOI":"10.1111\/j.1749-6632.1991.tb15588.x"},{"key":"32_CR2","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/S0006-8993(98)00127-9","volume":"792","author":"V. Abudara","year":"1998","unstructured":"Abudara, V., and Eyzaguirre, C., 1998, Modulation of junctional conductance between rat carotid body glomus cells by hypoxia, cAMP and acidity. Brain Res. 792: 114\u2013125.","journal-title":"Brain Res."},{"key":"32_CR3","doi-asserted-by":"crossref","unstructured":"Abudara, V., Garc\u00e9s, G., and S\u00e1ez, J.C., 1999, Cells of the carotid body express connexin43, which is upregulated by cAMP. Brain Res. (submitted).","DOI":"10.1016\/S0006-8993(99)01946-0"},{"key":"32_CR4","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/0006-8993(90)90133-V","volume":"534","author":"J. Alcayage","year":"1990","unstructured":"Alcayage, J., and Eyzaguirre, C., 1990, Electrophysiological evidence for the reconstitution of chemosensory units in co-cultures of carotid body and nodose ganglion neurons. Brain Res. 534: 234\u2013328.","journal-title":"Brain Res."},{"key":"32_CR5","unstructured":"Bennett, M.V.L., and Spray, D.C. (eds.), 1985, Gap Junctions. Cold Spring Harbor Laboratory."},{"key":"32_CR6","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1152\/physrev.1971.51.3.646-r","volume":"51","author":"T.J. Biscoe","year":"1971","unstructured":"Biscoe, T.J., 1971, Carotid body: Structure and function. Physiol. Rev. 51: 421\u2013495.","journal-title":"Physiol. Rev."},{"key":"32_CR7","first-page":"331","volume":"25","author":"F. Castro","year":"1928","unstructured":"De Castro, F., 1928, Sur la structure et l\u2019innervation du sinus carotidien de l\u2019homme et des mammif\u00e8res. Nouveaux faits sur l\u2019innervation et la fonction du glomus caroticum. \u00c9tudes anatomiques et physiologiques. Trab. Lab. Invest. Biol. Univ. Madrid 25: 331\u2013380.","journal-title":"Trab. Lab. Invest. Biol. Univ. Madrid"},{"key":"32_CR8","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1159\/000140922","volume":"21","author":"L.L. Koch","year":"1954","unstructured":"De Koch, L.L., 1954, The intraglomerular tissue of the carotid body. Acta. Anat. 21: 101\u2013116.","journal-title":"Acta. Anat."},{"key":"32_CR9","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1038\/325060a0","volume":"325","author":"K. Dunlap","year":"1987","unstructured":"Dunlap, K., Takeda, K., and Brehm, P., 1987, Activation of a calcium-dependent photoprotein by chemical signalling through gap junctions. Nature 325: 60\u201362.","journal-title":"Nature"},{"key":"32_CR10","unstructured":"Eyzaguirre, C., and Gallego, A., 1975, An examination of de Castro\u2019s original slides. In The Peripheral Arterial Chemoreceptors (M.J. Purves, ed.), Cambridge University Press, pp. 1\u201323."},{"key":"32_CR11","first-page":"219","volume":"15","author":"C. Eyzaguirre","year":"1982","unstructured":"Eyzaguirre, C., and Zapata, P., 1982, Trophic interactions between sensory nerves and their preneural elements. Arch. Biol. Med. Exper. 15: 219\u2013228.","journal-title":"Arch. Biol. Med. Exper."},{"key":"32_CR12","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1152\/jappl.1984.57.4.931","volume":"57","author":"C. Eyzaguirre","year":"1984","unstructured":"Eyzaguirre, C., and Zapata, P., 1984, Perspectives in carotid body research. J. Appl. Physiol. 57: 931\u2013957.","journal-title":"J. Appl. Physiol."},{"key":"32_CR13","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1159\/000109451","volume":"4","author":"C. Eyzaguirre","year":"1995","unstructured":"Eyzaguirre, C., and Abudara, V.,1995, Possible role of coupling between glomus cells in carotid body chemoreception. Biol. Signals 4: 263\u2013270.","journal-title":"Biol. Signals"},{"key":"32_CR14","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1007\/978-1-4615-5891-0_23","volume":"410","author":"C. Eyzaguirre","year":"1996","unstructured":"Eyzaguirre, C., and Abudara, V., 1996, Reflections on the carotid nerve sensory discharge and coupling between glomus cells. Adv. Exp. Med. Biol. 410: 159\u2013168.","journal-title":"Adv. Exp. Med. Biol."},{"key":"32_CR15","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S0034-5687(99)00020-1","volume":"115","author":"C. Eyzaguirre","year":"1999","unstructured":"Eyzaguirre, C.,and Abudara, V., 1999, Carotid body glomus cells: chemicalsecretion and transmission (modulation?) across cell-nerve ending junctions. Resp. Physiol. 115: 135\u2013149.","journal-title":"Resp. Physiol."},{"key":"32_CR16","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1152\/jn.1980.44.6.1077","volume":"44","author":"Y. Hayashida","year":"1980","unstructured":"Hayashida, Y., Koyano, H., and Eyzaguirre, C., 1980, An intracellular study of chemosensory fibers and endings. J. Neurophysiol. 44: 1077\u20131088.","journal-title":"J. Neurophysiol."},{"key":"32_CR17","first-page":"1365","volume":"31","author":"A. Hess","year":"1972","unstructured":"Hess, A., and Zapata, P., 1972, Innervation of the cat carotid body: normal and experimental studies. Fed. Proc. 31: 1365\u20131382.","journal-title":"Fed. Proc."},{"key":"32_CR18","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1007\/BF00210887","volume":"227","author":"H. Kondo","year":"1982","unstructured":"Kondo, H., Iwanga, T., and Nakajima, T., 1982, Immunocytochemical study on the localization of neuron-specific enolase and S-100 protein in the carotid body of rats. Cell Tiss. Res. 227: 291\u2013295.","journal-title":"Cell Tiss. Res."},{"key":"32_CR19","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1007\/978-1-4615-5891-0_4","volume":"410","author":"H. Kondo","year":"1996","unstructured":"Kondo, H., and Iwasa, H., 1996, Re-examination of the carotid body ultrastructure with special attention to the intercellular membrane apposition. Adv. Exp. Med. Biol. 410: 45\u201350.","journal-title":"Adv. Exp. Med. Biol."},{"key":"32_CR20","unstructured":"McDonald, D.M., 1981, Peripheral chemoreceptors: structure-function relationships of the carotid body. In Lung Biology in Health and Disease. Regulation of Breathing, vol. 17 (T.F. Hornbein and C. Lenfant, eds.), Marcel Decker, New York, pp. 105\u2013319."},{"key":"32_CR21","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/0006-8993(83)90793-X","volume":"270","author":"L. Monti-Bloch","year":"1983","unstructured":"Monti-Bloch, L., Stensaas, L.J., and Eyzaguirre, C., 1983, Carotid body grafts induce chemosensitivity in muscle nerve fibers of the cat. Brain Res. 270: 77\u201392.","journal-title":"Brain Res."},{"key":"32_CR22","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/0006-8993(93)90810-A","volume":"622","author":"L. Monti-Bloch","year":"1993","unstructured":"Monti-Bloch, L., Abudara, V., and Eyzaguirre, C., 1993, Electrical communication between glomus cells of the rat carotid body. Brain Res. 622: 119\u2013131.","journal-title":"Brain Res."},{"key":"32_CR23","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/0006-8993(86)90100-9","volume":"381","author":"Y. Oyama","year":"1986","unstructured":"Oyama, Y., Walker, J.W., and Eyzaguirre, C., 1986, Intracellular potassium activity, potassium equilibrium potential and membrane potential of carotid body glomus cells. Brain Res. 381: 405\u2013408.","journal-title":"Brain Res."},{"key":"32_CR24","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/0006-8993(92)90440-K","volume":"575","author":"L. Pang","year":"1992","unstructured":"Pang, L., and Eyzaguirre, C., 1992, Different effects of hypoxia on the membrane potential and input resistance of isolated and clustered carotid body glomus cells. Brain Res. 575: 167\u2013173.","journal-title":"Brain Res."},{"key":"32_CR25","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/0006-8993(93)91453-Y","volume":"623","author":"L. Pang","year":"1993","unstructured":"Pang, L., and Eyzaguirre, C., 1993, Hypoxia affects differently the intracellular pH of clustered and isolated glomus cells of the rat carotid body. Brain Res. 623: 349\u2013355.","journal-title":"Brain Res."},{"key":"32_CR26","unstructured":"Spray, D.C., Scemes, E., and Rozenthal, R., 1999, Cell-cell communication via gap junctions. In Fundamental Neuroscience (M.J. Zigmond, F.E. Bloom, S.C. Landis, J.L. Roberts and L.R. Squire, eds.), Academic Press, New York, pp. 117\u2013343."},{"key":"32_CR27","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1016\/S0074-7696(08)61265-6","volume":"60","author":"V. Verna","year":"1979","unstructured":"Verna, V., 1979, Ultrastructure of the carotid body in the mammals. Int. Rev. Cytol. 60: 271\u2013330.","journal-title":"Int. Rev. Cytol."},{"key":"32_CR28","unstructured":"Verna, A., 1997, The mammalian carotid body: Morphological data. In The Carotid Body Chemoreceptors (C. Gonzalez, ed.), Springer-Landes, Austin, TX, pp. 1\u201329."},{"key":"32_CR29","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/978-1-4615-5891-0_26","volume":"410","author":"N. Weiss","year":"1996","unstructured":"Weiss, N., and Donnelly, D.F., 1996, Depolarization is a critical event in hypoxia-induced glomus cell secretion. Adv. Exp. Med. Biol. 410: 181\u2013187.","journal-title":"Adv. Exp. Med. Biol."},{"key":"32_CR30","unstructured":"Zapata, P., 1982, Arterial chemoreceptors: searching for transmitter and modulator substances. In Trends in Autonomic Pharmacology, vol. 2 (S. Kalsner, ed.), Urban & Schwartzenberg, Baltimore, pp. 343\u2013361."},{"key":"32_CR31","unstructured":"Zapata, P., 1997, Chemosensory activity in the carotid nerve: Effects of physiological variables. In The Carotid Body Chemoreceptors (C. Gonzalez, ed.), Springer-Landes, Austin, TX, pp. 97\u2013117."},{"key":"32_CR32","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/0006-8993(95)00158-M","volume":"676","author":"X.Q. Zhang","year":"1995","unstructured":"Zhang, X.Q., Pang, L., and Eyzaguirre, C., 1995, Effects of hypoxia on the intracellular K+ of clustered and isolated glomus cells of mice and rats. Brain Res. 676: 413\u2013420.","journal-title":"Brain Res."},{"key":"32_CR33","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1111\/j.1469-7793.1997.599bg.x","volume":"503","author":"H. Zhong","year":"1997","unstructured":"Zhong, H., Zhang, M., and Nurse, C.A., 1997, Synapse formation and hypoxic signalling in co-cultures of rat petrosal neurones and carotid body type I cells. J. Physiol., London 503: 599\u2013612.","journal-title":"J. Physiol., London"}],"container-title":["Advances in Experimental Medicine and Biology","Oxygen Sensing"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/0-306-46825-5_32","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,1,29]],"date-time":"2020-01-29T17:42:20Z","timestamp":1580319740000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/0-306-46825-5_32"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002]]},"ISBN":["9780306463679","9780306468254"],"references-count":33,"URL":"https:\/\/doi.org\/10.1007\/0-306-46825-5_32","relation":{},"ISSN":["0065-2598"],"issn-type":[{"type":"print","value":"0065-2598"}],"subject":[],"published":{"date-parts":[[2002]]}}}