{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T20:50:37Z","timestamp":1791492637924,"version":"4.3.4"},"publisher-location":"Berlin, Heidelberg","reference-count":93,"publisher":"Springer Berlin Heidelberg","content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026]]},"DOI":"10.1007\/10_2026_337","type":"book-chapter","created":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T20:28:22Z","timestamp":1791491302000},"update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Advances in Bioproduction of Feed Amino Acids in China"],"prefix":"10.1007","author":[{"given":"Liu","family":"Jingui","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wang","family":"Lintao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han","family":"Xuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shi","family":"Xinlei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wu","family":"Heyun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ma","family":"Qian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xie","family":"Xixian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2026,10,9]]},"reference":[{"issue":"5","key":"337_CR1","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1007\/BF00243503","volume":"65","author":"F Schena","year":"1992","unstructured":"Schena F et al (1992) Branched-chain amino acid supplementation during trekking at high altitude. The effects on loss of body mass, body composition, and muscle power. Eur J Appl Physiol Occup Physiol 65(5):394\u2013398","journal-title":"Eur J Appl Physiol Occup Physiol"},{"key":"337_CR2","doi-asserted-by":"crossref","DOI":"10.3389\/fvets.2021.689259","volume":"8","author":"L Cappelaere","year":"2021","unstructured":"Cappelaere L et al (2021) Amino acid supplementation to reduce environmental impacts of broiler and pig production: a review. Front Vet Sci 8:689259","journal-title":"Front Vet Sci"},{"issue":"1","key":"337_CR3","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/s40104-022-00676-5","volume":"13","author":"C Tan","year":"2022","unstructured":"Tan C et al (2022) A review of the amino acid metabolism in placental function response to fetal loss and low birth weight in pigs. J Anim Sci Biotechnol 13(1):28","journal-title":"J Anim Sci Biotechnol"},{"key":"337_CR4","doi-asserted-by":"crossref","first-page":"1253178","DOI":"10.3389\/fpls.2023.1253178","volume":"14","author":"Z Du","year":"2023","unstructured":"Du Z et al (2023) Silage preparation and sustainable livestock production of natural woody plant. Front Plant Sci 14:1253178","journal-title":"Front Plant Sci"},{"issue":"3","key":"337_CR5","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1053\/j.jrn.2013.01.030","volume":"23","author":"L Garneata","year":"2013","unstructured":"Garneata L, Mircescu G (2013) Effect of low-protein diet supplemented with keto acids on progression of chronic kidney disease. J Ren Nutr 23(3):210\u2013213","journal-title":"J Ren Nutr"},{"issue":"4","key":"337_CR6","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1080\/1745039X.2019.1614849","volume":"73","author":"D Yu","year":"2019","unstructured":"Yu D, Zhu W, Hang S (2019) Effects of low-protein diet on the intestinal morphology, digestive enzyme activity, blood urea nitrogen, and gut microbiota and metabolites in weaned pigs. Arch Anim Nutr 73(4):287\u2013305","journal-title":"Arch Anim Nutr"},{"issue":"1","key":"337_CR7","volume":"96","author":"H Do","year":"2025","unstructured":"Do H et al (2025) Plasma free amino acid profiles during fattening period predict carcass traits in female Japanese Black Cattle: a preliminary study. Anim Sci J 96(1):e70137","journal-title":"Anim Sci J"},{"key":"337_CR8","first-page":"1","volume":"79","author":"M Ikeda","year":"2003","unstructured":"Ikeda M (2003) Amino acid production processes. Adv Biochem Eng Biotechnol 79:1\u201335","journal-title":"Adv Biochem Eng Biotechnol"},{"issue":"3","key":"337_CR9","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1128\/jb.138.3.933-943.1979","volume":"138","author":"B Ely","year":"1979","unstructured":"Ely B, Pittard J (1979) Aromatic amino acid biosynthesis: regulation of shikimate kinase in Escherichia coli K-12. J Bacteriol 138(3):933\u2013943","journal-title":"J Bacteriol"},{"issue":"3","key":"337_CR10","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/s11274-021-03007-4","volume":"37","author":"Y Tsuge","year":"2021","unstructured":"Tsuge Y, Matsuzawa H (2021) Recent progress in production of amino acid-derived chemicals using Corynebacterium glutamicum. World J Microbiol Biotechnol 37(3):49","journal-title":"World J Microbiol Biotechnol"},{"key":"337_CR11","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1007\/978-1-0716-2233-9_13","volume":"2479","author":"Z Wen","year":"2022","unstructured":"Wen Z et al (2022) Genome editing of Corynebacterium glutamicum using CRISPR-Cpf1 system. Methods Mol Biol 2479:189\u2013206","journal-title":"Methods Mol Biol"},{"key":"337_CR12","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.ymben.2015.06.006","volume":"31","author":"Y Li","year":"2015","unstructured":"Li Y et al (2015) Metabolic engineering of Escherichia coli using CRISPR-Cas9 meditated genome editing. Metab Eng 31:13\u201321","journal-title":"Metab Eng"},{"issue":"1","key":"337_CR13","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1080\/03079457.2010.539590","volume":"40","author":"M Emadi","year":"2011","unstructured":"Emadi M et al (2011) Nutrition and immunity: the effects of the combination of arginine and tryptophan on growth performance, serum parameters and immune response in broiler chickens challenged with infectious bursal disease vaccine. Avian Pathol 40(1):63\u201372","journal-title":"Avian Pathol"},{"issue":"1","key":"337_CR14","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.domaniend.2006.04.005","volume":"33","author":"H Zhang","year":"2007","unstructured":"Zhang H et al (2007) Tryptophan enhances ghrelin expression and secretion associated with increased food intake and weight gain in weanling pigs. Domest Anim Endocrinol 33(1):47\u201361","journal-title":"Domest Anim Endocrinol"},{"key":"337_CR15","volume":"156","author":"S Moi","year":"2022","unstructured":"Moi S et al (2022) Significance of D-tryptophan in Contryphan-Ar1131 Conus peptide: oxidative folding, trypsin binding, and photostabilization activity. Peptides 156:170845","journal-title":"Peptides"},{"issue":"9","key":"337_CR16","doi-asserted-by":"crossref","first-page":"1846","DOI":"10.1016\/j.cell.2023.03.011","volume":"186","author":"MJ Bender","year":"2023","unstructured":"Bender MJ et al (2023) Dietary tryptophan metabolite released by intratumoral Lactobacillus reuteri facilitates immune checkpoint inhibitor treatment. Cell 186(9):1846\u20131862.e26","journal-title":"Cell"},{"issue":"2","key":"337_CR17","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.immuni.2022.01.006","volume":"55","author":"K Hezaveh","year":"2022","unstructured":"Hezaveh K et al (2022) Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity. Immunity 55(2):324\u2013340.e8","journal-title":"Immunity"},{"issue":"8","key":"337_CR18","doi-asserted-by":"crossref","first-page":"2765","DOI":"10.1021\/ja01188a038","volume":"70","author":"DT Warner","year":"1948","unstructured":"Warner DT, Moe OA (1948) Amino acids; new syntheses of DL-tryptophan, DL-ornithine and DL-glutamic acid. J Am Chem Soc 70(8):2765\u20132767","journal-title":"J Am Chem Soc"},{"key":"337_CR19","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.ymben.2019.03.008","volume":"58","author":"VF Wendisch","year":"2020","unstructured":"Wendisch VF (2020) Metabolic engineering advances and prospects for amino acid production. Metab Eng 58:17\u201334","journal-title":"Metab Eng"},{"key":"337_CR20","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1186\/1475-2859-11-30","volume":"11","author":"P Gu","year":"2012","unstructured":"Gu P et al (2012) One-step of tryptophan attenuator inactivation and promoter swapping to improve the production of L-tryptophan in Escherichia coli. Microb Cell Factories 11:30","journal-title":"Microb Cell Factories"},{"issue":"2","key":"337_CR21","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.mib.2008.02.005","volume":"11","author":"E Merino","year":"2008","unstructured":"Merino E, Jensen RA, Yanofsky C (2008) Evolution of bacterial trp operons and their regulation. Curr Opin Microbiol 11(2):78\u201386","journal-title":"Curr Opin Microbiol"},{"key":"337_CR22","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.3389\/fmicb.2015.01310","volume":"6","author":"J Kuepper","year":"2015","unstructured":"Kuepper J et al (2015) Metabolic engineering of Pseudomonas putida KT2440 to produce anthranilate from glucose. Front Microbiol 6:1310","journal-title":"Front Microbiol"},{"issue":"21","key":"337_CR23","doi-asserted-by":"crossref","first-page":"6389","DOI":"10.1128\/jb.178.21.6389-6393.1996","volume":"178","author":"J Yang","year":"1996","unstructured":"Yang J, Camakaris H, Pittard AJ (1996) In vitro transcriptional analysis of TyrR-mediated activation of the mtr and tyrP+3 promoters of Escherichia coli. J Bacteriol 178(21):6389\u20136393","journal-title":"J Bacteriol"},{"issue":"Pt 2","key":"337_CR24","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1099\/mic.0.064139-0","volume":"159","author":"G Li","year":"2013","unstructured":"Li G, Young KD (2013) Indole production by the tryptophanase TnaA in Escherichia coli is determined by the amount of exogenous tryptophan. Microbiology (Reading) 159(Pt 2):402\u2013410","journal-title":"Microbiology (Reading)"},{"issue":"1","key":"337_CR25","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1128\/jb.101.1.202-208.1970","volume":"101","author":"WA Held","year":"1970","unstructured":"Held WA, Smith OH (1970) Regulation of the Escherichia coli tryptophan operon by early reactions in the aromatic pathway. J Bacteriol 101(1):202\u2013208","journal-title":"J Bacteriol"},{"issue":"6","key":"337_CR26","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1007\/s00253-005-0252-y","volume":"69","author":"M Ikeda","year":"2006","unstructured":"Ikeda M (2006) Towards bacterial strains overproducing L-tryptophan and other aromatics by metabolic engineering. Appl Microbiol Biotechnol 69(6):615\u2013626","journal-title":"Appl Microbiol Biotechnol"},{"issue":"12","key":"337_CR27","doi-asserted-by":"crossref","first-page":"1921","DOI":"10.1007\/s10295-011-0978-8","volume":"38","author":"ZJ Zhao","year":"2011","unstructured":"Zhao ZJ et al (2011) Development of L-tryptophan production strains by defined genetic modification in Escherichia coli. J Ind Microbiol Biotechnol 38(12):1921\u20131929","journal-title":"J Ind Microbiol Biotechnol"},{"issue":"5","key":"337_CR28","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1002\/jobm.200310244","volume":"43","author":"C Hu","year":"2003","unstructured":"Hu C et al (2003) Mutation analysis of the feedback inhibition site of phenylalanine-sensitive 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase of Escherichia coli. J Basic Microbiol 43(5):399\u2013406","journal-title":"J Basic Microbiol"},{"key":"337_CR29","volume":"2012","author":"T Shen","year":"2012","unstructured":"Shen T et al (2012) Improved production of tryptophan in genetically engineered Escherichia coli with TktA and PpsA overexpression. J Biomed Biotechnol 2012:605219","journal-title":"J Biomed Biotechnol"},{"issue":"5","key":"337_CR30","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1007\/s10295-018-2020-x","volume":"45","author":"Y Chen","year":"2018","unstructured":"Chen Y et al (2018) Rational design and analysis of an Escherichia coli strain for high-efficiency tryptophan production. J Ind Microbiol Biotechnol 45(5):357\u2013367","journal-title":"J Ind Microbiol Biotechnol"},{"issue":"3","key":"337_CR31","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1002\/bit.28019","volume":"119","author":"L Guo","year":"2022","unstructured":"Guo L et al (2022) Enhancing tryptophan production by balancing precursors in Escherichia coli. Biotechnol Bioeng 119(3):983\u2013993","journal-title":"Biotechnol Bioeng"},{"issue":"1","key":"337_CR32","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1128\/jb.173.1.108-115.1991","volume":"173","author":"VM Heatwole","year":"1991","unstructured":"Heatwole VM, Somerville RL (1991) Cloning, nucleotide sequence, and characterization of mtr, the structural gene for a tryptophan-specific permease of Escherichia coli K-12. J Bacteriol 173(1):108\u2013115","journal-title":"J Bacteriol"},{"issue":"17","key":"337_CR33","doi-asserted-by":"crossref","first-page":"7587","DOI":"10.1007\/s00253-013-5026-3","volume":"97","author":"J Wang","year":"2013","unstructured":"Wang J et al (2013) Genetic engineering of Escherichia coli to enhance production of L-tryptophan. Appl Microbiol Biotechnol 97(17):7587\u20137596","journal-title":"Appl Microbiol Biotechnol"},{"issue":"1","key":"337_CR34","volume":"3","author":"J Tuo","year":"2023","unstructured":"Tuo J et al (2023) Recent advances in screening amino acid overproducers. Eng Microbiol 3(1):100066","journal-title":"Eng Microbiol"},{"key":"337_CR35","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1146\/annurev-physiol-020518-114455","volume":"81","author":"M Neinast","year":"2019","unstructured":"Neinast M, Murashige D, Arany Z (2019) Branched chain amino acids. Annu Rev Physiol 81:139\u2013164","journal-title":"Annu Rev Physiol"},{"issue":"27","key":"337_CR36","doi-asserted-by":"crossref","first-page":"18793","DOI":"10.1074\/jbc.M114.554113","volume":"289","author":"EA Ananieva","year":"2014","unstructured":"Ananieva EA et al (2014) Cytosolic branched chain aminotransferase (BCATc) regulates mTORC1 signaling and glycolytic metabolism in CD4+ T cells. J Biol Chem 289(27):18793\u201318804","journal-title":"J Biol Chem"},{"issue":"2","key":"337_CR37","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/j.ccell.2019.12.011","volume":"37","author":"S Sivanand","year":"2020","unstructured":"Sivanand S, Vander Heiden MG (2020) Emerging roles for branched-chain amino acid metabolism in cancer. Cancer Cell 37(2):147\u2013156","journal-title":"Cancer Cell"},{"key":"337_CR38","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/s40104-016-0139-z","volume":"8","author":"S Zhang","year":"2017","unstructured":"Zhang S et al (2017) Novel metabolic and physiological functions of branched chain amino acids: a review. J Anim Sci Biotechnol 8:10","journal-title":"J Anim Sci Biotechnol"},{"issue":"7","key":"337_CR39","doi-asserted-by":"crossref","first-page":"644","DOI":"10.2174\/1389203720666190305163135","volume":"20","author":"C Gu","year":"2019","unstructured":"Gu C et al (2019) Isoleucine plays an important role for maintaining immune function. Curr Protein Pept Sci 20(7):644\u2013651","journal-title":"Curr Protein Pept Sci"},{"key":"337_CR40","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/j.phrs.2018.05.014","volume":"133","author":"Y Shimomura","year":"2018","unstructured":"Shimomura Y, Kitaura Y (2018) Physiological and pathological roles of branched-chain amino acids in the regulation of protein and energy metabolism and neurological functions. Pharmacol Res 133:215\u2013217","journal-title":"Pharmacol Res"},{"issue":"11","key":"337_CR41","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1021\/sb300071a","volume":"1","author":"JH Park","year":"2012","unstructured":"Park JH et al (2012) Rational design of Escherichia coli for L-isoleucine production. ACS Synth Biol 1(11):532\u2013540","journal-title":"ACS Synth Biol"},{"issue":"13","key":"337_CR42","doi-asserted-by":"crossref","first-page":"2793","DOI":"10.1021\/acs.biochem.5c00168","volume":"64","author":"MK Yun","year":"2025","unstructured":"Yun MK et al (2025) Isoleucine binding and regulation of Escherichia coli and Staphylococcus aureus threonine dehydratase (IlvA). Biochemistry 64(13):2793\u20132810","journal-title":"Biochemistry"},{"issue":"3","key":"337_CR43","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1128\/jb.123.3.862-870.1975","volume":"123","author":"GA Willshaw","year":"1975","unstructured":"Willshaw GA, Tristram H (1975) Inhibition of Escherichia coli isoleucine biosynthesis by isoleucine tetrazole. J Bacteriol 123(3):862\u2013870","journal-title":"J Bacteriol"},{"issue":"4","key":"337_CR44","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1271\/bbb.63.672","volume":"63","author":"K Hashiguchi","year":"1999","unstructured":"Hashiguchi K et al (1999) Construction of an L-isoleucine overproducing strain of Escherichia coli K-12. Biosci Biotechnol Biochem 63(4):672\u2013679","journal-title":"Biosci Biotechnol Biochem"},{"issue":"1","key":"337_CR45","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1128\/jb.126.1.56-63.1976","volume":"126","author":"DH Calhoun","year":"1976","unstructured":"Calhoun DH (1976) Threonine deaminase from Escherichia coli: feedback-hypersensitive enzyme from a genetic regulatory mutant. J Bacteriol 126(1):56\u201363","journal-title":"J Bacteriol"},{"issue":"3","key":"337_CR46","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1002\/bab.1963","volume":"68","author":"Y Zhang","year":"2021","unstructured":"Zhang Y et al (2021) Metabolic engineering of Corynebacterium glutamicum WM001 to improve l-isoleucine production. Biotechnol Appl Biochem 68(3):568\u2013584","journal-title":"Biotechnol Appl Biochem"},{"issue":"2","key":"337_CR47","doi-asserted-by":"crossref","first-page":"761","DOI":"10.1007\/s00253-014-5965-3","volume":"99","author":"J Lu","year":"2015","unstructured":"Lu J et al (2015) Characterization and modification of enzymes in the 2-ketoisovalerate biosynthesis pathway of Ralstonia eutropha H16. Appl Microbiol Biotechnol 99(2):761\u2013774","journal-title":"Appl Microbiol Biotechnol"},{"issue":"5","key":"337_CR48","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1016\/j.ymben.2012.06.002","volume":"14","author":"L Yin","year":"2012","unstructured":"Yin L et al (2012) Co-expression of feedback-resistant threonine dehydratase and acetohydroxy acid synthase increase L-isoleucine production in Corynebacterium glutamicum. Metab Eng 14(5):542\u2013550","journal-title":"Metab Eng"},{"issue":"1","key":"337_CR49","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1021\/acssynbio.4c00540","volume":"14","author":"J Song","year":"2025","unstructured":"Song J et al (2025) Metabolic engineering of Escherichia coli for self-induced production of l-isoleucine. ACS Synth Biol 14(1):179\u2013192","journal-title":"ACS Synth Biol"},{"issue":"2","key":"337_CR50","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.enzmictec.2012.04.003","volume":"51","author":"F Shi","year":"2012","unstructured":"Shi F et al (2012) Overexpression of NAD kinases improves the L-isoleucine biosynthesis in Corynebacterium glutamicum ssp. lactofermentum. Enzym Microb Technol 51(2):73\u201380","journal-title":"Enzym Microb Technol"},{"issue":"10","key":"337_CR51","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1007\/s10295-012-1155-4","volume":"39","author":"X Xie","year":"2012","unstructured":"Xie X et al (2012) Effect of transport proteins on L-isoleucine production with the L-isoleucine-producing strain Corynebacterium glutamicum YILW. J Ind Microbiol Biotechnol 39(10):1549\u20131556","journal-title":"J Ind Microbiol Biotechnol"},{"key":"337_CR52","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.ymben.2024.10.004","volume":"86","author":"N Lu","year":"2024","unstructured":"Lu N et al (2024) Growth-coupled production of L-isoleucine in Escherichia coli via metabolic engineering. Metab Eng 86:181\u2013193","journal-title":"Metab Eng"},{"issue":"2","key":"337_CR53","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1080\/00071668.2011.561282","volume":"52","author":"WA Dozier 3rd","year":"2011","unstructured":"Dozier 3rd WA et al (2011) Determination of the fourth and fifth limiting amino acids in broilers fed on diets containing maize, soybean meal and poultry by-product meal from 28 to 42 d of age. Br Poult Sci 52(2):238\u2013244","journal-title":"Br Poult Sci"},{"issue":"4","key":"337_CR54","volume":"100","author":"YN Zhang","year":"2021","unstructured":"Zhang YN et al (2021) The application of reduced dietary crude protein levels supplemented with additional amino acids in laying ducks. Poult Sci 100(4):100983","journal-title":"Poult Sci"},{"key":"337_CR55","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1186\/s40064-015-0927-5","volume":"4","author":"SF Liao","year":"2015","unstructured":"Liao SF, Wang T, Regmi N (2015) Lysine nutrition in swine and the related monogastric animals: muscle protein biosynthesis and beyond. Springerplus 4:147","journal-title":"Springerplus"},{"issue":"4","key":"337_CR56","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1002\/bit.22995","volume":"108","author":"JH Park","year":"2011","unstructured":"Park JH et al (2011) Fed-batch culture of Escherichia coli for L-valine production based on in silico flux response analysis. Biotechnol Bioeng 108(4):934\u2013946","journal-title":"Biotechnol Bioeng"},{"issue":"19","key":"337_CR57","doi-asserted-by":"crossref","first-page":"7797","DOI":"10.1073\/pnas.0702609104","volume":"104","author":"JH Park","year":"2007","unstructured":"Park JH et al (2007) Metabolic engineering of Escherichia coli for the production of L-valine based on transcriptome analysis and in silico gene knockout simulation. Proc Natl Acad Sci USA 104(19):7797\u20137802","journal-title":"Proc Natl Acad Sci USA"},{"issue":"20","key":"337_CR58","doi-asserted-by":"crossref","first-page":"8633","DOI":"10.1007\/s00253-016-7809-9","volume":"100","author":"Y Liu","year":"2016","unstructured":"Liu Y, Li Y, Wang X (2016) Acetohydroxyacid synthases: evolution, structure, and function. Appl Microbiol Biotechnol 100(20):8633\u20138649","journal-title":"Appl Microbiol Biotechnol"},{"issue":"1","key":"337_CR59","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1128\/AEM.71.1.207-213.2005","volume":"71","author":"V Elis\u00e1kov\u00e1","year":"2005","unstructured":"Elis\u00e1kov\u00e1 V et al (2005) Feedback-resistant acetohydroxy acid synthase increases valine production in Corynebacterium glutamicum. Appl Environ Microbiol 71(1):207\u2013213","journal-title":"Appl Environ Microbiol"},{"key":"337_CR60","volume":"129","author":"Y Liu","year":"2019","unstructured":"Liu Y et al (2019) The 138(th) residue of acetohydroxyacid synthase in Corynebacterium glutamicum is important for the substrate binding specificity. Enzym Microb Technol 129:109357","journal-title":"Enzym Microb Technol"},{"issue":"1","key":"337_CR61","doi-asserted-by":"crossref","first-page":"3632","DOI":"10.1038\/s41598-018-21926-5","volume":"8","author":"H Zhang","year":"2018","unstructured":"Zhang H et al (2018) Understanding the high L-valine production in Corynebacterium glutamicum VWB-1 using transcriptomics and proteomics. Sci Rep 8(1):3632","journal-title":"Sci Rep"},{"issue":"7","key":"337_CR62","doi-asserted-by":"crossref","first-page":"2079","DOI":"10.1128\/AEM.02826-06","volume":"73","author":"B Blombach","year":"2007","unstructured":"Blombach B et al (2007) L-valine production with pyruvate dehydrogenase complex-deficient Corynebacterium glutamicum. Appl Environ Microbiol 73(7):2079\u20132084","journal-title":"Appl Environ Microbiol"},{"issue":"7","key":"337_CR63","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1007\/s10295-010-0712-y","volume":"37","author":"I Denina","year":"2010","unstructured":"Denina I et al (2010) Factors enhancing L-valine production by the growth-limited L-isoleucine auxotrophic strain Corynebacterium glutamicum DeltailvA DeltapanB ilvNM13 (pECKAilvBNC). J Ind Microbiol Biotechnol 37(7):689\u2013699","journal-title":"J Ind Microbiol Biotechnol"},{"issue":"3","key":"337_CR64","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.jbiotec.2008.12.005","volume":"139","author":"J Hol\u00e1tko","year":"2009","unstructured":"Hol\u00e1tko J et al (2009) Metabolic engineering of the L-valine biosynthesis pathway in Corynebacterium glutamicum using promoter activity modulation. J Biotechnol 139(3):203\u2013210","journal-title":"J Biotechnol"},{"key":"337_CR65","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.ymben.2015.03.004","volume":"29","author":"C Chen","year":"2015","unstructured":"Chen C et al (2015) Metabolic engineering of Corynebacterium glutamicum ATCC13869 for L-valine production. Metab Eng 29:66\u201375","journal-title":"Metab Eng"},{"key":"337_CR66","volume":"359","author":"Y Hao","year":"2022","unstructured":"Hao Y et al (2022) High-level production of L-valine in Escherichia coli using multi-modular engineering. Bioresour Technol 359:127461","journal-title":"Bioresour Technol"},{"key":"337_CR67","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/S0022-3476(62)80109-7","volume":"60","author":"VH Auerbach","year":"1962","unstructured":"Auerbach VH et al (1962) Histidinemia. A deficiency in histidase resulting in the urinary excretion of histidine and of imidazolepyruvic acid. J Pediatr 60:487\u2013497","journal-title":"J Pediatr"},{"issue":"2","key":"337_CR68","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1111\/j.1365-2249.2011.04519.x","volume":"167","author":"S Hasegawa","year":"2012","unstructured":"Hasegawa S et al (2012) Cysteine, histidine and glycine exhibit anti-inflammatory effects in human coronary arterial endothelial cells. Clin Exp Immunol 167(2):269\u2013274","journal-title":"Clin Exp Immunol"},{"issue":"5","key":"337_CR69","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1007\/s00125-013-2839-7","volume":"56","author":"RN Feng","year":"2013","unstructured":"Feng RN et al (2013) Histidine supplementation improves insulin resistance through suppressed inflammation in obese women with the metabolic syndrome: a randomised controlled trial. Diabetologia 56(5):985\u2013994","journal-title":"Diabetologia"},{"issue":"Suppl 1","key":"337_CR70","doi-asserted-by":"crossref","first-page":"2570s","DOI":"10.1093\/jn\/nxaa079","volume":"150","author":"ME Brosnan","year":"2020","unstructured":"Brosnan ME, Brosnan JT (2020) Histidine metabolism and function. J Nutr 150(Suppl 1):2570s\u20132575s","journal-title":"J Nutr"},{"issue":"11","key":"337_CR71","doi-asserted-by":"crossref","first-page":"1093","DOI":"10.3390\/antiox9111093","volume":"9","author":"W Kopec","year":"2020","unstructured":"Kopec W et al (2020) Antioxidative characteristics of chicken breast meat and blood after diet supplementation with carnosine, L-histidine, and \u03b2-alanine. Antioxidants (Basel) 9(11):1093","journal-title":"Antioxidants (Basel)"},{"issue":"2","key":"337_CR72","volume":"5","author":"JJ DiNicolantonio","year":"2018","unstructured":"DiNicolantonio JJ, McCarty MF, OKeefe JH (2018) Role of dietary histidine in the prevention of obesity and metabolic syndrome. Open Heart 5(2):e000676","journal-title":"Open Heart"},{"key":"337_CR73","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.copbio.2014.05.004","volume":"30","author":"VF Wendisch","year":"2014","unstructured":"Wendisch VF (2014) Microbial production of amino acids and derived chemicals: synthetic biology approaches to strain development. Curr Opin Biotechnol 30:51\u201358","journal-title":"Curr Opin Biotechnol"},{"issue":"1","key":"337_CR74","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1111\/1751-7915.12055","volume":"7","author":"RK Kulis-Horn","year":"2014","unstructured":"Kulis-Horn RK, Persicke M, Kalinowski J (2014) Histidine biosynthesis, its regulation and biotechnological application in Corynebacterium glutamicum. Microb Biotechnol 7(1):5\u201325","journal-title":"Microb Biotechnol"},{"issue":"1","key":"337_CR75","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1021\/sb400059y","volume":"3","author":"G Schendzielorz","year":"2014","unstructured":"Schendzielorz G et al (2014) Taking control over control: use of product sensing in single cells to remove flux control at key enzymes in biosynthesis pathways. ACS Synth Biol 3(1):21\u201329","journal-title":"ACS Synth Biol"},{"issue":"7","key":"337_CR76","doi-asserted-by":"crossref","first-page":"1813","DOI":"10.1021\/acssynbio.0c00163","volume":"9","author":"H Wu","year":"2020","unstructured":"Wu H et al (2020) Highly efficient production of l-histidine from glucose by metabolically engineered Escherichia coli. ACS Synth Biol 9(7):1813\u20131822","journal-title":"ACS Synth Biol"},{"issue":"4","key":"337_CR77","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1271\/bbb.58.635","volume":"58","author":"T Mizukami","year":"1994","unstructured":"Mizukami T et al (1994) Cloning of the ATP phosphoribosyl transferase gene of Corynebacterium glutamicum and application of the gene to L-histidine production. Biosci Biotechnol Biochem 58(4):635\u2013638","journal-title":"Biosci Biotechnol Biochem"},{"issue":"1","key":"337_CR78","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1186\/s12934-018-0890-2","volume":"17","author":"EA Malykh","year":"2018","unstructured":"Malykh EA et al (2018) Specific features of L-histidine production by Escherichia coli concerned with feedback control of AICAR formation and inorganic phosphate\/metal transport. Microb Cell Factories 17(1):42","journal-title":"Microb Cell Factories"},{"issue":"4","key":"337_CR79","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1021\/acssynbio.3c00026","volume":"12","author":"M Chai","year":"2023","unstructured":"Chai M et al (2023) Combinatorial protein engineering and metabolic engineering for efficient synthesis of l-histidine in Corynebacterium glutamicum. ACS Synth Biol 12(4):1275\u20131286","journal-title":"ACS Synth Biol"},{"key":"337_CR80","doi-asserted-by":"crossref","first-page":"165521","DOI":"10.1016\/j.cej.2025.165521","volume":"520","author":"F Yang","year":"2025","unstructured":"Yang F et al (2025) Development of Escherichia coli by combining channel engineering and energy engineering for the production of L-histidine. Chem Eng J 520:165521","journal-title":"Chem Eng J"},{"issue":"1","key":"337_CR81","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1186\/s12884-016-0978-9","volume":"16","author":"ZQ Zhang","year":"2016","unstructured":"Zhang ZQ et al (2016) Maternal and cord blood adiponectin levels in relation to post-natal body size in infants in the first year of life: a prospective study. BMC Pregnancy Childbirth 16(1):189","journal-title":"BMC Pregnancy Childbirth"},{"key":"337_CR82","volume":"81","author":"M Wu","year":"2020","unstructured":"Wu M et al (2020) Arginine accelerates intestinal health through cytokines and intestinal microbiota. Int Immunopharmacol 81:106029","journal-title":"Int Immunopharmacol"},{"issue":"10 Suppl","key":"337_CR83","doi-asserted-by":"crossref","first-page":"2854S","DOI":"10.1093\/jn\/134.10.2854S","volume":"134","author":"T Utagawa","year":"2004","unstructured":"Utagawa T (2004) Production of arginine by fermentation. J Nutr 134(10 Suppl):2854S\u20132857S; discussion 2895S","journal-title":"J Nutr"},{"key":"337_CR84","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1186\/s12934-014-0166-4","volume":"13","author":"JH Shin","year":"2014","unstructured":"Shin JH, Lee SY (2014) Metabolic engineering of microorganisms for the production of L-arginine and its derivatives. Microb Cell Factories 13:166","journal-title":"Microb Cell Factories"},{"issue":"9","key":"337_CR85","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1007\/s10482-016-0719-0","volume":"109","author":"Y Li","year":"2016","unstructured":"Li Y et al (2016) Metabolic engineering of Corynebacterium glutamicum for methionine production by removing feedback inhibition and increasing NADPH level. Antonie Van Leeuwenhoek 109(9):1185\u20131197","journal-title":"Antonie Van Leeuwenhoek"},{"issue":"2","key":"337_CR86","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1007\/s10295-016-1885-9","volume":"44","author":"J Zhang","year":"2017","unstructured":"Zhang J et al (2017) Reengineering of the feedback-inhibition enzyme N-acetyl-L-glutamate kinase to enhance L-arginine production in Corynebacterium crenatum. J Ind Microbiol Biotechnol 44(2):271\u2013283","journal-title":"J Ind Microbiol Biotechnol"},{"issue":"1","key":"337_CR87","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1007\/s10295-018-2103-8","volume":"46","author":"M Zhan","year":"2019","unstructured":"Zhan M et al (2019) Metabolic engineering of Corynebacterium glutamicum for improved L-arginine synthesis by enhancing NADPH supply. J Ind Microbiol Biotechnol 46(1):45\u201354","journal-title":"J Ind Microbiol Biotechnol"},{"key":"337_CR88","doi-asserted-by":"crossref","first-page":"4618","DOI":"10.1038\/ncomms5618","volume":"5","author":"SH Park","year":"2014","unstructured":"Park SH et al (2014) Metabolic engineering of Corynebacterium glutamicum for L-arginine production. Nat Commun 5:4618","journal-title":"Nat Commun"},{"key":"337_CR89","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.ymben.2023.02.003","volume":"76","author":"S Jiang","year":"2023","unstructured":"Jiang S et al (2023) Metabolic reprogramming and biosensor-assisted mutagenesis screening for high-level production of L-arginine in Escherichia coli. Metab Eng 76:146\u2013157","journal-title":"Metab Eng"},{"issue":"15","key":"337_CR90","doi-asserted-by":"crossref","first-page":"5224","DOI":"10.1128\/JB.01782-07","volume":"190","author":"J Bouvier","year":"2008","unstructured":"Bouvier J et al (2008) Lysine represses transcription of the Escherichia coli dapB gene by preventing its activation by the ArgP activator. J Bacteriol 190(15):5224\u20135229","journal-title":"J Bacteriol"},{"issue":"5","key":"337_CR91","doi-asserted-by":"crossref","first-page":"1087","DOI":"10.1006\/jmbi.1999.3308","volume":"294","author":"RT Celis","year":"1999","unstructured":"Celis RT (1999) Repression and activation of arginine transport genes in Escherichia coli K 12 by the ArgP protein. J Mol Biol 294(5):1087\u20131095","journal-title":"J Mol Biol"},{"issue":"20","key":"337_CR92","doi-asserted-by":"crossref","first-page":"5657","DOI":"10.1128\/JB.00947-12","volume":"194","author":"CN Marbaniang","year":"2012","unstructured":"Marbaniang CN, Gowrishankar J (2012) Transcriptional cross-regulation between Gram-negative and gram-positive bacteria, demonstrated using ArgP-argO of Escherichia coli and LysG-lysE of Corynebacterium glutamicum. J Bacteriol 194(20):5657\u20135666","journal-title":"J Bacteriol"},{"issue":"3","key":"337_CR93","first-page":"176","volume":"22","author":"S Kinoshita","year":"1958","unstructured":"Kinoshita S, Nakayama K, Akita S (1958) Taxonomical study of glutamic acid accumulating bacteria, Micrococcus glutamicus nov. sp. J Agric Chem Soc Jpn 22(3):176\u2013185","journal-title":"J Agric Chem Soc Jpn"}],"container-title":["Advances in Biochemical Engineering\/Biotechnology"],"original-title":[],"link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/10_2026_337","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T20:28:35Z","timestamp":1791491315000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/10_2026_337"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":93,"URL":"https:\/\/doi.org\/10.1007\/10_2026_337","relation":{},"ISSN":["0724-6145","1616-8542"],"issn-type":[{"value":"0724-6145","type":"print"},{"value":"1616-8542","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026]]},"assertion":[{"value":"9 October 2026","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}