{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T05:32:41Z","timestamp":1791178361800,"version":"4.1.0"},"publisher-location":"Berlin, Heidelberg","reference-count":239,"publisher":"Springer Berlin Heidelberg","isbn-type":[{"value":"9783540776031","type":"print"},{"value":"9783540776048","type":"electronic"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008]]},"DOI":"10.1007\/112_2008_802","type":"book-chapter","created":{"date-parts":[[2008,4,18]],"date-time":"2008-04-18T13:02:39Z","timestamp":1208523759000},"page":"93-125","source":"Crossref","is-referenced-by-count":40,"title":["Lipid homeostasis in macrophages \u2013 Implications for atherosclerosis"],"prefix":"10.1007","author":[{"given":"G.","family":"Schmitz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Grandl","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","published-online":{"date-parts":[[2008,4,19]]},"reference":[{"key":"802_CR1","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1161\/01.ATV.0000133194.94939.42","volume":"24","author":"M Abedin","year":"2004","unstructured":"Abedin\u00a0M, Tintut\u00a0Y, Demer\u00a0LL (2004) Vascular calcification: mechanisms and clinical ramifications. Arterioscler Thromb Vasc Biol 24:1161\u20131170","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"802_CR2","doi-asserted-by":"crossref","first-page":"5533","DOI":"10.1016\/j.febslet.2006.08.061","volume":"580","author":"N Anderson","year":"2006","unstructured":"Anderson\u00a0N, Borlak\u00a0J (2006) Drug-induced phospholipidosis. FEBS Lett 580:5533\u20135540","journal-title":"FEBS Lett"},{"key":"802_CR3","doi-asserted-by":"crossref","first-page":"1952","DOI":"10.1016\/S0022-2275(20)32356-7","volume":"41","author":"R Arakawa","year":"2000","unstructured":"Arakawa\u00a0R, Abe-Dohmae\u00a0S, Asai\u00a0M, et\u00a0al. (2000) Involvement of caveolin-1 in cholesterol enrichment of high density lipoprotein during its assembly by apolipoprotein and THP-1 cells. J Lipid Res 41:1952\u20131962","journal-title":"J Lipid Res"},{"key":"802_CR4","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1016\/S0022-2275(20)32444-5","volume":"40","author":"SJ Avart","year":"1999","unstructured":"Avart\u00a0SJ, Bernard\u00a0DW, Jerome WG et\u00a0al. (1999) Cholesteryl ester hydrolysis in J774 macrophages occurs in the cytoplasm and lysosomes. J Lipid Res 40:405\u2013414","journal-title":"J Lipid Res"},{"key":"802_CR5","doi-asserted-by":"crossref","first-page":"5399","DOI":"10.1091\/mbc.e04-03-0182","volume":"15","author":"SM Bared","year":"2004","unstructured":"Bared\u00a0SM, Buechler\u00a0C, Boettcher\u00a0A, et\u00a0al. (2004) Association of ABCA1 with syntaxin 13 and flotillin-1 and enhanced phagocytosis in tangier cells. Mol Biol Cell 15:5399\u20135407","journal-title":"Mol Biol Cell"},{"key":"802_CR6","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1161\/01.ATV.8.3.288","volume":"8","author":"U Beisiegel","year":"1988","unstructured":"Beisiegel\u00a0U, Weber\u00a0W, Havinga JR et\u00a0al. (1988) Apolipoprotein E-binding proteins isolated from dog and human liver. Arteriosclerosis 8:288\u2013297","journal-title":"Arteriosclerosis"},{"key":"802_CR7","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/0891-5849(95)02173-6","volume":"20","author":"JA Berliner","year":"1996","unstructured":"Berliner\u00a0JA, Heinecke\u00a0JW (1996) The role of oxidized lipoproteins in atherogenesis. Free Radic Biol Med 20:707\u2013727","journal-title":"Free Radic Biol Med"},{"key":"802_CR8","doi-asserted-by":"crossref","first-page":"1959","DOI":"10.1084\/jem.182.6.1959","volume":"182","author":"S Bhakdi","year":"1995","unstructured":"Bhakdi\u00a0S, Dorweiler\u00a0B, Kirchmann\u00a0R, et\u00a0al. (1995) On the pathogenesis of atherosclerosis: enzymatic transformation of human low density lipoprotein to an atherogenic moiety. J Exp Med 182:1959\u20131971","journal-title":"J Exp Med"},{"key":"802_CR9","doi-asserted-by":"crossref","first-page":"2348","DOI":"10.1161\/01.ATV.19.10.2348","volume":"19","author":"S Bhakdi","year":"1999","unstructured":"Bhakdi\u00a0S, Torzewski\u00a0M, Klouche\u00a0M, et\u00a0al. (1999) Complement and atherogenesis: binding of CRP to degraded, nonoxidized LDL enhances complement activation. Arterioscler Thromb Vasc Biol 19:2348\u20132354","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"802_CR10","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1172\/JCI200420479","volume":"114","author":"CJ Binder","year":"2004","unstructured":"Binder\u00a0CJ, Hartvigsen\u00a0K, Chang\u00a0MK, et\u00a0al. (2004) IL-5 links adaptive and natural immunity specific for epitopes of oxidized LDL and protects from atherosclerosis. J Clin Invest 114:427\u2013437","journal-title":"J Clin Invest"},{"key":"802_CR11","doi-asserted-by":"crossref","first-page":"21869","DOI":"10.1074\/jbc.M603025200","volume":"281","author":"M Binder","year":"2006","unstructured":"Binder\u00a0M, Liebisch\u00a0G, Langmann\u00a0T, et\u00a0al. (2006) Metabolic profiling of glycerophospholipid synthesis in fibroblasts loaded with free cholesterol and modified low density lipoproteins. J Biol Chem 281:21869\u201321877","journal-title":"J Biol Chem"},{"key":"802_CR12","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1038\/11914","volume":"22","author":"M Bodzioch","year":"1999","unstructured":"Bodzioch\u00a0M, Orso\u00a0E, Klucken\u00a0J, et\u00a0al. (1999) The gene encoding ATP-binding cassette transporter 1 is mutated in Tangier disease. Nat Genet 22:347\u2013351","journal-title":"Nat Genet"},{"key":"802_CR13","doi-asserted-by":"crossref","first-page":"63","DOI":"10.2174\/1570161052773861","volume":"3","author":"JJ Boyle","year":"2005","unstructured":"Boyle\u00a0JJ (2005) Macrophage activation in atherosclerosis: pathogenesis and pharmacology of plaque rupture. Curr Vasc Pharmacol 3:63\u201368","journal-title":"Curr Vasc Pharmacol"},{"issue":"Suppl 1","key":"802_CR14","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1590\/S0074-02762005000900020","volume":"100","author":"PT Bozza","year":"2005","unstructured":"Bozza\u00a0PT, Bandeira-Melo\u00a0C (2005) Mechanisms of leukocyte lipid body formation and function in inflammation. Mem Inst Oswaldo Cruz 100(Suppl 1):113\u2013120","journal-title":"Mem Inst Oswaldo Cruz"},{"key":"802_CR15","doi-asserted-by":"crossref","first-page":"2547","DOI":"10.1194\/jlr.R700014-JLR200","volume":"48","author":"DL Brasaemle","year":"2007","unstructured":"Brasaemle\u00a0DL (2007) Thematic review series: adipocyte biology. The perilipin family of structural lipid droplet proteins: stabilization of lipid droplets and control of lipolysis. J Lipid Res 48:2547\u20132559","journal-title":"J Lipid Res"},{"key":"802_CR16","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/S1388-1981(99)00179-1","volume":"1483","author":"DL Brasaemle","year":"2000","unstructured":"Brasaemle\u00a0DL, Levin\u00a0DM, Adler-Wailes\u00a0DC, et\u00a0al. (2000) The lipolytic stimulation of 3T3-L1 adipocytes promotes the translocation of hormone-sensitive lipase to the surfaces of lipid storage droplets. Biochim Biophys Acta 1483:251\u2013262","journal-title":"Biochim Biophys Acta"},{"key":"802_CR17","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1038\/11905","volume":"22","author":"A Brooks-Wilson","year":"1999","unstructured":"Brooks-Wilson\u00a0A, Marcil\u00a0M, Clee\u00a0SM, et\u00a0al. (1999) Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency. Nat Genet 22:336\u2013345","journal-title":"Nat Genet"},{"key":"802_CR18","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/S0092-8674(00)80213-5","volume":"89","author":"MS Brown","year":"1997","unstructured":"Brown\u00a0MS, Goldstein\u00a0JL (1997) The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a\u00a0membrane-bound transcription factor. Cell 89:331\u2013340","journal-title":"Cell"},{"key":"802_CR19","doi-asserted-by":"crossref","first-page":"11041","DOI":"10.1073\/pnas.96.20.11041","volume":"96","author":"MS Brown","year":"1999","unstructured":"Brown\u00a0MS, Goldstein\u00a0JL (1999) A\u00a0proteolytic pathway that controls the cholesterol content of membranes, cells, and blood. Proc Natl Acad Sci USA 96:11041\u201311048","journal-title":"Proc Natl Acad Sci USA"},{"key":"802_CR20","doi-asserted-by":"crossref","first-page":"41307","DOI":"10.1074\/jbc.C200436200","volume":"277","author":"C Buechler","year":"2002","unstructured":"Buechler\u00a0C, Bared\u00a0SM, Aslanidis\u00a0C, et\u00a0al. (2002a) Molecular and functional interaction of the ATP-binding cassette transporter A1 with Fas-associated death domain protein. J Biol Chem 277:41307\u201341310","journal-title":"J Biol Chem"},{"key":"802_CR21","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/S0006-291X(02)00303-0","volume":"293","author":"C Buechler","year":"2002","unstructured":"Buechler\u00a0C, Boettcher\u00a0A, Bared\u00a0SM, et\u00a0al. (2002b) The carboxyterminus of the ATP-binding cassette transporter A1 interacts with a\u00a0beta2-syntrophin\/utrophin complex. Biochem Biophys Res Commun 293:759\u2013765","journal-title":"Biochem Biophys Res Commun"},{"key":"802_CR22","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S1388-1981(01)00121-4","volume":"1532","author":"C Buechler","year":"2001","unstructured":"Buechler\u00a0C, Ritter\u00a0M, Duong\u00a0CQ, et\u00a0al. (2001) Adipophilin is a\u00a0sensitive marker for lipid loading in human blood monocytes. Biochim Biophys Acta 1532:97\u2013104","journal-title":"Biochim Biophys Acta"},{"key":"802_CR23","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1016\/j.cbpa.2007.05.035","volume":"11","author":"TD Butters","year":"2007","unstructured":"Butters\u00a0TD (2007) Gaucher disease. Curr Opin Chem Biol 11:412\u2013418","journal-title":"Curr Opin Chem Biol"},{"key":"802_CR24","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1002\/jlb.38.2.341","volume":"38","author":"MK Cathcart","year":"1985","unstructured":"Cathcart\u00a0MK, Morel\u00a0DW, Chisolm GM III. (1985) Monocytes and neutrophils oxidize low density lipoprotein making it cytotoxic. J Leukoc Biol 38:341\u2013350","journal-title":"J Leukoc Biol"},{"key":"802_CR25","doi-asserted-by":"crossref","first-page":"4992","DOI":"10.1016\/S0021-9258(18)42929-8","volume":"267","author":"FF Chao","year":"1992","unstructured":"Chao\u00a0FF, Blanchette-Mackie\u00a0EJ, et\u00a0al. (1992) Hydrolysis of cholesteryl ester in low density lipoprotein converts this lipoprotein to a\u00a0liposome. J Biol Chem 267:4992\u20134998","journal-title":"J Biol Chem"},{"key":"802_CR26","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1038\/83336","volume":"7","author":"A Chawla","year":"2001","unstructured":"Chawla\u00a0A, Barak\u00a0Y, Nagy\u00a0L, et\u00a0al. (2001) PPAR-gamma dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation. Nat Med 7:48\u201352","journal-title":"Nat Med"},{"key":"802_CR27","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1073\/pnas.0337331100","volume":"100","author":"A Chawla","year":"2003","unstructured":"Chawla\u00a0A, Lee\u00a0CH, Barak\u00a0Y, et\u00a0al. (2003) PPARdelta is a\u00a0very low-density lipoprotein sensor in macrophages. Proc Natl Acad Sci USA 100:1268\u20131273","journal-title":"Proc Natl Acad Sci USA"},{"key":"802_CR28","doi-asserted-by":"crossref","first-page":"43564","DOI":"10.1074\/jbc.M107938200","volume":"276","author":"W Chen","year":"2001","unstructured":"Chen\u00a0W, Sun\u00a0Y, Welch\u00a0C, et\u00a0al. (2001) Preferential ATP-binding cassette transporter A1-mediated cholesterol efflux from late endosomes\/lysosomes. J Biol Chem 276:43564\u201343569","journal-title":"J Biol Chem"},{"key":"802_CR29","doi-asserted-by":"crossref","first-page":"3197","DOI":"10.1091\/mbc.e05-12-1101","volume":"17","author":"ZJ Cheng","year":"2006","unstructured":"Cheng\u00a0ZJ, Singh\u00a0RD, Sharma\u00a0DK, et\u00a0al. (2006) Distinct mechanisms of clathrin-independent endocytosis have unique sphingolipid requirements. Mol Biol Cell 17:3197\u20133210","journal-title":"Mol Biol Cell"},{"key":"802_CR30","doi-asserted-by":"crossref","first-page":"2411","DOI":"10.1161\/01.CIR.101.20.2411","volume":"101","author":"G Chinetti","year":"2000","unstructured":"Chinetti\u00a0G, Gbaguidi\u00a0FG, Griglio\u00a0S, et\u00a0al. (2000) CLA-1\/SR-BI is expressed in atherosclerotic lesion macrophages and regulated by activators of peroxisome proliferator-activated receptors. Circulation 101:2411\u20132417","journal-title":"Circulation"},{"key":"802_CR31","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1038\/83348","volume":"7","author":"G Chinetti","year":"2001","unstructured":"Chinetti\u00a0G, Lestavel\u00a0S, Bocher\u00a0V, et\u00a0al. (2001) PPAR-alpha and PPAR-gamma activators induce cholesterol removal from human macrophage foam cells through stimulation of the ABCA1 pathway. Nat Med 7:53\u201358","journal-title":"Nat Med"},{"key":"802_CR32","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1172\/JCI0215420","volume":"109","author":"A Choudhury","year":"2002","unstructured":"Choudhury\u00a0A, Dominguez\u00a0M, Puri\u00a0V, et\u00a0al. (2002) Rab proteins mediate Golgi transport of caveola-internalized glycosphingolipids and correct lipid trafficking in Niemann\u2013Pick C cells. J Clin Invest 109:1541\u20131550","journal-title":"J Clin Invest"},{"key":"802_CR33","doi-asserted-by":"crossref","first-page":"425","DOI":"10.7326\/0003-4819-146-6-200703200-00007","volume":"146","author":"JT Clarke","year":"2007","unstructured":"Clarke\u00a0JT (2007) Narrative review: Fabry disease. Ann Intern Med 146:425\u2013433","journal-title":"Ann Intern Med"},{"issue":"Suppl 2","key":"802_CR34","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1038\/sj.cdd.4401751","volume":"12","author":"P Codogno","year":"2005","unstructured":"Codogno\u00a0P, Meijer\u00a0AJ (2005) Autophagy and signaling: their role in cell survival and cell death. Cell Death Differ 12(Suppl 2):1509\u20131518","journal-title":"Cell Death Differ"},{"key":"802_CR35","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1161\/01.CIR.103.7.926","volume":"103","author":"M Crisby","year":"2001","unstructured":"Crisby\u00a0M, Nordin-Fredriksson\u00a0G, Shah\u00a0PK, et\u00a0al. (2001) Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: implications for plaque stabilization. Circulation 103:926\u2013933","journal-title":"Circulation"},{"key":"802_CR36","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.tcb.2003.12.002","volume":"14","author":"AM Cuervo","year":"2004","unstructured":"Cuervo\u00a0AM (2004) Autophagy: in sickness and in health. Trends Cell Biol 14:70\u201377","journal-title":"Trends Cell Biol"},{"key":"802_CR37","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1146\/annurev.immunol.15.1.203","volume":"15","author":"M Daeron","year":"1997","unstructured":"Daeron\u00a0M (1997) Fc receptor biology. Annu Rev Immunol 15:203\u2013234","journal-title":"Annu Rev Immunol"},{"key":"802_CR38","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1007\/BF02693938","volume":"9","author":"S Devaraj","year":"2007","unstructured":"Devaraj\u00a0S, Rogers\u00a0J, Jialal\u00a0I (2007) Statins and biomarkers of inflammation. Curr Atheroscler Rep 9:33\u201341","journal-title":"Curr Atheroscler Rep"},{"key":"802_CR39","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/S0021-9150(01)00518-4","volume":"159","author":"W Diederich","year":"2001","unstructured":"Diederich\u00a0W, Orso\u00a0E, Drobnik\u00a0W, et\u00a0al. (2001) Apolipoprotein AI and HDL(3) inhibit spreading of primary human monocytes through a\u00a0mechanism that involves cholesterol depletion and regulation of CDC42. Atherosclerosis 159:313\u2013324","journal-title":"Atherosclerosis"},{"key":"802_CR40","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1046\/j.1462-5822.2002.00164.x","volume":"4","author":"BR Dorn","year":"2002","unstructured":"Dorn\u00a0BR, Dunn WA Jr., Progulske-Fox\u00a0A (2002) Bacterial interactions with the autophagic pathway. Cell Microbiol 4:1\u201310","journal-title":"Cell Microbiol"},{"key":"802_CR41","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1034\/j.1600-0854.2002.030404.x","volume":"3","author":"W Drobnik","year":"2002","unstructured":"Drobnik\u00a0W, Borsukova\u00a0H, Bottcher\u00a0A, et\u00a0al. (2002) Apo AI\/ABCA1-dependent and HDL3-mediated lipid efflux from compositionally distinct cholesterol-based microdomains. Traffic 3:268\u2013278","journal-title":"Traffic"},{"key":"802_CR42","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1016\/j.bbrc.2006.11.087","volume":"352","author":"J Ecker","year":"2007","unstructured":"Ecker\u00a0J, Langmann\u00a0T, Moehle\u00a0C, et\u00a0al. (2007) Isomer specific effects of Conjugated Linoleic Acid on macrophage ABCG1 transcription by a\u00a0SREBP-1c dependent mechanism. Biochem Biophys Res Commun 352:805\u2013811","journal-title":"Biochem Biophys Res Commun"},{"key":"802_CR43","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.febslet.2004.04.048","volume":"566","author":"T Engel","year":"2004","unstructured":"Engel\u00a0T, Lueken\u00a0A, Bode\u00a0G, et\u00a0al. (2004) ADP-ribosylation factor (ARF)-like 7 (ARL7) is induced by cholesterol loading and participates in apolipoprotein AI-dependent cholesterol export. FEBS Lett 566:241\u2013246","journal-title":"FEBS Lett"},{"key":"802_CR44","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1038\/nm1025","volume":"10","author":"RM Evans","year":"2004","unstructured":"Evans\u00a0RM, Barish\u00a0GD, Wang\u00a0YX (2004) PPARs and the complex journey to obesity. Nat Med 10:355\u2013361","journal-title":"Nat Med"},{"key":"802_CR45","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.imbio.2005.05.010","volume":"210","author":"BO Fabriek","year":"2005","unstructured":"Fabriek\u00a0BO, Dijkstra\u00a0CD, van den Berg\u00a0TK (2005) The macrophage scavenger receptor CD163. Immunobiology 210:153\u2013160","journal-title":"Immunobiology"},{"issue":"Suppl 2","key":"802_CR46","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1111\/j.1472-8206.2007.00535.x","volume":"21","author":"M Farnier","year":"2007","unstructured":"Farnier\u00a0M (2007) Setting a\u00a0new standard in achieving superior efficacy: ezetimibe + simvastatin. Fundam Clin Pharmacol 21(Suppl 2):27\u201328","journal-title":"Fundam Clin Pharmacol"},{"key":"802_CR47","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1056\/NEJMe068012","volume":"354","author":"S Fazio","year":"2006","unstructured":"Fazio\u00a0S, Linton\u00a0M (2006) Failure of ACAT inhibition to retard atherosclerosis. N Engl J Med 354:1307\u20131309","journal-title":"N Engl J Med"},{"key":"802_CR48","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1172\/JCI10310","volume":"107","author":"S Fazio","year":"2001","unstructured":"Fazio\u00a0S, Major\u00a0AS, Swift\u00a0LL, et\u00a0al. (2001) Increased atherosclerosis in LDL receptor-null mice lacking ACAT1 in macrophages. J Clin Invest 107:163\u2013171","journal-title":"J Clin Invest"},{"issue":"Suppl 7","key":"802_CR49","doi-asserted-by":"crossref","first-page":"S7","DOI":"10.1016\/S1098-3597(07)80017-2","volume":"8","author":"VA Fonseca","year":"2007","unstructured":"Fonseca\u00a0VA (2007) Early identification and treatment of insulin resistance: impact on subsequent prediabetes and type 2 diabetes. Clin Cornerstone 8(Suppl 7):S7\u201318","journal-title":"Clin Cornerstone"},{"key":"802_CR50","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1016\/0092-8674(95)90193-0","volume":"83","author":"BM Forman","year":"1995","unstructured":"Forman\u00a0BM, Tontonoz\u00a0P, Chen\u00a0J, et\u00a0al. (1995) 15-Deoxy-delta 12, 14-prostaglandin J2 is a\u00a0ligand for the adipocyte determination factor PPAR gamma. Cell 83:803\u2013812","journal-title":"Cell"},{"key":"802_CR51","doi-asserted-by":"crossref","first-page":"38378","DOI":"10.1074\/jbc.M105805200","volume":"276","author":"X Fu","year":"2001","unstructured":"Fu\u00a0X, Menke\u00a0JG, Chen\u00a0Y, et\u00a0al. (2001) 27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells. J Biol Chem 276:38378\u201338387","journal-title":"J Biol Chem"},{"key":"802_CR52","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1006\/bbrc.2002.6356","volume":"290","author":"B Garner","year":"2002","unstructured":"Garner\u00a0B, Mellor\u00a0HR, Butters\u00a0TD, et\u00a0al. (2002) Modulation of THP-1 macrophage and cholesterol-loaded foam cell apolipoprotein E levels by glycosphingolipids. Biochem Biophys Res Commun 290:1361\u20131367","journal-title":"Biochem Biophys Res Commun"},{"key":"802_CR53","doi-asserted-by":"crossref","first-page":"9363","DOI":"10.1021\/bi010323n","volume":"40","author":"K Gaus","year":"2001","unstructured":"Gaus\u00a0K, Gooding\u00a0JJ, Dean\u00a0RT, et\u00a0al. (2001) A\u00a0kinetic model to evaluate cholesterol efflux from THP-1 macrophages to apolipoprotein A-1. Biochemistry 40:9363\u20139373","journal-title":"Biochemistry"},{"key":"802_CR54","doi-asserted-by":"crossref","first-page":"17852","DOI":"10.1074\/jbc.271.30.17852","volume":"271","author":"IC Gelissen","year":"1996","unstructured":"Gelissen\u00a0IC, Brown\u00a0AJ, Mander\u00a0EL, et\u00a0al. (1996) Sterol efflux is impaired from macrophage foam cells selectively enriched with 7-ketocholesterol. J Biol Chem 271:17852\u201317860","journal-title":"J Biol Chem"},{"key":"802_CR55","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1016\/S0022-2275(20)33409-X","volume":"40","author":"IC Gelissen","year":"1999","unstructured":"Gelissen\u00a0IC, Rye\u00a0KA, Brown\u00a0AJ, et\u00a0al. (1999) Oxysterol efflux from macrophage foam cells: the essential role of acceptor phospholipid. J Lipid Res 40:1636\u20131646","journal-title":"J Lipid Res"},{"key":"802_CR56","doi-asserted-by":"crossref","first-page":"24515","DOI":"10.1074\/jbc.M413862200","volume":"280","author":"EN Glaros","year":"2005","unstructured":"Glaros\u00a0EN, Kim\u00a0WS, Quinn\u00a0CM, et\u00a0al. (2005) Glycosphingolipid accumulation inhibits cholesterol efflux via the ABCA1\/apolipoprotein A-I pathway: 1-phenyl-2-decanoylamino-3-morpholino-1-propanol is a\u00a0novel cholesterol efflux accelerator. J Biol Chem 280:24515\u201324523","journal-title":"J Biol Chem"},{"key":"802_CR57","doi-asserted-by":"crossref","first-page":"1663","DOI":"10.4049\/jimmunol.164.4.1663","volume":"164","author":"C Godson","year":"2000","unstructured":"Godson\u00a0C, Mitchell\u00a0S, Harvey\u00a0K, et\u00a0al. (2000) Cutting edge: lipoxins rapidly stimulate nonphlogistic phagocytosis of apoptotic neutrophils by monocyte-derived macrophages. J Immunol 164:1663\u20131667","journal-title":"J Immunol"},{"key":"802_CR58","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.cell.2005.12.022","volume":"124","author":"JL Goldstein","year":"2006","unstructured":"Goldstein\u00a0JL, DeBose-Boyd\u00a0RA, Brown\u00a0MS (2006) Protein sensors for membrane sterols. Cell 124:35\u201346","journal-title":"Cell"},{"key":"802_CR59","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1002\/cyto.a.20080","volume":"61","author":"I Gombos","year":"2004","unstructured":"Gombos\u00a0I, Bacso\u00a0Z, Detre\u00a0C, et\u00a0al. (2004) Cholesterol sensitivity of detergent resistance: a\u00a0rapid flow cytometric test for detecting constitutive or induced raft association of membrane proteins. Cytometry A\u00a061:117\u2013126","journal-title":"Cytometry A"},{"key":"802_CR60","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1038\/nri1733","volume":"5","author":"S Gordon","year":"2005","unstructured":"Gordon\u00a0S, Taylor\u00a0PR (2005) Monocyte and macrophage heterogeneity. Nat Rev Immunol 5:953\u2013964","journal-title":"Nat Rev Immunol"},{"issue":"1","key":"802_CR61","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1189\/jlb.69.1.11","volume":"69","author":"E Grage-Griebenow","year":"2001","unstructured":"Grage-Griebenow\u00a0E, Flad\u00a0HD, Ernst\u00a0M (2001) Heterogeneity of human peripheral blood monocyte subsets. J Leukoc Biol 69(1):11\u201320","journal-title":"J Leukoc Biol"},{"key":"802_CR62","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/S0171-2985(00)80051-0","volume":"202","author":"E Grage-Griebenow","year":"2000","unstructured":"Grage-Griebenow\u00a0E, Flad\u00a0HD, Ernst\u00a0M, et\u00a0al. (2000) Human MO subsets as defined by expression of CD64 and CD16 differ in phagocytic activity and generation of oxygen intermediates. Immunobiology 202:42\u201350","journal-title":"Immunobiology"},{"key":"802_CR63","doi-asserted-by":"crossref","first-page":"3126","DOI":"10.1002\/eji.1830231213","volume":"23","author":"E Grage-Griebenow","year":"1993","unstructured":"Grage-Griebenow\u00a0E, Lorenzen\u00a0D, Fetting\u00a0R, et\u00a0al. (1993) Phenotypical and functional characterization of Fc gamma receptor I (CD64)-negative monocytes, a\u00a0minor human monocyte subpopulation with high accessory and antiviral activity. Eur J Immunol 23:3126\u20133135","journal-title":"Eur J Immunol"},{"key":"802_CR64","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1038\/nm1201-1332","volume":"7","author":"T Grand-Perret","year":"2001","unstructured":"Grand-Perret\u00a0T, Bouillot\u00a0A, Perrot\u00a0A, et\u00a0al. (2001) SCAP ligands are potent new lipid-lowering drugs. Nat Med 7:1332\u20131338","journal-title":"Nat Med"},{"key":"802_CR65","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1002\/cyto.a.20232","volume":"69","author":"M Grandl","year":"2006","unstructured":"Grandl\u00a0M, Bared S M, Liebisch\u00a0G, et\u00a0al. (2006) E-LDL and Ox-LDL differentially regulate ceramide and cholesterol raft microdomains in human Macrophages. Cytometry A\u00a069:189\u2013191","journal-title":"Cytometry A"},{"issue":"Pt 14","key":"802_CR66","doi-asserted-by":"crossref","first-page":"2953","DOI":"10.1242\/jcs.115.14.2953","volume":"115","author":"S Grimmer","year":"2002","unstructured":"Grimmer\u00a0S, van Deurs\u00a0B, Sandvig\u00a0K (2002) Membrane ruffling and macropinocytosis in A431 cells require cholesterol. J Cell Sci 115(Pt 14):2953\u20132962","journal-title":"J Cell Sci"},{"key":"802_CR67","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1097\/MOL.0b013e3282364add","volume":"18","author":"JR Guyton","year":"2007","unstructured":"Guyton\u00a0JR (2007) Niacin in cardiovascular prevention: mechanisms, efficacy, and safety. Curr Opin Lipidol 18:415\u2013420","journal-title":"Curr Opin Lipidol"},{"key":"802_CR68","doi-asserted-by":"crossref","first-page":"82U","DOI":"10.1016\/S0002-9149(98)00955-2","volume":"82","author":"JR Guyton","year":"1998","unstructured":"Guyton\u00a0JR, Capuzzi\u00a0DM (1998) Treatment of hyperlipidemia with combined niacin-statin regimens. Am J Cardiol 82:82U\u201384U","journal-title":"Am J Cardiol"},{"key":"802_CR69","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1172\/JCI110639","volume":"70","author":"DP Hajjar","year":"1982","unstructured":"Hajjar\u00a0DP, Weksler\u00a0BB, Falcone\u00a0DJ, et\u00a0al. (1982) Prostacyclin modulates cholesteryl ester hydrolytic activity by its effect on cyclic adenosine monophosphate in rabbit aortic smooth muscle cells. J Clin Invest 70:479\u2013488","journal-title":"J Clin Invest"},{"key":"802_CR70","doi-asserted-by":"crossref","first-page":"1430","DOI":"10.1161\/01.ATV.0000077207.49221.06","volume":"23","author":"JK Hakala","year":"2003","unstructured":"Hakala\u00a0JK, Oksjoki\u00a0R, Laine\u00a0P, et\u00a0al. (2003) Lysosomal enzymes are released from cultured human macrophages, hydrolyze LDL in vitro, and are present extracellularly in human atherosclerotic lesions. Arterioscler ThrombArterioscler Thromb Vasc Biol 23:1430\u20131436","journal-title":"Arterioscler ThrombArterioscler Thromb Vasc Biol"},{"key":"802_CR71","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1177\/019262339702500111","volume":"25","author":"WH Halliwell","year":"1997","unstructured":"Halliwell\u00a0WH (1997) Cationic amphiphilic drug-induced phospholipidosis. Toxicol Pathol 25:53\u201360","journal-title":"Toxicol Pathol"},{"key":"802_CR72","doi-asserted-by":"crossref","first-page":"3080","DOI":"10.1016\/S0021-9258(18)49957-7","volume":"266","author":"H Hara","year":"1991","unstructured":"Hara\u00a0H, Yokoyama\u00a0S (1991) Interaction of free apolipoproteins with macrophages. Formation of high density lipoprotein-like lipoproteins and reduction of cellular cholesterol. J Biol Chem 266:3080\u20133086","journal-title":"J Biol Chem"},{"key":"802_CR73","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1183\/09031936.06.00001506","volume":"28","author":"S Hodge","year":"2006","unstructured":"Hodge\u00a0S,Hodge\u00a0G, Brozyna\u00a0S, et\u00a0al. (2006) Azithromycin increases phagocytosis of apoptotic bronchial epithelial cells by alveolar macrophages. Eur Respir J 28:486\u2013495","journal-title":"Eur Respir J"},{"key":"802_CR74","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1016\/S0891-5849(00)00333-6","volume":"28","author":"S Horkko","year":"2000","unstructured":"Horkko\u00a0S, Binder\u00a0CJ, Shaw\u00a0PX, et\u00a0al. (2000) Immunological responses to oxidized LDL. Free Radic Biol Med 28:1771\u20131779","journal-title":"Free Radic Biol Med"},{"key":"802_CR75","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1172\/JCI4533","volume":"103","author":"S Horkko","year":"1999","unstructured":"Horkko\u00a0S, Bird\u00a0DA, Miller\u00a0E, et\u00a0al. (1999) Monoclonal autoantibodies specific for oxidized phospholipids or oxidized phospholipid-protein adducts inhibit macrophage uptake of oxidized low-density lipoproteins. J Clin Invest 103:117\u2013128","journal-title":"J Clin Invest"},{"key":"802_CR76","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1038\/22572","volume":"400","author":"JT Huang","year":"1999","unstructured":"Huang\u00a0JT, Welch J S, Ricote\u00a0M, et\u00a0al. (1999) Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12\/15-lipoxygenase. Nature 400:378\u2013382","journal-title":"Nature"},{"key":"802_CR77","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1038\/15507","volume":"23","author":"L Huang","year":"1999","unstructured":"Huang\u00a0L, Kuo\u00a0YM, Gitschier\u00a0J (1999) The pallid gene encodes a\u00a0novel, syntaxin 13-interacting protein involved in platelet storage pool deficiency. Nat Genet 23:329\u2013332","journal-title":"Nat Genet"},{"key":"802_CR78","doi-asserted-by":"crossref","first-page":"3218","DOI":"10.1161\/01.CIR.99.25.3218","volume":"99","author":"JA Hubacek","year":"1999","unstructured":"Hubacek\u00a0JA, Rothe\u00a0G, Pit'ha\u00a0J, et\u00a0al. (1999) C(-260)-->T polymorphism in the promoter of the CD14 monocyte receptor gene as a\u00a0risk factor for myocardial infarction. Circulation 99:3218\u20133220","journal-title":"Circulation"},{"key":"802_CR79","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S1388-1981(00)00042-1","volume":"1485","author":"A Huwiler","year":"2000","unstructured":"Huwiler\u00a0A, Kolter\u00a0T, Pfeilschifter\u00a0J, et\u00a0al. (2000) Physiology and pathophysiology of sphingolipid metabolism and signaling. Biochim Biophys Acta 1485:63\u201399","journal-title":"Biochim Biophys Acta"},{"key":"802_CR80","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1038\/nrm2336","volume":"9","author":"E Ikonen","year":"2008","unstructured":"Ikonen\u00a0E (2008) Cellular cholesterol trafficking and compartmentalization. Mol CellNat Rev Mol Cell Biol 9:125\u2013138","journal-title":"Mol CellNat Rev Mol Cell Biol"},{"key":"802_CR81","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1038\/35089558","volume":"2","author":"YA Ioannou","year":"2001","unstructured":"Ioannou\u00a0YA (2001) Multidrug permeases and subcellular cholesterol transport. Mol CellNat Rev Mol Cell Biol 2:657\u2013668","journal-title":"Mol CellNat Rev Mol Cell Biol"},{"key":"802_CR82","doi-asserted-by":"crossref","first-page":"15274","DOI":"10.1016\/S0021-9258(17)36602-4","volume":"269","author":"H Itabe","year":"1994","unstructured":"Itabe\u00a0H, Takeshima\u00a0E, Iwasaki\u00a0H, et\u00a0al. (1994) A\u00a0monoclonal antibody against oxidized lipoprotein recognizes foam cells in atherosclerotic lesions. Complex formation of oxidized phosphatidylcholines and polypeptides. J Biol Chem 269:15274\u201315279","journal-title":"J Biol Chem"},{"key":"802_CR83","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S0022-2275(20)37634-3","volume":"37","author":"H Itabe","year":"1996","unstructured":"Itabe\u00a0H, Yamamoto\u00a0H, Imanaka\u00a0T, et\u00a0al. (1996) Sensitive detection of oxidatively modified low density lipoprotein using a\u00a0monoclonal antibody. J Lipid Res 37:45\u201353","journal-title":"J Lipid Res"},{"key":"802_CR84","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1097\/01.mol.0000226116.35555.eb","volume":"17","author":"W Jessup","year":"2006","unstructured":"Jessup\u00a0W, Gelissen\u00a0IC, Gaus\u00a0K, et\u00a0al. (2006) Roles of ATP binding cassette transporters A1 and G1, scavenger receptor BI and membrane lipid domains in cholesterol export from macrophages. Curr Opin Lipidol 17:247\u2013257","journal-title":"Curr Opin Lipidol"},{"issue":"Pt 1","key":"802_CR85","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1042\/bst0320134","volume":"32","author":"W Jessup","year":"2004","unstructured":"Jessup\u00a0W, Kritharides\u00a0L, Stocker\u00a0R (2004) Lipid oxidation in atherogenesis: an overview. Biochem Soc Trans 32(Pt 1):134\u2013138","journal-title":"Biochem Soc Trans"},{"key":"802_CR86","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/S1537-1891(02)00174-X","volume":"38","author":"W Jessup","year":"2002","unstructured":"Jessup\u00a0W, Wilson\u00a0P, Gaus\u00a0K, et\u00a0al. (2002) Oxidized lipoproteins and macrophages. Vascul Pharmacol 38:239\u2013248","journal-title":"Vascul Pharmacol"},{"key":"802_CR87","doi-asserted-by":"crossref","first-page":"63","DOI":"10.4161\/auto.3427","volume":"3","author":"G Jia","year":"2007","unstructured":"Jia\u00a0G, Cheng\u00a0G, Agrawal\u00a0DK (2007) Autophagy of vascular smooth muscle cells in atherosclerotic lesions. Autophagy 3:63\u201364","journal-title":"Autophagy"},{"key":"802_CR88","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1038\/34184","volume":"391","author":"C Jiang","year":"1998","unstructured":"Jiang\u00a0C, Ting\u00a0AT, Seed\u00a0B (1998) PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines. Nature 391:82\u201386","journal-title":"Nature"},{"key":"802_CR89","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1161\/01.ATV.19.4.1051","volume":"19","author":"FY Jin","year":"1999","unstructured":"Jin\u00a0FY, Kamanna\u00a0VS, Kashyap\u00a0ML (1999) Niacin accelerates intracellular ApoB degradation by inhibiting triacylglycerol synthesis in human hepatoblastoma (HepG2) cells. Arterioscler ThrombArterioscler Thromb Vasc Biol 19:1051\u20131059","journal-title":"Arterioscler ThrombArterioscler Thromb Vasc Biol"},{"key":"802_CR90","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1038\/nm820","volume":"9","author":"SB Joseph","year":"2003","unstructured":"Joseph\u00a0SB, Castrillo\u00a0A, Laffitte\u00a0BA, et\u00a0al. (2003) Reciprocal regulation of inflammation and lipid metabolism by liver X receptors. Nat Med 9:213\u2013219","journal-title":"Nat Med"},{"key":"802_CR91","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1146\/annurev.physiol.68.033104.152158","volume":"68","author":"NY Kalaany","year":"2006","unstructured":"Kalaany\u00a0NY, Mangelsdorf\u00a0DJ (2006) LXRS and FXR: the yin and yang of cholesterol and fat metabolism. Annu Rev Physiol 68:159\u2013191","journal-title":"Annu Rev Physiol"},{"key":"802_CR92","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/0272-0590(91)90139-U","volume":"16","author":"R Kannan","year":"1991","unstructured":"Kannan\u00a0R, Sarma\u00a0JS, Guha\u00a0M, et\u00a0al. (1991) Amiodarone toxicity. II. Desethylamiodarone-induced phospholipidosis and ultrastructural changes during repeated administration in rats. Fundam Appl Toxicol 16:103\u2013109","journal-title":"Fundam Appl Toxicol"},{"key":"802_CR93","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1161\/01.ATV.21.6.1004","volume":"21","author":"M Kapinsky","year":"2001","unstructured":"Kapinsky\u00a0M, Torzewski\u00a0M, Buchler\u00a0C, et\u00a0al. (2001) Enzymatically degraded LDL preferentially binds to CD14(high) CD16(+) monocytes and induces foam cell formation mediated only in part by the class B scavenger-receptor CD36. Arterioscler ThrombArterioscler Thromb Vasc Biol 21:1004\u20131010","journal-title":"Arterioscler ThrombArterioscler Thromb Vasc Biol"},{"key":"802_CR95","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1016\/S0022-2275(20)39884-9","volume":"36","author":"EP Kilsdonk","year":"1995","unstructured":"Kilsdonk\u00a0EP, Morel\u00a0DW, Johnson\u00a0WJ, et\u00a0al. (1995) Inhibition of cellular cholesterol efflux by 25-hydroxycholesterol. J Lipid Res 36:505\u2013516","journal-title":"J Lipid Res"},{"key":"802_CR96","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1095\/biolreprod54.4.847","volume":"54","author":"C Kirchhoff","year":"1996","unstructured":"Kirchhoff\u00a0C, Osterhoff\u00a0C, Young\u00a0L (1996) Molecular cloning and characterization of HE1, a\u00a0major secretory protein of the human epididymis. Biol Reprod 54:847\u2013856","journal-title":"Biol Reprod"},{"issue":"Suppl E","key":"802_CR97","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1093\/eurheartj\/11.suppl_E.122","volume":"11","author":"T Kita","year":"1990","unstructured":"Kita\u00a0T, Ishii\u00a0K, Yokode\u00a0M, et\u00a0al. (1990) The role of oxidized low density lipoprotein in the pathogenesis of atherosclerosis. Eur Heart J 11(Suppl E):122\u2013127","journal-title":"Eur Heart J"},{"key":"802_CR98","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1016\/0092-8674(95)90194-9","volume":"83","author":"SA Kliewer","year":"1995","unstructured":"Kliewer\u00a0SA, Lenhard\u00a0JM, Willson\u00a0TM, et\u00a0al. (1995) A\u00a0prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation. Cell 83:813\u2013819","journal-title":"Cell"},{"key":"802_CR99","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.1161\/01.ATV.18.9.1376","volume":"18","author":"M Klouche","year":"1998","unstructured":"Klouche\u00a0M, Gottschling\u00a0S, Gerl\u00a0V, et\u00a0al. (1998) Atherogenic properties of enzymatically degraded LDL: selective induction of MCP-1 and cytotoxic effects on human macrophages. Arterioscler ThrombArterioscler Thromb Vasc Biol 18:1376\u20131385","journal-title":"Arterioscler ThrombArterioscler Thromb Vasc Biol"},{"key":"802_CR100","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1161\/01.ATV.19.3.784","volume":"19","author":"M Klouche","year":"1999","unstructured":"Klouche\u00a0M, May A\u00a0E, Hemmes\u00a0M, et\u00a0al. (1999) Enzymatically modified, nonoxidized LDL induces selective adhesion and transmigration of monocytes and T-lymphocytes through human endothelial cell monolayers. Arterioscler ThrombArterioscler Thromb Vasc Biol 19:784\u2013793","journal-title":"Arterioscler ThrombArterioscler Thromb Vasc Biol"},{"key":"802_CR101","doi-asserted-by":"crossref","first-page":"1799","DOI":"10.1161\/01.CIR.101.15.1799","volume":"101","author":"M Klouche","year":"2000","unstructured":"Klouche\u00a0M, Rose-John\u00a0S, Schmiedt\u00a0W, et\u00a0al. (2000) Enzymatically degraded, nonoxidized LDL induces human vascular smooth muscle cell activation, foam cell transformation, and proliferation. Circulation 101:1799\u20131805","journal-title":"Circulation"},{"key":"802_CR102","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1038\/10084","volume":"1","author":"T Kobayashi","year":"1999","unstructured":"Kobayashi\u00a0T, Beuchat\u00a0MH, Lindsay\u00a0M, et\u00a0al. (1999) Late endosomal membranes rich in lysobisphosphatidic acid regulate cholesterol transport. Nat Cell Biol 1:113\u2013118","journal-title":"Nat Cell Biol"},{"key":"802_CR103","first-page":"327","volume":"42","author":"UP Kodavanti","year":"1990","unstructured":"Kodavanti\u00a0UP, Mehendale\u00a0HM (1990) Cationic amphiphilic drugs and phospholipid storage disorder. Pharmacol Rev 42:327\u2013354","journal-title":"Pharmacol Rev"},{"key":"802_CR104","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0163-7827(91)90005-P","volume":"30","author":"RN Kolesnick","year":"1991","unstructured":"Kolesnick\u00a0RN (1991) Sphingomyelin and derivatives as cellular signals. Prog Lipid Res 30:1\u201338","journal-title":"Prog Lipid Res"},{"key":"802_CR105","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1002\/1097-4652(200009)184:3<285::AID-JCP2>3.0.CO;2-3","volume":"184","author":"RN Kolesnick","year":"2000","unstructured":"Kolesnick\u00a0RN, Goni\u00a0FM, Alonso\u00a0A\u00a0(2000) Compartmentalization of ceramide signaling: physical foundations and biological effects. J Cell Physiol 184:285\u2013300","journal-title":"J Cell Physiol"},{"key":"802_CR106","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1146\/annurev.cellbio.21.122303.120013","volume":"21","author":"T Kolter","year":"2005","unstructured":"Kolter\u00a0T, Sandhoff\u00a0K (2005) Principles of lysosomal membrane digestion: Stimulation of sphingolipid degradation by sphingolipid activator proteins and anionic lysosomal lipids. Annu Rev Cell Dev Biol 21:81\u2013103","journal-title":"Annu Rev Cell Dev Biol"},{"key":"802_CR107","doi-asserted-by":"crossref","first-page":"625","DOI":"10.2119\/2007-00087.Koyama","volume":"13","author":"H Koyama","year":"2007","unstructured":"Koyama\u00a0H, Yamamoto\u00a0H, Nishizawa\u00a0Y (2007) RAGE and soluble RAGE: potential therapeutic targets for cardiovascular diseases. Mol Med 13:625\u2013635","journal-title":"Mol Med"},{"key":"802_CR108","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1161\/01.ATV.15.2.276","volume":"15","author":"L Kritharides","year":"1995","unstructured":"Kritharides\u00a0L, Jessup\u00a0W, Mander\u00a0EL, et\u00a0al. (1995) Apolipoprotein A-I-mediated efflux of sterols from oxidized LDL-loaded macrophages. Arterioscler ThrombArterioscler Thromb Vasc Biol 15:276\u2013289","journal-title":"Arterioscler ThrombArterioscler Thromb Vasc Biol"},{"key":"802_CR109","first-page":"201","volume":"114","author":"HS Kruth","year":"1984","unstructured":"Kruth\u00a0HS (1984) Localization of unesterified cholesterol in human atherosclerotic lesions. Demonstration of filipin-positive, oil-red-O-negative particles. Am J Pathol 114:201\u2013208","journal-title":"Am J Pathol"},{"key":"802_CR110","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/S1097-2765(00)80210-5","volume":"4","author":"N Kubota","year":"1999","unstructured":"Kubota\u00a0N, Terauchi\u00a0Y, Miki\u00a0H, et\u00a0al. (1999) PPAR gamma mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance. Mol Cell 4:597\u2013609","journal-title":"Mol Cell"},{"key":"802_CR111","doi-asserted-by":"crossref","unstructured":"Kundu\u00a0M, Thompson\u00a0CB (2007) Autophagy: basic principles and relevance to disease. Annu Rev Pathol","DOI":"10.1146\/annurev.pathol.2.010506.091842"},{"key":"802_CR112","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1073\/pnas.98.2.507","volume":"98","author":"BA Laffitte","year":"2001","unstructured":"Laffitte\u00a0BA, Repa\u00a0JJ, Joseph\u00a0SB, et\u00a0al. (2001) LXRs control lipid-inducible expression of the apolipoprotein E gene in macrophages and adipocytes. Proc Natl Acad Sci USA 98:507\u2013512","journal-title":"Proc Natl Acad Sci USA"},{"key":"802_CR113","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.bbadis.2004.11.016","volume":"1740","author":"T Langmann","year":"2005","unstructured":"Langmann\u00a0T, Liebisch\u00a0G, Moehle\u00a0C, et\u00a0al. (2005) Gene expression profiling identifies retinoids as potent inducers of macrophage lipid efflux. Biochim Biophys Acta 1740:155\u2013161","journal-title":"Biochim Biophys Acta"},{"key":"802_CR114","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1038\/ncb1269","volume":"7","author":"BI Le","year":"2005","unstructured":"Le\u00a0BI, Luyet\u00a0PP, Pons\u00a0V, et\u00a0al. (2005) Endosome-to-cytosol transport of viral nucleocapsids. Nat Cell Biol 7:653\u2013664","journal-title":"Nat Cell Biol"},{"key":"802_CR115","doi-asserted-by":"crossref","first-page":"2003","DOI":"10.4049\/jimmunol.169.4.2003","volume":"169","author":"CV Le","year":"2002","unstructured":"Le\u00a0CV, Carreno\u00a0S, Moisand\u00a0A, et\u00a0al. (2002) Complement receptor 3 (CD11b\/CD18) mediates type I and type II phagocytosis during nonopsonic and opsonic phagocytosis, respectively. J Immunol 169:2003\u20132009","journal-title":"J Immunol"},{"key":"802_CR116","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1196\/annals.1329.025","volume":"1030","author":"W Li","year":"2004","unstructured":"Li\u00a0W, Xu\u00a0LH, Yuan\u00a0XM (2004) Macrophage hemoglobin scavenger receptor and ferritin accumulation in human atherosclerotic lesions. Ann NY Acad Sci 1030:196\u2013201","journal-title":"Ann NY Acad Sci"},{"key":"802_CR117","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1038\/nature01323","volume":"420","author":"P Libby","year":"2002","unstructured":"Libby\u00a0P (2002) Inflammation in atherosclerosis. Nature 420:868\u2013874","journal-title":"Nature"},{"key":"802_CR118","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/j.bbalip.2005.12.007","volume":"1761","author":"G Liebisch","year":"2006","unstructured":"Liebisch\u00a0G, Binder\u00a0M, Schifferer\u00a0R, et\u00a0al. (2006) High throughput quantification of cholesterol and cholesteryl ester by electrospray ionization tandem mass spectrometry (ESI-MS\/MS). Biochim Biophys Acta 1761:121\u2013128","journal-title":"Biochim Biophys Acta"},{"key":"802_CR119","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.bbalip.2004.09.003","volume":"1686","author":"G Liebisch","year":"2004","unstructured":"Liebisch\u00a0G, Lieser\u00a0B, Rathenberg\u00a0J, et\u00a0al. (2004) High-throughput quantification of phosphatidylcholine and sphingomyelin by electrospray ionization tandem mass spectrometry coupled with isotope correction algorithm. Biochim Biophys Acta 1686:108\u2013117","journal-title":"Biochim Biophys Acta"},{"issue":"Pt 10","key":"802_CR120","doi-asserted-by":"crossref","first-page":"1893","DOI":"10.1242\/jcs.114.10.1893","volume":"114","author":"S Lusa","year":"2001","unstructured":"Lusa\u00a0S, Blom\u00a0TS, Eskelinen\u00a0EL, et\u00a0al. (2001) Depletion of rafts in late endocytic membranes is controlled by NPC1-dependent recycling of cholesterol to the plasma membrane. J Cell Sci 114(Pt 10):1893\u20131900","journal-title":"J Cell Sci"},{"key":"802_CR121","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.bbadis.2003.09.004","volume":"1639","author":"P Maderna","year":"2003","unstructured":"Maderna\u00a0P, Godson\u00a0C (2003) Phagocytosis of apoptotic cells and the resolution of inflammation. Biochim Biophys Acta 1639:141\u2013151","journal-title":"Biochim Biophys Acta"},{"key":"802_CR122","doi-asserted-by":"crossref","first-page":"2296","DOI":"10.1161\/01.ATV.0000146266.65820.a1","volume":"24","author":"W Martinet","year":"2004","unstructured":"Martinet\u00a0W, De Bie\u00a0M, Schrijvers\u00a0DM, et\u00a0al. (2004) 7-ketocholesterol induces protein ubiquitination, myelin figure formation, and light chain 3 processing in vascular smooth muscle cells. Arterioscler ThrombArterioscler Thromb Vasc Biol 24:2296\u20132301","journal-title":"Arterioscler ThrombArterioscler Thromb Vasc Biol"},{"key":"802_CR123","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1038\/nature01250","volume":"421","author":"LO Martinez","year":"2003","unstructured":"Martinez\u00a0LO, Jacquet\u00a0S, Esteve\u00a0JP, et\u00a0al. (2003) Ectopic beta-chain of ATP synthase is an apolipoprotein A-I receptor in hepatic HDL endocytosis. Nature 421:75\u201379","journal-title":"Nature"},{"key":"802_CR124","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1161\/01.RES.83.11.1097","volume":"83","author":"N Marx","year":"1998","unstructured":"Marx\u00a0N, Schonbeck\u00a0U, Lazar\u00a0MA, et\u00a0al. (1998a) Peroxisome proliferator-activated receptor gamma activators inhibit gene expression and migration in human vascular smooth muscle cells. Circ Res 83:1097\u20131103","journal-title":"Circ Res"},{"key":"802_CR125","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0002-9440(10)65540-X","volume":"153","author":"N Marx","year":"1998","unstructured":"Marx\u00a0N, Sukhova\u00a0G, Murphy\u00a0C, et\u00a0al. (1998b) Macrophages in human atheroma contain PPARgamma: differentiation-dependent peroxisomal proliferator-activated receptor gamma(PPARgamma) expression and reduction of MMP-9 activity through PPARgamma activation in mononuclear phagocytes in vitro. Am J Pathol 153:17\u201323","journal-title":"Am J Pathol"},{"key":"802_CR126","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1126\/science.1092425","volume":"303","author":"H Matsuo","year":"2004","unstructured":"Matsuo\u00a0H, Chevallier\u00a0J, Mayran\u00a0N, et\u00a0al. (2004) Role of LBPA and Alix in multivesicular liposome formation and endosome organization. Science 303:531\u2013534","journal-title":"Science"},{"key":"802_CR127","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1006\/exmp.1995.1002","volume":"62","author":"CM McCloud","year":"1995","unstructured":"McCloud\u00a0CM, Beard T L, Kacew\u00a0S, et\u00a0al. (1995) In vivo and in vitro reversibility of chlorphentermine-induced phospholipidosis in rat alveolar macrophages. Exp Mol Pathol 62:12\u201321","journal-title":"Exp Mol Pathol"},{"key":"802_CR128","doi-asserted-by":"crossref","first-page":"9997","DOI":"10.1074\/jbc.M309992200","volume":"279","author":"Megha","year":"2004","unstructured":"Megha, London\u00a0E (2004) Ceramide selectively displaces cholesterol from ordered lipid domains (rafts): implications for lipid raft structure and function. J Biol Chem 279:9997\u201310004","journal-title":"J Biol Chem"},{"key":"802_CR129","doi-asserted-by":"crossref","first-page":"3158","DOI":"10.1074\/jbc.M007717200","volume":"276","author":"AJ Mendez","year":"2001","unstructured":"Mendez\u00a0AJ, Lin\u00a0G, Wade\u00a0DP, et\u00a0al. (2001) Membrane lipid domains distinct from cholesterol\/sphingomyelin-rich rafts are involved in the ABCA1-mediated lipid secretory pathway. J Biol Chem 276:3158\u20133166","journal-title":"J Biol Chem"},{"key":"802_CR130","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0002-9440(10)65266-2","volume":"154","author":"KD Merkel","year":"1999","unstructured":"Merkel\u00a0KD, Erdmann\u00a0JM, McHugh\u00a0KP, et\u00a0al. (1999) Tumor necrosis factor-alpha mediates orthopedic implant osteolysis. Am J Pathol 154:203\u2013210","journal-title":"Am J Pathol"},{"key":"802_CR131","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1083\/jcb.200011148","volume":"154","author":"L Michalik","year":"2001","unstructured":"Michalik\u00a0L, Desvergne\u00a0B, Tan\u00a0NS, et\u00a0al. (2001) Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR)alpha and PPARbeta mutant mice. J Cell Biol 154:799\u2013814","journal-title":"J Cell Biol"},{"key":"802_CR132","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1097\/00041433-200310000-00004","volume":"14","author":"YI Miller","year":"2003","unstructured":"Miller\u00a0YI, Chang\u00a0MK, Binder\u00a0CJ, et\u00a0al. (2003a) Oxidized low density lipoprotein and innate immune receptors. Curr Opin Lipidol 14:437\u2013445","journal-title":"Curr Opin Lipidol"},{"key":"802_CR133","doi-asserted-by":"crossref","first-page":"1561","DOI":"10.1074\/jbc.M209634200","volume":"278","author":"YI Miller","year":"2003","unstructured":"Miller\u00a0YI, Viriyakosol\u00a0S, Binder\u00a0CJ, et\u00a0al. (2003b) Minimally modified LDL binds to CD14, induces macrophage spreading via TLR4\/MD-2, and inhibits phagocytosis of apoptotic cells. J Biol Chem 278:1561\u20131568","journal-title":"J Biol Chem"},{"key":"802_CR134","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1247\/csf.27.421","volume":"27","author":"N Mizushima","year":"2002","unstructured":"Mizushima\u00a0N, Ohsumi\u00a0Y, Yoshimori\u00a0T (2002) Autophagosome formation in mammalian cells. Cell Struct Funct 27:421\u2013429","journal-title":"Cell Struct Funct"},{"key":"802_CR135","doi-asserted-by":"crossref","first-page":"7657","DOI":"10.4049\/jimmunol.176.12.7657","volume":"176","author":"K Morimoto","year":"2006","unstructured":"Morimoto\u00a0K, Janssen\u00a0WJ, Fessler\u00a0MB, et\u00a0al. (2006) Lovastatin enhances clearance of apoptotic cells (efferocytosis) with implications for chronic obstructive pulmonary disease. J Immunol 176:7657\u20137665","journal-title":"J Immunol"},{"key":"802_CR136","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1083\/jcb.200302028","volume":"161","author":"IR Nabi","year":"2003","unstructured":"Nabi\u00a0IR, Le\u00a0PU (2003) Caveolae\/raft-dependent endocytosis. J Cell Biol 161:673\u2013677","journal-title":"J Cell Biol"},{"key":"802_CR137","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/S0092-8674(00)81574-3","volume":"93","author":"L Nagy","year":"1998","unstructured":"Nagy\u00a0L, Tontonoz\u00a0P, Alvarez\u00a0JG, et\u00a0al. (1998) Oxidized LDL regulates macrophage gene expression through ligand activation of PPARgamma. Cell 93:229\u2013240","journal-title":"Cell"},{"key":"802_CR138","doi-asserted-by":"crossref","first-page":"3215","DOI":"10.1161\/01.CIR.0000134275.90823.87","volume":"109","author":"M Navab","year":"2004","unstructured":"Navab\u00a0M, Anantharamaiah\u00a0GM, Reddy\u00a0ST, et\u00a0al. (2004a) Oral D-4F causes formation of pre-beta high-density lipoprotein and improves high-density lipoprotein-mediated cholesterol efflux and reverse cholesterol transport from macrophages in apolipoprotein E-null mice. Circulation 109:3215\u20133220","journal-title":"Circulation"},{"key":"802_CR139","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1097\/00041433-200412000-00004","volume":"15","author":"M Navab","year":"2004","unstructured":"Navab\u00a0M, Anantharamaiah\u00a0GM, Reddy\u00a0ST, et\u00a0al. (2004b) Human apolipoprotein A-I and A-I mimetic peptides: potential for atherosclerosis reversal. Curr Opin Lipidol 15:645\u2013649","journal-title":"Curr Opin Lipidol"},{"key":"802_CR140","doi-asserted-by":"crossref","first-page":"18C","DOI":"10.1016\/S0002-9149(99)80466-4","volume":"76","author":"M Navab","year":"1995","unstructured":"Navab\u00a0M, Fogelman\u00a0AM, Berliner\u00a0JA, et\u00a0al. (1995) Pathogenesis of atherosclerosis. Am J Cardiol 76:18C\u201323C","journal-title":"Am J Cardiol"},{"key":"802_CR141","doi-asserted-by":"crossref","first-page":"27584","DOI":"10.1074\/jbc.M103264200","volume":"276","author":"EB Neufeld","year":"2001","unstructured":"Neufeld\u00a0EB, Remaley\u00a0AT, Demosky\u00a0SJ, et\u00a0al. (2001) Cellular localization and trafficking of the human ABCA1 transporter. J Biol Chem 276:27584\u201327590","journal-title":"J Biol Chem"},{"key":"802_CR142","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/S0962-8924(01)02107-9","volume":"11","author":"BJ Nichols","year":"2001","unstructured":"Nichols\u00a0BJ, Lippincott-Schwartz\u00a0J (2001) Endocytosis without clathrin coats. Trends Cell Biol 11:406\u2013412","journal-title":"Trends Cell Biol"},{"key":"802_CR143","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1161\/01.ATV.15.2.269","volume":"15","author":"AC Nicholson","year":"1995","unstructured":"Nicholson\u00a0AC, Frieda\u00a0S, Pearce\u00a0A, et\u00a0al. (1995) Oxidized LDL binds to CD36 on human monocyte-derived macrophages and transfected cell lines. Evidence implicating the lipid moiety of the lipoprotein as the binding site. Arterioscler ThrombArterioscler Thromb Vasc Biol 15:269\u2013275","journal-title":"Arterioscler ThrombArterioscler Thromb Vasc Biol"},{"key":"802_CR144","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1056\/NEJMoa054699","volume":"354","author":"SE Nissen","year":"2006","unstructured":"Nissen\u00a0SE, Tuzcu\u00a0EM, Brewer\u00a0HB, et\u00a0al. (2006) Effect of ACAT inhibition on the progression of coronary atherosclerosis. N Engl J Med 354:1253\u20131263","journal-title":"N Engl J Med"},{"key":"802_CR145","doi-asserted-by":"crossref","first-page":"2633","DOI":"10.4049\/jimmunol.138.8.2633","volume":"138","author":"K Ohura","year":"1987","unstructured":"Ohura\u00a0K, Katona\u00a0IM, Wahl\u00a0LM, et\u00a0al. (1987) Co-expression of chemotactic ligand receptors on human peripheral blood monocytes. J Immunol 138:2633\u20132639","journal-title":"J Immunol"},{"key":"802_CR146","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/S0005-2760(97)00126-4","volume":"1349","author":"H Ohvo","year":"1997","unstructured":"Ohvo\u00a0H, Olsio\u00a0C, Slotte\u00a0JP (1997) Effects of sphingomyelin and phosphatidylcholine degradation on cyclodextrin-mediated cholesterol efflux in cultured fibroblasts. Biochim Biophys Acta 1349:131\u2013141","journal-title":"Biochim Biophys Acta"},{"key":"802_CR147","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1161\/01.ATV.11.2.403","volume":"11","author":"JF Oram","year":"1991","unstructured":"Oram\u00a0JF, Mendez\u00a0AJ, Slotte\u00a0JP, et\u00a0al. (1991) High density lipoprotein apolipoproteins mediate removal of sterol from intracellular pools but not from plasma membranes of cholesterol-loaded fibroblasts. Arterioscler Thromb 11:403\u2013414","journal-title":"Arterioscler Thromb"},{"key":"802_CR148","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1002\/cyto.a.20229","volume":"69","author":"E Orso","year":"2006","unstructured":"Orso\u00a0E, Werner\u00a0T, Wolf\u00a0Z, et\u00a0al. (2006) Ezetimib influences the expression of raft-associated antigens in human monocytes. Cytometry A\u00a069:206\u2013208","journal-title":"Cytometry A"},{"key":"802_CR149","doi-asserted-by":"crossref","first-page":"55","DOI":"10.2174\/187152507779315796","volume":"5","author":"M Pal","year":"2007","unstructured":"Pal\u00a0M, Pillarisetti\u00a0S (2007) HDL elevators and mimetics\u2014emerging therapies for atherosclerosis. Cardiovasc Hematol Agents Med Chem 5:55\u201366","journal-title":"Cardiovasc Hematol Agents Med Chem"},{"key":"802_CR150","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1172\/JCI118853","volume":"98","author":"W Palinski","year":"1996","unstructured":"Palinski\u00a0W, Horkko\u00a0S, Miller\u00a0E, et\u00a0al. (1996) Cloning of monoclonal autoantibodies to epitopes of oxidized lipoproteins from apolipoprotein E-deficient mice. Demonstration of epitopes of oxidized low density lipoprotein in human plasma. J Clin Invest 98:800\u2013814","journal-title":"J Clin Invest"},{"key":"802_CR151","doi-asserted-by":"crossref","first-page":"1372","DOI":"10.1073\/pnas.86.4.1372","volume":"86","author":"W Palinski","year":"1989","unstructured":"Palinski\u00a0W, Rosenfeld\u00a0ME, Yla-Herttuala\u00a0S, et\u00a0al. (1989) Low density lipoprotein undergoes oxidative modification in vivo. Proc Natl Acad Sci USA 86:1372\u20131376","journal-title":"Proc Natl Acad Sci USA"},{"key":"802_CR152","first-page":"91","volume":"43","author":"R Panchagnula","year":"2000","unstructured":"Panchagnula\u00a0R, Britto\u00a0C, Vinod\u00a0J, et\u00a0al. (2000) Wolman's disease\u2014a case report. Indian J Pathol Microbiol 43:91\u201392","journal-title":"Indian J Pathol Microbiol"},{"key":"802_CR153","doi-asserted-by":"crossref","first-page":"9741","DOI":"10.1073\/pnas.87.24.9741","volume":"87","author":"S Parthasarathy","year":"1990","unstructured":"Parthasarathy\u00a0S, Barnett\u00a0J (1990) Phospholipase A2 activity of low density lipoprotein: evidence for an intrinsic phospholipase A2 activity of apoprotein B-100. Proc Natl Acad Sci USA 87:9741\u20139745","journal-title":"Proc Natl Acad Sci USA"},{"key":"802_CR154","doi-asserted-by":"crossref","first-page":"3000","DOI":"10.1073\/pnas.82.9.3000","volume":"82","author":"S Parthasarathy","year":"1985","unstructured":"Parthasarathy\u00a0S, Steinbrecher\u00a0UP, Barnett\u00a0J, et\u00a0al. (1985) Essential role of phospholipase A2 activity in endothelial cell-induced modification of low density lipoprotein. Proc Natl Acad Sci USA 82:3000\u20133004","journal-title":"Proc Natl Acad Sci USA"},{"key":"802_CR155","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1161\/01.CIR.101.3.235","volume":"10","author":"V Pasceri","year":"2000","unstructured":"Pasceri\u00a0V, Wu\u00a0HD, Willerson\u00a0JT, et\u00a0al. (2000) Modulation of vascular inflammation in vitro and in vivo by peroxisome proliferator-activated receptor-gamma activators. Circulation 10:235\u2013238","journal-title":"Circulation"},{"key":"802_CR156","doi-asserted-by":"crossref","first-page":"2527","DOI":"10.1182\/blood.V74.7.2527.2527","volume":"74","author":"B Passlick","year":"1989","unstructured":"Passlick\u00a0B, Flieger\u00a0D, Ziegler-Heitbrock\u00a0HW (1989) Identification and characterization of a\u00a0novel monocyte subpopulation in human peripheral blood. Blood 74:2527\u20132534","journal-title":"Blood"},{"key":"802_CR157","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/0022-5193(70)90111-6","volume":"29","author":"S Patton","year":"1970","unstructured":"Patton\u00a0S (1970) Correlative relationship of cholesterol and sphingomyelin in cell membranes. J Theor Biol 29:489\u2013491","journal-title":"J Theor Biol"},{"key":"802_CR158","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1016\/0962-8924(94)90086-8","volume":"4","author":"PG Pentchev","year":"1994","unstructured":"Pentchev\u00a0PG, Blanchette-Mackie\u00a0EJ, Dawidowicz\u00a0EA (1994) The NP-C gene: a\u00a0key to pathways of intracellular cholesterol transport. Trends Cell Biol 4:365\u2013369","journal-title":"Trends Cell Biol"},{"key":"802_CR159","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/S0005-2760(98)00145-3","volume":"1436","author":"DK Perry","year":"1998","unstructured":"Perry\u00a0DK, Hannun\u00a0YA (1998) The role of ceramide in cell signaling. Biochim Biophys Acta 1436:233\u2013243","journal-title":"Biochim Biophys Acta"},{"key":"802_CR160","doi-asserted-by":"crossref","first-page":"27307","DOI":"10.1074\/jbc.272.43.27307","volume":"272","author":"JM Peters","year":"1997","unstructured":"Peters\u00a0JM, Hennuyer\u00a0N, Staels\u00a0B, et\u00a0al. (1997) Alterations in lipoprotein metabolism in peroxisome proliferator-activated receptor alpha-deficient mice. J Biol Chem 272:27307\u201327312","journal-title":"J Biol Chem"},{"key":"802_CR161","doi-asserted-by":"crossref","first-page":"3153","DOI":"10.1002\/1521-4141(200111)31:11<3153::AID-IMMU3153>3.0.CO;2-0","volume":"31","author":"A Pfeiffer","year":"2001","unstructured":"Pfeiffer\u00a0A, Bottcher\u00a0A, Orso\u00a0E, et\u00a0al. (2001) Lipopolysaccharide and ceramide docking to CD14 provokes ligand-specific receptor clustering in rafts. Eur J Immunol 31:3153\u20133164","journal-title":"Eur J Immunol"},{"key":"802_CR162","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1016\/j.tcb.2004.09.016","volume":"14","author":"FJ Pixley","year":"2004","unstructured":"Pixley\u00a0FJ, Stanley\u00a0ER (2004) CSF-1 regulation of the wandering macrophage: complexity in action. Trends Cell Biol 14:628\u2013638","journal-title":"Trends Cell Biol"},{"key":"802_CR163","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1097\/00041433-200110000-00006","volume":"12","author":"J Plutzky","year":"2001","unstructured":"Plutzky\u00a0J (2001) Peroxisome proliferator-activated receptors in endothelial cell biology. Curr Opin Lipidol 12:511\u2013518","journal-title":"Curr Opin Lipidol"},{"key":"802_CR164","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1016\/S0022-2275(20)36967-4","volume":"34","author":"MI Porn","year":"1993","unstructured":"Porn\u00a0MI, Ares\u00a0MP, Slotte\u00a0JP (1993) Degradation of plasma membrane phosphatidylcholine appears not to affect the cellular cholesterol distribution. J Lipid Res 34:1385\u20131392","journal-title":"J Lipid Res"},{"key":"802_CR165","doi-asserted-by":"crossref","first-page":"20961","DOI":"10.1074\/jbc.M300304200","volume":"278","author":"V Puri","year":"2003","unstructured":"Puri\u00a0V, Jefferson\u00a0JR, Singh\u00a0RD, et\u00a0al. (2003) Sphingolipid storage induces accumulation of intracellular cholesterol by stimulating SREBP-1 cleavage. J Biol Chem 278:20961\u201320970","journal-title":"J Biol Chem"},{"key":"802_CR166","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1038\/14084","volume":"1","author":"V Puri","year":"1999","unstructured":"Puri\u00a0V, Watanabe\u00a0R, Dominguez\u00a0M, et\u00a0al. (1999) Cholesterol modulates membrane traffic along the endocytic pathway in sphingolipid-storage diseases. Nat Cell Biol 1:386\u2013388","journal-title":"Nat Cell Biol"},{"key":"802_CR167","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/0041-008X(89)90054-9","volume":"97","author":"MJ Reasor","year":"1989","unstructured":"Reasor\u00a0MJ (1989) A\u00a0review of the biology and toxicologic implications of the induction of lysosomal lamellar bodies by drugs. Toxicol Appl Pharmacol 97:47\u201356","journal-title":"Toxicol Appl Pharmacol"},{"key":"802_CR168","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1038\/34178","volume":"391","author":"M Ricote","year":"1998","unstructured":"Ricote\u00a0M, Li\u00a0AC, Willson\u00a0TM, et\u00a0al. (1998) The peroxisome proliferator-activated receptor-gamma is a\u00a0negative regulator of macrophage activation. Nature 391:79\u201382","journal-title":"Nature"},{"issue":"Pt 20","key":"802_CR169","doi-asserted-by":"crossref","first-page":"4215","DOI":"10.1242\/jcs.03191","volume":"119","author":"H Robenek","year":"2006","unstructured":"Robenek\u00a0H, Hofnagel\u00a0O, Buers\u00a0I, et\u00a0al. (2006) Adipophilin-enriched domains in the ER membrane are sites of lipid droplet biogenesis. J Cell Sci 119(Pt 20):4215\u20134224","journal-title":"J Cell Sci"},{"key":"802_CR170","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1161\/01.ATV.15.5.683","volume":"15","author":"G Rogler","year":"1995","unstructured":"Rogler\u00a0G, Trumbach\u00a0B, Klima\u00a0B, et\u00a0al. (1995) HDL-mediated efflux of intracellular cholesterol is impaired in fibroblasts from Tangier disease patients. Arterioscler Thromb Vasc Biol 15:683\u2013690","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"802_CR171","doi-asserted-by":"crossref","first-page":"1437","DOI":"10.1161\/01.ATV.16.12.1437","volume":"16","author":"G Rothe","year":"1996","unstructured":"Rothe\u00a0G, Gabriel\u00a0H, Kovacs\u00a0E, et\u00a0al. (1996) Peripheral blood mononuclear phagocyte subpopulations as cellular markers in hypercholesterolemia. Arterioscler Thromb Vasc Biol 16:1437\u20131447","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"802_CR172","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/S0021-9150(99)00061-1","volume":"144","author":"G Rothe","year":"1999","unstructured":"Rothe\u00a0G, Herr A\u00a0S, Stohr\u00a0J, et\u00a0al. (1999) A\u00a0more mature phenotype of blood mononuclear phagocytes is induced by fluvastatin treatment in hypercholesterolemic patients with coronary heart disease. Atherosclerosis 144:251\u2013261","journal-title":"Atherosclerosis"},{"key":"802_CR173","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.bcp.2003.09.014","volume":"67","author":"T Rubic","year":"2004","unstructured":"Rubic\u00a0T, Trottmann\u00a0M, Lorenz\u00a0RL (2004) Stimulation of CD36 and the key effector of reverse cholesterol transport ATP-binding cassette A1 in monocytoid cells by niacin. Biochem Pharmacol 67:411\u2013419","journal-title":"Biochem Pharmacol"},{"key":"802_CR174","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/0005-2760(76)90189-2","volume":"424","author":"T Sakurada","year":"1976","unstructured":"Sakurada\u00a0T, Orimo\u00a0H, Okabe\u00a0H, et\u00a0al. (1976) Purification and properties of cholesterol ester hydrolase from human aortic intima and media. Biochim Biophys Acta 424:204\u2013212","journal-title":"Biochim Biophys Acta"},{"key":"802_CR175","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1016\/0140-6736(92)90926-T","volume":"339","author":"JT Salonen","year":"1992","unstructured":"Salonen\u00a0JT, Yla-Herttuala\u00a0S, Yamamoto\u00a0R, et\u00a0al. (1992) Autoantibody against oxidised LDL and progression of carotid atherosclerosis. Lancet 339:883\u2013887","journal-title":"Lancet"},{"key":"802_CR176","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/S0047-6374(99)00011-1","volume":"107","author":"H Sano","year":"1999","unstructured":"Sano\u00a0H, Nagai\u00a0R, Matsumoto\u00a0K, et\u00a0al. (1999) Receptors for proteins modified by advanced glycation end products (AGE)\u2014their functional role in atherosclerosis. Mech Ageing Dev 107:333\u2013346","journal-title":"Mech Ageing Dev"},{"key":"802_CR177","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1089\/ars.2007.1576","volume":"9","author":"DJ Schaer","year":"2007","unstructured":"Schaer\u00a0DJ, Alayash\u00a0AI, Buehler\u00a0PW (2007) Gating the radical hemoglobin to macrophages: the anti-inflammatory role of CD163, a\u00a0scavenger receptor. Antioxid Redox Signal 9:991\u2013999","journal-title":"Antioxid Redox Signal"},{"key":"802_CR178","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1016\/j.bbalip.2007.04.011","volume":"1771","author":"R Schifferer","year":"2007","unstructured":"Schifferer\u00a0R, Liebisch\u00a0G, Bandulik\u00a0S, et\u00a0al. (2007) ApoA-I induces a\u00a0preferential efflux of monounsaturated phosphatidylcholine and medium chain sphingomyelin species from a\u00a0cellular pool distinct from HDL(3) mediated phospholipid efflux. Biochim Biophys Acta 1771:853\u2013863","journal-title":"Biochim Biophys Acta"},{"key":"802_CR179","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1097\/00005373-199805000-00001","volume":"44","author":"C Schinkel","year":"1998","unstructured":"Schinkel\u00a0C, Sendtner\u00a0R, Zimmer\u00a0S, et\u00a0al. (1998) Functional analysis of monocyte subsets in surgical sepsis. J Trauma 44:743\u2013748","journal-title":"J Trauma"},{"issue":"Suppl 3","key":"802_CR180","first-page":"68","volume":"34","author":"G Schmitz","year":"1996","unstructured":"Schmitz\u00a0G, Becker\u00a0A, Aslanidis\u00a0C (1996) ACAT\/CEH and ACEH\/LAL: two key enzymes in hepatic cellular cholesterol homeostasis and their involvement in genetic disorders. Z Gastroenterol 34(Suppl 3):68\u201372","journal-title":"Z Gastroenterol"},{"key":"802_CR181","doi-asserted-by":"crossref","unstructured":"Schmitz\u00a0G, Ecker\u00a0J (2007) The opposing effects of n-3 and n-6 fatty acids. Prog Lipid Res","DOI":"10.1016\/j.plipres.2007.12.004"},{"key":"802_CR182","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1089\/ars.2007.1663","volume":"9","author":"G Schmitz","year":"2007","unstructured":"Schmitz\u00a0G, Grandl\u00a0M (2007) Role of redox regulation and lipid rafts in macrophages during Ox-LDL-mediated foam cell formation. Antioxid Redox Signal 9:1499\u20131518","journal-title":"Antioxid Redox Signal"},{"key":"802_CR183","doi-asserted-by":"crossref","first-page":"1539","DOI":"10.1016\/S0022-2275(20)41642-6","volume":"32","author":"G Schmitz","year":"1991","unstructured":"Schmitz\u00a0G, Muller\u00a0G (1991) Structure and function of lamellar bodies, lipid-protein complexes involved in storage and secretion of cellular lipids. J Lipid Res 32:1539\u20131570","journal-title":"J Lipid Res"},{"key":"802_CR184","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1097\/00041433-200210000-00007","volume":"13","author":"G Schmitz","year":"2002","unstructured":"Schmitz\u00a0G, Orso\u00a0E (2002) CD14 signalling in lipid rafts: new ligands and co-receptors. Curr Opin Lipidol 13:513\u2013521","journal-title":"Curr Opin Lipidol"},{"key":"802_CR185","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/j.cardiores.2006.09.005","volume":"73","author":"DM Schrijvers","year":"2007","unstructured":"Schrijvers\u00a0DM, De Meyer\u00a0GR, Herman\u00a0AG, et\u00a0al. (2007) Phagocytosis in atherosclerosis: Molecular mechanisms and implications for plaque progression and stability. Cardiovasc Res 73:470\u2013480","journal-title":"Cardiovasc Res"},{"key":"802_CR186","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1007\/s10545-007-0632-9","volume":"30","author":"EH Schuchman","year":"2007","unstructured":"Schuchman\u00a0EH (2007) The pathogenesis and treatment of acid sphingomyelinase-deficient Niemann\u2013Pick disease. J Inherit Metab Dis 30:654\u2013663","journal-title":"J Inherit Metab Dis"},{"key":"802_CR187","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1084\/jem.172.2.547","volume":"172","author":"PS Seifert","year":"1990","unstructured":"Seifert\u00a0PS, Hugo\u00a0F, Tranum-Jensen\u00a0J, et\u00a0al. (1990) Isolation and characterization of a\u00a0complement-activating lipid extracted from human atherosclerotic lesions. J Exp Med 172:547\u2013557","journal-title":"J Exp Med"},{"key":"802_CR188","doi-asserted-by":"crossref","first-page":"414","DOI":"10.1196\/annals.1351.039","volume":"1069","author":"B Seriolo","year":"2006","unstructured":"Seriolo\u00a0B, Paolino\u00a0S, Sulli\u00a0A, et\u00a0al. (2006) Effects of anti-TNF-alpha treatment on lipid profile in patients with active rheumatoid arthritis. Ann NY Acad Sci 1069:414\u2013419","journal-title":"Ann NY Acad Sci"},{"issue":"Pt 1","key":"802_CR189","first-page":"120","volume":"130","author":"M Sevin","year":"2007","unstructured":"Sevin\u00a0M, Lesca\u00a0G, Baumann\u00a0N, et\u00a0al. (2007) The adult form of Niemann\u2013Pick disease type C. Brain 130(Pt 1):120\u2013133","journal-title":"Brain"},{"key":"802_CR190","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1016\/S0163-7827(01)00010-8","volume":"40","author":"H Shimano","year":"2001","unstructured":"Shimano\u00a0H (2001) Sterol regulatory element-binding proteins (SREBPs): transcriptional regulators of lipid synthetic genes. Prog Lipid Res 40:439\u2013452","journal-title":"Prog Lipid Res"},{"key":"802_CR191","doi-asserted-by":"crossref","unstructured":"Sigruener\u00a0A, Buechler\u00a0C, Bared\u00a0SM, et\u00a0al. (2007) E-LDL upregulates TOSO expression and enhances the survival of human macrophages. Biochem Biophys Res Commun","DOI":"10.1016\/j.bbrc.2007.05.169"},{"key":"802_CR192","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0962-8924(03)00033-3","volume":"13","author":"DJ Sillence","year":"2003","unstructured":"Sillence\u00a0DJ, Platt\u00a0FM (2003) Storage diseases: new insights into sphingolipid functions. Trends Cell Biol 13:195\u2013203","journal-title":"Trends Cell Biol"},{"key":"802_CR193","first-page":"109","volume":"123","author":"N Simionescu","year":"1986","unstructured":"Simionescu\u00a0N, Vasile\u00a0E, Lupu\u00a0F, et\u00a0al. (1986) Prelesional events in atherogenesis. Accumulation of extracellular cholesterol-rich liposomes in the arterial intima and cardiac valves of the hyperlipidemic rabbit. Am J Pathol 123:109\u2013125","journal-title":"Am J Pathol"},{"key":"802_CR194","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/S0962-8924(00)01847-X","volume":"10","author":"K Simons","year":"2000","unstructured":"Simons\u00a0K, Gruenberg\u00a0J (2000) Jamming the endosomal system: lipid rafts and lysosomal storage diseases. Trends Cell Biol 10:459\u2013462","journal-title":"Trends Cell Biol"},{"key":"802_CR195","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1042\/bj2500653","volume":"250","author":"JP Slotte","year":"1988","unstructured":"Slotte\u00a0JP, Bierman\u00a0EL (1988) Depletion of plasma-membrane sphingomyelin rapidly alters the distribution of cholesterol between plasma membranes and intracellular cholesterol pools in cultured fibroblasts. Biochem J 250:653\u2013658","journal-title":"Biochem J"},{"key":"802_CR196","doi-asserted-by":"crossref","first-page":"e851","DOI":"10.1371\/journal.pone.0000851","volume":"2","author":"K Sobo","year":"2007","unstructured":"Sobo\u00a0K, Le\u00a0BI, Luyet P P, et\u00a0al. (2007) Late endosomal cholesterol accumulation leads to impaired intra-endosomal trafficking. PLoS ONE 2:e851","journal-title":"PLoS ONE"},{"key":"802_CR197","doi-asserted-by":"crossref","first-page":"n20","DOI":"10.1016\/j.amjcard.2007.08.009","volume":"100","author":"DL Sprecher","year":"2007","unstructured":"Sprecher\u00a0DL (2007) Lipids, lipoproteins, and peroxisome proliferator activated receptor-delta. Am J Cardiol 100:n20\u2013n24","journal-title":"Am J Cardiol"},{"key":"802_CR198","doi-asserted-by":"crossref","first-page":"20963","DOI":"10.1074\/jbc.272.34.20963","volume":"272","author":"D Steinberg","year":"1997","unstructured":"Steinberg\u00a0D (1997) Low density lipoprotein oxidation and its pathobiological significance. J Biol Chem 272:20963\u201320966","journal-title":"J Biol Chem"},{"key":"802_CR199","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1056\/NEJM198901053200122","volume":"320","author":"D Steinberg","year":"1989","unstructured":"Steinberg\u00a0D, Parthasarathy\u00a0S, Carew\u00a0TE, et\u00a0al. (1989) Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity. N Engl J Med 320:915\u2013924","journal-title":"N Engl J Med"},{"key":"802_CR200","doi-asserted-by":"crossref","first-page":"15216","DOI":"10.1016\/S0021-9258(19)84812-3","volume":"264","author":"UP Steinbrecher","year":"1989","unstructured":"Steinbrecher\u00a0UP, Lougheed\u00a0M, Kwan\u00a0WC, et\u00a0al. (1989) Recognition of oxidized low density lipoprotein by the scavenger receptor of macrophages results from derivatization of apolipoprotein B by products of fatty acid peroxidation. J Biol Chem 264:15216\u201315223","journal-title":"J Biol Chem"},{"key":"802_CR201","doi-asserted-by":"crossref","first-page":"3883","DOI":"10.1073\/pnas.81.12.3883","volume":"81","author":"UP Steinbrecher","year":"1984","unstructured":"Steinbrecher\u00a0UP, Parthasarathy\u00a0S, Leake\u00a0DS, et\u00a0al. (1984) Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids. Proc Natl Acad Sci USA 81:3883\u20133887","journal-title":"Proc Natl Acad Sci USA"},{"key":"802_CR202","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1097\/00041433-199412000-00005","volume":"5","author":"R Stocker","year":"1994","unstructured":"Stocker\u00a0R (1994) Lipoprotein oxidation: mechanistic aspects, methodological approaches and clinical relevance. Curr Opin Lipidol 5:422\u2013433","journal-title":"Curr Opin Lipidol"},{"key":"802_CR203","doi-asserted-by":"crossref","first-page":"1424","DOI":"10.1161\/01.ATV.18.9.1424","volume":"18","author":"J Stohr","year":"1998","unstructured":"Stohr\u00a0J, Schindler\u00a0G, Rothe\u00a0G, et\u00a0al. (1998) Enhanced upregulation of the Fc gamma receptor IIIa (CD16a) during in vitro differentiation of ApoE4\/4 monocytes. Arterioscler Thromb Vasc Biol 18:1424\u20131432","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"802_CR204","doi-asserted-by":"crossref","first-page":"6775","DOI":"10.1073\/pnas.96.12.6775","volume":"96","author":"A Subtil","year":"1999","unstructured":"Subtil\u00a0A, Gaidarov\u00a0I, Kobylarz\u00a0K, et\u00a0al. (1999) Acute cholesterol depletion inhibits clathrin-coated pit budding. Proc Natl Acad Sci USA 96:6775\u20136780","journal-title":"Proc Natl Acad Sci USA"},{"key":"802_CR205","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1161\/hc3601.093987","volume":"104","author":"T Suzuki","year":"2001","unstructured":"Suzuki\u00a0T, Kopia\u00a0G, Hayashi\u00a0S, et\u00a0al. (2001) Stent-based delivery of sirolimus reduces neointimal formation in a\u00a0porcine coronary model. Circulation 104:1188\u20131193","journal-title":"Circulation"},{"issue":"Pt 1","key":"802_CR206","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1042\/bj3580079","volume":"358","author":"D Sviridov","year":"2001","unstructured":"Sviridov\u00a0D, Fidge\u00a0N, Beaumier-Gallon\u00a0G, et\u00a0al. (2001) Apolipoprotein A-I stimulates the transport of intracellular cholesterol to cell-surface cholesterol-rich domains (caveolae). Biochem J 358(Pt 1):79\u201386","journal-title":"Biochem J"},{"key":"802_CR207","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1002\/jlb.47.3.206","volume":"47","author":"G Szabo","year":"1990","unstructured":"Szabo\u00a0G, Miller-Graziano\u00a0CL, Wu\u00a0JY, et\u00a0al. (1990) Differential tumor necrosis factor production by human monocyte subsets. J Leukoc Biol 47:206\u2013216","journal-title":"J Leukoc Biol"},{"key":"802_CR208","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/S1388-1981(00)00146-3","volume":"1529","author":"I Tabas","year":"2000","unstructured":"Tabas\u00a0I (2000) Cholesterol and phospholipid metabolism in macrophages. Biochim Biophys Acta 1529:164\u2013174","journal-title":"Biochim Biophys Acta"},{"key":"802_CR209","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1007\/s007950200023","volume":"35","author":"K Takahashi","year":"2002","unstructured":"Takahashi\u00a0K, Takeya\u00a0M, Sakashita\u00a0N (2002) Multifunctional roles of macrophages in the development and progression of atherosclerosis in humans and experimental animals. Med Electron Microsc 35:179\u2013203","journal-title":"Med Electron Microsc"},{"key":"802_CR210","doi-asserted-by":"crossref","unstructured":"Taketa\u00a0K, Matsumura\u00a0T, Yano\u00a0M, et\u00a0al. (2008) Ox-LDL activates PPARalpha and PPARgamma through MAPK-dependent COX-2 expression in macrophages. J Biol Chem","DOI":"10.1016\/S1567-5688(09)70366-6"},{"key":"802_CR211","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1161\/01.CIR.95.1.76","volume":"95","author":"O Tamai","year":"1997","unstructured":"Tamai\u00a0O, Matsuoka\u00a0H, Itabe\u00a0H, et\u00a0al. (1997) Single LDL apheresis improves endothelium-dependent vasodilatation in hypercholesterolemic humans. Circulation 95:76\u201382","journal-title":"Circulation"},{"issue":"24","key":"802_CR212","doi-asserted-by":"crossref","first-page":"3263","DOI":"10.1101\/gad.207501","volume":"15","author":"NS Tan","year":"2001","unstructured":"Tan\u00a0NS, Michalik\u00a0L, Noy\u00a0N, et\u00a0al. (2001) Critical roles of PPAR beta\/delta in keratinocyte response to inflammation. Genes Dev 15(24):3263\u20133277","journal-title":"Genes Dev"},{"key":"802_CR213","doi-asserted-by":"crossref","first-page":"26167","DOI":"10.1074\/jbc.M311591200","volume":"279","author":"VD te","year":"2004","unstructured":"te Vruchte D, Lloyd-Evans\u00a0E, Veldman\u00a0RJ, et\u00a0al. (2004) Accumulation of glycosphingolipids in Niemann\u2013Pick C disease disrupts endosomal transport. J Biol Chem 279:26167\u201326175","journal-title":"J Biol Chem"},{"key":"802_CR214","doi-asserted-by":"crossref","first-page":"638","DOI":"10.1038\/nrg1122","volume":"4","author":"SL Teitelbaum","year":"2003","unstructured":"Teitelbaum\u00a0SL, Ross\u00a0FP (2003) Genetic regulation of osteoclast development and function. Nat Rev Genet 4:638\u2013649","journal-title":"Nat Rev Genet"},{"key":"802_CR215","doi-asserted-by":"crossref","first-page":"25481","DOI":"10.1074\/jbc.270.43.25481","volume":"270","author":"LW Tjoelker","year":"1995","unstructured":"Tjoelker\u00a0LW, Eberhardt\u00a0C, Unger\u00a0J, et\u00a0al. (1995) Plasma platelet-activating factor acetylhydrolase is a\u00a0secreted phospholipase A2 with a\u00a0catalytic triad. J Biol Chem 270:25481\u201325487","journal-title":"J Biol Chem"},{"key":"802_CR216","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/S0092-8674(00)81575-5","volume":"93","author":"P Tontonoz","year":"1998","unstructured":"Tontonoz\u00a0P, Nagy\u00a0L, Alvarez\u00a0JG, et\u00a0al. (1998) PPARgamma promotes monocyte\/macrophage differentiation and uptake of oxidized LDL. Cell 93:241\u2013252","journal-title":"Cell"},{"key":"802_CR217","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1161\/01.ATV.18.3.369","volume":"18","author":"M Torzewski","year":"1998","unstructured":"Torzewski\u00a0M, Klouche\u00a0M, Hock\u00a0J, et\u00a0al. (1998) Immunohistochemical demonstration of enzymatically modified human LDL and its colocalization with the terminal complement complex in the early atherosclerotic lesion. Arterioscler Thromb Vasc Biol 18:369\u2013378","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"802_CR218","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1515\/CCLM.2006.259","volume":"44","author":"M Torzewski","year":"2006","unstructured":"Torzewski\u00a0M, Lackner\u00a0KJ (2006) Initiation and progression of atherosclerosis\u2014enzymatic or oxidative modification of low-density lipoprotein? Clin Chem Lab Med 44:1389\u20131394","journal-title":"Clin Chem Lab Med"},{"key":"802_CR219","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1161\/01.ATV.21.1.95","volume":"21","author":"S Tsimikas","year":"2001","unstructured":"Tsimikas\u00a0S, Palinski\u00a0W, Witztum\u00a0JL (2001) Circulating autoantibodies to oxidized LDL correlate with arterial accumulation and depletion of oxidized LDL in LDL receptor-deficient mice. Arterioscler Thromb Vasc Biol 21:95\u2013100","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"802_CR220","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1006\/bbrc.2001.5575","volume":"287","author":"K Tsukamoto","year":"2001","unstructured":"Tsukamoto\u00a0K, Hirano\u00a0K, Tsujii\u00a0K, et\u00a0al. (2001) ATP-binding cassette transporter-1 induces rearrangement of actin cytoskeletons possibly through Cdc42\/N-WASP. Biochem Biophys Res Commun 287:757\u2013765","journal-title":"Biochem Biophys Res Commun"},{"issue":"Pt 3","key":"802_CR221","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1042\/BJ20050460","volume":"391","author":"S Vainio","year":"2005","unstructured":"Vainio\u00a0S, Bykov\u00a0I, Hermansson\u00a0M, et\u00a0al. (2005) Defective insulin receptor activation and altered lipid rafts in Niemann\u2013Pick type C disease hepatocytes. Biochem J 391(Pt 3):465\u2013472","journal-title":"Biochem J"},{"key":"802_CR222","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1097\/01.mol.0000183943.20277.26","volume":"16","author":"TJ Berkel van","year":"2005","unstructured":"van Berkel\u00a0TJ, Out\u00a0R, Hoekstra\u00a0M, et\u00a0al. (2005) Scavenger receptors: friend or foe in atherosclerosis? Curr Opin Lipidol 16:525\u2013535","journal-title":"Curr Opin Lipidol"},{"key":"802_CR223","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1007\/BF01797928","volume":"14","author":"MT Vanier","year":"1991","unstructured":"Vanier\u00a0MT, Pentchev\u00a0P, Rodriguez-Lafrasse\u00a0C, et\u00a0al. (1991) Niemann\u2013Pick disease type C: an update. J Inherit Metab Dis 14:580\u2013595","journal-title":"J Inherit Metab Dis"},{"key":"802_CR224","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1016\/j.jacc.2006.09.047","volume":"49","author":"S Verheye","year":"2007","unstructured":"Verheye\u00a0S, Martinet\u00a0W, Kockx M M, et\u00a0al. (2007) Selective clearance of macrophages in atherosclerotic plaques by autophagy. J Am Coll Cardiol 49:706\u2013715","journal-title":"J Am Coll Cardiol"},{"key":"802_CR225","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1006\/bbrc.1994.2742","volume":"205","author":"M Walter","year":"1994","unstructured":"Walter\u00a0M, Gerdes\u00a0U, Seedorf\u00a0U, et\u00a0al. (1994) The high density lipoprotein- and apolipoprotein A-I-induced mobilization of cellular cholesterol is impaired in fibroblasts from Tangier disease subjects. Biochem Biophys Res Commun 205:850\u2013856","journal-title":"Biochem Biophys Res Commun"},{"key":"802_CR226","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S0014-5793(99)01521-5","volume":"462","author":"X Wang","year":"1999","unstructured":"Wang\u00a0X, Reape T J, Li\u00a0X, et\u00a0al. (1999) Induced expression of adipophilin mRNA in human macrophages stimulated with oxidized low-density lipoprotein and in atherosclerotic lesions. FEBS Lett 462:145\u2013150","journal-title":"FEBS Lett"},{"key":"802_CR227","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1111\/j.1600-0749.2005.00289.x","volume":"19","author":"ML Wei","year":"2006","unstructured":"Wei\u00a0ML (2006) Hermansky-Pudlak syndrome: a\u00a0disease of protein trafficking and organelle function. Pigment Cell Res 19:19\u201342","journal-title":"Pigment Cell Res"},{"key":"802_CR228","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1161\/01.ATV.15.5.551","volume":"15","author":"KJ Williams","year":"1995","unstructured":"Williams\u00a0KJ, Tabas\u00a0I (1995) The response-to-retention hypothesis of early atherogenesis. Arterioscler Thromb Vasc Biol 15:551\u2013561","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"802_CR229","doi-asserted-by":"crossref","first-page":"40121","DOI":"10.1074\/jbc.M305193200","volume":"278","author":"SR Witting","year":"2003","unstructured":"Witting\u00a0SR, Maiorano\u00a0JN, Davidson\u00a0WS (2003) Ceramide enhances cholesterol efflux to apolipoprotein A-I by increasing the cell surface presence of ATP-binding cassette transporter A1. J Biol Chem 278:40121\u201340127","journal-title":"J Biol Chem"},{"key":"802_CR230","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1002\/cyto.a.20238","volume":"69","author":"Z Wolf","year":"2006","unstructured":"Wolf\u00a0Z, Orso\u00a0E, Werner\u00a0T, et\u00a0al. (2006) A\u00a0flow cytometric screening test for detergent-resistant surface antigens in monocytes. Cytometry A\u00a069:192\u2013195","journal-title":"Cytometry A"},{"key":"802_CR231","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1002\/cyto.a.20403","volume":"71","author":"Z Wolf","year":"2007","unstructured":"Wolf\u00a0Z, Orso\u00a0E, Werner\u00a0T, et\u00a0al. (2007) Monocyte cholesterol homeostasis correlates with the presence of detergent resistant membrane microdomains. Cytometry A\u00a071:486\u2013494","journal-title":"Cytometry A"},{"key":"802_CR232","doi-asserted-by":"crossref","first-page":"33540","DOI":"10.1074\/jbc.M104776200","volume":"276","author":"X Xu","year":"2001","unstructured":"Xu\u00a0X, Bittman\u00a0R, Duportail\u00a0G, et\u00a0al. (2001) Effect of the structure of natural sterols and sphingolipids on the formation of ordered sphingolipid\/sterol domains (rafts). Comparison of cholesterol to plant, fungal, and disease-associated sterols and comparison of sphingomyelin, cerebrosides, and ceramide. J Biol Chem 276:33540\u201333546","journal-title":"J Biol Chem"},{"key":"802_CR233","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1021\/bi992543v","volume":"39","author":"X Xu","year":"2000","unstructured":"Xu\u00a0X, London\u00a0E (2000) The effect of sterol structure on membrane lipid domains reveals how cholesterol can induce lipid domain formation. Biochemistry 39:843\u2013849","journal-title":"Biochemistry"},{"issue":"Pt 1","key":"802_CR234","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1042\/bj20031811","volume":"379","author":"SJ Yeaman","year":"2004","unstructured":"Yeaman\u00a0SJ (2004) Hormone-sensitive lipase\u2014new roles for an old enzyme. Biochem J 379(Pt 1):11\u201322","journal-title":"Biochem J"},{"key":"802_CR235","doi-asserted-by":"crossref","first-page":"1086","DOI":"10.1172\/JCI114271","volume":"84","author":"S Yla-Herttuala","year":"1989","unstructured":"Yla-Herttuala\u00a0S, Palinski\u00a0W, Rosenfeld M E, et\u00a0al. (1989) Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man. J Clin Invest 84:1086\u20131095","journal-title":"J Clin Invest"},{"key":"802_CR236","first-page":"1","volume":"32","author":"M Zembala","year":"1986","unstructured":"Zembala\u00a0M, Pryjma\u00a0J, Uracz\u00a0W, et\u00a0al. (1986) Regulation of human lymphocyte response in vitro by monocytes and their subsets. Folia Biol (Praha) 32:1\u201311","journal-title":"Folia Biol (Praha)"},{"key":"802_CR237","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.4049\/jimmunol.133.3.1293","volume":"133","author":"M Zembala","year":"1984","unstructured":"Zembala\u00a0M, Uracz\u00a0W, Ruggiero\u00a0I, et\u00a0al. (1984) Isolation and functional characteristics of FcR+ and FcR- human monocyte subsets. J Immunol 133:1293\u20131299","journal-title":"J Immunol"},{"key":"802_CR238","doi-asserted-by":"crossref","first-page":"45931","DOI":"10.1074\/jbc.M307722200","volume":"278","author":"Y Zeng","year":"2003","unstructured":"Zeng\u00a0Y, Tao\u00a0N, Chung\u00a0KN, et\u00a0al. (2003) Endocytosis of oxidized low density lipoprotein through scavenger receptor CD36 utilizes a\u00a0lipid raft pathway that does not require caveolin-1. J Biol Chem 278:45931\u201345936","journal-title":"J Biol Chem"},{"key":"802_CR239","doi-asserted-by":"crossref","first-page":"10002","DOI":"10.1074\/jbc.C300024200","volume":"278","author":"X Zha","year":"2003","unstructured":"Zha\u00a0X, Gauthier\u00a0A, Genest\u00a0J, et\u00a0al. (2003) Secretory vesicular transport from the Golgi is altered during ATP-binding cassette protein A1 (ABCA1)-mediated cholesterol efflux. J Biol Chem 278:10002\u201310005","journal-title":"J Biol Chem"},{"key":"802_CR240","doi-asserted-by":"crossref","first-page":"2053","DOI":"10.1002\/eji.1830230902","volume":"23","author":"HW Ziegler-Heitbrock","year":"1993","unstructured":"Ziegler-Heitbrock\u00a0HW, Fingerle\u00a0G, Strobel\u00a0M, et\u00a0al. (1993) The novel subset of CD14+\/CD16+ blood monocytes exhibits features of tissue macrophages. Eur J Immunol 23:2053\u20132058","journal-title":"Eur J Immunol"}],"container-title":["Reviews of Physiology Biochemistry and Pharmacology"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/112_2008_802.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,17]],"date-time":"2023-05-17T20:47:46Z","timestamp":1684356466000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/112_2008_802"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008]]},"ISBN":["9783540776031","9783540776048"],"references-count":239,"URL":"https:\/\/doi.org\/10.1007\/112_2008_802","relation":{},"subject":[],"published":{"date-parts":[[2008]]}}}