{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T05:24:06Z","timestamp":1778563446493,"version":"3.51.4"},"publisher-location":"Cham","reference-count":160,"publisher":"Springer International Publishing","isbn-type":[{"value":"9783319463698","type":"print"},{"value":"9783319463711","type":"electronic"}],"license":[{"start":{"date-parts":[[2016,1,1]],"date-time":"2016-01-01T00:00:00Z","timestamp":1451606400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016]]},"DOI":"10.1007\/164_2016_33","type":"book-chapter","created":{"date-parts":[[2016,10,18]],"date-time":"2016-10-18T09:12:46Z","timestamp":1476781966000},"page":"285-310","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":7,"title":["Molecular Control of Actin Dynamics In Vivo: Insights from Drosophila"],"prefix":"10.1007","author":[{"given":"Lena","family":"Br\u00fcser","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sven","family":"Bogdan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2016,10,19]]},"reference":[{"key":"33_CR1","doi-asserted-by":"publisher","first-page":"1047","DOI":"10.1016\/S0092-8674(00)00208-7","volume":"103","author":"J Bai","year":"2000","unstructured":"Bai J, Uehara Y, Montell DJ (2000) Regulation of invasive cell behavior by taiman, a Drosophila protein related to AIB1, a steroid receptor coactivator amplified in breast cancer. Cell 103:1047\u20131058","journal-title":"Cell"},{"key":"33_CR2","doi-asserted-by":"publisher","first-page":"R1082","DOI":"10.1016\/j.cub.2008.09.011","volume":"18","author":"R Bastock","year":"2008","unstructured":"Bastock R, St Johnston D (2008) Drosophila oogenesis. Curr Biol 18:R1082\u2013R1087","journal-title":"Curr Biol"},{"key":"33_CR3","doi-asserted-by":"publisher","first-page":"R231","DOI":"10.1016\/j.cub.2011.01.071","volume":"21","author":"R Bastock","year":"2011","unstructured":"Bastock R, St Johnston D (2011) Oogenesis: matrix revolutions. Curr Biol 21:R231\u2013R233","journal-title":"Curr Biol"},{"key":"33_CR4","doi-asserted-by":"publisher","first-page":"1325","DOI":"10.1083\/jcb.142.5.1325","volume":"142","author":"JE Bear","year":"1998","unstructured":"Bear JE, Rawls JF, Saxe CL 3rd (1998) SCAR, a WASP-related protein, isolated as a suppressor of receptor defects in late Dictyostelium development. J Cell Biol 142:1325\u20131335","journal-title":"J Cell Biol"},{"key":"33_CR5","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1016\/S0925-4773(01)00615-3","volume":"111","author":"S Beccari","year":"2002","unstructured":"Beccari S, Teixeira L, Rorth P (2002) The JAK\/STAT pathway is required for border cell migration during Drosophila oogenesis. Mech Dev 111:115\u2013123","journal-title":"Mech Dev"},{"key":"33_CR6","doi-asserted-by":"publisher","first-page":"11","DOI":"10.4161\/21541248.2014.973765","volume":"5","author":"M Bechtold","year":"2014","unstructured":"Bechtold M, Schultz J, Bogdan S (2014) FHOD proteins in actin dynamics\u2014a formin\u2019 class of its own. Small GTPases 5:11","journal-title":"Small GTPases"},{"key":"33_CR7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1083\/jcb.152.1.1","volume":"152","author":"S Ben-Yaacov","year":"2001","unstructured":"Ben-Yaacov S, Le Borgne R, Abramson I, Schweisguth F, Schejter ED (2001) Wasp, the Drosophila Wiskott-Aldrich syndrome gene homologue, is required for cell fate decisions mediated by Notch signaling. J Cell Biol 152:1\u201313","journal-title":"J Cell Biol"},{"key":"33_CR8","doi-asserted-by":"publisher","first-page":"1303","DOI":"10.1242\/jcs.022269","volume":"121","author":"S Berger","year":"2008","unstructured":"Berger S, Schafer G, Kesper DA, Holz A, Eriksson T, Palmer RH, Beck L, Klambt C, Renkawitz-Pohl R, Onel SF (2008) WASP and SCAR have distinct roles in activating the Arp2\/3 complex during myoblast fusion. J Cell Sci 121:1303\u20131313","journal-title":"J Cell Sci"},{"key":"33_CR9","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1038\/nrg1503","volume":"6","author":"E Bier","year":"2005","unstructured":"Bier E (2005) Drosophila, the golden bug, emerges as a tool for human genetics. Nat Rev Genet 6:9\u201323","journal-title":"Nat Rev Genet"},{"key":"33_CR10","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1016\/j.devcel.2011.12.003","volume":"22","author":"D Bilder","year":"2012","unstructured":"Bilder D, Haigo SL (2012) Expanding the morphogenetic repertoire: perspectives from the Drosophila egg. Dev Cell 22:12\u201323","journal-title":"Dev Cell"},{"key":"33_CR11","doi-asserted-by":"publisher","first-page":"4427","DOI":"10.1242\/dev.00663","volume":"130","author":"S Bogdan","year":"2003","unstructured":"Bogdan S, Klambt C (2003) Kette regulates actin dynamics and genetically interacts with Wave and Wasp. Development 130:4427\u20134437","journal-title":"Development"},{"key":"33_CR12","doi-asserted-by":"publisher","first-page":"977","DOI":"10.1038\/ncb1305","volume":"7","author":"S Bogdan","year":"2005","unstructured":"Bogdan S, Stephan R, Lobke C, Mertens A, Klambt C (2005) Abi activates WASP to promote sensory organ development. Nat Cell Biol 7:977\u2013984","journal-title":"Nat Cell Biol"},{"key":"33_CR13","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1016\/j.devcel.2006.02.004","volume":"10","author":"L Borghese","year":"2006","unstructured":"Borghese L, Fletcher G, Mathieu J, Atzberger A, Eades WC, Cagan RL, Rorth P (2006) Systematic analysis of the transcriptional switch inducing migration of border cells. Dev Cell 10:497\u2013508","journal-title":"Dev Cell"},{"key":"33_CR14","doi-asserted-by":"publisher","first-page":"4278","DOI":"10.1182\/blood-2007-06-096875","volume":"110","author":"G Bouma","year":"2007","unstructured":"Bouma G, Burns S, Thrasher AJ (2007) Impaired T-cell priming in vivo resulting from dysfunction of WASp-deficient dendritic cells. Blood 110:4278\u20134284","journal-title":"Blood"},{"key":"33_CR15","doi-asserted-by":"publisher","first-page":"2492","DOI":"10.1182\/blood-2011-03-340265","volume":"118","author":"G Bouma","year":"2011","unstructured":"Bouma G, Mendoza-Naranjo A, Blundell MP, de Falco E, Parsley KL, Burns SO, Thrasher AJ (2011) Cytoskeletal remodeling mediated by WASp in dendritic cells is necessary for normal immune synapse formation and T-cell priming. Blood 118:2492\u20132501","journal-title":"Blood"},{"key":"33_CR157","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1242\/dev.118.2.401","volume":"118","author":"AH Brand","year":"1993","unstructured":"Brand AH, Perrimon N (1993) Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development 118:401\u2013415","journal-title":"Development"},{"key":"33_CR16","doi-asserted-by":"publisher","first-page":"604","DOI":"10.1242\/jcs.179325","volume":"129","author":"K Brinkmann","year":"2016","unstructured":"Brinkmann K, Winterhoff M, Onel SF, Schultz J, Faix J, Bogdan S (2016) WHAMY is a novel actin polymerase promoting myoblast fusion, macrophage cell motility and sensory organ development in Drosophila. J Cell Sci 129:604\u2013620","journal-title":"J Cell Sci"},{"key":"33_CR17","doi-asserted-by":"publisher","first-page":"73","DOI":"10.1016\/j.devcel.2004.06.007","volume":"7","author":"K Bruckner","year":"2004","unstructured":"Bruckner K, Kockel L, Duchek P, Luque CM, Rorth P, Perrimon N (2004) The PDGF\/VEGF receptor controls blood cell survival in Drosophila. Dev Cell 7:73\u201384","journal-title":"Dev Cell"},{"key":"33_CR18","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1146\/annurev-biophys-051309-103849","volume":"39","author":"B Bugyi","year":"2010","unstructured":"Bugyi B, Carlier MF (2010) Control of actin filament treadmilling in cell motility. Annu Rev Biophys 39:449\u2013470","journal-title":"Annu Rev Biophys"},{"key":"33_CR19","doi-asserted-by":"publisher","first-page":"3006","DOI":"10.1016\/j.bbamcr.2015.07.021","volume":"1853","author":"R Caceres","year":"2015","unstructured":"Caceres R, Abou-Ghali M, Plastino J (2015) Reconstituting the actin cytoskeleton at or near surfaces in vitro. Biochim Biophys Acta 1853:3006\u20133014","journal-title":"Biochim Biophys Acta"},{"key":"33_CR20","doi-asserted-by":"publisher","first-page":"1146","DOI":"10.1016\/j.cell.2014.03.045","volume":"157","author":"D Cai","year":"2014","unstructured":"Cai D, Chen SC, Prasad M, He L, Wang X, Choesmel-Cadamuro V, Sawyer JK, Danuser G, Montell DJ (2014) Mechanical feedback through E-cadherin promotes direction sensing during collective cell migration. Cell 157:1146\u20131159","journal-title":"Cell"},{"key":"33_CR21","doi-asserted-by":"publisher","first-page":"1520","DOI":"10.1016\/j.cub.2015.04.020","volume":"25","author":"JM Cameron","year":"2015","unstructured":"Cameron JM, Gabrielsen M, Chim YH, Munro J, McGhee EJ, Sumpton D, Eaton P, Anderson KI, Yin HB, Olson MF (2015) Polarized cell motility induces hydrogen peroxide to inhibit cofilin via cysteine oxidation. Curr Biol 25:1520\u20131525","journal-title":"Curr Biol"},{"key":"33_CR155","doi-asserted-by":"publisher","first-page":"148","DOI":"10.1016\/j.cell.2008.05.032","volume":"134","author":"KG Campellone","year":"2008","unstructured":"Campellone KG, Webb NJ, Znameroski EA, Welch MD (2008) WHAMM is an Arp2\/3 complex activator that binds microtubules and functions in ER to Golgi transport. Cell 134:148\u2013161","journal-title":"Cell"},{"key":"33_CR22","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1038\/nrm2867","volume":"11","author":"KG Campellone","year":"2010","unstructured":"Campellone KG, Welch MD (2010) A nucleator arms race: cellular control of actin assembly. Nat Rev Mol Cell Biol 11:237\u2013251","journal-title":"Nat Rev Mol Cell Biol"},{"key":"33_CR23","doi-asserted-by":"publisher","first-page":"1731","DOI":"10.1073\/pnas.0409376102","volume":"102","author":"G Cestra","year":"2005","unstructured":"Cestra G, Toomre D, Chang S, De Camilli P (2005) The Abl\/Arg substrate ArgBP2\/nArgBP2 coordinates the function of multiple regulatory mechanisms converging on the actin cytoskeleton. Proc Natl Acad Sci U S A 102:1731\u20131736","journal-title":"Proc Natl Acad Sci U S A"},{"key":"33_CR24","doi-asserted-by":"publisher","first-page":"10","DOI":"10.1016\/j.gde.2015.01.003","volume":"32","author":"M Cetera","year":"2015","unstructured":"Cetera M, Horne-Badovinac S (2015) Round and round gets you somewhere: collective cell migration and planar polarity in elongating Drosophila egg chambers. Curr Opin Genet Dev 32:10\u201315","journal-title":"Curr Opin Genet Dev"},{"key":"33_CR25","doi-asserted-by":"publisher","first-page":"5511","DOI":"10.1038\/ncomms6511","volume":"5","author":"M Cetera","year":"2014","unstructured":"Cetera M, Ramirez-San Juan GR, Oakes PW, Lewellyn L, Fairchild MJ, Tanentzapf G, Gardel ML, Horne-Badovinac S (2014) Epithelial rotation promotes the global alignment of contractile actin bundles during Drosophila egg chamber elongation. Nat Commun 5:5511","journal-title":"Nat Commun"},{"key":"33_CR26","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1016\/B978-0-12-385891-7.00010-6","volume":"68","author":"EH Chen","year":"2011","unstructured":"Chen EH (2011) Invasive podosomes and myoblast fusion. Curr Top Membr 68:235\u2013258","journal-title":"Curr Top Membr"},{"key":"33_CR27","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1038\/nature09623","volume":"468","author":"Z Chen","year":"2010","unstructured":"Chen Z, Borek D, Padrick SB, Gomez TS, Metlagel Z, Ismail AM, Umetani J, Billadeau DD, Otwinowski Z, Rosen MK (2010) Structure and control of the actin regulatory WAVE complex. Nature 468:533\u2013538","journal-title":"Nature"},{"key":"33_CR28","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1016\/j.cell.2013.11.048","volume":"156","author":"B Chen","year":"2014","unstructured":"Chen B, Brinkmann K, Chen Z, Pak CW, Liao Y, Shi S, Henry L, Grishin NV, Bogdan S, Rosen MK (2014a) The WAVE regulatory complex links diverse receptors to the actin cytoskeleton. Cell 156:195\u2013207","journal-title":"Cell"},{"key":"33_CR29","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1016\/j.devcel.2014.08.001","volume":"30","author":"XJ Chen","year":"2014","unstructured":"Chen XJ, Squarr AJ, Stephan R, Chen B, Higgins TE, Barry DJ, Martin MC, Rosen MK, Bogdan S, Way M (2014b) Ena\/VASP proteins cooperate with the WAVE complex to regulate the actin cytoskeleton. Dev Cell 30:569\u2013584","journal-title":"Dev Cell"},{"key":"33_CR30","doi-asserted-by":"publisher","first-page":"865","DOI":"10.1016\/S0092-8674(02)00676-1","volume":"108","author":"NK Cho","year":"2002","unstructured":"Cho NK, Keyes L, Johnson E, Heller J, Ryner L, Karim F, Krasnow MA (2002) Developmental control of blood cell migration by the Drosophila VEGF pathway. Cell 108:865\u2013876","journal-title":"Cell"},{"key":"33_CR31","doi-asserted-by":"publisher","first-page":"97","DOI":"10.1016\/S0955-0674(99)00062-9","volume":"12","author":"JA Cooper","year":"2000","unstructured":"Cooper JA, Schafer DA (2000) Control of actin assembly and disassembly at filament ends. Curr Opin Cell Biol 12:97\u2013103","journal-title":"Curr Opin Cell Biol"},{"key":"33_CR32","doi-asserted-by":"publisher","first-page":"15424","DOI":"10.1073\/pnas.0706881104","volume":"104","author":"V Cotta-de-Almeida","year":"2007","unstructured":"Cotta-de-Almeida V, Westerberg L, Maillard MH, Onaldi D, Wachtel H, Meelu P, Chung UI, Xavier R, Alt FW, Snapper SB (2007) Wiskott Aldrich syndrome protein (WASP) and N-WASP are critical for T cell development. Proc Natl Acad Sci U S A 104:15424\u201315429","journal-title":"Proc Natl Acad Sci U S A"},{"key":"33_CR33","doi-asserted-by":"publisher","first-page":"471","DOI":"10.1083\/jcb.201003135","volume":"191","author":"MV D\u2019Ambrosio","year":"2010","unstructured":"D\u2019Ambrosio MV, Vale RD (2010) A whole genome RNAi screen of Drosophila S2 cell spreading performed using automated computational image analysis. J Cell Biol 191:471\u2013478","journal-title":"J Cell Biol"},{"key":"33_CR34","doi-asserted-by":"crossref","unstructured":"Derry JM, Ochs HD, Francke U (1994) Isolation of a novel gene mutated in Wiskott-Aldrich syndrome. Cell 79:following 922","DOI":"10.1016\/0092-8674(94)90528-2"},{"key":"33_CR35","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1038\/85886","volume":"27","author":"K Devriendt","year":"2001","unstructured":"Devriendt K, Kim AS, Mathijs G, Frints SG, Schwartz M, Van Den Oord JJ, Verhoef GE, Boogaerts MA, Fryns JP, You D, Rosen MK, Vandenberghe P (2001) Constitutively activating mutation in WASP causes X-linked severe congenital neutropenia. Nat Genet 27:313\u2013317","journal-title":"Nat Genet"},{"key":"33_CR158","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1038\/nature05954","volume":"448","author":"G Dietzl","year":"2007","unstructured":"Dietzl G, Chen D, Schnorrer F, Su KC, Barinova Y, Fellner M, Gasser B, Kinsey K, Oppel S, Scheiblauer S et al (2007) A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila. Nature 448:151\u2013156","journal-title":"Nature"},{"key":"33_CR36","doi-asserted-by":"publisher","first-page":"1358","DOI":"10.1038\/ncomms2347","volume":"4","author":"B Dong","year":"2013","unstructured":"Dong B, Kakihara K, Otani T, Wada H, Hayashi S (2013) Rab9 and retromer regulate retrograde trafficking of luminal protein required for epithelial tube length control. Nat Commun 4:1358","journal-title":"Nat Commun"},{"key":"33_CR37","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1126\/science.291.5501.131","volume":"291","author":"P Duchek","year":"2001","unstructured":"Duchek P, Rorth P (2001) Guidance of cell migration by EGF receptor signaling during Drosophila oogenesis. Science 291:131\u2013133","journal-title":"Science"},{"key":"33_CR38","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1016\/S0092-8674(01)00502-5","volume":"107","author":"P Duchek","year":"2001","unstructured":"Duchek P, Somogyi K, Jekely G, Beccari S, Rorth P (2001) Guidance of cell migration by the Drosophila PDGF\/VEGF receptor. Cell 107:17\u201326","journal-title":"Cell"},{"key":"33_CR39","doi-asserted-by":"publisher","first-page":"790","DOI":"10.1038\/nature00859","volume":"418","author":"S Eden","year":"2002","unstructured":"Eden S, Rohatgi R, Podtelejnikov AV, Mann M, Kirschner MW (2002) Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck. Nature 418:790\u2013793","journal-title":"Nature"},{"key":"33_CR40","doi-asserted-by":"publisher","first-page":"709","DOI":"10.1038\/cdd.2012.166","volume":"20","author":"IR Evans","year":"2013","unstructured":"Evans IR, Ghai PA, Urbancic V, Tan KL, Wood W (2013) SCAR\/WAVE-mediated processing of engulfed apoptotic corpses is essential for effective macrophage migration in Drosophila. Cell Death Differ 20:709\u2013720","journal-title":"Cell Death Differ"},{"key":"33_CR41","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1016\/j.ceb.2010.10.007","volume":"23","author":"EN Firat-Karalar","year":"2011","unstructured":"Firat-Karalar EN, Welch MD (2011) New mechanisms and functions of actin nucleation. Curr Opin Cell Biol 23:4\u201313","journal-title":"Curr Opin Cell Biol"},{"key":"33_CR42","doi-asserted-by":"publisher","first-page":"1429","DOI":"10.1016\/j.cub.2009.07.058","volume":"19","author":"R Fricke","year":"2009","unstructured":"Fricke R, Gohl C, Dharmalingam E, Grevelhorster A, Zahedi B, Harden N, Kessels M, Qualmann B, Bogdan S (2009) Drosophila Cip4\/Toca-1 integrates membrane trafficking and actin dynamics through WASP and SCAR\/WAVE. Curr Biol 19:1429\u20131437","journal-title":"Curr Biol"},{"key":"33_CR43","first-page":"99","volume":"7","author":"B Frugtniet","year":"2015","unstructured":"Frugtniet B, Jiang WG, Martin TA (2015) Role of the WASP and WAVE family proteins in breast cancer invasion and metastasis. Breast Cancer (Dove Med Press) 7:99\u2013109","journal-title":"Breast Cancer (Dove Med Press)"},{"key":"33_CR44","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1038\/ncb848","volume":"4","author":"TA Fulga","year":"2002","unstructured":"Fulga TA, Rorth P (2002) Invasive cell migration is initiated by guided growth of long cellular extensions. Nat Cell Biol 4:715\u2013719","journal-title":"Nat Cell Biol"},{"key":"33_CR45","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0074923","volume":"8","author":"M Gardberg","year":"2013","unstructured":"Gardberg M, Kaipio K, Lehtinen L, Mikkonen P, Heuser VD, Talvinen K, Iljin K, Kampf C, Uhlen M, Grenman R, Koivisto M, Carpen O (2013) FHOD1, a formin upregulated in epithelial-mesenchymal transition, participates in cancer cell migration and invasion. PLoS One 8, e74923","journal-title":"PLoS One"},{"key":"33_CR46","doi-asserted-by":"publisher","first-page":"213","DOI":"10.4161\/fly.21969","volume":"6","author":"J Gates","year":"2012","unstructured":"Gates J (2012) Drosophila egg chamber elongation Insights into how tissues and organs are shaped. Fly 6:213\u2013227","journal-title":"Fly"},{"key":"33_CR47","doi-asserted-by":"publisher","first-page":"536","DOI":"10.1038\/ncb0509-536","volume":"11","author":"D Godt","year":"2009","unstructured":"Godt D, Tepass U (2009) Breaking a temporal barrier: signalling crosstalk regulates the initiation of border cell migration. Nat Cell Biol 11:536\u2013538","journal-title":"Nat Cell Biol"},{"key":"33_CR48","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1016\/j.coph.2004.06.009","volume":"4","author":"NJ Goulding","year":"2004","unstructured":"Goulding NJ (2004) The molecular complexity of glucocorticoid actions in inflammation \u2013 a four-ring circus. Curr Opin Pharmacol 4:629\u2013636","journal-title":"Curr Opin Pharmacol"},{"key":"33_CR49","doi-asserted-by":"publisher","first-page":"11211","DOI":"10.1073\/pnas.1116065109","volume":"109","author":"Y Gruenbaum-Cohen","year":"2012","unstructured":"Gruenbaum-Cohen Y, Harel I, Umansky KB, Tzahor E, Snapper SB, Shilo BZ, Schejter ED (2012) The actin regulator N-WASp is required for muscle-cell fusion in mice. Proc Natl Acad Sci U S A 109:11211\u201311216","journal-title":"Proc Natl Acad Sci U S A"},{"key":"33_CR50","doi-asserted-by":"publisher","first-page":"4957","DOI":"10.1529\/biophysj.107.120345","volume":"94","author":"MG Gustafsson","year":"2008","unstructured":"Gustafsson MG, Shao L, Carlton PM, Wang CJ, Golubovskaya IN, Cande WZ, Agard DA, Sedat JW (2008) Three-dimensional resolution doubling in wide-field fluorescence microscopy by structured illumination. Biophys J 94:4957\u20134970","journal-title":"Biophys J"},{"key":"33_CR51","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1038\/nmeth.1567","volume":"8","author":"D Hadjieconomou","year":"2011","unstructured":"Hadjieconomou D, Rotkopf S, Alexandre C, Bell DM, Dickson BJ, Salecker I (2011) Flybow: genetic multicolor cell labeling for neural circuit analysis in Drosophila melanogaster. Nat Methods 8:260\u2013266","journal-title":"Nat Methods"},{"key":"33_CR52","doi-asserted-by":"publisher","first-page":"1071","DOI":"10.1126\/science.1199424","volume":"331","author":"SL Haigo","year":"2011","unstructured":"Haigo SL, Bilder D (2011) Global tissue revolutions in a morphogenetic movement controlling elongation. Science 331:1071\u20131074","journal-title":"Science"},{"key":"33_CR53","doi-asserted-by":"publisher","first-page":"1551","DOI":"10.1242\/dev.057653","volume":"138","author":"S Haralalka","year":"2011","unstructured":"Haralalka S, Shelton C, Cartwright HN, Katzfey E, Janzen E, Abmayr SM (2011) Asymmetric Mbc, active Rac1 and F-actin foci in the fusion-competent myoblasts during myoblast fusion in Drosophila. Development 138:1551\u20131562","journal-title":"Development"},{"key":"33_CR54","doi-asserted-by":"publisher","first-page":"612","DOI":"10.1016\/j.gde.2011.08.011","volume":"21","author":"L He","year":"2011","unstructured":"He L, Wang X, Montell DJ (2011) Shining light on Drosophila oogenesis: live imaging of egg development. Curr Opin Genet Dev 21:612\u2013619","journal-title":"Curr Opin Genet Dev"},{"key":"33_CR55","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1002\/dvdy.20286","volume":"232","author":"S Horne-Badovinac","year":"2005","unstructured":"Horne-Badovinac S, Bilder D (2005) Mass transit: epithelial morphogenesis in the Drosophila egg chamber. Dev Dyn 232:559\u2013574","journal-title":"Dev Dyn"},{"key":"33_CR56","doi-asserted-by":"publisher","first-page":"1243","DOI":"10.1042\/BST0331243","volume":"33","author":"N Ibarra","year":"2005","unstructured":"Ibarra N, Pollitt A, Insall RH (2005) Regulation of actin assembly by SCAR\/WAVE proteins. Biochem Soc Trans 33:1243\u20131246","journal-title":"Biochem Soc Trans"},{"key":"33_CR57","doi-asserted-by":"publisher","first-page":"427","DOI":"10.1097\/00130832-200312000-00003","volume":"3","author":"K Imai","year":"2003","unstructured":"Imai K, Nonoyama S, Ochs HD (2003) WASP (Wiskott-Aldrich syndrome protein) gene mutations and phenotype. Curr Opin Allergy Clin Immunol 3:427\u2013436","journal-title":"Curr Opin Allergy Clin Immunol"},{"key":"33_CR58","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1038\/ncb1863","volume":"11","author":"AC Jang","year":"2009","unstructured":"Jang AC, Chang YC, Bai J, Montell D (2009) Border-cell migration requires integration of spatial and temporal signals by the BTB protein Abrupt. Nat Cell Biol 11:569\u2013579","journal-title":"Nat Cell Biol"},{"key":"33_CR59","doi-asserted-by":"publisher","first-page":"4010","DOI":"10.1182\/blood-2003-05-1592","volume":"104","author":"Y Jin","year":"2004","unstructured":"Jin Y, Mazza C, Christie JR, Giliani S, Fiorini M, Mella P, Gandellini F, Stewart DM, Zhu Q, Nelson DL, Notarangelo LD, Ochs HD (2004) Mutations of the Wiskott-Aldrich syndrome protein (WASP): hotspots, effect on transcription, and translation and phenotype\/genotype correlation. Blood 104:4010\u20134019","journal-title":"Blood"},{"key":"33_CR60","doi-asserted-by":"publisher","first-page":"633","DOI":"10.1128\/MCB.06212-11","volume":"32","author":"S Jurmeister","year":"2012","unstructured":"Jurmeister S, Baumann M, Balwierz A, Keklikoglou I, Ward A, Uhlmann S, Zhang JD, Wiemann S, Sahin O (2012) MicroRNA-200c represses migration and invasion of breast cancer cells by targeting actin-regulatory proteins FHOD1 and PPM1F. Mol Cell Biol 32:633\u2013651","journal-title":"Mol Cell Biol"},{"key":"33_CR61","doi-asserted-by":"publisher","first-page":"472","DOI":"10.1242\/dev.102913","volume":"141","author":"O Kanca","year":"2014","unstructured":"Kanca O, Caussinus E, Denes AS, Percival-Smith A, Affolter M (2014) Raeppli: a whole-tissue labeling tool for live imaging of Drosophila development. Development 141:472\u2013480","journal-title":"Development"},{"key":"33_CR62","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1186\/1475-4924-2-27","volume":"2","author":"AA Kiger","year":"2003","unstructured":"Kiger AA, Baum B, Jones S, Jones MR, Coulson A, Echeverri C, Perrimon N (2003) A functional genomic analysis of cell morphology using RNA interference. J Biol 2:27","journal-title":"J Biol"},{"key":"33_CR63","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1186\/1756-0500-5-88","volume":"5","author":"M Kollmar","year":"2012","unstructured":"Kollmar M, Lbik D, Enge S (2012) Evolution of the eukaryotic ARP2\/3 activators of the WASP family: WASP, WAVE, WASH, and WHAMM, and the proposed new family members WAWH and WAML. BMC Res Notes 5:88","journal-title":"BMC Res Notes"},{"key":"33_CR64","doi-asserted-by":"publisher","first-page":"14449","DOI":"10.1073\/pnas.1107666108","volume":"108","author":"V Koronakis","year":"2011","unstructured":"Koronakis V, Hume PJ, Humphreys D, Liu T, Horning O, Jensen ON, McGhie EJ (2011) WAVE regulatory complex activation by cooperating GTPases Arf and Rac1. Proc Natl Acad Sci U S A 108:14449\u201314454","journal-title":"Proc Natl Acad Sci U S A"},{"key":"33_CR65","doi-asserted-by":"publisher","first-page":"577","DOI":"10.1038\/nrm3861","volume":"15","author":"M Krause","year":"2014","unstructured":"Krause M, Gautreau A (2014) Steering cell migration: lamellipodium dynamics and the regulation of directional persistence. Nat Rev Mol Cell Biol 15:577\u2013590","journal-title":"Nat Rev Mol Cell Biol"},{"key":"33_CR66","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1038\/nature05650","volume":"446","author":"J Krzemien","year":"2007","unstructured":"Krzemien J, Dubois L, Makki R, Meister M, Vincent A, Crozatier M (2007) Control of blood cell homeostasis in Drosophila larvae by the posterior signalling centre. Nature 446:325\u2013328","journal-title":"Nature"},{"key":"33_CR67","doi-asserted-by":"publisher","first-page":"1867","DOI":"10.1016\/j.cub.2003.10.005","volume":"13","author":"P Kunda","year":"2003","unstructured":"Kunda P, Craig G, Dominguez V, Baum B (2003) Abi, Sra1, and Kette control the stability and localization of SCAR\/WAVE to regulate the formation of actin-based protrusions. Curr Biol 13:1867\u20131875","journal-title":"Curr Biol"},{"key":"33_CR68","doi-asserted-by":"publisher","first-page":"1366","DOI":"10.1242\/dev.101352","volume":"141","author":"U Lammel","year":"2014","unstructured":"Lammel U, Bechtold M, Risse B, Berh D, Fleige A, Bunse I, Jiang X, Klambt C, Bogdan S (2014) The Drosophila FHOD1-like formin Knittrig acts through Rok to promote stress fiber formation and directed macrophage migration during the cellular immune response. Development 141:1366\u20131380","journal-title":"Development"},{"key":"33_CR69","doi-asserted-by":"publisher","first-page":"1098","DOI":"10.1073\/pnas.0409120102","volume":"102","author":"Y Leng","year":"2005","unstructured":"Leng Y, Zhang J, Badour K, Arpaia E, Freeman S, Cheung P, Siu M, Siminovitch K (2005) Abelson-interactor-1 promotes WAVE2 membrane translocation and Abelson-mediated tyrosine phosphorylation required for WAVE2 activation. Proc Natl Acad Sci U S A 102:1098\u20131103","journal-title":"Proc Natl Acad Sci U S A"},{"key":"33_CR70","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.0030237","volume":"3","author":"EV Linardopoulou","year":"2007","unstructured":"Linardopoulou EV, Parghi SS, Friedman C, Osborn GE, Parkhurst SM, Trask BJ (2007) Human subtelomeric WASH genes encode a new subclass of the WASP family. PLoS Genet 3, e237","journal-title":"PLoS Genet"},{"key":"33_CR71","doi-asserted-by":"publisher","first-page":"2849","DOI":"10.1242\/dev.035246","volume":"136","author":"R Liu","year":"2009","unstructured":"Liu R, Abreu-Blanco MT, Barry KC, Linardopoulou EV, Osborn GE, Parkhurst SM (2009a) Wash functions downstream of Rho and links linear and branched actin nucleation factors. Development 136:2849\u20132860","journal-title":"Development"},{"key":"33_CR72","doi-asserted-by":"publisher","first-page":"R26","DOI":"10.1186\/gb-2009-10-3-r26","volume":"10","author":"T Liu","year":"2009","unstructured":"Liu T, Sims D, Baum B (2009b) Parallel RNAi screens across different cell lines identify generic and cell type-specific regulators of actin organization and cell morphology. Genome Biol 10:R26","journal-title":"Genome Biol"},{"key":"33_CR73","doi-asserted-by":"publisher","first-page":"613","DOI":"10.1038\/44183","volume":"401","author":"TP Loisel","year":"1999","unstructured":"Loisel TP, Boujemaa R, Pantaloni D, Carlier MF (1999) Reconstitution of actin-based motility of Listeria and Shigella using pure proteins. Nature 401:613\u2013616","journal-title":"Nature"},{"key":"33_CR74","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1016\/S0955-0674(99)80014-3","volume":"11","author":"LM Machesky","year":"1999","unstructured":"Machesky LM, Gould KL (1999) The Arp2\/3 complex: a multifunctional actin organizer. Curr Opin Cell Biol 11:117\u2013121","journal-title":"Curr Opin Cell Biol"},{"key":"33_CR75","doi-asserted-by":"publisher","first-page":"1347","DOI":"10.1016\/S0960-9822(98)00015-3","volume":"8","author":"LM Machesky","year":"1998","unstructured":"Machesky LM, Insall RH (1998) Scar1 and the related Wiskott-Aldrich syndrome protein, WASP, regulate the actin cytoskeleton through the Arp2\/3 complex. Curr Biol 8:1347\u20131356","journal-title":"Curr Biol"},{"key":"33_CR76","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1083\/jcb.127.1.107","volume":"127","author":"LM Machesky","year":"1994","unstructured":"Machesky LM, Atkinson SJ, Ampe C, Vandekerckhove J, Pollard TD (1994) Purification of a cortical complex containing two unconventional actins from Acanthamoeba by affinity chromatography on profilin-agarose. J Cell Biol 127:107\u2013115","journal-title":"J Cell Biol"},{"key":"33_CR77","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1084\/jem.20061338","volume":"204","author":"MH Maillard","year":"2007","unstructured":"Maillard MH, Cotta-de-Almeida V, Takeshima F, Nguyen DD, Michetti P, Nagler C, Bhan AK, Snapper SB (2007) The Wiskott-Aldrich syndrome protein is required for the function of CD4(+)CD25(+)Foxp3(+) regulatory T cells. J Exp Med 204:381\u2013391","journal-title":"J Exp Med"},{"key":"33_CR78","doi-asserted-by":"publisher","first-page":"4805","DOI":"10.1073\/pnas.0801766106","volume":"106","author":"R Markus","year":"2009","unstructured":"Markus R, Laurinyecz B, Kurucz E, Honti V, Bajusz I, Sipos B, Somogyi K, Kronhamn J, Hultmark D, Ando I (2009) Sessile hemocytes as a hematopoietic compartment in Drosophila melanogaster. Proc Natl Acad Sci U S A 106:4805\u20134809","journal-title":"Proc Natl Acad Sci U S A"},{"key":"33_CR79","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1016\/j.devcel.2007.01.016","volume":"12","author":"R Massarwa","year":"2007","unstructured":"Massarwa R, Carmon S, Shilo BZ, Schejter ED (2007) WIP\/WASp-based actin-polymerization machinery is essential for myoblast fusion in Drosophila. Dev Cell 12:557\u2013569","journal-title":"Dev Cell"},{"key":"33_CR80","first-page":"175","volume":"294","author":"JA McDonald","year":"2005","unstructured":"McDonald JA, Montell DJ (2005) Analysis of cell migration using Drosophila as a model system. Methods Mol Biol 294:175\u2013202","journal-title":"Methods Mol Biol"},{"key":"33_CR81","doi-asserted-by":"publisher","first-page":"3469","DOI":"10.1242\/dev.00574","volume":"130","author":"JA McDonald","year":"2003","unstructured":"McDonald JA, Pinheiro EM, Montell DJ (2003) PVF1, a PDGF\/VEGF homolog, is sufficient to guide border cells and interacts genetically with Taiman. Development 130:3469\u20133478","journal-title":"Development"},{"key":"33_CR82","doi-asserted-by":"publisher","first-page":"94","DOI":"10.1016\/j.ydbio.2006.04.438","volume":"296","author":"JA McDonald","year":"2006","unstructured":"McDonald JA, Pinheiro EM, Kadlec L, Schupbach T, Montell DJ (2006) Multiple EGFR ligands participate in guiding migrating border cells. Dev Biol 296:94\u2013103","journal-title":"Dev Biol"},{"key":"33_CR83","doi-asserted-by":"publisher","first-page":"1546","DOI":"10.1126\/science.1167094","volume":"322","author":"A McMahon","year":"2008","unstructured":"McMahon A, Supatto W, Fraser SE, Stathopoulos A (2008) Dynamic analyses of Drosophila gastrulation provide insights into collective cell migration. Science 322:1546\u20131550","journal-title":"Science"},{"key":"33_CR84","doi-asserted-by":"crossref","first-page":"5326","DOI":"10.1002\/j.1460-2075.1996.tb00917.x","volume":"15","author":"H Miki","year":"1996","unstructured":"Miki H, Miura K, Takenawa T (1996) N-WASP, a novel actin-depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinases. EMBO J 15:5326\u20135335","journal-title":"EMBO J"},{"key":"33_CR85","doi-asserted-by":"publisher","first-page":"3769","DOI":"10.1038\/sj.emboj.7600380","volume":"23","author":"MJ Moeller","year":"2004","unstructured":"Moeller MJ, Soofi A, Braun GS, Li X, Watzl C, Kriz W, Holzman LB (2004) Protocadherin FAT1 binds Ena\/VASP proteins and is necessary for actin dynamics and cell polarization. EMBO J 23:3769\u20133779","journal-title":"EMBO J"},{"key":"33_CR86","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1146\/annurev-biochem-060408-092949","volume":"79","author":"S Mohr","year":"2010","unstructured":"Mohr S, Bakal C, Perrimon N (2010) Genomic screening with RNAi: results and challenges. Annu Rev Biochem 79:37\u201364","journal-title":"Annu Rev Biochem"},{"key":"33_CR160","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1038\/nrm1006","volume":"4","author":"DJ Montell","year":"2003","unstructured":"Montell DJ (2003) Border-cell migration: the race is on. Nat Rev Mol Cell Bio 4:13\u201324","journal-title":"Nat Rev Mol Cell Bio"},{"key":"33_CR87","doi-asserted-by":"publisher","first-page":"51","DOI":"10.1016\/0092-8674(92)90265-E","volume":"71","author":"DJ Montell","year":"1992","unstructured":"Montell DJ, Rorth P, Spradling AC (1992) Slow border cells, a locus required for a developmentally regulated cell migration during oogenesis, encodes Drosophila C\/EBP. Cell 71:51\u201362","journal-title":"Cell"},{"key":"33_CR88","doi-asserted-by":"publisher","first-page":"631","DOI":"10.1038\/nrm3433","volume":"13","author":"DJ Montell","year":"2012","unstructured":"Montell DJ, Yoon WH, Starz-Gaiano M (2012) Group choreography: mechanisms orchestrating the collective movement of border cells. Nat Rev Mol Cell Biol 13:631\u2013645","journal-title":"Nat Rev Mol Cell Biol"},{"key":"33_CR89","doi-asserted-by":"publisher","first-page":"464","DOI":"10.1016\/j.cub.2010.01.047","volume":"20","author":"S Moreira","year":"2010","unstructured":"Moreira S, Stramer B, Evans I, Wood W, Martin P (2010) Prioritization of competing damage and developmental signals by migrating macrophages in the Drosophila embryo. Curr Biol 20:464\u2013470","journal-title":"Curr Biol"},{"key":"33_CR90","doi-asserted-by":"publisher","first-page":"795","DOI":"10.1242\/bio.20134564","volume":"2","author":"CG Moreira","year":"2013","unstructured":"Moreira CG, Jacinto A, Prag S (2013) Drosophila integrin adhesion complexes are essential for hemocyte migration in vivo. Biol Open 2:795\u2013801","journal-title":"Biol Open"},{"key":"33_CR91","doi-asserted-by":"publisher","first-page":"2347","DOI":"10.1242\/dev.055012","volume":"138","author":"P Mukherjee","year":"2011","unstructured":"Mukherjee P, Gildor B, Shilo BZ, VijayRaghavan K, Schejter ED (2011) The actin nucleator WASp is required for myoblast fusion during adult Drosophila myogenesis. Development 138:2347\u20132357","journal-title":"Development"},{"key":"33_CR92","doi-asserted-by":"publisher","first-page":"996","DOI":"10.1038\/nature08119","volume":"459","author":"P Niethammer","year":"2009","unstructured":"Niethammer P, Grabher C, Look AT, Mitchison TJ (2009) A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish. Nature 459:996\u2013999","journal-title":"Nature"},{"key":"33_CR159","doi-asserted-by":"publisher","first-page":"1089","DOI":"10.1534\/genetics.109.103630","volume":"182","author":"JQ Ni","year":"2009","unstructured":"Ni JQ, Liu LP, Binari R, Hardy R, Shim HS, Cavallaro A, Booker M, Pfeiffer BD, Markstein M, Wang H et al (2009) A Drosophila resource of transgenic RNAi lines for neurogenetics. Genetics 182:1089\u20131100","journal-title":"Genetics"},{"key":"33_CR93","doi-asserted-by":"publisher","first-page":"420","DOI":"10.1038\/ncb1125","volume":"6","author":"T Oikawa","year":"2004","unstructured":"Oikawa T, Yamaguchi H, Itoh T, Kato M, Ijuin T, Yamazaki D, Suetsugu S, Takenawa T (2004) PtdIns(3,4,5)P3 binding is necessary for WAVE2-induced formation of lamellipodia. Nat Cell Biol 6:420\u2013426","journal-title":"Nat Cell Biol"},{"key":"33_CR94","doi-asserted-by":"publisher","first-page":"295","DOI":"10.1146\/annurev-genet-120213-092218","volume":"48","author":"SM Pocha","year":"2014","unstructured":"Pocha SM, Montell DJ (2014) Cellular and molecular mechanisms of single and collective cell migrations in Drosophila: themes and variations. Annu Rev Genet 48:295\u2013318","journal-title":"Annu Rev Genet"},{"key":"33_CR95","doi-asserted-by":"publisher","first-page":"453","DOI":"10.1016\/S0092-8674(03)00120-X","volume":"112","author":"TD Pollard","year":"2003","unstructured":"Pollard TD, Borisy GG (2003) Cellular motility driven by assembly and disassembly of actin filaments. Cell 112:453\u2013465","journal-title":"Cell"},{"key":"33_CR96","doi-asserted-by":"publisher","first-page":"1208","DOI":"10.1126\/science.1175862","volume":"326","author":"TD Pollard","year":"2009","unstructured":"Pollard TD, Cooper JA (2009) Actin, a central player in cell shape and movement. Science 326:1208\u20131212","journal-title":"Science"},{"key":"33_CR97","doi-asserted-by":"publisher","first-page":"7254","DOI":"10.1038\/ncomms8254","volume":"6","author":"NS Poulter","year":"2015","unstructured":"Poulter NS, Pollitt AY, Davies A, Malinova D, Nash GB, Hannon MJ, Pikramenou Z, Rappoport JZ, Hartwig JH, Owen DM, Thrasher AJ, Watson SP, Thomas SG (2015) Platelet actin nodules are podosome-like structures dependent on Wiskott-Aldrich syndrome protein and ARP2\/3 complex. Nat Commun 6:7254","journal-title":"Nat Commun"},{"key":"33_CR98","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1038\/ncb1888","volume":"11","author":"A Rajan","year":"2009","unstructured":"Rajan A, Tien AC, Haueter CM, Schulze KL, Bellen HJ (2009) The Arp2\/3 complex and WASp are required for apical trafficking of Delta into microvilli during cell fate specification of sensory organ precursors. Nat Cell Biol 11:815\u2013824","journal-title":"Nat Cell Biol"},{"key":"33_CR99","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1016\/j.devcel.2015.05.002","volume":"33","author":"E Ramond","year":"2015","unstructured":"Ramond E, Meister M, Lemaitre B (2015) From embryo to adult: hematopoiesis along the Drosophila life cycle. Dev Cell 33:367\u2013368","journal-title":"Dev Cell"},{"key":"33_CR100","doi-asserted-by":"publisher","first-page":"424","DOI":"10.1016\/j.cub.2013.01.058","volume":"23","author":"W Razzell","year":"2013","unstructured":"Razzell W, Evans IR, Martin P, Wood W (2013) Calcium flashes orchestrate the wound inflammatory response through DUOX activation and hydrogen peroxide release. Curr Biol 23:424\u2013429","journal-title":"Curr Biol"},{"key":"33_CR101","doi-asserted-by":"publisher","first-page":"2819","DOI":"10.1182\/blood-2011-09-379412","volume":"119","author":"M Recher","year":"2012","unstructured":"Recher M, Burns SO, de la Fuente MA, Volpi S, Dahlberg C, Walter JE, Moffitt K, Mathew D, Honke N, Lang PA, Patrizi L, Falet H, Keszei M, Mizui M, Csizmadia E, Candotti F, Nadeau K, Bouma G, Delmonte OM, Frugoni F, Fomin AB, Buchbinder D, Lundequist EM, Massaad MJ, Tsokos GC, Hartwig J, Manis J, Terhorst C, Geha RS, Snapper S, Lang KS, Malley R, Westerberg L, Thrasher AJ, Notarangelo LD (2012) B cell-intrinsic deficiency of the Wiskott-Aldrich syndrome protein (WASp) causes severe abnormalities of the peripheral B-cell compartment in mice. Blood 119:2819\u20132828","journal-title":"Blood"},{"key":"33_CR102","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1003720","volume":"9","author":"JC Regan","year":"2013","unstructured":"Regan JC, Brandao AS, Leitao AB, Mantas Dias AR, Sucena E, Jacinto A, Zaidman-Remy A (2013) Steroid hormone signaling is essential to regulate innate immune cells and fight bacterial infection in Drosophila. PLoS Pathog 9, e1003720","journal-title":"PLoS Pathog"},{"key":"33_CR103","doi-asserted-by":"publisher","first-page":"1114","DOI":"10.1101\/gr.169101","volume":"11","author":"LT Reiter","year":"2001","unstructured":"Reiter LT, Potocki L, Chien S, Gribskov M, Bier E (2001) A systematic analysis of human disease-associated gene sequences in Drosophila melanogaster. Genome Res 11:1114\u20131125","journal-title":"Genome Res"},{"key":"33_CR104","doi-asserted-by":"publisher","first-page":"479","DOI":"10.1016\/j.tig.2014.08.003","volume":"30","author":"LE Rieder","year":"2014","unstructured":"Rieder LE, Larschan EN (2014) Wisdom from the fly. Trends Genet 30:479\u2013481","journal-title":"Trends Genet"},{"key":"33_CR105","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1146\/annurev.cellbio.13.1.147","volume":"13","author":"DN Robinson","year":"1997","unstructured":"Robinson DN, Cooley L (1997) Genetic analysis of the actin cytoskeleton in the Drosophila ovary. Annu Rev Cell Dev Biol 13:147\u2013170","journal-title":"Annu Rev Cell Dev Biol"},{"key":"33_CR106","doi-asserted-by":"publisher","first-page":"1079","DOI":"10.1083\/jcb.200303023","volume":"162","author":"SL Rogers","year":"2003","unstructured":"Rogers SL, Wiedemann U, Stuurman N, Vale RD (2003) Molecular requirements for actin-based lamella formation in Drosophila S2 cells. J Cell Biol 162:1079\u20131088","journal-title":"J Cell Biol"},{"key":"33_CR107","doi-asserted-by":"publisher","first-page":"221","DOI":"10.1016\/S0092-8674(00)80732-1","volume":"97","author":"R Rohatgi","year":"1999","unstructured":"Rohatgi R, Ma L, Miki H, Lopez M, Kirchhausen T, Takenawa T, Kirschner MW (1999) The interaction between N-WASP and the Arp2\/3 complex links Cdc42-dependent signals to actin assembly. Cell 97:221\u2013231","journal-title":"Cell"},{"key":"33_CR108","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1083\/jcb.201103168","volume":"194","author":"JL Rohn","year":"2011","unstructured":"Rohn JL, Sims D, Liu T, Fedorova M, Schock F, Dopie J, Vartiainen MK, Kiger AA, Perrimon N, Baum B (2011) Comparative RNAi screening identifies a conserved core metazoan actinome by phenotype. J Cell biol 194:789\u2013805","journal-title":"J Cell biol"},{"key":"33_CR109","doi-asserted-by":"publisher","first-page":"984","DOI":"10.1038\/embor.2012.149","volume":"13","author":"P Rorth","year":"2012","unstructured":"Rorth P (2012) Fellow travellers: emergent properties of collective cell migration. EMBO Rep 13:984\u2013991","journal-title":"EMBO Rep"},{"key":"33_CR110","doi-asserted-by":"publisher","first-page":"104","DOI":"10.1016\/j.semcdb.2014.03.031","volume":"28","author":"AE Rosales-Nieves","year":"2014","unstructured":"Rosales-Nieves AE, Gonzalez-Reyes A (2014) Genetics and mechanisms of ovarian cancer: parallels between Drosophila and humans. Semin Cell Dev Biol 28:104\u2013109","journal-title":"Semin Cell Dev Biol"},{"key":"33_CR111","doi-asserted-by":"publisher","first-page":"2729","DOI":"10.1242\/dev.059865","volume":"138","author":"S Rotkopf","year":"2011","unstructured":"Rotkopf S, Hamberg Y, Aigaki T, Snapper SB, Shilo BZ, Schejter ED (2011) The WASp-based actin polymerization machinery is required in somatic support cells for spermatid maturation and release. Development 138:2729\u20132739","journal-title":"Development"},{"key":"33_CR112","doi-asserted-by":"publisher","first-page":"569","DOI":"10.1016\/j.ceb.2011.07.003","volume":"23","author":"K Rottner","year":"2011","unstructured":"Rottner K, Stradal TE (2011) Actin dynamics and turnover in cell motility. Curr Opin Cell Biol 23:569\u2013578","journal-title":"Curr Opin Cell Biol"},{"key":"33_CR113","doi-asserted-by":"publisher","first-page":"42","DOI":"10.1111\/j.1524-475X.2008.00440.x","volume":"17","author":"CE Routley","year":"2009","unstructured":"Routley CE, Ashcroft GS (2009) Effect of estrogen and progesterone on macrophage activation during wound healing. Wound Repair Regen 17:42\u201350","journal-title":"Wound Repair Regen"},{"key":"33_CR114","doi-asserted-by":"publisher","first-page":"150","DOI":"10.4049\/jimmunol.1302923","volume":"193","author":"S Sadhukhan","year":"2014","unstructured":"Sadhukhan S, Sarkar K, Taylor M, Candotti F, Vyas YM (2014) Nuclear role of WASp in gene transcription is uncoupled from its ARP2\/3-dependent cytoplasmic role in actin polymerization. J Immunol 193:150\u2013160","journal-title":"J Immunol"},{"key":"33_CR115","doi-asserted-by":"publisher","first-page":"1412","DOI":"10.1242\/bio.20136619","volume":"2","author":"CJ Sampson","year":"2013","unstructured":"Sampson CJ, Amin U, Couso JP (2013) Activation of Drosophila hemocyte motility by the ecdysone hormone. Biol Open 2:1412\u20131420","journal-title":"Biol Open"},{"key":"33_CR116","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1016\/j.ejcb.2013.09.003","volume":"92","author":"M Sander","year":"2013","unstructured":"Sander M, Squarr AJ, Risse B, Jiang X, Bogdan S (2013) Drosophila pupal macrophages\u2014a versatile tool for combined ex vivo and in vivo imaging of actin dynamics at high resolution. Eur J Cell Biol 92:349\u2013354","journal-title":"Eur J Cell Biol"},{"key":"33_CR117","doi-asserted-by":"publisher","first-page":"3409","DOI":"10.1182\/blood-2014-07-587642","volume":"124","author":"K Sarkar","year":"2014","unstructured":"Sarkar K, Sadhukhan S, Han SS, Vyas YM (2014) Disruption of hSWI\/SNF complexes in T cells by WAS mutations distinguishes X-linked thrombocytopenia from Wiskott-Aldrich syndrome. Blood 124:3409\u20133419","journal-title":"Blood"},{"key":"33_CR118","doi-asserted-by":"publisher","first-page":"1013","DOI":"10.1083\/jcb.201006006","volume":"191","author":"KL Sens","year":"2010","unstructured":"Sens KL, Zhang S, Jin P, Duan R, Zhang G, Luo F, Parachini L, Chen EH (2010) An invasive podosome-like structure promotes fusion pore formation during myoblast fusion. J Cell Biol 191:1013\u20131027","journal-title":"J Cell Biol"},{"key":"33_CR119","doi-asserted-by":"publisher","first-page":"359","DOI":"10.1126\/science.1234781","volume":"340","author":"K Shilagardi","year":"2013","unstructured":"Shilagardi K, Li S, Luo F, Marikar F, Duan R, Jin P, Kim JH, Murnen K, Chen EH (2013) Actin-propelled invasive membrane protrusions promote fusogenic protein engagement during cell-cell fusion. Science 340:359\u2013363","journal-title":"Science"},{"key":"33_CR120","doi-asserted-by":"publisher","first-page":"831","DOI":"10.1016\/S0092-8674(01)00607-9","volume":"107","author":"DL Silver","year":"2001","unstructured":"Silver DL, Montell DJ (2001) Paracrine signaling through the JAK\/STAT pathway activates invasive behavior of ovarian epithelial cells in Drosophila. Cell 107:831\u2013841","journal-title":"Cell"},{"key":"33_CR121","doi-asserted-by":"publisher","first-page":"3483","DOI":"10.1242\/dev.01910","volume":"132","author":"DL Silver","year":"2005","unstructured":"Silver DL, Geisbrecht ER, Montell DJ (2005) Requirement for JAK\/STAT signaling throughout border cell migration in Drosophila. Development 132:3483\u20133492","journal-title":"Development"},{"key":"33_CR122","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1016\/S1074-7613(00)80590-7","volume":"9","author":"SB Snapper","year":"1998","unstructured":"Snapper SB, Rosen FS, Mizoguchi E, Cohen P, Khan W, Liu CH, Hagemann TL, Kwan SP, Ferrini R, Davidson L, Bhan AK, Alt FW (1998) Wiskott-Aldrich syndrome protein-deficient mice reveal a role for WASP in T but not B cell activation. Immunity 9:81\u201391","journal-title":"Immunity"},{"key":"33_CR123","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1083\/jcb.201508081","volume":"212","author":"AJ Squarr","year":"2016","unstructured":"Squarr AJ, Brinkmann K, Chen B, Steinbacher T, Ebnet K, Rosen MK, Bogdan S (2016) Fat2 acts through the WAVE regulatory complex to drive collective cell migration during tissue rotation. J Cell Biol 212:591\u2013603","journal-title":"J Cell Biol"},{"key":"33_CR124","doi-asserted-by":"publisher","first-page":"86","DOI":"10.1016\/j.gde.2003.12.001","volume":"14","author":"M Starz-Gaiano","year":"2004","unstructured":"Starz-Gaiano M, Montell DJ (2004) Genes that drive invasion and migration in Drosophila. Curr Opin Genet Dev 14:86\u201391","journal-title":"Curr Opin Genet Dev"},{"key":"33_CR125","doi-asserted-by":"publisher","first-page":"183","DOI":"10.1016\/j.mod.2007.12.002","volume":"125","author":"R Stephan","year":"2008","unstructured":"Stephan R, Grevelhorster A, Wenderdel S, Klambt C, Bogdan S (2008) Abi induces ectopic sensory organ formation by stimulating EGFR signaling. Mech Dev 125:183\u2013195","journal-title":"Mech Dev"},{"key":"33_CR126","doi-asserted-by":"publisher","first-page":"4079","DOI":"10.1091\/mbc.E11-02-0121","volume":"22","author":"R Stephan","year":"2011","unstructured":"Stephan R, Gohl C, Fleige A, Klambt C, Bogdan S (2011) Membrane-targeted WAVE mediates photoreceptor axon targeting in the absence of the WAVE complex in Drosophila. Mol Biol Cell 22:4079\u20134092","journal-title":"Mol Biol Cell"},{"key":"33_CR127","doi-asserted-by":"crossref","first-page":"5019","DOI":"10.4049\/jimmunol.162.8.5019","volume":"162","author":"DM Stewart","year":"1999","unstructured":"Stewart DM, Tian L, Nelson DL (1999) Mutations that cause the Wiskott-Aldrich syndrome impair the interaction of Wiskott-Aldrich syndrome protein (WASP) with WASP interacting protein. J Immunol 162:5019\u20135024","journal-title":"J Immunol"},{"key":"33_CR128","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1083\/jcb.200405120","volume":"168","author":"B Stramer","year":"2005","unstructured":"Stramer B, Wood W, Galko MJ, Redd MJ, Jacinto A, Parkhurst SM, Martin P (2005) Live imaging of wound inflammation in Drosophila embryos reveals key roles for small GTPases during in vivo cell migration. J Cell Biol 168:567\u2013573","journal-title":"J Cell Biol"},{"key":"33_CR129","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1083\/jcb.201601091","volume":"212","author":"T Sturner","year":"2016","unstructured":"Sturner T, Tavosanis G (2016) Rotating for elongation: Fat2 whips for the race. J Cell Biol 212:487\u2013489","journal-title":"J Cell Biol"},{"key":"33_CR130","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1016\/S1534-5807(02)00324-6","volume":"3","author":"S Suetsugu","year":"2002","unstructured":"Suetsugu S, Hattori M, Miki H, Tezuka T, Yamamoto T, Mikoshiba K, Takenawa T (2002) Sustained activation of N-WASP through phosphorylation is essential for neurite extension. Dev Cell 3:645\u2013658","journal-title":"Dev Cell"},{"key":"33_CR131","doi-asserted-by":"publisher","first-page":"1397","DOI":"10.1038\/nprot.2009.130","volume":"4","author":"W Supatto","year":"2009","unstructured":"Supatto W, McMahon A, Fraser SE, Stathopoulos A (2009) Quantitative imaging of collective cell migration during Drosophila gastrulation: multiphoton microscopy and computational analysis. Nat Protoc 4:1397\u20131412","journal-title":"Nat Protoc"},{"key":"33_CR132","doi-asserted-by":"crossref","unstructured":"Takenawa T (2005) From N-WASP to WAVE: key molecules for regulation of cortical actin organization. Novartis Found Symp 269:3\u201310; discussion 10\u201315, 30\u201314 passim","DOI":"10.1002\/047001766X.ch2"},{"key":"33_CR133","doi-asserted-by":"publisher","first-page":"260","DOI":"10.1006\/dbio.2002.0571","volume":"243","author":"T Tal","year":"2002","unstructured":"Tal T, Vaizel-Ohayon D, Schejter ED (2002) Conserved interactions with cytoskeletal but not signaling elements are an essential aspect of Drosophila WASp function. Dev Biol 243:260\u2013271","journal-title":"Dev Biol"},{"key":"33_CR134","doi-asserted-by":"publisher","first-page":"107","DOI":"10.1016\/j.cub.2012.11.059","volume":"23","author":"H Tang","year":"2013","unstructured":"Tang H, Li A, Bi J, Veltman DM, Zech T, Spence HJ, Yu X, Timpson P, Insall RH, Frame MC, Machesky LM (2013) Loss of Scar\/WAVE complex promotes N-WASP- and FAK-dependent invasion. Curr Biol 23:107\u2013117","journal-title":"Curr Biol"},{"key":"33_CR135","doi-asserted-by":"publisher","first-page":"1973","DOI":"10.1073\/pnas.1119578109","volume":"109","author":"K Tanner","year":"2012","unstructured":"Tanner K, Mori H, Mroue R, Bruni-Cardoso A, Bissell MJ (2012) Coherent angular motion in the establishment of multicellular architecture of glandular tissues. Proc Natl Acad Sci U S A 109:1973\u20131978","journal-title":"Proc Natl Acad Sci U S A"},{"key":"33_CR136","doi-asserted-by":"crossref","unstructured":"Taylor MD, Sadhukhan S, Kottangada P, Ramgopal A, Sarkar K, D\u2019Silva S, Selvakumar A, Candotti F, Vyas YM (2010) Nuclear role of WASp in the pathogenesis of dysregulated TH1 immunity in human Wiskott-Aldrich syndrome. Sci Transl Med 2:37ra44","DOI":"10.1126\/scitranslmed.3000813"},{"key":"33_CR137","doi-asserted-by":"publisher","first-page":"182","DOI":"10.1038\/nri2724","volume":"10","author":"AJ Thrasher","year":"2010","unstructured":"Thrasher AJ, Burns SO (2010) WASP: a key immunological multitasker. Nat Rev Immunol 10:182\u2013192","journal-title":"Nat Rev Immunol"},{"key":"33_CR138","doi-asserted-by":"publisher","first-page":"2987","DOI":"10.4049\/jimmunol.178.5.2987","volume":"178","author":"S Tsuboi","year":"2007","unstructured":"Tsuboi S (2007) Requirement for a complex of Wiskott-Aldrich syndrome protein (WASP) with WASP interacting protein in podosome formation in macrophages. J Immunol 178:2987\u20132995","journal-title":"J Immunol"},{"key":"33_CR139","doi-asserted-by":"publisher","first-page":"2880","DOI":"10.1091\/mbc.E10-04-0372","volume":"21","author":"DM Veltman","year":"2010","unstructured":"Veltman DM, Insall RH (2010) WASP family proteins: their evolution and its physiological implications. Mol Biol Cell 21:2880\u20132893","journal-title":"Mol Biol Cell"},{"key":"33_CR140","doi-asserted-by":"publisher","first-page":"671","DOI":"10.1016\/j.tcb.2012.08.012","volume":"22","author":"T Vignaud","year":"2012","unstructured":"Vignaud T, Blanchoin L, Thery M (2012) Directed cytoskeleton self-organization. Trends Cell Biol 22:671\u2013682","journal-title":"Trends Cell Biol"},{"key":"33_CR141","doi-asserted-by":"publisher","first-page":"414","DOI":"10.1038\/ng0495-414","volume":"9","author":"A Villa","year":"1995","unstructured":"Villa A, Notarangelo L, Macchi P, Mantuano E, Cavagni G, Brugnoni D, Strina D, Patrosso MC, Ramenghi U, Sacco MG et al (1995) X-linked thrombocytopenia and Wiskott-Aldrich syndrome are allelic diseases with mutations in the WASP gene. Nat Genet 9:414\u2013417","journal-title":"Nat Genet"},{"key":"33_CR142","doi-asserted-by":"publisher","first-page":"483","DOI":"10.1016\/j.devcel.2006.02.003","volume":"10","author":"XJ Wang","year":"2006","unstructured":"Wang XJ, Bo JY, Bridges T, Dugan KD, Pan TC, Chodosh LA, Montell DJ (2006) Analysis of cell migration using whole-genome expression profiling of migratory cells in the Drosophila ovary. Dev Cell 10:483\u2013495","journal-title":"Dev Cell"},{"key":"33_CR143","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1038\/ncb2061","volume":"12","author":"X Wang","year":"2010","unstructured":"Wang X, He L, Wu YI, Hahn KM, Montell DJ (2010) Light-mediated activation reveals a key role for Rac in collective guidance of cell movement in vivo. Nat Cell Biol 12:591\u2013597","journal-title":"Nat Cell Biol"},{"key":"33_CR144","doi-asserted-by":"publisher","first-page":"163","DOI":"10.1073\/pnas.1201141110","volume":"110","author":"H Wang","year":"2013","unstructured":"Wang H, Lacoche S, Huang L, Xue B, Muthuswamy SK (2013) Rotational motion during three-dimensional morphogenesis of mammary epithelial acini relates to laminin matrix assembly. Proc Natl Acad Sci U S A 110:163\u2013168","journal-title":"Proc Natl Acad Sci U S A"},{"key":"33_CR145","doi-asserted-by":"publisher","first-page":"639","DOI":"10.1534\/genetics.114.171785","volume":"199","author":"MF Wangler","year":"2015","unstructured":"Wangler MF, Yamamoto S, Bellen HJ (2015) Fruit flies in biomedical research. Genetics 199:639\u2013653","journal-title":"Genetics"},{"key":"33_CR146","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1186\/s13104-015-0981-7","volume":"8","author":"C Weiss","year":"2015","unstructured":"Weiss C, Schultz J (2015) Identification of divergent WH2 motifs by HMM-HMM alignments. BMC Res Notes 8:18","journal-title":"BMC Res Notes"},{"key":"33_CR147","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1083\/jcb.200508161","volume":"173","author":"W Wood","year":"2006","unstructured":"Wood W, Faria C, Jacinto A (2006) Distinct mechanisms regulate hemocyte chemotaxis during development and wound healing in Drosophila melanogaster. J Cell Biol 173:405\u2013416","journal-title":"J Cell Biol"},{"key":"33_CR148","doi-asserted-by":"publisher","first-page":"2685","DOI":"10.1038\/emboj.2013.189","volume":"32","author":"P Xia","year":"2013","unstructured":"Xia P, Wang S, Du Y, Zhao Z, Shi L, Sun L, Huang G, Ye B, Li C, Dai Z, Hou N, Cheng X, Sun Q, Li L, Yang X, Fan Z (2013) WASH inhibits autophagy through suppression of Beclin 1 ubiquitination. EMBO J 32:2685\u20132696","journal-title":"EMBO J"},{"key":"33_CR149","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1004447","volume":"10","author":"X Xiao","year":"2014","unstructured":"Xiao X, Mruk DD, Tang EI, Massarwa R, Mok KW, Li N, Wong CK, Lee WM, Snapper SB, Shilo BZ, Schejter ED, Cheng CY (2014) N-wasp is required for structural integrity of the blood-testis barrier. PLoS Genet 10, e1004447","journal-title":"PLoS Genet"},{"key":"33_CR150","doi-asserted-by":"publisher","first-page":"3602","DOI":"10.1093\/emboj\/cdg350","volume":"22","author":"C Yan","year":"2003","unstructured":"Yan C, Martinez-Quiles N, Eden S, Shibata T, Takeshima F, Shinkura R, Fujiwara Y, Bronson R, Snapper SB, Kirschner MW, Geha R, Rosen FS, Alt FW (2003) WAVE2 deficiency reveals distinct roles in embryogenesis and Rac-mediated actin-based motility. EMBO J 22:3602\u20133612","journal-title":"EMBO J"},{"key":"33_CR151","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1083\/jcb.201203154","volume":"199","author":"SK Yoo","year":"2012","unstructured":"Yoo SK, Freisinger CM, LeBert DC, Huttenlocher A (2012) Early redox, Src family kinase, and calcium signaling integrate wound responses and tissue regeneration in zebrafish. J Cell Biol 199:225\u2013234","journal-title":"J Cell Biol"},{"key":"33_CR152","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1083\/jcb.201203025","volume":"199","author":"X Yu","year":"2012","unstructured":"Yu X, Zech T, McDonald L, Gonzalez EG, Li A, Macpherson I, Schwarz JP, Spence H, Futo K, Timpson P, Nixon C, Ma Y, Anton IM, Visegrady B, Insall RH, Oien K, Blyth K, Norman JC, Machesky LM (2012) N-WASP coordinates the delivery and F-actin-mediated capture of MT1-MMP at invasive pseudopods. J Cell Biol 199:527\u2013544","journal-title":"J Cell Biol"},{"key":"33_CR153","doi-asserted-by":"publisher","first-page":"689","DOI":"10.1083\/jcb.200109057","volume":"156","author":"JA Zallen","year":"2002","unstructured":"Zallen JA, Cohen Y, Hudson AM, Cooley L, Wieschaus E, Schejter ED (2002) SCAR is a primary regulator of Arp2\/3-dependent morphological events in Drosophila. J Cell Biol 156:689\u2013701","journal-title":"J Cell Biol"},{"key":"33_CR154","doi-asserted-by":"publisher","first-page":"224","DOI":"10.1111\/jmi.12020","volume":"251","author":"T Zobel","year":"2013","unstructured":"Zobel T, Bogdan S (2013) A high resolution view of the fly actin cytoskeleton lacking a functional WAVE complex. J Microsc 251:224\u2013231","journal-title":"J Microsc"},{"key":"33_CR156","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1038\/ncb1852","volume":"11","author":"JB Zuchero","year":"2009","unstructured":"Zuchero JB, Coutts AS, Quinlan ME, La Thangue NB, Mullins RD (2009) p53-cofactor JMY is a multifunctional actin nucleation factor. Nat Cell Biol 11:451\u2013459","journal-title":"Nat Cell Biol"}],"container-title":["Handbook of Experimental Pharmacology","The Actin Cytoskeleton"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/164_2016_33","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,20]],"date-time":"2023-08-20T13:54:07Z","timestamp":1692539647000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/164_2016_33"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"ISBN":["9783319463698","9783319463711"],"references-count":160,"URL":"https:\/\/doi.org\/10.1007\/164_2016_33","relation":{},"ISSN":["0171-2004","1865-0325"],"issn-type":[{"value":"0171-2004","type":"print"},{"value":"1865-0325","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016]]},"assertion":[{"value":"19 October 2016","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}}]}}