{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,27]],"date-time":"2025-03-27T04:22:10Z","timestamp":1743049330618,"version":"3.40.3"},"publisher-location":"Cham","reference-count":58,"publisher":"Springer International Publishing","isbn-type":[{"type":"print","value":"9783030840471"},{"type":"electronic","value":"9783030840488"}],"license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.springer.com\/tdm"}],"content-domain":{"domain":["link.springer.com"],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021]]},"DOI":"10.1007\/164_2021_489","type":"book-chapter","created":{"date-parts":[[2021,11,21]],"date-time":"2021-11-21T21:05:48Z","timestamp":1637528748000},"page":"151-170","update-policy":"https:\/\/doi.org\/10.1007\/springer_crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Precision Medicine in Chronic Rhinosinusitis: Where Does Allergy Fit In?"],"prefix":"10.1007","author":[{"given":"Xinni","family":"Xu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yew Kwang","family":"Ong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"De Yun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2021,6,4]]},"reference":[{"issue":"5","key":"489_CR1","first-page":"420","volume":"86","author":"S Aeumjaturapat","year":"2003","unstructured":"Aeumjaturapat S, Saengpanich S, Isipradit P, Keelawat S (2003) Eosinophilic mucin rhinosinusitis: terminology and clinicopathological presentation. J Med Assoc Thai 86(5):420\u2013424","journal-title":"J Med Assoc Thai"},{"issue":"6","key":"489_CR2","doi-asserted-by":"publisher","first-page":"421","DOI":"10.2500\/ajra.2015.29.4244","volume":"29","author":"A Amali","year":"2015","unstructured":"Amali A, Saedi B, Rahavi-Ezabadi S, Ghazavi H, Hassanpoor N (2015) Long-term postoperative azithromycin in patients with chronic rhinosinusitis: a randomized clinical trial. Am J Rhinol Allergy 29(6):421\u2013424. https:\/\/doi.org\/10.2500\/ajra.2015.29.4244","journal-title":"Am J Rhinol Allergy"},{"issue":"4","key":"489_CR3","doi-asserted-by":"publisher","first-page":"607","DOI":"10.1067\/mai.2001.112374","volume":"107","author":"C Bachert","year":"2001","unstructured":"Bachert C, Gevaert P, Holtappels G, Johansson SG, van Cauwenberge P (2001) Total and specific IgE in nasal polyps is related to local eosinophilic inflammation. J Allergy Clin Immunol 107(4):607\u2013614. https:\/\/doi.org\/10.1067\/mai.2001.112374","journal-title":"J Allergy Clin Immunol"},{"issue":"4","key":"489_CR4","doi-asserted-by":"publisher","first-page":"1024","DOI":"10.1016\/j.jaci.2017.05.044","volume":"140","author":"C Bachert","year":"2017","unstructured":"Bachert C, Sousa AR, Lund VJ, Scadding GK, Gevaert P, Nasser S, Durham SR, Cornet ME, Kariyawasam HH, Gilbert J, Austin D, Maxwell AC, Marshall RP, Fokkens WJ (2017) Reduced need for surgery in severe nasal polyposis with mepolizumab: randomized trial. J Allergy Clin Immunol 140(4):1024\u20131031.e1014. https:\/\/doi.org\/10.1016\/j.jaci.2017.05.044","journal-title":"J Allergy Clin Immunol"},{"key":"489_CR5","doi-asserted-by":"crossref","unstructured":"Bachert C, Desrosiers M, Mullol J, Hellings P, Cervin A, Sher L, Bosso J, Lee S, Maspero J, Fujieda S (2019) A randomized phase 3 study, Sinus-52, evaluating the efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps. J Allergy Clin Immunol 143(2)","DOI":"10.1016\/j.jaci.2018.12.980"},{"issue":"10","key":"489_CR6","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1007\/s004050000271","volume":"257","author":"G Bachmann","year":"2000","unstructured":"Bachmann G, Hommel G, Michel O (2000) Effect of irrigation of the nose with isotonic salt solution on adult patients with chronic paranasal sinus disease. Eur Arch Otorhinolaryngol 257(10):537\u2013541","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"5","key":"489_CR7","doi-asserted-by":"publisher","first-page":"1126","DOI":"10.1016\/j.jaci.2008.02.010","volume":"121","author":"FM Baroody","year":"2008","unstructured":"Baroody FM, Mucha SM, Detineo M, Naclerio RM (2008) Nasal challenge with allergen leads to maxillary sinus inflammation. J Allergy Clin Immunol 121(5):1126\u20131132.e1127. https:\/\/doi.org\/10.1016\/j.jaci.2008.02.010","journal-title":"J Allergy Clin Immunol"},{"issue":"5","key":"489_CR8","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1177\/019459989411100508","volume":"111","author":"JP Bent 3rd","year":"1994","unstructured":"Bent JP 3rd, Kuhn FA (1994) Diagnosis of allergic fungal sinusitis. Otolaryngol Head Neck Surg 111(5):580\u2013588. https:\/\/doi.org\/10.1177\/019459989411100508","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"2","key":"489_CR9","doi-asserted-by":"publisher","first-page":"264","DOI":"10.1097\/00005537-200302000-00013","volume":"113","author":"H Braun","year":"2003","unstructured":"Braun H, Buzina W, Freudenschuss K, Beham A, Stammberger H (2003) \u2018Eosinophilic fungal rhinosinusitis\u2019: a common disorder in Europe? Laryngoscope 113(2):264\u2013269. https:\/\/doi.org\/10.1097\/00005537-200302000-00013","journal-title":"Laryngoscope"},{"issue":"10","key":"489_CR10","doi-asserted-by":"publisher","first-page":"1541","DOI":"10.1016\/j.ijporl.2008.07.008","volume":"72","author":"SE Brietzke","year":"2008","unstructured":"Brietzke SE, Brigger MT (2008) Adenoidectomy outcomes in pediatric rhinosinusitis: a meta-analysis. Int J Pediatr Otorhinolaryngol 72(10):1541\u20131545. https:\/\/doi.org\/10.1016\/j.ijporl.2008.07.008","journal-title":"Int J Pediatr Otorhinolaryngol"},{"issue":"4","key":"489_CR11","doi-asserted-by":"publisher","first-page":"542","DOI":"10.1177\/0194599814549302","volume":"151","author":"SE Brietzke","year":"2014","unstructured":"Brietzke SE, Shin JJ, Choi S, Lee JT, Parikh SR, Pena M, Prager JD, Ramadan H, Veling M, Corrigan M, Rosenfeld RM (2014) Clinical consensus statement: pediatric chronic rhinosinusitis. Otolaryngol Head Neck Surg 151(4):542\u2013553. https:\/\/doi.org\/10.1177\/0194599814549302","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"3","key":"489_CR12","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1177\/0194599817711887","volume":"157","author":"JP Brunner","year":"2017","unstructured":"Brunner JP, Jawad BA, McCoul ED (2017) Polypoid change of the middle turbinate and paranasal sinus polyposis are distinct entities. Otolaryngol Head Neck Surg 157(3):519\u2013523. https:\/\/doi.org\/10.1177\/0194599817711887","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"1","key":"489_CR13","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/j.anai.2018.10.014","volume":"122","author":"PP Cao","year":"2019","unstructured":"Cao PP, Wang ZC, Schleimer RP, Liu Z (2019) Pathophysiologic mechanisms of chronic rhinosinusitis and their roles in emerging disease endotypes. Ann Allergy Asthma Immunol 122(1):33\u201340. https:\/\/doi.org\/10.1016\/j.anai.2018.10.014","journal-title":"Ann Allergy Asthma Immunol"},{"issue":"5","key":"489_CR14","doi-asserted-by":"publisher","first-page":"294","DOI":"10.1111\/myc.12314","volume":"58","author":"A Chakrabarti","year":"2015","unstructured":"Chakrabarti A, Rudramurthy SM, Panda N, Das A, Singh A (2015) Epidemiology of chronic fungal rhinosinusitis in rural India. Mycoses 58(5):294\u2013302. https:\/\/doi.org\/10.1111\/myc.12314","journal-title":"Mycoses"},{"issue":"3","key":"489_CR15","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1177\/194589240301700303","volume":"17","author":"MM Collins","year":"2003","unstructured":"Collins MM, Nair SB, Wormald PJ (2003) Prevalence of noninvasive fungal sinusitis in South Australia. Am J Rhinol 17(3):127\u2013132","journal-title":"Am J Rhinol"},{"issue":"4","key":"489_CR16","doi-asserted-by":"publisher","first-page":"228","DOI":"10.2500\/ajra.2017.31.4443","volume":"31","author":"JM DelGaudio","year":"2017","unstructured":"DelGaudio JM, Loftus PA, Hamizan AW, Harvey RJ, Wise SK (2017) Central compartment atopic disease. Am J Rhinol Allergy 31(4):228\u2013234. https:\/\/doi.org\/10.2500\/ajra.2017.31.4443","journal-title":"Am J Rhinol Allergy"},{"issue":"2","key":"489_CR17","doi-asserted-by":"publisher","first-page":"145","DOI":"10.2500\/ajra.2014.28.4019","volume":"28","author":"K DeYoung","year":"2014","unstructured":"DeYoung K, Wentzel JL, Schlosser RJ, Nguyen SA, Soler ZM (2014) Systematic review of immunotherapy for chronic rhinosinusitis. Am J Rhinol Allergy 28(2):145\u2013150. https:\/\/doi.org\/10.2500\/ajra.2014.28.4019","journal-title":"Am J Rhinol Allergy"},{"issue":"4","key":"489_CR18","doi-asserted-by":"publisher","first-page":"483","DOI":"10.2500\/ajr.2007.21.3047","volume":"21","author":"MG Dubin","year":"2007","unstructured":"Dubin MG, Liu C, Lin SY, Senior BA (2007) American Rhinologic Society member survey on \u201cmaximal medical therapy\u201d for chronic rhinosinusitis. Am J Rhinol 21(4):483\u2013488","journal-title":"Am J Rhinol"},{"issue":"5","key":"489_CR19","doi-asserted-by":"publisher","first-page":"e146","DOI":"10.2500\/ajra.2013.27.3950","volume":"27","author":"M Fandino","year":"2013","unstructured":"Fandino M, Macdonald KI, Lee J, Witterick IJ (2013) The use of postoperative topical corticosteroids in chronic rhinosinusitis with nasal polyps: a systematic review and meta-analysis. Am J Rhinol Allergy 27(5):e146\u2013e157. https:\/\/doi.org\/10.2500\/ajra.2013.27.3950","journal-title":"Am J Rhinol Allergy"},{"issue":"5 Pt 1","key":"489_CR20","doi-asserted-by":"publisher","first-page":"799","DOI":"10.1097\/00005537-200005000-00010","volume":"110","author":"BJ Ferguson","year":"2000","unstructured":"Ferguson BJ (2000) Eosinophilic mucin rhinosinusitis: a distinct clinicopathological entity. Laryngoscope 110(5 Pt 1):799\u2013813. https:\/\/doi.org\/10.1097\/00005537-200005000-00010","journal-title":"Laryngoscope"},{"issue":"2","key":"489_CR21","doi-asserted-by":"publisher","first-page":"441","DOI":"10.1016\/S0030-6665(00)80018-3","volume":"33","author":"BJ Ferguson","year":"2000","unstructured":"Ferguson BJ, Barnes L, Bernstein JM, Brown D, Clark CE 3rd, Cook PR, DeWitt WS, Graham SM, Gordon B, Javer AR, Krouse JH, Kuhn FA, Levine HL, Manning SC, Marple BF, Morgan AH, Osguthorpe JD, Skedros D, Rains BM 3rd, Ramadan HH, Terrell JE, Yonkers AJ (2000) Geographic variation in allergic fungal rhinosinusitis. Otolaryngol Clin North Am 33(2):441\u2013449","journal-title":"Otolaryngol Clin North Am"},{"key":"489_CR22","doi-asserted-by":"publisher","unstructured":"Fokkens WJ, Reitsma S (2019) Proposal for an algorithm on the management of chronic rhinosinusitis. Allergy. https:\/\/doi.org\/10.1111\/all.13797","DOI":"10.1111\/all.13797"},{"issue":"Suppl S29","key":"489_CR23","first-page":"1","volume":"58","author":"WJ Fokkens","year":"2020","unstructured":"Fokkens WJ, Lund VJ, Hopkins C, Hellings PW, Kern R, Reitsma S, Toppila-Salmi S, Bernal-Sprekelsen M (2020) European position paper on rhinosinusitis and nasal polyps 2020. Rhinology 58(Suppl S29):1\u2013464","journal-title":"Rhinology"},{"issue":"9","key":"489_CR24","doi-asserted-by":"publisher","first-page":"702","DOI":"10.1002\/alr.21352","volume":"4","author":"EC Gan","year":"2014","unstructured":"Gan EC, Thamboo A, Rudmik L, Hwang PH, Ferguson BJ, Javer AR (2014) Medical management of allergic fungal rhinosinusitis following endoscopic sinus surgery: an evidence-based review and recommendations. Int Forum Allergy Rhinol 4(9):702\u2013715. https:\/\/doi.org\/10.1002\/alr.21352","journal-title":"Int Forum Allergy Rhinol"},{"issue":"5","key":"489_CR25","doi-asserted-by":"publisher","first-page":"989","DOI":"10.1016\/j.jaci.2011.07.056","volume":"128","author":"P Gevaert","year":"2011","unstructured":"Gevaert P, Van Bruaene N, Cattaert T, Van Steen K, Van Zele T, Acke F, De Ruyck N, Blomme K, Sousa AR, Marshall RP, Bachert C (2011) Mepolizumab, a humanized anti-IL-5 mAb, as a treatment option for severe nasal polyposis. J Allergy Clin Immunol 128(5):989\u2013995.e981\u2013988. https:\/\/doi.org\/10.1016\/j.jaci.2011.07.056","journal-title":"J Allergy Clin Immunol"},{"issue":"3","key":"489_CR26","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1016\/j.jaci.2020.05.032","volume":"146","author":"P Gevaert","year":"2020","unstructured":"Gevaert P, Omachi TA, Corren J, Mullol J, Han J, Lee SE, Kaufman D, Ligueros-Saylan M, Howard M (2020) Efficacy and safety of omalizumab in nasal polyposis: 2 randomized phase 3 trials. J Allergy Clin Immunol 146(3):595\u2013605","journal-title":"J Allergy Clin Immunol"},{"issue":"1","key":"489_CR27","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/j.otohns.2005.03.028","volume":"133","author":"BS Goh","year":"2005","unstructured":"Goh BS, Gendeh BS, Rose IM, Pit S, Samad SA (2005) Prevalence of allergic fungal sinusitis in refractory chronic rhinosinusitis in adult Malaysians. Otolaryngol Head Neck Surg 133(1):27\u201331. https:\/\/doi.org\/10.1016\/j.otohns.2005.03.028","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"S1","key":"489_CR28","doi-asserted-by":"publisher","first-page":"S9","DOI":"10.1002\/alr.22331","volume":"9","author":"JW Grayson","year":"2019","unstructured":"Grayson JW, Harvey RJ (2019) Topical corticosteroid irrigations in chronic rhinosinusitis. Int Forum Allergy Rhinol 9(S1):S9\u2013S15. https:\/\/doi.org\/10.1002\/alr.22331","journal-title":"Int Forum Allergy Rhinol"},{"issue":"1","key":"489_CR29","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1002\/alr.21835","volume":"7","author":"AW Hamizan","year":"2017","unstructured":"Hamizan AW, Christensen JM, Ebenzer J, Oakley G, Tattersall J, Sacks R, Harvey RJ (2017) Middle turbinate edema as a diagnostic marker of inhalant allergy. Int Forum Allergy Rhinol 7(1):37\u201342. https:\/\/doi.org\/10.1002\/alr.21835","journal-title":"Int Forum Allergy Rhinol"},{"issue":"2","key":"489_CR30","doi-asserted-by":"publisher","first-page":"AB422","DOI":"10.1016\/j.jaci.2018.12.948","volume":"143","author":"JK Han","year":"2019","unstructured":"Han JK, Bachert C, Desrosiers M, Laidlaw TM, Hopkins C, Fokkens WJ, Paggiaro P, Cho SH (2019) Efficacy and safety of Dupilumab in patients with chronic rhinosinusitis with nasal polyps: results from the randomized phase 3 Sinus-24 study. J Allergy Clin Immunol 143(2):AB422","journal-title":"J Allergy Clin Immunol"},{"issue":"5","key":"489_CR31","doi-asserted-by":"publisher","first-page":"1048","DOI":"10.1002\/lary.25052","volume":"125","author":"BR Haxel","year":"2015","unstructured":"Haxel BR, Clemens M, Karaiskaki N, Dippold U, Kettern L, Mann WJ (2015) Controlled trial for long-term low-dose erythromycin after sinus surgery for chronic rhinosinusitis. Laryngoscope 125(5):1048\u20131055. https:\/\/doi.org\/10.1002\/lary.25052","journal-title":"Laryngoscope"},{"key":"489_CR32","doi-asserted-by":"publisher","first-page":"CD012453","DOI":"10.1002\/14651858.CD012453.pub2","volume":"9","author":"K Head","year":"2018","unstructured":"Head K, Sharp S, Chong LY, Hopkins C, Philpott C (2018) Topical and systemic antifungal therapy for chronic rhinosinusitis. Cochrane Database Syst Rev 9:CD012453. https:\/\/doi.org\/10.1002\/14651858.CD012453.pub2","journal-title":"Cochrane Database Syst Rev"},{"issue":"1","key":"489_CR33","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1016\/j.jaci.2006.03.012","volume":"118","author":"P Hissaria","year":"2006","unstructured":"Hissaria P, Smith W, Wormald PJ, Taylor J, Vadas M, Gillis D, Kette F (2006) Short course of systemic corticosteroids in sinonasal polyposis: a double-blind, randomized, placebo-controlled trial with evaluation of outcome measures. J Allergy Clin Immunol 118(1):128\u2013133. https:\/\/doi.org\/10.1016\/j.jaci.2006.03.012","journal-title":"J Allergy Clin Immunol"},{"issue":"6","key":"489_CR34","doi-asserted-by":"publisher","first-page":"624","DOI":"10.1165\/ajrcmb.12.6.7539273","volume":"12","author":"FL Jahnsen","year":"1995","unstructured":"Jahnsen FL, Haraldsen G, Aanesen JP, Haye R, Brandtzaeg P (1995) Eosinophil infiltration is related to increased expression of vascular cell adhesion molecule-1 in nasal polyps. Am J Respir Cell Mol Biol 12(6):624\u2013632. https:\/\/doi.org\/10.1165\/ajrcmb.12.6.7539273","journal-title":"Am J Respir Cell Mol Biol"},{"issue":"1","key":"489_CR35","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/j.otohns.2008.03.009","volume":"139","author":"SJ Kanowitz","year":"2008","unstructured":"Kanowitz SJ, Batra PS, Citardi MJ (2008) Topical budesonide via mucosal atomization device in refractory postoperative chronic rhinosinusitis. Otolaryngol Head Neck Surg 139(1):131\u2013136. https:\/\/doi.org\/10.1016\/j.otohns.2008.03.009","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"12","key":"489_CR36","doi-asserted-by":"publisher","first-page":"2950","DOI":"10.1002\/lary.24239","volume":"123","author":"K Lam","year":"2013","unstructured":"Lam K, Tan BK, Lavin JM, Meen E, Conley DB (2013) Comparison of nasal sprays and irrigations in the delivery of topical agents to the olfactory mucosa. Laryngoscope 123(12):2950\u20132957. https:\/\/doi.org\/10.1002\/lary.24239","journal-title":"Laryngoscope"},{"issue":"3","key":"489_CR37","doi-asserted-by":"publisher","first-page":"637","DOI":"10.1111\/coa.12787","volume":"42","author":"A Lasso","year":"2017","unstructured":"Lasso A, Masoudian P, Quinn JG, Cowan J, Labajian V, Bonaparte JP, Kilty S (2017) Long-term low-dose macrolides for chronic rhinosinusitis in adults \u2013 a systematic review of the literature. Clin Otolaryngol 42(3):637\u2013650. https:\/\/doi.org\/10.1111\/coa.12787","journal-title":"Clin Otolaryngol"},{"issue":"6","key":"489_CR38","doi-asserted-by":"publisher","first-page":"121","DOI":"10.3810\/pgm.2009.11.2081","volume":"121","author":"BF Marple","year":"2009","unstructured":"Marple BF, Stankiewicz JA, Baroody FM, Chow JM, Conley DB, Corey JP, Ferguson BJ, Kern RC, Lusk RP, Naclerio RM, Orlandi RR, Parker MJ, American Academy of Otolaryngic Allergy Working Group on Chronic R (2009) Diagnosis and management of chronic rhinosinusitis in adults. Postgrad Med 121(6):121\u2013139. https:\/\/doi.org\/10.3810\/pgm.2009.11.2081","journal-title":"Postgrad Med"},{"issue":"Suppl 1","key":"489_CR39","doi-asserted-by":"publisher","first-page":"S22","DOI":"10.1002\/alr.21695","volume":"6","author":"RR Orlandi","year":"2016","unstructured":"Orlandi RR, Kingdom TT, Hwang PH, Smith TL, Alt JA, Baroody FM, Batra PS, Bernal-Sprekelsen M, Bhattacharyya N, Chandra RK, Chiu A, Citardi MJ, Cohen NA, DelGaudio J, Desrosiers M, Dhong HJ, Douglas R, Ferguson B, Fokkens WJ, Georgalas C, Goldberg A, Gosepath J, Hamilos DL, Han JK, Harvey R, Hellings P, Hopkins C, Jankowski R, Javer AR, Kern R, Kountakis S, Kowalski ML, Lane A, Lanza DC, Lebowitz R, Lee HM, Lin SY, Lund V, Luong A, Mann W, Marple BF, McMains KC, Metson R, Naclerio R, Nayak JV, Otori N, Palmer JN, Parikh SR, Passali D, Peters A, Piccirillo J, Poetker DM, Psaltis AJ, Ramadan HH, Ramakrishnan VR, Riechelmann H, Roh HJ, Rudmik L, Sacks R, Schlosser RJ, Senior BA, Sindwani R, Stankiewicz JA, Stewart M, Tan BK, Toskala E, Voegels R, Wang DY, Weitzel EK, Wise S, Woodworth BA, Wormald PJ, Wright ED, Zhou B, Kennedy DW (2016) International consensus statement on allergy and rhinology: rhinosinusitis. Int Forum Allergy Rhinol 6(Suppl 1):S22\u2013S209. https:\/\/doi.org\/10.1002\/alr.21695","journal-title":"Int Forum Allergy Rhinol"},{"issue":"4","key":"489_CR40","doi-asserted-by":"publisher","first-page":"601","DOI":"10.1097\/01.mlg.0000161341.00258.54","volume":"115","author":"H Pant","year":"2005","unstructured":"Pant H, Kette FE, Smith WB, Wormald PJ, Macardle PJ (2005) Fungal-specific humoral response in eosinophilic mucus chronic rhinosinusitis. Laryngoscope 115(4):601\u2013606. https:\/\/doi.org\/10.1097\/01.mlg.0000161341.00258.54","journal-title":"Laryngoscope"},{"issue":"3","key":"489_CR41","doi-asserted-by":"publisher","first-page":"201","DOI":"10.2500\/ajra.2012.26.3747","volume":"26","author":"AJ Psaltis","year":"2012","unstructured":"Psaltis AJ, Foreman A, Wormald PJ, Schlosser RJ (2012) Contamination of sinus irrigation devices: a review of the evidence and clinical relevance. Am J Rhinol Allergy 26(3):201\u2013203. https:\/\/doi.org\/10.2500\/ajra.2012.26.3747","journal-title":"Am J Rhinol Allergy"},{"issue":"1","key":"489_CR42","doi-asserted-by":"publisher","first-page":"3","DOI":"10.4193\/Rhin15.079","volume":"54","author":"V Pundir","year":"2016","unstructured":"Pundir V, Pundir J, Lancaster G, Baer S, Kirkland P, Cornet M, Lourijsen ES, Georgalas C, Fokkens WJ (2016) Role of corticosteroids in functional endoscopic sinus surgery \u2013 a systematic review and meta-analysis. Rhinology 54(1):3\u201319. https:\/\/doi.org\/10.4193\/Rhin15.079","journal-title":"Rhinology"},{"issue":"3","key":"489_CR43","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1177\/0194599812470427","volume":"148","author":"MA Pynnonen","year":"2013","unstructured":"Pynnonen MA, Venkatraman G, Davis GE (2013) Macrolide therapy for chronic rhinosinusitis: a meta-analysis. Otolaryngol Head Neck Surg 148(3):366\u2013373. https:\/\/doi.org\/10.1177\/0194599812470427","journal-title":"Otolaryngol Head Neck Surg"},{"issue":"4","key":"489_CR44","doi-asserted-by":"publisher","first-page":"MC01","DOI":"10.7860\/JCDR\/2017\/23488.9610","volume":"11","author":"M Rojita","year":"2017","unstructured":"Rojita M, Samal S, Pradhan P, Venkatachalam VP (2017) Comparison of steroid and Itraconazole for prevention of recurrence in allergic fungal rhinosinusitis: a randomized controlled trial. J Clin Diagn Res 11(4):MC01\u2013MC03. https:\/\/doi.org\/10.7860\/JCDR\/2017\/23488.9610","journal-title":"J Clin Diagn Res"},{"issue":"2","key":"489_CR45","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1007\/s00405-009-1075-8","volume":"267","author":"V Rupa","year":"2010","unstructured":"Rupa V, Jacob M, Mathews MS, Seshadri MS (2010) A prospective, randomised, placebo-controlled trial of postoperative oral steroid in allergic fungal sinusitis. Eur Arch Otorhinolaryngol 267(2):233\u2013238. https:\/\/doi.org\/10.1007\/s00405-009-1075-8","journal-title":"Eur Arch Otorhinolaryngol"},{"issue":"1","key":"489_CR46","first-page":"1","volume":"22","author":"J Sastre","year":"2012","unstructured":"Sastre J, Mosges R (2012) Local and systemic safety of intranasal corticosteroids. J Investig Allergol Clin Immunol 22(1):1\u201312","journal-title":"J Investig Allergol Clin Immunol"},{"issue":"5","key":"489_CR47","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1002\/alr.21047","volume":"2","author":"K Snidvongs","year":"2012","unstructured":"Snidvongs K, Pratt E, Chin D, Sacks R, Earls P, Harvey RJ (2012) Corticosteroid nasal irrigations after endoscopic sinus surgery in the management of chronic rhinosinusitis. Int Forum Allergy Rhinol 2(5):415\u2013421. https:\/\/doi.org\/10.1002\/alr.21047","journal-title":"Int Forum Allergy Rhinol"},{"issue":"7","key":"489_CR48","doi-asserted-by":"publisher","first-page":"533","DOI":"10.1002\/alr.21318","volume":"4","author":"A Varvyanskaya","year":"2014","unstructured":"Varvyanskaya A, Lopatin A (2014) Efficacy of long-term low-dose macrolide therapy in preventing early recurrence of nasal polyps after endoscopic sinus surgery. Int Forum Allergy Rhinol 4(7):533\u2013541. https:\/\/doi.org\/10.1002\/alr.21318","journal-title":"Int Forum Allergy Rhinol"},{"issue":"11","key":"489_CR49","doi-asserted-by":"publisher","first-page":"1457","DOI":"10.1111\/j.1398-9995.2011.02693.x","volume":"66","author":"WJ Videler","year":"2011","unstructured":"Videler WJ, Badia L, Harvey RJ, Gane S, Georgalas C, van der Meulen FW, Menger DJ, Lehtonen MT, Toppila-Salmi SK, Vento SI, Hytonen M, Hellings PW, Kalogjera L, Lund VJ, Scadding G, Mullol J, Fokkens WJ (2011) Lack of efficacy of long-term, low-dose azithromycin in chronic rhinosinusitis: a randomized controlled trial. Allergy 66(11):1457\u20131468. https:\/\/doi.org\/10.1111\/j.1398-9995.2011.02693.x","journal-title":"Allergy"},{"issue":"2","key":"489_CR50","doi-asserted-by":"publisher","first-page":"189","DOI":"10.1097\/01.mlg.0000191560.53555.08","volume":"116","author":"B Wallwork","year":"2006","unstructured":"Wallwork B, Coman W, Mackay-Sim A, Greiff L, Cervin A (2006) A double-blind, randomized, placebo-controlled trial of macrolide in the treatment of chronic rhinosinusitis. Laryngoscope 116(2):189\u2013193. https:\/\/doi.org\/10.1097\/01.mlg.0000191560.53555.08","journal-title":"Laryngoscope"},{"issue":"4","key":"489_CR51","doi-asserted-by":"publisher","first-page":"181","DOI":"10.3342\/ceo.2012.5.4.181","volume":"5","author":"DY Wang","year":"2012","unstructured":"Wang DY, Lee HP, Gordon BR (2012) Impacts of fluid dynamics simulation in study of nasal airflow physiology and pathophysiology in realistic human three-dimensional nose models. Clin Exp Otorhinolaryngol 5(4):181\u2013187. https:\/\/doi.org\/10.3342\/ceo.2012.5.4.181","journal-title":"Clin Exp Otorhinolaryngol"},{"issue":"10","key":"489_CR52","doi-asserted-by":"publisher","first-page":"2347","DOI":"10.1002\/lary.24066","volume":"123","author":"CC Wei","year":"2013","unstructured":"Wei CC, Adappa ND, Cohen NA (2013) Use of topical nasal therapies in the management of chronic rhinosinusitis. Laryngoscope 123(10):2347\u20132359. https:\/\/doi.org\/10.1002\/lary.24066","journal-title":"Laryngoscope"},{"issue":"6","key":"489_CR53","doi-asserted-by":"publisher","first-page":"482","DOI":"10.2500\/ajra.2013.27.3976","volume":"27","author":"JL Wentzel","year":"2013","unstructured":"Wentzel JL, Soler ZM, DeYoung K, Nguyen SA, Lohia S, Schlosser RJ (2013) Leukotriene antagonists in nasal polyposis: a meta-analysis and systematic review. Am J Rhinol Allergy 27(6):482\u2013489. https:\/\/doi.org\/10.2500\/ajra.2013.27.3976","journal-title":"Am J Rhinol Allergy"},{"issue":"5","key":"489_CR54","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1002\/alr.21290","volume":"4","author":"LJ White","year":"2014","unstructured":"White LJ, Rotella MR, DelGaudio JM (2014) Polypoid changes of the middle turbinate as an indicator of atopic disease. Int Forum Allergy Rhinol 4(5):376\u2013380. https:\/\/doi.org\/10.1002\/alr.21290","journal-title":"Int Forum Allergy Rhinol"},{"issue":"2","key":"489_CR55","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1002\/alr.21258","volume":"4","author":"KF Wilson","year":"2014","unstructured":"Wilson KF, McMains KC, Orlandi RR (2014) The association between allergy and chronic rhinosinusitis with and without nasal polyps: an evidence-based review with recommendations. Int Forum Allergy Rhinol 4(2):93\u2013103. https:\/\/doi.org\/10.1002\/alr.21258","journal-title":"Int Forum Allergy Rhinol"},{"key":"489_CR56","doi-asserted-by":"publisher","unstructured":"Xu X, Ong YK, Wang Y (2019) Novel findings in immunopathophysiology of chronic rhinosinusitis and their role in a model of precision medicine. Allergy. https:\/\/doi.org\/10.1111\/all.14044","DOI":"10.1111\/all.14044"},{"issue":"6","key":"489_CR57","doi-asserted-by":"publisher","first-page":"e203","DOI":"10.2500\/ajra.2011.25.3728","volume":"25","author":"M Zeng","year":"2011","unstructured":"Zeng M, Long XB, Cui YH, Liu Z (2011) Comparison of efficacy of mometasone furoate versus clarithromycin in the treatment of chronic rhinosinusitis without nasal polyps in Chinese adults. Am J Rhinol Allergy 25(6):e203\u2013e207. https:\/\/doi.org\/10.2500\/ajra.2011.25.3728","journal-title":"Am J Rhinol Allergy"},{"issue":"6","key":"489_CR58","doi-asserted-by":"publisher","first-page":"975","DOI":"10.1111\/all.13074","volume":"72","author":"L Zhao","year":"2017","unstructured":"Zhao L, Li YY, Li CW, Chao SS, Liu J, Nam HN, Dung NTN, Shi L, Wang DY (2017) Increase of poorly proliferated p63(+) \/Ki67(+) basal cells forming multiple layers in the aberrant remodeled epithelium in nasal polyps. Allergy 72(6):975\u2013984. https:\/\/doi.org\/10.1111\/all.13074","journal-title":"Allergy"}],"container-title":["Handbook of Experimental Pharmacology","Allergic Diseases \u2013 From Basic Mechanisms to Comprehensive Management and Prevention"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/link.springer.com\/content\/pdf\/10.1007\/164_2021_489","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,11,21]],"date-time":"2021-11-21T21:07:01Z","timestamp":1637528821000},"score":1,"resource":{"primary":{"URL":"https:\/\/link.springer.com\/10.1007\/164_2021_489"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021]]},"ISBN":["9783030840471","9783030840488"],"references-count":58,"URL":"https:\/\/doi.org\/10.1007\/164_2021_489","relation":{},"ISSN":["0171-2004","1865-0325"],"issn-type":[{"type":"print","value":"0171-2004"},{"type":"electronic","value":"1865-0325"}],"subject":[],"published":{"date-parts":[[2021]]},"assertion":[{"value":"4 June 2021","order":1,"name":"first_online","label":"First Online","group":{"name":"ChapterHistory","label":"Chapter History"}},{"value":"The authors declared that no conflict of interest exists.","order":1,"name":"Ethics","group":{"name":"EthicsHeading","label":"Conflict of Interest"}}]}}