{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,9,4]],"date-time":"2024-09-04T21:48:27Z","timestamp":1725486507475},"publisher-location":"Berlin, Heidelberg","reference-count":27,"publisher":"Springer Berlin Heidelberg","isbn-type":[{"type":"print","value":"9783540006053"},{"type":"electronic","value":"9783540364818"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2003]]},"DOI":"10.1007\/3-540-36481-1_7","type":"book-chapter","created":{"date-parts":[[2007,6,16]],"date-time":"2007-06-16T17:17:47Z","timestamp":1182014267000},"page":"75-87","source":"Crossref","is-referenced-by-count":2,"title":["Multiscale Modeling of Alternative Splicing Regulation"],"prefix":"10.1007","author":[{"given":"Damien","family":"Eveillard","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Delphine","family":"Ropers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hidde","family":"de Jong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christiane","family":"Branlant","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Bockmayr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","published-online":{"date-parts":[[2003,2,28]]},"reference":[{"issue":"3","key":"7_CR1","doi-asserted-by":"publisher","first-page":"303","DOI":"10.1142\/S0218339096000223","volume":"4","author":"O. Bernard","year":"1996","unstructured":"Bernard, O., and Gouz\u00e9 J.-L.: Transient behavior of biological models a a tool of qualitative validation-Application to the Droop model and to a N-P-Z model. J.Biol.Syst, 4(3)(1996)303\u2013314 80","journal-title":"J.Biol.Syst"},{"unstructured":"Bockmayr, A., Courtois, A.: Modeling biological items in hybrid concurrent constraint programming (Abstract). In 2nd Int.Conf.System Biology,ICSB\u201901, Pasadena,CA (2001) 76, 82","key":"7_CR2"},{"key":"7_CR3","series-title":"Lect Notes Comput Sci","volume-title":"Using hybrid concurrent constraint programming to model dynamic biological y tem","author":"A. Bockmayr","year":"2002","unstructured":"Bockmayr, A., Courtoi, A.: Using hybrid concurrent constraint programming to model dynamic biological y tem. In 18th International Conference on Logic Programming,ICLP\u201902, Copenhagen Springer, LNCS 2401 (2002) 76, 82"},{"issue":"14","key":"7_CR4","first-page":"4060","volume":"18","author":"M.A. Caputi","year":"1999","unstructured":"Caputi, M.A., Mayeda, M.A., Krainer, A.R.,and Zahler, A.M.:hnRNP A\/B protein are required for inhibition of HIV-1 pre-mRNA plicing. EMBO 18(14) (1999) 4060\u20137 77","journal-title":"hnRNP A\/B protein are required for inhibition of HIV-1 pre-mRNA plicing"},{"unstructured":"Dautry, F., Weill, D.:Kinetic analy is of mRNA metabolism.In Interdisciplinary School on imaging,modelling and manipulating transcriptional regulatory networks, Ambleteuse (2002) 20\/92 82","key":"7_CR5"},{"issue":"1","key":"7_CR6","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1128\/MCB.19.1.251","volume":"19","author":"F. Gatto-Konczak Del","year":"1999","unstructured":"Del Gatto-Konczak, F., Olive, M., Gesnel, M.C., and Breathnach, R.:hnRNP A1 recruited to an exon in vivo can function as an exon splicing ilencer. Mol. Cell.Biol.19 (1)(1999)251\u201360 77","journal-title":"Mol. Cell.Biol."},{"issue":"22","key":"7_CR7","first-page":"6747","volume":"17","author":"B.R. Graveley","year":"1998","unstructured":"Graveley, B.R., Hertel, K.J., Maniatis, T.:A systematic analy is of the factors that determine the trength of pre-mRNA plicing enhancer. EMBO 17(22) (1998)6747\u20136756","journal-title":"A systematic analy is of the factors that determine the trength of pre-mRNA plicing enhancer"},{"unstructured":"Graveley, B.R.:Sorting out the complexity of SR protein functions.RNA 6 (2000) 1197\u20131211 75","key":"7_CR8"},{"issue":"1","key":"7_CR9","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/S0167-6423(97)00006-3","volume":"30","author":"V. Gupta","year":"1998","unstructured":"Gupta, V., Jagadeesan, R., Saraswat V.:Computing with continuous change. Science of computer programming 30(1\u20132) (1998) 3\u201349 76,81","journal-title":"Science of computer programming"},{"key":"7_CR10","series-title":"Lect Notes Comput Sci","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1007\/3-540-60472-3_12","volume-title":"Hybrid Systems","author":"V. Gupta","year":"1995","unstructured":"Gupta, V., Jagadeesan, R., Saraswat V., Bobrow, D.G.:Programming in hybrid constraint language. In Hybrid Systems II 226\u2013251. Springer, LNCS 999 (1995) 76, 81, 82"},{"key":"7_CR11","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1006\/jtbi.1993.1117","volume":"163","author":"B.J. Hammond","year":"1993","unstructured":"Hammond, B.J.:Quantitative Study of the Control of HIV-1 Gene Expression. J.Theor.Biol.163 (1993)199\u2013221 86","journal-title":"J.Theor.Biol."},{"key":"7_CR12","doi-asserted-by":"publisher","first-page":"C47","DOI":"10.1038\/35011540","volume":"402","author":"L.H. Hartwell","year":"1999","unstructured":"Hartwell, L.H., Hopfield, J.J., Leibler, S., Murray, A.W.:From molecular to modular cell biology.Nature 402 (1999) C47\u2013C52 82","journal-title":"Nature"},{"key":"7_CR13","doi-asserted-by":"crossref","DOI":"10.1007\/978-1-4613-1161-4","volume-title":"The regulation of cellular systems","author":"R. Heinrich","year":"1996","unstructured":"Heinrich, R., Schuster, S.:The regulation of cellular systems. Int\u2019l Thomson Publishing, New York (1996)79"},{"unstructured":"Moore, M.J., Query, C.C., Sharp, P.A.:Splicing of precursors to mRNA by the spliceosome.In The RNA World, Cold Spring Harbor Laboratory Press (1993) 303\u2013357 76","key":"7_CR14"},{"issue":"2","key":"7_CR15","doi-asserted-by":"publisher","first-page":"373","DOI":"10.1006\/viro.1995.0010","volume":"213","author":"M. O\u2019Reilly","year":"1995","unstructured":"O\u2019Reilly, M., McNally, M.T., Beemon, K.L.:Two strong 5\u2019 plice ites and competing, suboptimal 3\u2019splice ites involved in alternative plicing of human immunodeficiency virus type 1 RNA.Virology 213(2) (1995) 373\u201385 77","journal-title":"Virology"},{"key":"7_CR16","doi-asserted-by":"crossref","first-page":"1147","DOI":"10.1038\/81125","volume":"18","author":"B Palsson","year":"2000","unstructured":"Palsson, B.:The challenges of in silico biology. Nature Biotechnology 18 (2000) 1147\u20131150 76","journal-title":"Nature Biotechnology"},{"issue":"11","key":"7_CR17","doi-asserted-by":"crossref","first-page":"6365","DOI":"10.1128\/JVI.67.11.6365-6378.1993","volume":"67","author":"D.F. Purcell","year":"1993","unstructured":"Purcell, D.F., Martin, M.A.:Alternative plicing of human immunodeficiency virus type 1 mRNA modulate viral protein expression, replication, and infectivity. J.Virol.67(11) (1993) 6365\u20136378 77","journal-title":"J.Virol."},{"unstructured":"Ropers, D., Ayadi, L., Jacquenet, S., M\u00e9reau, A., Thomas, D., Mougin, A., Bilodeau, P., Stoltzfus, C.M., Gattoni, R., St\u00e9venin, J., Branlant, C.:A complex regulation of the central A3 to A5 acceptor site in HIV-1 RNA. In Eukaryotic mRNA Processing (2001) 77","key":"7_CR18"},{"doi-asserted-by":"crossref","unstructured":"Saraswat, V.A.:Concurrent constraint programming. ACM Doctoral Dissertation Award. MIT Press (1993)81","key":"7_CR19","DOI":"10.7551\/mitpress\/2086.001.0001"},{"doi-asserted-by":"crossref","unstructured":"Saraswat, V.A., Jagadeesan, R., Gupta, V.:Foundation of timed concurrent constraint programming. In 9th Symp.Logic in Computer Science,LICS\u2019 94, Paris IEEE (1994) 71\u201380 81","key":"7_CR20","DOI":"10.1109\/LICS.1994.316085"},{"issue":"5","key":"7_CR21","doi-asserted-by":"publisher","first-page":"475","DOI":"10.1006\/jsco.1996.0064","volume":"22","author":"V.A. Saraswat","year":"1996","unstructured":"Saraswat, V.A., Jagadeesan, R., Gupta, V.:Timed default concurrent constraint programming. Journal of Symbolic Computation 22(5\/6) (1996) 475\u2013520 81","journal-title":"Journal of Symbolic Computation"},{"unstructured":"Segel, L.A.:Modelling dynamic phenomena in molecular and cellular biology. Cambridge University Press (1984)78","key":"7_CR22"},{"issue":"4","key":"7_CR23","doi-asserted-by":"publisher","first-page":"861","DOI":"10.1093\/nar\/25.4.861","volume":"25","author":"Z.H. Si","year":"1997","unstructured":"Si, Z.H., Amendt, B.A., Stoltzfus, C.M.:Splicing efficiency of human immunodeficiency virus type 1 tat RNA is determined by both a uboptimal 3\u2019 splice site and a 10 nucleotide exon splicing ilencer element located within tat exon 2. N.A.R.25(4) (1997) 861\u2013867","journal-title":"N.A.R."},{"issue":"9","key":"7_CR24","doi-asserted-by":"crossref","first-page":"5404","DOI":"10.1128\/MCB.18.9.5404","volume":"18","author":"Z.H. Si","year":"1998","unstructured":"Si, Z.H., Rauch, D., Stoltzfus, C.M.:The exon splicing silencer in human immunodeficiency virus type 1 Tat exon 3 i bipartite and acts early in spliceosomeassembly. Mol.Cell.Biol 18(9) (1998) 5404\u201313","journal-title":"Mol.Cell.Biol"},{"issue":"5","key":"7_CR25","doi-asserted-by":"crossref","first-page":"3071","DOI":"10.1128\/JVI.68.5.3071-3079.1994","volume":"68","author":"A. Staffa","year":"1994","unstructured":"Staffa, A., Cochrane, A.:The tat\/rev intron of human immunodeficiency virus type 1 i ineffciently spliced because of suboptimal signals in the 3\u2019 splice site. J. Virol.68(5) (1994) 3071\u20139","journal-title":"J. Virol."},{"key":"7_CR26","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1146\/annurev.genet.33.1.133","volume":"33","author":"H. Tang","year":"1999","unstructured":"Tang, H., Kuhen, K.L., Wong-Staal, F.:Lentivirus replication and regulation.Annu.Rev.Genet 33 (1999)133\u2013170 76","journal-title":"Annu.Rev.Genet"},{"unstructured":"Voit, E.:Computational Analysis of Biochemical Systems. Cambridge University Press (2000)79","key":"7_CR27"}],"container-title":["Lecture Notes in Computer Science","Computational Methods in Systems Biology"],"original-title":[],"link":[{"URL":"http:\/\/link.springer.com\/content\/pdf\/10.1007\/3-540-36481-1_7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,23]],"date-time":"2020-04-23T04:02:47Z","timestamp":1587614567000},"score":1,"resource":{"primary":{"URL":"http:\/\/link.springer.com\/10.1007\/3-540-36481-1_7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003]]},"ISBN":["9783540006053","9783540364818"],"references-count":27,"URL":"https:\/\/doi.org\/10.1007\/3-540-36481-1_7","relation":{},"ISSN":["0302-9743"],"issn-type":[{"type":"print","value":"0302-9743"}],"subject":[],"published":{"date-parts":[[2003]]}}}